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      • abnormal professional antigen presenting cell physiology
      • abnormal lymphocyte physiology

• abnormal B cell physiology   MP:0002459   (30)
Definition: any functional anomaly of lymphocytes that expresses membrane-bound antibody, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens [MGI:csmith, MGI:cwg];   [MGI annotations / genotypes]
• abnormal immunoglobulin level     (30)
          • abnormal IgA level     (6)
          • abnormal IgE level     (1)
          • abnormal IgG level     (17)
          • abnormal IgM level     (6)




VT:0002459 (B cell physiology trait) is numbered similarly to MP:0002459 but is over in the VT ontology (semantics may or may not be similar).

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