Project measure / variable:   CSNA03   trial_init_latency_in_acq_JAX

ID, description, units MPD:110473   trial_init_latency_in_acq_JAX   mean latency (across trials) between illumination of central hole and initiation of trial (reversal learning assay), founders   [centiseconds/n]  acquisition  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - mean latency (across trials) between illumination of central hole and initiation of trial (reversal learning assay), founders acquisition



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means539.3   centiseconds/n 372.8   centiseconds/n
Median of the strain means371.1   centiseconds/n 352.6   centiseconds/n
SD of the strain means± 481.4 ± 207.9
Coefficient of variation (CV)0.8926 0.5575
Min–max range of strain means189.2   –   1651.0   centiseconds/n 71.74   –   759.8   centiseconds/n
Mean sample size per strain7.6   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 73087.6093 73087.6093 1.0852 0.3001
strain 7 5016980.8286 716711.5469 10.6416 < 0.0001
sex:strain 7 2584355.2808 369193.6115 5.4817 < 0.0001
Residuals 100 6734969.8225 67349.6982


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1651.0 544.9   3 314.6 0.33 1276.0, 2276.0 2.31
129S1/SvImJ m 548.9 362.2   4 181.1 0.6599 224.7, 1019.0 0.85
A/J f 711.1 321.6   6 131.3 0.4523 140.0, 1067.0 0.36
A/J m 759.8 273.8   5 122.4 0.3603 596.1, 1240.0 1.86
C57BL/6J f 373.3 163.0   14 43.554 0.4365 95.32, 734.7 -0.34
C57BL/6J m 215.0 115.6   11 34.848 0.5375 31.4, 421.9 -0.76
CAST/EiJ f 189.2 78.86   10 24.939 0.4169 66.19, 356.0 -0.73
CAST/EiJ m 330.7 286.2   8 101.2 0.8653 74.05, 786.8 -0.2
NOD/ShiLtJ f 254.5 255.9   8 90.47 1.0056 53.92, 655.4 -0.59
NOD/ShiLtJ m 307.1 269.2   11 81.16 0.8765 58.95, 992.9 -0.32
NZO/HlLtJ f 537.3 621.1   3 358.6 1.1558 128.3, 1252.0 0.0
NZO/HlLtJ m 71.74 0.14142   2   0.1 0.002 71.64, 71.84 -1.45
PWK/PhJ f 229.0 137.4   9 45.811 0.6002 96.05, 462.5 -0.64
PWK/PhJ m 374.7 185.6   8 65.61 0.4952 82.43, 703.5 0.01
WSB/EiJ f 368.8 427.4   8 151.1 1.1591 50.56, 1264.0 -0.35
WSB/EiJ m 374.6 198.5   6 81.02 0.5298 144.8, 705.0 0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1651.0 149.8329049588 1948.2642159758 1353.7357840242
129S1/SvImJ m 548.85 129.7591020171 806.2883626711 291.4116373289
A/J f 711.1 105.9478631412 921.2975429206 500.9024570794
A/J m 759.82 116.0600691238 990.0798715796 529.5601284204
C57BL/6J f 373.33 69.3591575091 510.9365930468 235.7234069532
C57BL/6J m 215.0472727273 78.2476826408 370.288446477 59.8060989775
CAST/EiJ f 189.159 82.0668619024 351.977316629 26.340683371
CAST/EiJ m 330.73625 91.753540957 512.7726619823 148.6998380177
NOD/ShiLtJ f 254.47 91.753540957 436.5064119823 72.4335880177
NOD/ShiLtJ m 307.1036363636 78.2476826408 462.3448101134 151.8624626139
NZO/HlLtJ f 537.3333333333 149.8329049588 834.5975493092 240.0691173575
NZO/HlLtJ m 71.74 183.5070819139 435.8128239646 -292.3328239646
PWK/PhJ f 228.9655555556 86.5060680114 400.5911306696 57.3399804415
PWK/PhJ m 374.72875 91.753540957 556.7651619823 192.6923380177
WSB/EiJ f 368.77375 91.753540957 550.8101619823 186.7373380177
WSB/EiJ m 374.6 105.9478631412 584.7975429206 164.4024570794


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1099.925 99.1051511838 1296.5467972877 903.3032027123
A/J both 735.46 78.5730382339 891.3466699799 579.5733300201
C57BL/6J both 294.1886363636 52.2814320983 397.9135085944 190.4637641329
CAST/EiJ both 259.947625 61.5501464268 382.0613624718 137.8338875282
NOD/ShiLtJ both 280.7868181818 60.2938888213 400.4081763443 161.1654600193
NZO/HlLtJ both 304.5366666667 118.4533120273 539.5446640036 69.5286693297
PWK/PhJ both 301.8471527778 63.0515901483 426.9397118297 176.7545937259
WSB/EiJ both 371.686875 70.0779244526 510.7194811912 232.6542688088




  GWAS USING LINEAR MIXED MODELS