Phenotype measures set:   Wiltshire4   Tcells_BEZ

ID, description, units MPD:52407   Tcells_BEZ   T cells, percent viability   [%]
BEZ235 study
Measures • dose [µM]:    • control    • 0.046    • 0.137    • 1.235    • 11.1    • 100
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Comparisoncontrol group vs. multiple treatment / dosage groups
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Wiltshire4 - T cells, percent viability





  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 5 934.7393 186.9479 9.5598 < 0.0001
strain 33 5460.461 165.4685 8.4614 < 0.0001
dose:strain 165 6093.5319 36.9305 1.8885 < 0.0001
Residuals 594 11616.0369 19.5556

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelStrains
tested
SexAge
Wiltshire4 52407 immune cell quantification BEZ235 T cells, percent viability   [%]   control   Tcells_BEZ_ctrl inbred w/CC7 34 m 10wks
Wiltshire4 52408 immune cell quantification BEZ235 T cells, percent viability   [%]   dose: 0.046 µM   Tcells_BEZ_A inbred w/CC7 34 m 10wks
Wiltshire4 52409 immune cell quantification BEZ235 T cells, percent viability   [%]   dose: 0.137 µM   Tcells_BEZ_B inbred w/CC7 34 m 10wks
Wiltshire4 52410 immune cell quantification BEZ235 T cells, percent viability   [%]   dose: 1.235 µM   Tcells_BEZ_C inbred w/CC7 34 m 10wks
Wiltshire4 52411 immune cell quantification BEZ235 T cells, percent viability   [%]   dose: 11.1 µM   Tcells_BEZ_D inbred w/CC7 34 m 10wks
Wiltshire4 52412 immune cell quantification BEZ235 T cells, percent viability   [%]   dose: 100 µM   Tcells_BEZ_E inbred w/CC7 34 m 10wks