Project measures / variables set:   Berndt1   airway_res_series

ID, description, units MPD:34210   airway_res_series   airway resistance (H2O pressure)   [cm/mL/s]  
methacholine study
Measures • baseline    • MCh challenge (mg/mL):    • 1    • 3    • 10    • 30
Data set, strains Berndt1   inbred   37 strains     sex: both     age: 9-12wks
Procedure ventilator
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Berndt1 - airway resistance (H2O pressure)



  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 3.4829 3.4829 22.9954 < 0.0001
between   strain 28 46.3255 1.6545 10.9234 < 0.0001
between   sex:strain 28 17.0996 0.6107 4.032 < 0.0001
between   Residuals 327 49.5283 0.1515
within   MCh 4 380.5433 95.1358 2060.3852 < 0.0001
within   MCh:sex 4 4.5914 1.1478 24.8593 < 0.0001
within   MCh:strain 112 22.1156 0.1975 4.2765 < 0.0001
within   MCh:sex:strain 112 9.0184 0.0805 1.7439 < 0.0001
within   Residuals 1308 60.3953 0.0462

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Berndt1 34210 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]   baseline  airway_res_saline inbred 37 both 9-12wks
Berndt1 34211 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]   MCh challenge 1 mg/mL  airway_res_mch1 inbred 37 both 9-12wks
Berndt1 34212 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]   MCh challenge 3 mg/mL  airway_res_mch3 inbred 37 both 9-12wks
Berndt1 34213 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]   MCh challenge 10 mg/mL  airway_res_mch10 inbred 37 both 9-12wks
Berndt1 34214 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]   MCh challenge 30 mg/mL  airway_res_mch30 inbred 37 both 9-12wks



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