MPD: Threadgill2: animal documentation

Threadgill2 animal documentation

Drug study: Acetaminophen pharmakokinetics and drug-induced liver injury in males of 5 inbred strains of mice (2005)

Threadgill DW, Harrill A
With: Ross PK, Rusyn I

Threadgill1 Animal Documentation

Acclimation & testing periods

Vendor Male mice were obtained from The Jackson Laboratory (JAX®, Bar Harbor, ME)

Ages

6-8 wks old at the time of testing

Feed

Irradiated NTP-2000 wafer chow (Zeigler Brothers, Inc., East Berlin, PA)

Water

Ad-libitum

Temperature

69-75°F (20.5-23.9°C)

Humidity

35-65%

Housing

Singly housed in polycarbonate cages

Bedding

Sani-Chips, irradiated hardwood bedding (P.J. Murphy Forest Products Corp., Montville, NJ)

Photoperiod

12h:12h light-dark cycle

Regulatory compliance

Care of mice followed institutional guidelines under a protocol approved by the Institutional Animal Care and Use Committee at the University of North Carolina at Chapel Hill.

Vendor	Male mice were obtained from The Jackson Laboratory (JAX®, Bar Harbor, ME)
Ages	6-8 wks old at the time of testing
Feed	Irradiated NTP-2000 wafer chow (Zeigler Brothers, Inc., East Berlin, PA)
Water	Ad-libitum
Temperature	69-75°F (20.5-23.9°C)
Humidity	35-65%
Housing	Singly housed in polycarbonate cages
Bedding	Sani-Chips, irradiated hardwood bedding (P.J. Murphy Forest Products Corp., Montville, NJ)
Photoperiod	12h:12h light-dark cycle
Regulatory compliance	Care of mice followed institutional guidelines under a protocol approved by the Institutional Animal Care and Use Committee at the University of North Carolina at Chapel Hill.