Phenotype measure:   Brown1   activity_d1_OFT


  STRAIN COMPARISON PLOT
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Brown1 - total locomotor activity, line crosses plus rearing, 5 min test, day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means155   n 147   n
Median of the strain means165   n 159   n
SD of the strain means± 69.7 ± 59.6
Coefficient of variation (CV)0.449 0.405
Min–max range of strain means47.4   –   259   n 32.7   –   224   n
Mean sample size per strain12.5   mice 11.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 934.7716 934.7716 0.4819 0.4881
strain 13 1287149.9753 99011.5366 51.039 < 0.0001
sex:strain 13 51243.8169 3941.8321 2.032 0.018
Residuals 316 613014.3868 1939.9189


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 65.9 27.2   12 7.84 0.412 20.0, 106.0 -1.28
129S1/SvImJ m 68.2 35.0   12 10.1 0.513 6.0, 107.0 -1.32
A/J f 47.4 25.3   12 7.29 0.533 10.0, 90.0 -1.54
A/J m 32.7 24.1   12 6.95 0.737 2.0, 79.0 -1.92
AKR/J f 176.0 48.6   12 14.0 0.276 94.0, 253.0 0.3
AKR/J m 134.0 45.3   14 12.1 0.34 73.0, 252.0 -0.22
BALB/cByJ f 83.0 41.6   22 8.86 0.501 15.0, 180.0 -1.03
BALB/cByJ m 92.1 49.2   12 14.2 0.534 16.0, 199.0 -0.92
BALB/cJ f 86.0 41.1   14 11.0 0.478 22.0, 162.0 -0.99
BALB/cJ m 82.6 60.4   12 17.4 0.731 -1.08
C3H/HeJ f 154.0 42.5   14 11.4 0.276 104.0, 236.0 -0.01
C3H/HeJ m 153.0 58.3   12 16.8 0.38 70.0, 258.0 0.1
C57BL/6J f 200.0 41.1   12 11.9 0.206 139.0, 270.0 0.65
C57BL/6J m 175.0 40.1   13 11.1 0.228 106.0, 238.0 0.47
CAST/EiJ f 227.0 17.4   10 5.5 0.0766 195.0, 260.0 1.03
CAST/EiJ m 224.0 31.3   9 10.4 0.14 185.0, 272.0 1.29
DBA/2J f 132.0 46.1   14 12.3 0.35 11.0, 195.0 -0.33
DBA/2J m 165.0 29.4   12 8.48 0.178 122.0, 218.0 0.3
FVB/NJ f 243.0 58.5   12 16.9 0.24 184.0, 374.0 1.26
FVB/NJ m 203.0 26.9   12 7.75 0.132 144.0, 239.0 0.94
MOLF/EiJ f 259.0 50.0   12 14.4 0.193 169.0, 335.0 1.49
MOLF/EiJ m 220.0 37.8   11 11.4 0.172 171.0, 283.0 1.22
SJL/J f 213.0 29.9   13 8.3 0.14 154.0, 252.0 0.83
SJL/J m 177.0 38.2   12 11.0 0.216 101.0, 225.0 0.5
SM/J f 182.0 63.8   10 20.2 0.35 90.0, 273.0 0.39
SM/J m 201.0 57.8   12 16.7 0.288 89.0, 299.0 0.9
SPRET/EiJ f 102.0 62.5   13 17.3 0.611 10.0, 242.0 -0.76
SPRET/EiJ m 132.0 57.0   7 21.6 0.433 41.0, 211.0 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 65.9167 12.7146 90.9325 40.9008
129S1/SvImJ m 68.1667 12.7146 93.1825 43.1508
A/J f 47.4167 12.7146 72.4325 22.4008
A/J m 32.6667 12.7146 57.6825 7.6508
AKR/J f 175.9167 12.7146 200.9325 150.9008
AKR/J m 133.5714 11.7714 156.7316 110.4112
BALB/cByJ f 83.0455 9.3903 101.5209 64.57
BALB/cByJ m 92.0833 12.7146 117.0992 67.0675
BALB/cJ f 86.0 11.7714 109.1602 62.8398
BALB/cJ m 82.5833 12.7146 107.5992 57.5675
C3H/HeJ f 154.0714 11.7714 177.2316 130.9112
C3H/HeJ m 153.4167 12.7146 178.4325 128.4008
C57BL/6J f 199.5833 12.7146 224.5992 174.5675
C57BL/6J m 175.3846 12.2157 199.4191 151.3501
CAST/EiJ f 227.1 13.9281 254.5035 199.6965
CAST/EiJ m 223.8889 14.6815 252.7747 195.003
DBA/2J f 131.6429 11.7714 154.8031 108.4827
DBA/2J m 165.25 12.7146 190.2659 140.2341
FVB/NJ f 243.25 12.7146 268.2659 218.2341
FVB/NJ m 203.25 12.7146 228.2659 178.2341
MOLF/EiJ f 259.0 12.7146 284.0159 233.9841
MOLF/EiJ m 219.7273 13.2799 245.8555 193.599
SJL/J f 213.2308 12.2157 237.2653 189.1963
SJL/J m 176.75 12.7146 201.7659 151.7341
SM/J f 182.0 13.9281 209.4035 154.5965
SM/J m 200.75 12.7146 225.7659 175.7341
SPRET/EiJ f 102.3846 12.2157 126.4191 78.3501
SPRET/EiJ m 131.7143 16.6473 164.4678 98.9608


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 67.0417 8.9905 84.7306 49.3528
A/J both 40.0417 8.9905 57.7306 22.3528
AKR/J both 154.744 8.6635 171.7895 137.6986
BALB/cByJ both 87.5644 7.9031 103.1138 72.015
BALB/cJ both 84.2917 8.6635 101.3371 67.2462
C3H/HeJ both 153.744 8.6635 170.7895 136.6986
C57BL/6J both 187.484 8.816 204.8294 170.1386
CAST/EiJ both 225.4944 10.1185 245.4026 205.5862
DBA/2J both 148.4464 8.6635 165.4919 131.401
FVB/NJ both 223.25 8.9905 240.9389 205.5611
MOLF/EiJ both 239.3636 9.1926 257.4501 221.2772
SJL/J both 194.9904 8.816 212.3358 177.645
SM/J both 191.375 9.4294 209.9273 172.8227
SPRET/EiJ both 117.0495 10.3242 137.3623 96.7366




  GWAS USING LINEAR MIXED MODELS