Threadgill2 animal documentation

Drug study: Acetaminophen pharmakokinetics and drug-induced liver injury in males of 5 inbred strains of mice   (2005)

Threadgill DW, Harrill A
With: Ross PK, Rusyn I




Threadgill1 Animal Documentation

Acclimation & testing periods

Vendor Male mice were obtained from The Jackson Laboratory (JAX®, Bar Harbor, ME)
Ages
6-8 wks old at the time of testing
Feed
Irradiated NTP-2000 wafer chow (Zeigler Brothers, Inc., East Berlin, PA)
Water
Ad-libitum
Temperature
69-75°F (20.5-23.9°C)
Humidity
35-65%
Housing
Singly housed in polycarbonate cages
Bedding
Sani-Chips, irradiated hardwood bedding (P.J. Murphy Forest Products Corp., Montville, NJ)
Photoperiod
12h:12h light-dark cycle
Regulatory compliance
Care of mice followed institutional guidelines under a protocol approved by the Institutional Animal Care and Use Committee at the University of North Carolina at Chapel Hill.