Project measure / variable:   CSNA03   reward_time_in_acq_JAX

ID, description, units MPD:110477   reward_time_in_acq_JAX   latency to retrieve reward per total correct responses (reversal learning assay), founders   [centiseconds/n]  acquisition  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - latency to retrieve reward per total correct responses (reversal learning assay), founders acquisition



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means193.4   centiseconds/n 202.6   centiseconds/n
Median of the strain means188.3   centiseconds/n 209.6   centiseconds/n
SD of the strain means± 53.32 ± 51.99
Coefficient of variation (CV)0.2757 0.2566
Min–max range of strain means119.9   –   265.9   centiseconds/n 125.5   –   255.9   centiseconds/n
Mean sample size per strain7.6   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1958.4428 1958.4428 0.6347 0.4275
strain 7 243825.9073 34832.2725 11.2884 < 0.0001
sex:strain 7 13653.8308 1950.5473 0.6321 0.7283
Residuals 100 308566.7024 3085.667


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 175.6 41.472   3 23.944 0.2362 134.9, 217.8 -0.33
129S1/SvImJ m 173.6 54.79   4 27.393 0.3155 95.22, 213.4 -0.56
A/J f 265.9 81.69   6 33.349 0.3072 160.9, 358.4 1.36
A/J m 244.1 58.25   5 26.049 0.2386 184.6, 323.6 0.8
C57BL/6J f 244.1 63.86   14 17.067 0.2616 149.5, 365.1 0.95
C57BL/6J m 253.7 80.42   11 24.247 0.3169 135.1, 442.6 0.98
CAST/EiJ f 201.1 22.808   10 7.2126 0.1134 160.8, 237.7 0.14
CAST/EiJ m 255.9 54.99   8 19.441 0.2149 158.0, 314.1 1.02
NOD/ShiLtJ f 119.9 34.203   8 12.093 0.2853 88.26, 194.7 -1.38
NOD/ShiLtJ m 149.2 64.07   11 19.318 0.4294 86.43, 304.6 -1.03
NZO/HlLtJ f 131.9 23.565   3 13.605 0.1787 108.8, 155.9 -1.15
NZO/HlLtJ m 125.5 45.92   2   32.47 0.3658 93.06, 158.0 -1.48
PWK/PhJ f 238.0 60.04   9 20.013 0.2523 141.2, 330.8 0.84
PWK/PhJ m 241.3 42.209   8 14.923 0.1749 164.2, 319.2 0.74
WSB/EiJ f 170.5 32.812   8 11.601 0.1925 134.9, 224.4 -0.43
WSB/EiJ m 177.8 29.503   6 12.045 0.1659 149.6, 225.7 -0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 175.5666666667 32.0711034206 239.1948224207 111.9385109126
129S1/SvImJ m 173.63 27.7743902896 228.733599279 118.526400721
A/J f 265.9166666667 22.6776947088 310.9085670748 220.9247662586
A/J m 244.08 24.8421698885 293.3661575171 194.7938424829
C57BL/6J f 244.1285714286 14.8460360843 273.5826841829 214.6744586743
C57BL/6J m 253.7454545455 16.7485875221 286.9741751648 220.5167339261
CAST/EiJ f 201.14 17.5660667875 235.990576199 166.289423801
CAST/EiJ m 255.9 19.6394597171 294.8641287179 216.9358712821
NOD/ShiLtJ f 119.89125 19.6394597171 158.8553787179 80.9271212821
NOD/ShiLtJ m 149.2181818182 16.7485875221 182.4469024375 115.9894611988
NZO/HlLtJ f 131.8666666667 32.0711034206 195.4948224207 68.2385109126
NZO/HlLtJ m 125.53 39.2789194342 203.4582574359 47.6017425641
PWK/PhJ f 238.0111111111 18.5162601931 274.7468439638 201.2753782585
PWK/PhJ m 241.35 19.6394597171 280.3141287179 202.3858712821
WSB/EiJ f 170.45 19.6394597171 209.4141287179 131.4858712821
WSB/EiJ m 177.8333333333 22.6776947088 222.8252337414 132.8414329252


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 174.5983333333 21.2130409806 216.6844024601 132.5122642066
A/J both 254.9983333333 16.818228519 288.3652197071 221.6314469595
C57BL/6J both 248.937012987 11.1906207536 271.1388858367 226.7351401373
CAST/EiJ both 228.52 13.1745500907 254.6579321492 202.3820678508
NOD/ShiLtJ both 134.5547159091 12.9056534314 160.1591647449 108.9502670733
NZO/HlLtJ both 128.6983333333 25.354433471 179.000807208 78.3958594586
PWK/PhJ both 239.6805555556 13.4959278073 266.4560919413 212.9050191698
WSB/EiJ both 174.1416666667 14.999885127 203.9010115397 144.3823217937




  GWAS USING LINEAR MIXED MODELS