ITP survival analysis: green tea extract
Results are based on the use of pooled factor(s) that is/are stratified within the survival analysis model.
All test sites combined – female
Survival analysis details -- Female
GTE effect on survival,
females, test site = All
Log-rank test
chisq = 0.8084
p = 0.3686
Wang-Allison test
odds ratio = 0.8379
p = 0.7276
Quantiles
GTE
Control
% difference
25% died before day:
821
753
+9 %
Median lifespan (days)
923
865
+7 %
75% died before day:
999
994
+1 %
90% died before day:
1075
1088
-1 %
Max lifespan observed (days)
1262
1359
Number of mice at start
129
275
Animal censor events are denoted by + marks in the plot
All test sites combined – male
Survival analysis details -- Male
GTE effect on survival,
males, test site = All
Log-rank test
chisq = 0.7324
p = 0.3921
Wang-Allison test
odds ratio = 1.4274
p = 0.3099
Quantiles
GTE
Control
% difference
25% died before day:
628
588
+7 %
Median lifespan (days)
822
784
+5 %
75% died before day:
969
954
+2 %
90% died before day:
1084
1074
+1 %
Max lifespan observed (days)
1325
1247
Number of mice at start
145
276
Animal censor events are denoted by + marks in the plot
By individual test site:
TJL – female
TJL – female
Survival analysis details
GTE effect on survival,
females, test site = TJL
Log-rank test
chisq = 0.0045
p = 0.9464
Wang-Allison test
odds ratio = 0.3274
p = 0.2245
Quantiles
GTE
Control
% difference
25% died before day:
804
740
+9 %
Median lifespan (days)
937
860
+9 %
75% died before day:
1012
1016
0 %
90% died before day:
1083
1111
-3 %
Max lifespan observed (days)
1108
1340
Number of mice at start
43
92
Animal censor events are denoted by + marks in the plot
TJL – male
TJL – male
Survival analysis details
GTE effect on survival,
males, test site = TJL
Log-rank test
chisq = 0.2641
p = 0.6073
Wang-Allison test
odds ratio = 0.8358
p = 1.0
Quantiles
GTE
Control
% difference
25% died before day:
622
569
+9 %
Median lifespan (days)
768
728
+5 %
75% died before day:
934
923
+1 %
90% died before day:
1028
1039
-1 %
Max lifespan observed (days)
1159
1200
Number of mice at start
46
87
Animal censor events are denoted by + marks in the plot
UM – female
UM – female
Survival analysis details
GTE effect on survival,
females, test site = UM
Log-rank test
chisq = 0.0013
p = 0.9708
Wang-Allison test
odds ratio = 0.5617
p = 0.5471
Quantiles
GTE
Control
% difference
25% died before day:
835
767
+9 %
Median lifespan (days)
934
900
+4 %
75% died before day:
990
999
-1 %
90% died before day:
1053
1114
-5 %
Max lifespan observed (days)
1187
1359
Number of mice at start
42
91
Animal censor events are denoted by + marks in the plot
UM – male
UM – male
Survival analysis details
GTE effect on survival,
males, test site = UM
Log-rank test
chisq = 3.7499
p = 0.0528
Wang-Allison test
odds ratio = 3.0806
p = 0.0466
Quantiles
GTE
Control
% difference
25% died before day:
747
659
+13 %
Median lifespan (days)
887
793
+12 %
75% died before day:
1024
953
+7 %
90% died before day:
1129
1076
+5 %
Max lifespan observed (days)
1325
1191
Number of mice at start
51
93
Animal censor events are denoted by + marks in the plot
UT – female
UT – female
Survival analysis details
GTE effect on survival,
females, test site = UT
Log-rank test
chisq = 2.3387
p = 0.1262
Wang-Allison test
odds ratio = 2.2819
p = 0.1449
Quantiles
GTE
Control
% difference
25% died before day:
826
756
+9 %
Median lifespan (days)
908
840
+8 %
75% died before day:
970
962
+1 %
90% died before day:
1075
1045
+3 %
Max lifespan observed (days)
1262
1261
Number of mice at start
44
92
Animal censor events are denoted by + marks in the plot
UT – male
UT – male
Survival analysis details
GTE effect on survival,
males, test site = UT
Log-rank test
chisq = 1.1632
p = 0.2808
Wang-Allison test
odds ratio = 1.0
p = 1.0
Quantiles
GTE
Control
% difference
25% died before day:
568
584
-3 %
Median lifespan (days)
784
810
-3 %
75% died before day:
938
1010
-7 %
90% died before day:
1081
1132
-5 %
Max lifespan observed (days)
1192
1247
Number of mice at start
48
96
Animal censor events are denoted by + marks in the plot
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ITP data portal page for more information on
National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.
Statistical definitions