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      • abnormal glomerular mesangium morphology

    • abnormal mesangial cell morphology   MP:0005327   (0)
    Definition: any structural anomaly of the modified smooth muscle cells that are interposed between endothelial cells and the basement membrane in the central or stalk region of the capillary tuft of the renal glomerulus, which regulate blood flow by their contractile activity, and secrete extracellular matrix, prostaglandins, and cytokines; mesangial cells also have phagocytic activity, removing proteins and other molecules trapped in the glomerular basement membrane or filtration barrier [ISBN:0-683-40008-8, MGI:anna];   [MGI annotations / genotypes]
      (No descendants that are mapped to MPD data)



    VT:0005327 (mesangial cell morphology trait) is numbered similarly to MP:0005327 but is over in the VT ontology (semantics may or may not be similar).

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