Ferris1 supplemental data

Host response to Influenza A (H1N1) in 8 inbred founder strains and 150+ emerging lines (pre-CC) of the Collaborative Cross   (2012)

Ferris MT, Bottomly D, McWeeney SK, Heise MT
With: Aicher LD, Rosenzweig E, Whitmore A, Aylor DL, Haagmans BL, Gralinski LE, Bradel-Tretheway BG, Bryan JT, Threadgill DW, de Villena FP, Baric RS, Katze MG


Ferris1_suppdata

Supplementary Data (all Ferris1 data supplied in this file, including mock treatments and males)

var_name MPD description Units
bw_preD7 body weight 7 days before infection g
bw_preD6 body weight 6 days before infection g
bw_preD5 body weight 5 days before infection g
bw_preD4 body weight 4 days before infection g
bw_preD3 body weight 3 days before infection g
bw_preD2 body weight 2 days before infection g
bw_preD1 body weight 1 day before infection g
bw_D0 body weight pre-infection (day 0) g
bw_D1 body weight day 1 post-infection g
bw_D2 body weight day 2 post-infection g
bw_D3 body weight day 3 post-infection g
bw_D4 body weight day 4 post-infection g
bw_change percent change in body weight, day 4 post-infection %
clinical_score clinical score, day 4 post-infection (score 0-4) score
susceptibility_index susceptibility to viral infection index (0=susceptible; 1= resistant) designation
hemorrage virus-induced hemorrhage, day 4 post-infection (score 0-2) score
gross_edema virus-induced gross edema, day 4 post-infection (score 0-3) score
titer viral replication log titer, day 4 post-infection (lung) score
IHC immunohistochemical (IHC) detection of virus antigen, day 4 post-infection (score 0-5) score
airway_inflam virus-induced airway inflammation, day 4 post-infection (score 0-3) score
airway_neut virus-induced airway neutrophils, day 4 post-infection (score 0-3) score
airway_mono virus-induced airway monocytes, day 4 post-infection (score 0-3) score
airway_damage virus-induced airway damage, day 4 post-infection (score 0-3) score
vascular_inflam virus-induced vascular inflammation (lung), day 4 post-infection (score 0-3) score
vascular_neut virus-induced vascular neutrophils (lung), day 4 post-infection (score 0-3) score
vascular_mono virus-induced vascular monocytes (lung), day 4 post-infection (score 0-3) score
alveolar_inflam virus-induced alveoar inflammation, day 4 post-infection (score 0-3) score
alveolar_damage virus-induced alveolar damage, day 4 post-infection (score 0-3) score
pulmonary_edema virus-induced pulmonary edema, day 4 post-infection (score 0-3) score
fibrin virus-induced fibrin deposition, day 4 post-infection (score 0-3) score

Download supplementary data: Ferris1_suppdata.xlxs