Project measure / variable:   Paigen2   TG_fat17

ID, description, units MPD:9922   TG_fat17   triglycerides (plasma, 4h fast)   [mg/dL]  after 17wks on diet  
high-fat diet study
Data set, strains Paigen2   inbred w/CC7   41 strains     sex: both     age: 7-9wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen2 - triglycerides (plasma, 4h fast) after 17wks on diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains36 strains
Mean of the strain means96.1   mg/dL 90.4   mg/dL
Median of the strain means67.8   mg/dL 69.9   mg/dL
SD of the strain means± 86.6 ± 51.1
Coefficient of variation (CV)0.901 0.566
Min–max range of strain means35.2   –   534   mg/dL 36.3   –   249   mg/dL
Mean sample size per strain8.1   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1464.9855 1464.9855 0.5135 0.474
strain 34 1709913.0556 50291.5605 17.629 < 0.0001
sex:strain 34 346681.1711 10196.505 3.5742 < 0.0001
Residuals 497 1417826.5021 2852.7696


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 42.4 13.9   5 6.23 0.328 28.0, 63.0 -0.62
129S1/SvImJ m 62.0 9.83   8 3.47 0.159 44.0, 75.0 -0.55
A/J f 74.9 10.2   10 3.24 0.137 57.0, 95.0 -0.25
A/J m 69.9 21.3   8 7.53 0.305 37.0, 104.0 -0.4
AKR/J f 111.0 145.0   12 42.0 1.31 46.0, 571.0 0.17
BALB/cByJ f 36.3 8.82   11 2.66 0.243 25.0, 59.0 -0.69
BALB/cByJ m 64.8 24.0   8 8.49 0.371 35.0, 89.0 -0.5
BTBR T+ Itpr3tf/J f 54.1 8.25   8 2.92 0.152 43.0, 68.0 -0.49
BTBR T+ Itpr3tf/J m 51.1 5.3   7 2.01 0.104 42.0, 56.0 -0.77
BUB/BnJ f 79.2 40.0   9 13.3 0.505 20.0, 165.0 -0.2
BUB/BnJ m 66.4 39.9   5 17.9 0.601 26.0, 114.0 -0.47
C3H/HeJ f 56.3 10.8   10 3.41 0.191 40.0, 69.0 -0.46
C3H/HeJ m 55.0 15.4   8 5.43 0.279 32.0, 83.0 -0.69
C57BL/10J f 35.9 12.5   7 4.74 0.35 25.0, 55.0 -0.7
C57BL/10J m 36.3 9.46   10 2.99 0.261 23.0, 49.0 -1.06
C57BL/6J f 43.2 3.77   10 1.19 0.0872 39.0, 50.0 -0.61
C57BL/6J m 61.2 32.4   10 10.2 0.53 31.0, 146.0 -0.57
C57BLKS/J f 35.2 14.9   4 7.43 0.422 22.0, 53.0 -0.7
C57BLKS/J m 56.2 16.6   5 7.45 0.296 41.0, 77.0 -0.67
C57BR/cdJ f 62.5 7.74   10 2.45 0.124 54.0, 76.0 -0.39
C57BR/cdJ m 58.8 15.5   10 4.9 0.264 40.0, 90.0 -0.62
C57L/J f 47.1 11.7   8 4.12 0.247 29.0, 61.0 -0.57
C57L/J m 54.8 20.1   10 6.35 0.366 29.0, 96.0 -0.7
C58/J f 63.0 20.9   5 9.36 0.332 39.0, 94.0 -0.38
C58/J m 88.7 44.5   7 16.8 0.501 62.0, 187.0 -0.03
CAST/EiJ f 186.0 97.0   8 34.3 0.522 58.0, 347.0 1.04
