| Data set | Procedure | What's in this data set | Panel | Sex | Age (weeks) | Year |
|---|---|---|---|---|---|---|
|
|
body size and weight | Body weight, body length, body mass index. Aging study, 6mo, 12mo, 20mo. | inbred (32) | both | 26, 52, 87 wks | 2008 |
|
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, body area, bone area. Aging study, 6mo, 12mo, 20mo. | inbred (32) | both | 26, 52, 87 wks | 2008 |
|
|
genotype assessment | Gpr84 allele assessment. PCR, sequencing. | inbred w/CC8 (58) | both | 6wks | 2013 |
|
|
immune cell quantification | Regulatory T cells (Treg), thymus, spleen. | inbred (33) | m | 5-6wks | 2007 |
|
|
ventilator
with methacholine |
Airway resistance. Baseline vs. methacholine-challenged (several doses). | inbred (37) | both | 9-12wks | 2010 |
|
|
plethysmography
with methacholine |
Lung, respiratory function. Baseline vs. methacholine-challenged (several doses). | inbred (29) | both | 9-12wks | 2010 |
|
|
ventilator
with methacholine |
Lung, respiratory function. Anesthetized forced oscillation. Baseline vs. methacholine-challenged (several doses). | inbred (29) | both | 9-12wks | 2010 |
|
|
metabolite quantification | Vitamin D concentration (serum). | inbred (18) | m | 11wks | 2011 |
|
|
histopathology | Lung adenoma frequency and severity at 20mo. Tumor incidence, cancer, aging. | inbred (28) | both | 87wks | 2011 |
|
|
intake monitoring
with sucrose |
Food, caloric, water intake. Baseline and with sucrose (several concentrations). 24h test. | inbred (12) | m | 13-17wks | 2006 |
|
|
study archive | Spontaneous diseases. | inbred | both | 2013 | |
|
|
genotyping | SNP profiling, 131,000+ genomic locations, 1-19,X. | inbred (89) | 2009 | ||
|
|
genotyping | SNP profiling, 470,000+ genomic locations, 1-19,X,Y,MT. | inbred (142) | m | 2014 | |
|
|
electroretinography | Photoreceptor measures: rod Awave, Bwave, cone Bwave. | inbred (17) | both | 10-13wks | 2008 |
|
|
organ dimensions | Eye diameter. | inbred (17) | both | 10-13wks | 2008 |
|
|
immune cell quantification | Natural killer T cells in peripheral blood, spleen, thymus. | inbred (38) | both | 8-10wks | 2011 |
|
|
urinalysis | Microalbumin, creatinine, ratio. | inbred w/CC7 (34) | m | 10wks | 2012 |
|
|
body weight | Body weight | inbred (14) | both | 9-12wks | 2003 |
|
|
bone dimensions | Craniofacial bone dimensions. | inbred (14) | both | 9-12wks | 2003 |
|
|
body weight | Body weight | inbred (14) | both | 25wks | 2009 |
|
|
intake monitoring | Food intake, water intake at 6mo. Light phase, dark phase, total. | inbred (14) | both | 25wks | 2009 |
|
|
monitoring system | Locomotor activity. Aging study. 24h test with 12h light and 12h dark phases. | inbred (14) | both | 25wks | 2009 |
|
|
tail cuff
with sodium chloride |
Heart rate and blood pressure. Sodium chloride (1% solution for 2wks) vs. control. | inbred (11) | both | 9-12wks | 2003 |
|
|
ophthalmoscopy | Retinal fundoscopic examination. | inbred w/CC7 (41) | both | 6-7wks | 2008 |
|
|
slit lamp | Eye morphology. Frequency rates of disorders. | inbred w/CC7 (41) | both | 6-7wks | 2008 |
|
|
histopathology | Kidney pathology at 20mo. | inbred (23) | both | 87wks | 2014 |
|
|
body weight | Body weight and growth curve from age 3wks to 10 wks, weighed weekly. | inbred (24) | both | 8wks | 2000 |
|
|
MHC haplotype tissue typing | Major histocompatibility complex (MHC) H2 haplotype. | inbred (56) | both | 2000 | |
|
|
colony observation | Reproductive performance. | inbred (33) | f | various | 1991 |
|
|
colony observation | Appearance, coat color | inbred (61) | both | 2006 | |
|
|
colony observation | Reproductive performance. | inbred (35) | f | various | 2009 |
|
|
ABR test | Auditory brainstem response. | inbred (7) | m | 10-13wks | 2010 |
|
|
echocardiography | Cardiovascular function and morphology. | inbred (7) | m | 10-13wks | 2010 |
|
|
complete blood count | Hematology. | inbred (16) | both | 12-16wks | 2002 |
|
|
urinalysis | Microalbumin, creatinine, ratio. Aging study, 6mo, 12mo, and 20mo. | inbred (30) | both | 52, 78, 104 wks | 2008 |
|
|
histopathology | Kidney pathology. Aging study, 6mo, 12mo, 20mo. | inbred (29) | m | 52, 78, 104 wks | 2013 |
