MPD: Project measures / variables set: Maurer1 bwchg

Project measures / variables set: Maurer1 bwchg

ID, description, units	MPD:33266 bwchg fold change in body weight over testing period [ratio] atenolol, isoproterenol study
Measures	• control • atenolol 10mg • isoprot 1mg • isoprot 10mg
Data set, strains	Maurer1 inbred 23 strains sex: m age: 7-13wks
Procedure	body weight
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0001259 body mass VT:0010487 response to xenobiotic stimulus trait MP:0001259 abnormal body weight MP:0008872 abnormal physiological response to xenobiotic

SIDE-BY-SIDE STRAIN CURVES

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	3	0.5095	0.1698	46.4698	< 0.0001
strain	22	1.6498	0.075	20.5209	< 0.0001
group:strain	66	0.6487	0.0098	2.6896	< 0.0001
Residuals	831	3.0369	0.0037

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

	Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
	Maurer1	33266	body weight	atenolol, isoproterenol	fold change in body weight over testing period [ratio] control bwchg_ctrl	inbred	23	m	7-13wks
	Maurer1	33267	body weight	atenolol, isoproterenol	fold change in body weight over testing period [ratio] atenolol 10mg bwchg_at	inbred	23	m	7-13wks
	Maurer1	33268	body weight	atenolol, isoproterenol	fold change in body weight over testing period [ratio] isoprot 1mg bwchg_iso1	inbred	23	m	7-13wks
	Maurer1	33269	body weight	atenolol, isoproterenol	fold change in body weight over testing period [ratio] isoprot 10mg bwchg_iso10	inbred	23	m	7-13wks