CAST/EiJ m 249.0 148.0   5 66.2 0.594 167.0, 513.0 3.1
CBA/J f 59.6 12.2   8 4.3 0.204 49.0, 84.0 -0.42
CBA/J m 81.6 22.1   8 7.83 0.271 49.0, 124.0 -0.17
CZECHII/EiJ f 81.1 57.3   10 18.1 0.707 45.0, 219.0 -0.17
CZECHII/EiJ m 91.1 55.2   8 19.5 0.606 54.0, 219.0 0.01
DBA/1J f 55.2 11.0   4 5.48 0.198 39.0, 63.0 -0.47
DBA/1J m 59.7 29.2   6 11.9 0.49 32.0, 102.0 -0.6
DBA/2J f 123.0 37.3   9 12.4 0.304 54.0, 161.0 0.31
DBA/2J m 136.0 11.6   9 3.86 0.0852 122.0, 157.0 0.89
FVB/NJ f 100.0 24.7   8 8.73 0.246 65.0, 127.0 0.04
FVB/NJ m 82.3 21.2   6 8.66 0.257 54.0, 107.0 -0.16
I/LnJ f 46.8 25.8   5 11.6 0.552 24.0, 89.0 -0.57
JF1/MsJ f 124.0 31.4   10 9.93 0.253 82.0, 189.0 0.32
JF1/MsJ m 123.0 38.2   7 14.5 0.311 59.0, 184.0 0.64
KK/HlJ f 168.0 71.9   7 27.2 0.427 124.0, 326.0 0.83
LP/J f 68.5 14.6   10 4.62 0.213 36.0, 86.0 -0.32
LP/J m 75.8 11.6   11 3.49 0.153 63.0, 99.0 -0.28
MA/MyJ f 81.3 24.5   10 7.76 0.302 48.0, 132.0 -0.17
MA/MyJ m 63.2 19.1   10 6.04 0.302 46.0, 100.0 -0.53
MOLF/EiJ f 177.0 80.1   7 30.3 0.453 94.0, 328.0 0.93
MOLF/EiJ m 199.0 107.0   9 35.5 0.534 72.0, 393.0 2.13
MSM/MsJ f 263.0 66.1   8 23.4 0.251 167.0, 355.0 1.93
MSM/MsJ m 198.0 65.9   11 19.9 0.332 133.0, 339.0 2.11
NOD/ShiLtJ f 48.5 8.53   6 3.48 0.176 40.0, 64.0 -0.55
NOD/ShiLtJ m 159.0 229.0   6 93.6 1.44 50.0, 626.0 1.34
NON/ShiLtJ f 66.5 13.4   10 4.23 0.201 45.0, 87.0 -0.34
NON/ShiLtJ m 105.0 37.5   12 10.8 0.358 75.0, 185.0 0.29
NZB/BlNJ f 80.7 29.2   10 9.23 0.362 32.0, 131.0 -0.18
NZB/BlNJ m 69.9 22.6   9 7.52 0.323 35.0, 113.0 -0.4
NZW/LacJ f 67.4 19.2   9 6.39 0.284 45.0, 100.0 -0.33
NZW/LacJ m 51.1 8.32   8 2.94 0.163 39.0, 62.0 -0.77
PERA/EiJ f 82.9 11.8   9 3.95 0.143 64.0, 100.0 -0.15
PERA/EiJ m 61.7 13.2   7 4.99 0.214 42.0, 76.0 -0.56
PL/J f 173.0 126.0   10 39.9 0.729 46.0, 486.0 0.89
PWK/PhJ m 71.9 7.45   7 2.82 0.104 64.0, 84.0 -0.36
RF/J f 141.0 100.0   7 37.8 0.709 76.0, 360.0 0.52
RIIIS/J f 61.6 10.8   5 4.83 0.175 49.0, 78.0 -0.4
RIIIS/J m 62.5 12.4   8 4.4 0.199 44.0, 78.0 -0.55
SEA/GnJ f 57.0 11.6   9 3.87 0.204 38.0, 73.0 -0.45
SEA/GnJ m 71.7 19.9   7 7.52 0.277 58.0, 114.0 -0.37
SJL/J f 54.0 15.9   8 5.62 0.294 35.0, 87.0 -0.49
SJL/J m 97.5 62.8   12 18.1 0.645 58.0, 274.0 0.14
SM/J f 68.2 15.7   8 5.55 0.23 40.0, 89.0 -0.32
SM/J m 90.6 44.5   9 14.8 0.491 51.0, 156.0 0.0
SPRET/EiJ f 534.0 409.0   4 205.0 0.765 216.0, 1134.0 5.05
SPRET/EiJ m 209.0 39.6   5 17.7 0.189 150.0, 260.0 2.32