|
|
body weight | Body weight | inbred (41) | both | 8-9wks | 2010 |
|
|
running wheel monitoring | Distance, duration, speed. | inbred (41) | both | 8-9wks | 2010 |
|
|
apoptosis assessment | Aging study, 6mo, 12mo, 20mo. | inbred (30) | both | 26, 52, 87 wks | 2008 |
|
|
chromosome instability assessment | Chromosome instability. Aging study, 6mo, 12mo, 20mo. | inbred (30) | both | 26, 52, 87 wks | 2008 |
|
|
nociception assay | Battery of tests for mechanical, chemical, thermal nociception. | inbred (12) | m | 6-18wks | 2002 |
|
|
monitoring system | Locomotor activity. Light and dark phases. | inbred (12) | m | 6-10wks | 2000 |
|
|
body weight
with high-fat diet |
High-fat diet for 8wks. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
|
DXA
with high-fat diet |
Body mass, fat mass, lean mass, bone mineral density and content after 8wks on high-fat diet. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
|
hormone quantification
with high-fat diet |
Insulin and leptin after 18wks on high-fat diet. Multiple readings per animal were averaged. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
|
metabolic panel
with high-fat diet |
Glucose (plasma). Baseline vs. high-fat diet (17wks). 4h fast. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
|
body weight
with high-fat diet |
Baseline vs. high-fat diet for 8wks. | inbred (44) | both | 15-19wks | 2000 |
|
|
histopathology
with high-fat diet |
Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
|
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
|
|
metabolic panel
with high-fat diet |
Alanine transaminase, bile salts (plasma) after 8wks on high-fat diet. 4h fast. | inbred (44) | both | 15-19wks | 2000 |
|
|
organ dimensions
with high-fat diet |
Gallbladder volume after 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
|
|
organ weights
with high-fat diet |
Liver weight after 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
|
|
histopathology
with high-fat diet |
Aortic lesion size histopathology. Baseline vs. high-fat diet (17wks). | inbred w/CC7 (43) | both | 7-9wks, 24-27wks | 2002 |
|
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL, triglycerides. Baseline vs. high-fat diet (17wks). 4h fast, plasma. | inbred w/CC7 (43) | both | 7-9wks, 24-27wks | 2002 |
|
|
lipid profile | Cholesterol, HDL, non-HDL, triglycerides. 4h fast, plasma. | inbred w/CC7 (43) | both | 10wks | 2002 |
|
|
coagulation test | Fibrinogen. | inbred w/CC7 (43) | both | 10wks | 2001 |
|
|
complete blood count | Hematology. | inbred w/CC7 (43) | both | 10wks | 2001 |
|
|
complete blood count | Hematology. Aging study, 6mo, 12mo, 18mo, 24mo. | inbred (30) | both | 26, 52, 78, 104 wks | 2007 |
|
|
complete blood count | Hematology. Aging study, 6mo, 12mo, 18mo, 24mo. | inbred (32) | both | 26, 52, 78, 104 wks | 2007 |
|
|
immune cell quantification | Aging study, 6mo, 12mo, 18mo, 24mo. | inbred (32) | both | 26, 52, 78, 104 wks | 2007 |
|
|
body weight
with exercise |
Exercise wheel group vs. control group. | inbred (12) | both | 8-15wks | 2010 |
|
|
microscopy
with exercise |
Examination of hippocampus dentate gyrus. Exercise wheel group vs. control group. | inbred (12) | both | 8-15wks | 2010 |
|
|
running wheel monitoring
with exercise |
Locomotor activity. Exercise wheel group vs. control group. Distance per day. | inbred (12) | both | 8-15wks | 2010 |
|
|
alcohol quantification
with high-fat diet and ethanol |
Alcohol concentration in blood and urine after 4 wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
|
histopathology
with high-fat diet and ethanol |
Liver histopathology, injury after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
|
lipid profile
with high-fat diet and ethanol |
Hepatic triglycerides after 4wk regimen of ethanol and high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
|
metabolic panel
with high-fat diet and ethanol |
Alanine transaminase (serum) after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
|
metabolite quantification
with high-fat diet and ethanol |
Homocysteine concentration after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
