Project measure / variable:   Brown1   activity_LD


  STRAIN COMPARISON PLOT
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Brown1 - total activity, line crosses plus rearing, 5 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means140   n 143   n
Median of the strain means128   n 136   n
SD of the strain means± 62.6 ± 65.3
Coefficient of variation (CV)0.447 0.456
Min–max range of strain means37.8   –   241   n 28.3   –   232   n
Mean sample size per strain12.8   mice 13.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 341.1697 341.1697 0.1849 0.6674
strain 13 1359946.3146 104611.255 56.7052 < 0.0001
sex:strain 13 19579.6692 1506.1284 0.8164 0.6427
Residuals 347 640154.6438 1844.8261


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 63.9 30.0   12 8.67 0.47 28.0, 101.0 -1.22
129S1/SvImJ m 47.3 41.0   12 11.8 0.866 9.0, 123.0 -1.47
A/J f 37.8 33.1   12 9.55 0.874 4.0, 99.0 -1.64
A/J m 28.3 21.5   20 4.81 0.76 1.0, 89.0 -1.76
AKR/J f 130.0 34.4   11 10.4 0.265 68.0, 177.0 -0.16
AKR/J m 116.0 20.2   19 4.63 0.174 72.0, 156.0 -0.41
BALB/cByJ f 91.9 45.4   22 9.68 0.494 24.0, 264.0 -0.77
BALB/cByJ m 107.0 59.8   12 17.3 0.561 16.0, 217.0 -0.55
BALB/cJ f 89.6 38.4   14 10.3 0.428 46.0, 186.0 -0.81
BALB/cJ m 90.0 52.0   12 15.0 0.578 13.0, 187.0 -0.81
C3H/HeJ f 124.0 43.8   19 10.1 0.352 52.0, 215.0 -0.26
C3H/HeJ m 125.0 50.9   18 12.0 0.406 34.0, 226.0 -0.28
C57BL/6J f 225.0 43.6   12 12.6 0.194 135.0, 312.0 1.35
C57BL/6J m 216.0 47.0   13 13.0 0.218 141.0, 299.0 1.12
CAST/EiJ f 215.0 42.8   9 14.3 0.199 139.0, 273.0 1.2
CAST/EiJ m 202.0 38.6   12 11.2 0.191 121.0, 260.0 0.9
DBA/2J f 125.0 24.0   14 6.4 0.192 59.0, 159.0 -0.24
DBA/2J m 148.0 40.8   13 11.3 0.277 70.0, 230.0 0.08
FVB/NJ f 241.0 54.8   12 15.8 0.227 169.0, 389.0 1.61
FVB/NJ m 232.0 29.8   12 8.6 0.128 189.0, 284.0 1.36
MOLF/EiJ f 166.0 49.7   12 14.3 0.3 88.0, 237.0 0.41
MOLF/EiJ m 184.0 44.8   11 13.5 0.244 109.0, 260.0 0.63
SJL/J f 155.0 53.9   13 14.9 0.347 83.0, 232.0 0.24
SJL/J m 184.0 64.4   12 18.6 0.349 62.0, 280.0 0.63
SM/J f 200.0 53.4   10 16.9 0.268 107.0, 281.0 0.96
SM/J m 221.0 60.3   11 18.2 0.273 130.0, 297.0 1.19
SPRET/EiJ f 98.3 34.8   13 9.65 0.354 43.0, 169.0 -0.67
SPRET/EiJ m 102.0 27.0   13 7.5 0.265 53.0, 139.0 -0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 63.9167 12.399 88.3033 39.53
129S1/SvImJ m 47.3333 12.399 71.72 22.9467
A/J f 37.8333 12.399 62.22 13.4467
A/J m 28.3 9.6042 47.1898 9.4102
AKR/J f 129.9091 12.9503 155.3801 104.438
AKR/J m 116.2105 9.8537 135.5911 96.83
BALB/cByJ f 91.8636 9.1573 109.8744 73.8529
BALB/cByJ m 106.5833 12.399 130.97 82.1967
BALB/cJ f 89.6429 11.4793 112.2205 67.0652
BALB/cJ m 90.0 12.399 114.3867 65.6133
C3H/HeJ f 124.4737 9.8537 143.8542 105.0931
C3H/HeJ m 125.1111 10.1238 145.0227 105.1995
C57BL/6J f 224.75 12.399 249.1367 200.3633
C57BL/6J m 215.5385 11.9126 238.9684 192.1085
CAST/EiJ f 215.4444 14.3171 243.6038 187.2851
CAST/EiJ m 202.4167 12.399 226.8033 178.03
DBA/2J f 124.7143 11.4793 147.292 102.1366
DBA/2J m 147.6923 11.9126 171.1223 124.2623
FVB/NJ f 240.8333 12.399 265.22 216.4467
FVB/NJ m 232.1667 12.399 256.5533 207.78
MOLF/EiJ f 165.5833 12.399 189.97 141.1967
MOLF/EiJ m 183.9091 12.9503 209.3801 158.438
SJL/J f 155.4615 11.9126 178.8915 132.0316
SJL/J m 184.4167 12.399 208.8033 160.03
SM/J f 199.7 13.5824 226.4143 172.9857
SM/J m 220.6364 12.9503 246.1074 195.1653
SPRET/EiJ f 98.3077 11.9126 121.7377 74.8777
SPRET/EiJ m 102.0769 11.9126 125.5069 78.647


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 55.625 8.7674 72.869 38.381
A/J both 33.0667 7.8418 48.4902 17.6432
AKR/J both 123.0598 8.1365 139.0628 107.0568
BALB/cByJ both 99.2235 7.707 114.3818 84.0652
BALB/cJ both 89.8214 8.4485 106.4381 73.2047
C3H/HeJ both 124.7924 7.0638 138.6856 110.8992
C57BL/6J both 220.1442 8.5972 237.0533 203.2351
CAST/EiJ both 208.9306 9.4699 227.5562 190.3049
DBA/2J both 136.2033 8.2717 152.4722 119.9344
FVB/NJ both 236.5 8.7674 253.744 219.256
MOLF/EiJ both 174.7462 8.9645 192.3777 157.1147
SJL/J both 169.9391 8.5972 186.8482 153.03
SM/J both 210.1682 9.3834 228.6237 191.7127
SPRET/EiJ both 100.1923 8.4235 116.7598 83.6248




  GWAS USING LINEAR MIXED MODELS