Project measure / variable:   Auwerx1   vo2_day_CD

ID, description, units MPD:111238   vo2_day_CD   oxygen consumption, 24h period, during day   [mL/kg/min]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   53 strains     sex: m     age: 16wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Auwerx1 - oxygen consumption, 24h period, during day CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested53 strains
Mean of the strain means2534.0   mL/kg/min
Median of the strain means2515.0   mL/kg/min
SD of the strain means± 336.6
Coefficient of variation (CV)0.1328
Min–max range of strain means1744.0   –   3391.0   mL/kg/min
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 52 25594584.8615 492203.555 8.553 < 0.0001
Residuals 188 10818935.0556 57547.5269


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 2510.0 162.6   5 72.71 0.0648 2332.0, 2683.0 -0.07
BXD100 m 2545.0 445.8   3 257.4 0.1752 2066.0, 2948.0 0.03
BXD11 m 2962.0 773.4   4 386.7 0.2611 1953.0, 3653.0 1.27
BXD12 m 3038.0 224.5   5 100.4 0.0739 2810.0, 3351.0 1.5
BXD16 m 2068.0 97.8   5 43.736 0.0473 1950.0, 2217.0 -1.38
BXD2 m 2614.0 377.3   4 188.7 0.1443 2250.0, 2972.0 0.24
BXD27 m 2122.0 184.7   5 82.58 0.087 1935.0, 2332.0 -1.22
BXD32 m 2585.0 183.8   5 82.18 0.0711 2397.0, 2801.0 0.15
BXD34 m 2592.0 195.8   4 97.92 0.0756 2377.0, 2762.0 0.17
BXD39 m 2237.0 235.8   5 105.4 0.1054 2009.0, 2497.0 -0.88
BXD40 m 2789.0 342.5   3 197.8 0.1228 2565.0, 3183.0 0.76
BXD43 m 2940.0 217.9   5 97.46 0.0741 2673.0, 3216.0 1.21
BXD44 m 2292.0 334.6   9 111.5 0.146 1732.0, 2696.0 -0.72
BXD45 m 2793.0 265.3   4 132.6 0.095 2547.0, 3116.0 0.77
BXD48 m 1762.0 77.19   4 38.597 0.0438 1660.0, 1845.0 -2.29
BXD48a m 2373.0 153.5   5 68.64 0.0647 2157.0, 2548.0 -0.48
BXD49 m 1744.0 121.8   4 60.88 0.0698 1581.0, 1864.0 -2.35
BXD50 m 2569.0 239.5   5 107.1 0.0932 2296.0, 2888.0 0.1
BXD51 m 2872.0 409.5   4 204.8 0.1426 2377.0, 3370.0 1.0
BXD53 m 2754.0 271.0   5 121.2 0.0984 2511.0, 3164.0 0.65
BXD55 m 2775.0 230.9   5 103.3 0.0832 2466.0, 3107.0 0.72
BXD6 m 2959.0 172.2   5 77.02 0.0582 2690.0, 3162.0 1.26
BXD60 m 2586.0 331.4   5 148.2 0.1282 2159.0, 3039.0 0.16
BXD61 m 2736.0 137.7   3 79.5 0.0503 2577.0, 2816.0 0.6
BXD62 m 2452.0 36.473   4 18.236 0.0149 2405.0, 2491.0 -0.24
BXD63 m 2519.0 108.1   5 48.35 0.0429 2347.0, 2643.0 -0.04
BXD64 m 2384.0 133.4   4 66.7 0.056 2219.0, 2530.0 -0.44
BXD65 m 2384.0 108.1   4 54.04 0.0453 2253.0, 2517.0 -0.44
BXD65a m 2469.0 156.3   5 69.88 0.0633 2201.0, 2594.0 -0.19
BXD65b m 2196.0 172.3   4 86.17 0.0785 2018.0, 2426.0 -1.0
BXD66 m 2059.0 233.9   5 104.6 0.1136 1788.0, 2406.0 -1.41
BXD67 m 2394.0 91.81   5 41.06 0.0384 2324.0, 2554.0 -0.42
BXD68 m 2515.0 263.6   5 117.9 0.1048 2110.0, 2776.0 -0.06
BXD69 m 2177.0 151.2   4 75.61 0.0695 2014.0, 2365.0 -1.06
BXD70 m 2494.0 544.7   4 272.4 0.2184 1946.0, 3128.0 -0.12
BXD71 m 2349.0 108.3   5 48.415 0.0461 2218.0, 2506.0 -0.55
BXD73 m 2696.0 273.2   5 122.2 0.1014 2407.0, 3060.0 0.48
BXD73a m 2322.0 164.8   5 73.7 0.071 2105.0, 2492.0 -0.63
BXD73b m 2303.0 143.9   5 64.36 0.0625 2070.0, 2440.0 -0.69
BXD75 m 2335.0 131.6   5 58.84 0.0564 2176.0, 2499.0 -0.59
BXD77 m 2375.0 103.7   5 46.371 0.0437 2213.0, 2481.0 -0.47
BXD8 m 2918.0 172.5   4 86.23 0.0591 2714.0, 3136.0 1.14
BXD83 m 2940.0 169.1   3 97.65 0.0575 2767.0, 3105.0 1.21
BXD84 m 2154.0 145.9   5 65.24 0.0677 1936.0, 2323.0 -1.13
BXD85 m 2062.0 170.6   5 76.28 0.0827 1800.0, 2224.0 -1.4
BXD87 m 3391.0 64.91   4 32.453 0.0191 3308.0, 3449.0 2.55
BXD89 m 2504.0 202.0   4 101.0 0.0807 2282.0, 2720.0 -0.09
BXD90 m 3004.0 187.3   4 93.66 0.0624 2747.0, 3161.0 1.4
