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      • abnormal tumor necrosis factor level
      • abnormal circulating cytokine level

    • abnormal circulating tumor necrosis factor level   MP:0008552   (1)
    Definition: anomaly in the amount in the blood of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium [ISBN:0-8153-1691-7, MESH:D12.644.276.374.500.800];   [MGI annotations / genotypes]
      (No descendants that are mapped to MPD data)



    VT:0008552 (blood tumor necrosis factor amount) is numbered similarly to MP:0008552 but is over in the VT ontology (semantics may or may not be similar).

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