SWR/J f 53.2 9.53   8 3.37 0.179 41.0, 70.0 -0.5
SWR/J m 56.8 26.3   6 10.7 0.463 37.0, 104.0 -0.66
WSB/EiJ f 82.6 33.7   8 11.9 0.408 55.0, 160.0 -0.16
WSB/EiJ m 62.1 7.03   9 2.34 0.113 51.0, 77.0 -0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 42.4 23.8863 89.3305 0.0
129S1/SvImJ m 62.0 18.8838 99.1018 24.8982
A/J f 74.9 16.8901 108.0849 41.7151
A/J m 69.875 18.8838 106.9768 32.7732
BALB/cByJ f 36.2727 16.1041 67.9133 4.6322
BALB/cByJ m 64.75 18.8838 101.8518 27.6482
BTBR T+ Itpr3tf/J f 54.125 18.8838 91.2268 17.0232
BTBR T+ Itpr3tf/J m 51.1429 20.1876 90.8064 11.4793
BUB/BnJ f 79.2222 17.8038 114.2022 44.2423
BUB/BnJ m 66.4 23.8863 113.3305 19.4695
C3H/HeJ f 56.3 16.8901 89.4849 23.1151
C3H/HeJ m 55.0 18.8838 92.1018 17.8982
C57BL/10J f 35.8571 20.1876 75.5207 0.0
C57BL/10J m 36.3 16.8901 69.4849 3.1151
C57BL/6J f 43.2 16.8901 76.3849 10.0151
C57BL/6J m 61.2 16.8901 94.3849 28.0151
C57BLKS/J f 35.25 26.7057 87.7199 0.0
C57BLKS/J m 56.2 23.8863 103.1305 9.2695
C57BR/cdJ f 62.5 16.8901 95.6849 29.3151
C57BR/cdJ m 58.8 16.8901 91.9849 25.6151
C57L/J f 47.125 18.8838 84.2268 10.0232
C57L/J m 54.8 16.8901 87.9849 21.6151
C58/J f 63.0 23.8863 109.9305 16.0695
C58/J m 88.7143 20.1876 128.3778 49.0508
CAST/EiJ f 185.625 18.8838 222.7268 148.5232
CAST/EiJ m 249.2 23.8863 296.1305 202.2695
CBA/J f 59.625 18.8838 96.7268 22.5232
CBA/J m 81.625 18.8838 118.7268 44.5232
CZECHII/EiJ f 81.1 16.8901 114.2849 47.9151
CZECHII/EiJ m 91.125 18.8838 128.2268 54.0232
DBA/1J f 55.25 26.7057 107.7199 2.7801
DBA/1J m 59.6667 21.8051 102.5082 16.8252
DBA/2J f 122.6667 17.8038 157.6466 87.6867
DBA/2J m 135.8889 17.8038 170.8688 100.9089
FVB/NJ f 100.5 18.8838 137.6018 63.3982
FVB/NJ m 82.3333 21.8051 125.1748 39.4918
JF1/MsJ f 124.3 16.8901 157.4849 91.1151
JF1/MsJ m 122.8571 20.1876 162.5207 83.1936
LP/J f 68.5 16.8901 101.6849 35.3151
LP/J m 75.8182 16.1041 107.4587 44.1776
MA/MyJ f 81.3 16.8901 114.4849 48.1151
MA/MyJ m 63.2 16.8901 96.3849 30.0151
MOLF/EiJ f 176.7143 20.1876 216.3778 137.0508
MOLF/EiJ m 199.4444 17.8038 234.4244 164.4645
MSM/MsJ f 263.25 18.8838 300.3518 226.1482
MSM/MsJ m 198.3636 16.1041 230.0042 166.7231
NOD/ShiLtJ f 48.5 21.8051 91.3415 5.6585
NOD/ShiLtJ m 158.8333 21.8051 201.6748 115.9918
NON/ShiLtJ f 66.5 16.8901 99.6849 33.3151
NON/ShiLtJ m 104.6667 15.4185 134.9602 74.3731
NZB/BlNJ f 80.7 16.8901 113.8849 47.5151
NZB/BlNJ m 69.8889 17.8038 104.8688 34.9089