|
organ weights
with high-fat diet and ethanol |
Liver weight after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
|
RNA expression profiling
with high-fat diet and ethanol |
Liver gene expression after 4wk regimen of ethanol and high-fat diet. 24h fast. mRNA abundance relative to the control (high-fat only) group. | inbred (14) | m | 8-14wks | 2011 |
|
|
genotyping | SNP profiling, 80,000,000+ genomic locations. SNPs and indels. 1-19,X. | inbred (37) | both | 2017 | |
|
|
gait analysis | Aging study, 6mo, 18mo. | inbred (32) | both | 26, 52, 78, 104 wks | 2008 |
|
|
grip strength | Peak tension. 3 trials. Aging study, 6mo, 12mo, 18mo, 24mo. | inbred (32) | both | 26, 52, 78, 104 wks | 2008 |
|
|
study archive | Histopathology. Aging study. | inbred (28) | both | 2008 | |
|
|
tail cuff | Heart rate and blood pressure. Conscious mice. | inbred (14) | both | 9wks | 2004 |
|
|
biomarker quantification
with acetaminophen |
Liver cytochrome isoforms. Acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
histopathology
with acetaminophen |
Liver histopathology, necrosis after acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
metabolic panel
with acetaminophen |
Blood urea nitrogen, alanine transaminase, aspartate transaminase (serum), liver enzyme homeostasis. Acetaminophen (several doses) vs. control, several timepoints post-Rx. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
metabolite quantification
with acetaminophen |
Liver protein homeostasis. Acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
organ weights
with acetaminophen |
Liver weight after acetaminophen (several doses) vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
|
biomarker quantification | Fibronectin. | inbred (25) | both | 9wks | 2007 |
|
|
body weight | Body weight | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
bottle choice test | Various salt solutions (several concentrations) vs. water. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
metabolic panel | Ionized and total blood calcium, blood pH. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
monitoring system | Bleeding time to collect approx 30 µL. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
|
elevated plus maze | Exploratory and anxiety-related behaviors. 5 min test. | inbred (16) | m | 6-8wks | 1993 |
|
|
hormone quantification | Corticosterone levels (plasma). Baseline vs. after stress (30 min in restraining cage). | inbred (16) | m | 6-8wks | 1993 |
|
|
monitoring system | Novelty-induced fear test. Eating inhibition due to novelty of environment. 10 min test. | inbred (16) | m | 6-8wks | 1993 |
|
|
open field test | Locomotor activity under dim lights vs. bright lights. 5 min test. | inbred (16) | m | 6-8wks | 1993 |
|
|
genotyping | SNP profiling, 132,000+ genomic locations, 1-19,X | HMDP (248) | both | 2018 | |
|
|
body weight | Body weight | inbred (21) | both | 6-8wks | 2009 |
|
|
bone dimensions | Craniofacial bone dimensions. | inbred (21) | both | 6-8wks | 2009 |
|
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | inbred w/CC7 (40) | both | 5-6wks | 2002 |
|
|
body weight | Body weight | inbred w/CC7 (40) | both | 5-6wks | 2002 |
|
|
ECG | Heart rate and wave intervals. Conscious. Aging study, 6mo, 12mo, 20mo. | inbred (29) | both | 26, 52, 87 wks | 2008 |
|
|
gait analysis | Aging study, 6mo, 12mo, 18mo. | inbred (31) | both | 26, 52, 78 wks | 2010 |
|
|
body weight | Aging study, 6mo, 12mo, and 18mo. | inbred (33) | both | 26, 52, 78 wks | 2007 |
|
|
hormone quantification | Insulin-like growth factor 1 (serum). Aging study, 6mo, 12mo, and 18mo. | inbred (33) | both | 26, 52, 78 wks | 2007 |
|
|
colony observation | Life span study. Survival curves. Aging study. | inbred (31) | both | max lifespan | 2007 |
|
|
lipid profile | Cholesterol (HDL). Aging study, 6mo, 12mo, 18mo. 4h fast, plasma. | inbred (32) | both | 26, 52, 78 wks | 2008 |
|
|
metabolic panel | Clinical blood chemistry. Aging study, 6mo, 12mo, 18mo. | inbred (32) | both | 26, 52, 78 wks | 2008 |
|
|
colony observation | Observed age at vaginal opening (patency). Aging study. | inbred (33) | f | 2-9wks | 2009 |