BXD95 m 2618.0 302.6   4 151.3 0.1156 2358.0, 3047.0 0.25
BXD98 m 2473.0 234.5   5 104.9 0.0948 2250.0, 2837.0 -0.18
BXD99 m 2673.0 132.6   5 59.31 0.0496 2511.0, 2819.0 0.41
C57BL/6J m 2702.0 134.5   4 67.27 0.0498 2577.0, 2837.0 0.5
DBA/2J m 3209.0 129.2   4 64.6 0.0403 3029.0, 3330.0 2.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 2509.6 107.282362848 2721.2319147408 2297.9680852592
BXD100 m 2544.6666666666 138.500934884 2817.8822937723 2271.451039561
BXD11 m 2961.75 119.9453280575 3198.3616737844 2725.1383262156
BXD12 m 3037.8 107.282362848 3249.4319147408 2826.1680852592
BXD16 m 2068.0 107.282362848 2279.6319147408 1856.3680852592
BXD2 m 2614.25 119.9453280575 2850.8616737844 2377.6383262156
BXD27 m 2121.6 107.282362848 2333.2319147408 1909.9680852592
BXD32 m 2584.6 107.282362848 2796.2319147408 2372.9680852592
BXD34 m 2592.0 119.9453280575 2828.6116737844 2355.3883262156
BXD39 m 2237.2 107.282362848 2448.8319147408 2025.5680852592
BXD40 m 2788.6666666667 138.500934884 3061.8822937723 2515.451039561
BXD43 m 2940.2 107.282362848 3151.8319147408 2728.5680852592
BXD44 m 2292.4444444444 79.9635520383 2450.1855603007 2134.7033285882
BXD45 m 2792.75 119.9453280575 3029.3616737844 2556.1383262156
BXD48 m 1762.5 119.9453280575 1999.1116737844 1525.8883262156
BXD48a m 2372.8 107.282362848 2584.4319147408 2161.1680852592
BXD49 m 1743.5 119.9453280575 1980.1116737844 1506.8883262156
BXD50 m 2568.8 107.282362848 2780.4319147408 2357.1680852592
BXD51 m 2872.25 119.9453280575 3108.8616737844 2635.6383262156
BXD53 m 2753.6 107.282362848 2965.2319147408 2541.9680852592
BXD55 m 2774.6 107.282362848 2986.2319147408 2562.9680852592
BXD6 m 2958.6 107.282362848 3170.2319147408 2746.9680852592
BXD60 m 2585.6 107.282362848 2797.2319147408 2373.9680852592
BXD61 m 2736.0 138.500934884 3009.2156271057 2462.7843728943
BXD62 m 2452.25 119.9453280575 2688.8616737844 2215.6383262156
BXD63 m 2518.8 107.282362848 2730.4319147408 2307.1680852592
BXD64 m 2383.5 119.9453280575 2620.1116737844 2146.8883262156
BXD65 m 2384.5 119.9453280575 2621.1116737844 2147.8883262156
BXD65a m 2469.2 107.282362848 2680.8319147408 2257.5680852592
BXD65b m 2195.75 119.9453280575 2432.3616737844 1959.1383262156
BXD66 m 2059.4 107.282362848 2271.0319147408 1847.7680852592
BXD67 m 2394.0 107.282362848 2605.6319147408 2182.3680852592
BXD68 m 2515.2 107.282362848 2726.8319147408 2303.5680852592
BXD69 m 2177.0 119.9453280575 2413.6116737844 1940.3883262156
BXD70 m 2494.25 119.9453280575 2730.8616737844 2257.6383262156
BXD71 m 2349.0 107.282362848 2560.6319147408 2137.3680852592
BXD73 m 2695.6 107.282362848 2907.2319147408 2483.9680852592
BXD73a m 2321.6 107.282362848 2533.2319147408 2109.9680852592
BXD73b m 2303.0 107.282362848 2514.6319147408 2091.3680852592
BXD75 m 2334.6 107.282362848 2546.2319147408 2122.9680852592
BXD77 m 2375.4 107.282362848 2587.0319147408 2163.7680852592
BXD8 m 2918.5 119.9453280575 3155.1116737844 2681.8883262156
BXD83 m 2940.0 138.500934884 3213.2156271057 2666.7843728943
BXD84 m 2154.4 107.282362848 2366.0319147408 1942.7680852592
BXD85 m 2062.0 107.282362848 2273.6319147408 1850.3680852592
BXD87 m 3391.25 119.9453280575 3627.8616737844 3154.6383262156
BXD89 m 2503.5 119.9453280575 2740.1116737844 2266.8883262156
BXD90 m 3003.75 119.9453280575 3240.3616737844 2767.1383262156
BXD95 m 2618.0 119.9453280575 2854.6116737844 2381.3883262156
BXD98 m 2473.2 107.282362848 2684.8319147408 2261.5680852592
BXD99 m 2672.6 107.282362848 2884.2319147408 2460.9680852592
C57BL/6J m 2702.0 119.9453280575 2938.6116737844 2465.3883262156
DBA/2J m 3208.75 119.9453280575 3445.3616737844 2972.1383262156




  GWAS USING LINEAR MIXED MODELS