Project measure / variable:   Auwerx1   vo2_night_HFD

ID, description, units MPD:111241   vo2_night_HFD   oxygen consumption, 24h period, during night   [mL/kg/min]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   48 strains     sex: m     age: 16wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Auwerx1 - oxygen consumption, 24h period, during night HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested48 strains
Mean of the strain means2979.0   mL/kg/min
Median of the strain means2902.0   mL/kg/min
SD of the strain means± 517.5
Coefficient of variation (CV)0.1737
Min–max range of strain means1947.0   –   4510.0   mL/kg/min
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 47 59893525.14 1274330.3221 12.7529 < 0.0001
Residuals 171 17087142.65 99924.8108


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 2744.0 395.0   5 176.6 0.144 2228.0, 3327.0 -0.45
BXD100 m 3163.0 277.1   5 123.9 0.0876 2842.0, 3513.0 0.36
BXD11 m 3000.0 272.8   5 122.0 0.0909 2650.0, 3277.0 0.04
BXD12 m 4250.0 335.0   5 149.8 0.0788 3888.0, 4636.0 2.46
BXD16 m 2558.0 174.0   5 77.83 0.068 2388.0, 2758.0 -0.81
BXD2 m 2824.0 210.3   5 94.04 0.0745 2590.0, 3035.0 -0.3
BXD27 m 2599.0 269.9   4 135.0 0.1039 2443.0, 3003.0 -0.73
BXD32 m 2541.0 142.2   4 71.12 0.056 2429.0, 2738.0 -0.85
BXD34 m 3372.0 461.2   5 206.2 0.1367 2815.0, 4046.0 0.76
BXD40 m 3626.0 303.6   4 151.8 0.0837 3240.0, 3952.0 1.25
BXD43 m 3324.0 262.3   3 151.4 0.0789 3041.0, 3559.0 0.67
BXD44 m 2151.0 229.5   9 76.49 0.1067 1926.0, 2518.0 -1.6
BXD45 m 3513.0 219.6   4 109.8 0.0625 3200.0, 3697.0 1.03
BXD48 m 1947.0 79.62   4 39.808 0.0409 1839.0, 2031.0 -1.99
BXD48a m 2497.0 153.8   4 76.91 0.0616 2281.0, 2629.0 -0.93
BXD49 m 2257.0 116.6   4 58.3 0.0517 2115.0, 2396.0 -1.39
BXD51 m 2711.0 222.4   4 111.2 0.082 2454.0, 2993.0 -0.52
BXD53 m 2962.0 814.3   5 364.2 0.2749 1579.0, 3742.0 -0.03
BXD55 m 4510.0 417.9   5 186.9 0.0927 3929.0, 4923.0 2.96
BXD6 m 3121.0 366.0   5 163.7 0.1172 2654.0, 3455.0 0.28
BXD60 m 2083.0 104.7   5 46.816 0.0503 1989.0, 2219.0 -1.73
BXD61 m 2589.0 86.87   5 38.848 0.0336 2492.0, 2688.0 -0.75
BXD62 m 2673.0 149.1   4 74.57 0.0558 2499.0, 2814.0 -0.59
BXD63 m 2814.0 118.7   4 59.33 0.0422 2697.0, 2917.0 -0.32
BXD64 m 2910.0 198.2   4 99.12 0.0681 2734.0, 3188.0 -0.13
BXD65 m 2630.0 305.1   4 152.6 0.116 2199.0, 2915.0 -0.67
BXD65a m 3070.0 216.4   4 108.2 0.0705 2888.0, 3331.0 0.18
BXD66 m 2648.0 287.1   5 128.4 0.1084 2353.0, 3083.0 -0.64
BXD67 m 2898.0 100.7   5 45.026 0.0347 2808.0, 3034.0 -0.16
BXD68 m 3668.0 325.5   4 162.8 0.0887 3199.0, 3952.0 1.33
BXD69 m 2914.0 344.9   5 154.2 0.1183 2423.0, 3326.0 -0.12
BXD70 m 3595.0 778.1   4 389.1 0.2165 3128.0, 4759.0 1.19
BXD73 m 3419.0 288.1   5 128.8 0.0843 2958.0, 3750.0 0.85
BXD73a m 3504.0 457.1   5 204.4 0.1305 2727.0, 3925.0 1.02
BXD73b m 2905.0 331.5   5 148.2 0.1141 2405.0, 3225.0 -0.14
BXD75 m 2836.0 325.9   5 145.7 0.1149 2314.0, 3211.0 -0.28
BXD77 m 2653.0 361.0   5 161.5 0.1361 2258.0, 3223.0 -0.63
BXD8 m 3105.0 443.5   5 198.3 0.1428 2359.0, 3410.0 0.24
BXD83 m 3683.0 252.5   4 126.3 0.0686 3425.0, 3948.0 1.36
BXD84 m 2694.0 109.2   4 54.59 0.0405 2587.0, 2821.0 -0.55
BXD85 m 2648.0 231.0   4 115.5 0.0872 2311.0, 2835.0 -0.64
BXD87 m 3632.0 259.8   4 129.9 0.0715 3380.0, 3942.0 1.26
BXD89 m 3145.0 149.2   4 74.59 0.0474 3037.0, 3365.0 0.32
