Graham3 animal documentation

Baseline T cell immune phenotypes in males of 104 F1 hybrid lines of Collaborative Cross strains of mice (CC RIX) predict virologic and disease control upon SARS-CoV infection   (2021)

Graham JB, Baric RS, Lund JM
With: Swarts JL, Leist SR, Schäfer A, Menachery VD, Gralinski LE, Jeng S, Miller DR, Mooney MA, McWeeney SK, Ferris MT, Pardo-Manuel de Villena F, Heise MT




Animal Documentation

Source of Mice: Collaborative Cross mice were obtained from the Systems Genetics Core Facility at the University of North Carolina-Chapel Hill (UNC)

Age (wks): 8-10 wks at testing

Breeding: F1 hybrids were bred at UNC

Test Facility: University of Washington, housed directly in a BSL-2+ laboratory within an SPF barrier facility

Care and Use Statement: Experiments were approved by the UW or UNC IACUC. The Office of Laboratory Animal Welfare of NIH approved UNC (#A3410-01) and the UW (#A3464-01), and this study was carried out in strict compliance with the PHS Policy on Humane Care and Use of Lab Mice