MPD: Measures involving diazepam

Data set	MPD ID	Procedure / Protocol	Drug or Challenge	Phenotype Measure	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Crabbe2	15501	drug and metabolite quantification	diazepam	brain diazepam and metabolite concentration, 30 min post-injection [ng/g] 8 mg/kg 16 mg/kg	inbred	15	m	6-7wks	N=8	1998

Crabbe2	15503	drug and metabolite quantification	diazepam	brain diazepam and metabolite concentration, <5 min post-injection, after rotarod [ng/g] trial block1 trial block2	inbred	8	m	6-7wks	N=13	1998

Crabbe2	15504	monitoring system	diazepam	horizontal distance traveled, immediately to 15 min post-injection [cm] baseline doses mg/kg: 2 4 8 16	inbred	15	m	6-7wks	N=8	1998

Crabbe2	15509	monitoring system	diazepam	vertical (rearing) activity, immediately to 15 min post-injection [n] baseline doses mg/kg: 2 4 8 16	inbred	15	m	6-7wks	N=8	1998

Crabbe2	15514	body temperature	diazepam	body temperature, 30 min post-injection [°C] baseline doses mg/kg: 2 4 8 16	inbred	15	m	6-7wks	N=8	1998

Crabbe2	15519	rotarod	diazepam	latency to fall from 5 rpm rotarod, 0 min post-injection [s] trial block1 trial block2	inbred	8	m	6-7wks	N=13	1998

Crabbe2

15501

drug and metabolite quantification

diazepam

brain diazepam and metabolite concentration, 30 min post-injection [ng/g] 8 mg/kg 16 mg/kg

inbred

15

m

6-7wks

N=8

1998

Crabbe2

15503

drug and metabolite quantification

diazepam

brain diazepam and metabolite concentration, <5 min post-injection, after rotarod [ng/g] trial block1 trial block2

inbred

8

m

6-7wks

N=13

1998

Crabbe2

15504

monitoring system

diazepam

horizontal distance traveled, immediately to 15 min post-injection [cm] baseline doses mg/kg: 2 4 8 16

inbred

15

m

6-7wks

N=8

1998

Crabbe2

15509

monitoring system

diazepam

vertical (rearing) activity, immediately to 15 min post-injection [n] baseline doses mg/kg: 2 4 8 16

inbred

15

m

6-7wks

N=8

1998

Crabbe2

15514

body temperature

diazepam

body temperature, 30 min post-injection [°C] baseline doses mg/kg: 2 4 8 16

inbred

15

m

6-7wks

N=8

1998

Crabbe2

15519

rotarod

diazepam

latency to fall from 5 rpm rotarod, 0 min post-injection [s] trial block1 trial block2

inbred

8

m

6-7wks

N=13

1998