Acclimation & testing periods
Vendor14 inbred strains of male mice were obtained from the Jackson Laboratory (JAX®, Bar Harbor, ME) at 5-6 wks of age Ages7 wks of age at the start of the experiment FeedNTP-2000 wafer diet (Zeigler Brothers, Inc., Gardners, PA) WaterWater was give ad libitum Housingpolycarbonate cages Room temperature20.6-23.9°C ambient temperature Humidity35-65% BeddingSani-Chips irradiated hardwood bedding (P.J. Murphy Forest Products Corp., Montville, NJ) Photoperiod12h:12h light-dark cycle Regulatory complianceCare of mice followed institutional guidelines under a protocol approved by the Institutional Animal Care and Use Committee at the University of North Carolina at Chapel Hill.