BXD90 m 2698.0 177.8   4 88.89 0.0659 2546.0, 2942.0 -0.54
BXD98 m 2621.0 201.7   5 90.21 0.077 2421.0, 2837.0 -0.69
BXD99 m 2771.0 167.3   5 74.81 0.0604 2589.0, 2946.0 -0.4
C57BL/6J m 3460.0 438.4   4 219.2 0.1267 2972.0, 3832.0 0.93
DBA/2J m 3038.0 252.9   4 126.4 0.0832 2771.0, 3381.0 0.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 2743.6 141.3681794597 3022.6514494652 2464.5485505348
BXD100 m 3163.2 141.3681794597 3442.2514494652 2884.1485505348
BXD11 m 3000.2 141.3681794597 3279.2514494652 2721.1485505348
BXD12 m 4249.6 141.3681794597 4528.6514494652 3970.5485505348
BXD16 m 2558.2 141.3681794597 2837.2514494652 2279.1485505348
BXD2 m 2823.8 141.3681794597 3102.8514494652 2544.7485505348
BXD27 m 2598.75 158.0544295636 2910.739005112 2286.760994888
BXD32 m 2541.0 158.0544295636 2852.989005112 2229.010994888
BXD34 m 3372.4 141.3681794597 3651.4514494652 3093.3485505348
BXD40 m 3625.5 158.0544295636 3937.489005112 3313.510994888
BXD43 m 3324.0 182.5055349103 3684.2538721712 2963.7461278288
BXD44 m 2150.6666666667 105.3696197091 2358.6593367413 1942.673996592
BXD45 m 3513.25 158.0544295636 3825.239005112 3201.260994888
BXD48 m 1947.0 158.0544295636 2258.989005112 1635.010994888
BXD48a m 2497.25 158.0544295636 2809.239005112 2185.260994888
BXD49 m 2257.0 158.0544295636 2568.989005112 1945.010994888
BXD51 m 2710.75 158.0544295636 3022.739005112 2398.760994888
BXD53 m 2961.8 141.3681794597 3240.8514494652 2682.7485505348
BXD55 m 4510.0 141.3681794597 4789.0514494652 4230.9485505348
BXD6 m 3121.4 141.3681794597 3400.4514494652 2842.3485505348
BXD60 m 2083.0 141.3681794597 2362.0514494652 1803.9485505348
BXD61 m 2589.0 141.3681794597 2868.0514494652 2309.9485505348
BXD62 m 2673.0 158.0544295636 2984.989005112 2361.010994888
BXD63 m 2813.75 158.0544295636 3125.739005112 2501.760994888
BXD64 m 2909.75 158.0544295636 3221.739005112 2597.760994888
BXD65 m 2630.0 158.0544295636 2941.989005112 2318.010994888
BXD65a m 3070.0 158.0544295636 3381.989005112 2758.010994888
BXD66 m 2648.0 141.3681794597 2927.0514494652 2368.9485505348
BXD67 m 2897.6 141.3681794597 3176.6514494652 2618.5485505348
BXD68 m 3668.25 158.0544295636 3980.239005112 3356.260994888
BXD69 m 2914.2 141.3681794597 3193.2514494652 2635.1485505348
BXD70 m 3595.0 158.0544295636 3906.989005112 3283.010994888
BXD73 m 3419.0 141.3681794597 3698.0514494652 3139.9485505348
BXD73a m 3504.2 141.3681794597 3783.2514494652 3225.1485505348
BXD73b m 2904.8 141.3681794597 3183.8514494652 2625.7485505348
BXD75 m 2836.4 141.3681794597 3115.4514494652 2557.3485505348
BXD77 m 2653.4 141.3681794597 2932.4514494652 2374.3485505348
BXD8 m 3105.0 141.3681794597 3384.0514494652 2825.9485505348
BXD83 m 3682.75 158.0544295636 3994.739005112 3370.760994888
BXD84 m 2693.5 158.0544295636 3005.489005112 2381.510994888
BXD85 m 2648.25 158.0544295636 2960.239005112 2336.260994888
BXD87 m 3632.25 158.0544295636 3944.239005112 3320.260994888
BXD89 m 3144.75 158.0544295636 3456.739005112 2832.760994888
BXD90 m 2698.0 158.0544295636 3009.989005112 2386.010994888
BXD98 m 2621.2 141.3681794597 2900.2514494652 2342.1485505348
BXD99 m 2770.8 141.3681794597 3049.8514494652 2491.7485505348
C57BL/6J m 3460.0 158.0544295636 3771.989005112 3148.010994888
DBA/2J m 3038.0 158.0544295636 3349.989005112 2726.010994888




  GWAS USING LINEAR MIXED MODELS