NZW/LacJ f 67.4444 17.8038 102.4244 32.4645
NZW/LacJ m 51.125 18.8838 88.2268 14.0232
PERA/EiJ f 82.8889 17.8038 117.8688 47.9089
PERA/EiJ m 61.7143 20.1876 101.3778 22.0508
RIIIS/J f 61.6 23.8863 108.5305 14.6695
RIIIS/J m 62.5 18.8838 99.6018 25.3982
SEA/GnJ f 57.0 17.8038 91.9799 22.0201
SEA/GnJ m 71.7143 20.1876 111.3778 32.0508
SJL/J f 54.0 18.8838 91.1018 16.8982
SJL/J m 97.5 15.4185 127.7935 67.2065
SM/J f 68.25 18.8838 105.3518 31.1482
SM/J m 90.5556 17.8038 125.5355 55.5756
SPRET/EiJ f 534.5 26.7057 586.9699 482.0301
SPRET/EiJ m 209.4 23.8863 256.3305 162.4695
SWR/J f 53.25 18.8838 90.3518 16.1482
SWR/J m 56.8333 21.8051 99.6748 13.9918
WSB/EiJ f 82.625 18.8838 119.7268 45.5232
WSB/EiJ m 62.1111 17.8038 97.0911 27.1312


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 52.2 15.2246 82.1125 22.2875
A/J both 72.3875 12.6676 97.2762 47.4988
BALB/cByJ both 50.5114 12.4091 74.892 26.1307
BTBR T+ Itpr3tf/J both 52.6339 13.8215 79.7897 25.4782
BUB/BnJ both 72.8111 14.8957 102.0774 43.5448
C3H/HeJ both 55.65 12.6676 80.5387 30.7613
C57BL/10J both 36.0786 13.1607 61.936 10.2211
C57BL/6J both 52.2 11.9431 75.6653 28.7347
C57BLKS/J both 45.725 17.9147 80.9229 10.5271
C57BR/cdJ both 60.65 11.9431 84.1153 37.1847
C57L/J both 50.9625 12.6676 75.8512 26.0738
C58/J both 75.8571 15.6372 106.5804 45.1339
CAST/EiJ both 217.4125 15.2246 247.325 187.5
CBA/J both 70.625 13.3528 96.86 44.39
CZECHII/EiJ both 86.1125 12.6676 111.0012 61.2238
DBA/1J both 57.4583 17.2384 91.3275 23.5891
DBA/2J both 129.2778 12.5892 154.0123 104.5432
FVB/NJ both 91.4167 14.4227 119.7537 63.0797
JF1/MsJ both 123.5786 13.1607 149.436 97.7211
LP/J both 72.1591 11.6685 95.0848 49.2333
MA/MyJ both 72.25 11.9431 95.7153 48.7847
MOLF/EiJ both 188.0794 13.4584 214.5217 161.637
MSM/MsJ both 230.8068 12.4091 255.1875 206.4261
NOD/ShiLtJ both 103.6667 15.4185 133.9602 73.3731
NON/ShiLtJ both 85.5833 11.4347 108.0496 63.1171
NZB/BlNJ both 75.2944 12.2704 99.4027 51.1862
NZW/LacJ both 59.2847 12.9766 84.7805 33.7889
PERA/EiJ both 72.3016 13.4584 98.7439 45.8592
RIIIS/J both 62.05 15.2246 91.9625 32.1375
SEA/GnJ both 64.3571 13.4584 90.7995 37.9148
SJL/J both 75.75 12.1894 99.6991 51.8009
SM/J both 79.4028 12.9766 104.8986 53.907
SPRET/EiJ both 371.95 17.9147 407.1479 336.7521
SWR/J both 55.0417 14.4227 83.3787 26.7047
WSB/EiJ both 72.3681 12.9766 97.8639 46.8723




  GWAS USING LINEAR MIXED MODELS