Project measures / variables set:   Berndt1   pct_res

ID, description, units MPD:34221   pct_res   airway resistance (as % of baseline, H2O pressure)   [%]  
methacholine study
Measures • MCh challenge (mg/mL):    • 1    • 3    • 10    • 30
Data set, strains Berndt1   inbred   37 strains     sex: both     age: 9-12wks
Procedure ventilator
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Berndt1 - airway resistance (as % of baseline, H2O pressure)



  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 111755.7788 111755.7788 11.8494 0.0007
between   strain 28 1190377.7702 42513.4918 4.5077 < 0.0001
between   sex:strain 28 508366.7729 18155.9562 1.9251 0.004
between   Residuals 327 3084040.8732 9431.3177
within   MCh 3 20172894.0722 6724298.0241 1523.6879 < 0.0001
within   MCh:sex 3 178220.1093 59406.7031 13.4612 < 0.0001
within   MCh:strain 84 1571420.9306 18707.392 4.239 < 0.0001
within   MCh:sex:strain 84 572232.9765 6812.2973 1.5436 0.0018
within   Residuals 981 4329322.6214 4413.1729

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Berndt1 34221 ventilator methacholine airway resistance (as % of baseline, H2O pressure)   [%]   MCh challenge 1 mg/mL  pct_res_mch1 inbred 37 both 9-12wks
Berndt1 34222 ventilator methacholine airway resistance (as % of baseline, H2O pressure)   [%]   MCh challenge 3 mg/mL  pct_res_mch3 inbred 37 both 9-12wks
Berndt1 34223 ventilator methacholine airway resistance (as % of baseline, H2O pressure)   [%]   MCh challenge 10 mg/mL  pct_res_mch10 inbred 37 both 9-12wks
Berndt1 34224 ventilator methacholine airway resistance (as % of baseline, H2O pressure)   [%]   MCh challenge 30 mg/mL  pct_res_mch30 inbred 37 both 9-12wks



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