MPD: Measures involving methacholine

Measures involving methacholine

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Ackerman1:1	Ackerman1	ventilator	methacholine	individual pulmonary resistance values, a percentage of baseline for the 100 µg/kg dose [%] RL100 15601	QTL population		f	7-8wks	N=372	2005

Ackerman1:2	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 330 µg/kg dose [%] RL330 15602	QTL population		f	7-8wks	N=372	2005

Ackerman1:3	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 1000 µg/kg dose [%] RL1000 15603	QTL population		f	7-8wks	N=372	2005

Ackerman1:4	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 3300 µg/kg dose [%] RL3300 15604	QTL population		f	7-8wks	N=372	2005

Ackerman1:5	Ackerman1	ventilator	methacholine	effective doses of methacholine required for a 1.50-fold increase in R_L), log transformed [log(n)] logED150 15605	QTL population		f	7-8wks	N=372	2005

Berndt1:10	Berndt1	ventilator	methacholine	airway resistance (H₂O pressure) [cm/mL/s] airway_res_series 34210 baseline MCh challenge (mg/mL): 1 3 10 30	inbred	37	both	9-12wks	N=8	2010

Berndt1:21	Berndt1	ventilator	methacholine	airway resistance (as % of baseline, H₂O pressure) [%] pct_res 34221 MCh challenge (mg/mL): 1 3 10 30	inbred	37	both	9-12wks	N=8	2010

Berndt2:1	Berndt2	plethysmography	methacholine	minute ventilation [mL/min] min_vent 35101 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:8	Berndt2	plethysmography	methacholine	breath frequency [n/min] breath_freq 35108 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:14	Berndt2	plethysmography	methacholine	inspiratory phase [s] inspiratory 35114 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:21	Berndt2	plethysmography	methacholine	expiratory phase [s] expiratory 35121 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:28	Berndt2	plethysmography	methacholine	respiratory cycle [s] tot_respi 35128 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:34	Berndt2	plethysmography	methacholine	duty cycle [ratio] duty_cycle 35134 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:41	Berndt2	plethysmography	methacholine	inspiratory flow rate [mL/kg/s] insp_flow 35141 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:48	Berndt2	plethysmography	methacholine	expiratory flow rate [mL/kg/s] exp_flow 35148 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:54	Berndt2	plethysmography	methacholine	respiratory flow rate [mL/kg/s] resp_flow 35154 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:61	Berndt2	plethysmography	methacholine	enhanced pause penh 35161 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:68	Berndt2	plethysmography	methacholine	tidal volume [mL] tidal_vol 35168 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:81	Berndt2	ventilator	methacholine	airway resistance (H₂0 pressure) [cm/mL/s] airway_res 35181 saline 1 MCh 3 MCh 10 MCh 30 MCh response index	inbred	29	both	9-12wks	N=9	2010

Berndt2:91	Berndt2	ventilator	methacholine	lung tissue dynamic elastance (H₂0 pressure) [cm/mL] airway_elas 35191 saline 1 MCh 3 MCh 10 MCh 30 MCh response index	inbred	29	both	9-12wks	N=9	2010

Other available data sets:

Data set	Procedure	What's in this data set	Panel	Sex	Age (weeks)	Year
Schwartz4	study archive	Lung, respiratory response to ozone. Methacholine-sensitized.	inbred (8)	both		2004

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