Project measure / variable:   Willott1   PPI_20

ID, description, units MPD:9110   PPI_20   mean prepulse inhibition (PPI), 70dB   [ratio]  20 kHz  
Data set, strains Willott1   inbred w/CC7   40 strains     sex: both     age: 5-6wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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Willott1 - mean prepulse inhibition (PPI), 70dB 20 kHz



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains40 strains
Mean of the strain means0.543   ratio 0.569   ratio
Median of the strain means0.534   ratio 0.538   ratio
SD of the strain means± 0.185 ± 0.171
Coefficient of variation (CV)0.341 0.300
Min–max range of strain means0.258   –   0.932   ratio 0.303   –   1.00   ratio
Mean sample size per strain10.1   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1459 0.1459 3.2761 0.0707
strain 39 23.5031 0.6026 13.5281 < 0.0001
sex:strain 39 1.2106 0.031 0.6968 0.9194
Residuals 725 32.2971 0.0445


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.399 0.241   10 0.0761 0.602 0.109, 0.814 -0.78
129S1/SvImJ m 0.409 0.278   10 0.088 0.68 0.152, 1.03 -0.94
A/J f 0.605 0.207   10 0.0656 0.343 0.349, 0.87 0.33
A/J m 0.702 0.279   10 0.0883 0.397 0.231, 1.25 0.78
AKR/J f 0.365 0.132   10 0.0418 0.362 0.191, 0.676 -0.96
AKR/J m 0.303 0.127   10 0.0401 0.418 0.183, 0.599 -1.56
BALB/cJ f 0.547 0.163   18 0.0383 0.297 0.234, 0.895 0.02
BALB/cJ m 0.52 0.152   10 0.048 0.292 0.318, 0.838 -0.29
BTBR T+ Itpr3tf/J f 0.521 0.21   10 0.0665 0.404 0.249, 0.968 -0.12
BTBR T+ Itpr3tf/J m 0.535 0.245   10 0.0775 0.458 0.199, 1.04 -0.2
BUB/BnJ f 0.451 0.174   10 0.0552 0.387 0.202, 0.719 -0.5
BUB/BnJ m 0.486 0.25   10 0.079 0.514 0.253, 1.15 -0.49
C3H/HeJ f 0.713 0.186   10 0.059 0.262 0.428, 1.01 0.92
C3H/HeJ m 0.761 0.191   10 0.0603 0.251 0.511, 1.12 1.12
C57BL/10J f 0.312 0.101   10 0.0319 0.324 0.188, 0.488 -1.25
C57BL/10J m 0.392 0.0906   10 0.0287 0.231 0.247, 0.527 -1.04
C57BL/6J f 0.494 0.167   11 0.0505 0.339 0.308, 0.741 -0.27
C57BL/6J m 0.54 0.237   10 0.0751 0.44 0.186, 0.928 -0.17
C57BLKS/J f 0.258 0.0666   10 0.0211 0.258 0.194, 0.404 -1.54
C57BLKS/J m 0.462 0.152   10 0.048 0.328 0.234, 0.755 -0.63
C57BR/cdJ f 0.683 0.236   10 0.0746 0.345 0.307, 1.01 0.76
C57BR/cdJ m 0.866 0.328   10 0.104 0.379 0.501, 1.56 1.73
C57L/J f 0.893 0.241   10 0.0762 0.27 0.558, 1.32 1.89
C57L/J m 1.0 0.312   10 0.0988 0.311 0.55, 1.57 2.52
C58/J f 0.357 0.164   10 0.052 0.46 0.167, 0.629 -1.01
C58/J m 0.375 0.182   10 0.0576 0.486 0.153, 0.715 -1.14
CAST/EiJ f 0.603 0.157   10 0.0498 0.261 0.343, 0.793 0.32
CAST/EiJ m 0.648 0.18   10 0.057 0.278 0.276, 0.889 0.46
CBA/J f 0.4 0.129   9 0.0432 0.323 0.275, 0.613 -0.77
CBA/J m 0.476 0.202   10 0.064 0.425 0.242, 0.783 -0.55
CE/J f 0.303 0.0991   10 0.0314 0.328 0.153, 0.515 -1.3
CE/J m 0.327 0.0482   10 0.0152 0.147 0.239, 0.406 -1.42
CZECHII/EiJ f 0.554 0.194   9 0.0647 0.35 0.316, 0.968 0.06
CZECHII/EiJ m 0.566 0.185   11 0.0557 0.327 0.317, 0.975 -0.02
DBA/2J f 0.765 0.224   10 0.0708 0.293 0.418, 1.15 1.2
DBA/2J m 0.687 0.306   10 0.0968 0.445 0.327, 1.27 0.69
FVB/NJ f 0.403 0.095   10 0.03 0.236 0.224, 0.584 -0.76
FVB/NJ m 0.386 0.193   10 0.061 0.5 0.167, 0.855 -1.07
I/LnJ f 0.657 0.233   10 0.0737 0.355 0.37, 1.11 0.62
I/LnJ m 0.682 0.22   10 0.0695 0.323 0.412, 1.05 0.66
JF1/MsJ f 0.932 0.584   10 0.185 0.626 0.314, 2.26 2.1
JF1/MsJ m 0.791 0.455   10 0.144 0.576 0.227, 1.42 1.3
KK/HlJ f 0.342 0.19   10 0.0602 0.556 0.17, 0.806 -1.09
KK/HlJ m 0.454 0.154   10 0.0488 0.339 0.283, 0.674 -0.67
LP/J f 0.366 0.227   10 0.0719 0.621 0.203, 0.97 -0.96
LP/J m 0.461 0.17   10 0.0539 0.37 0.15, 0.664 -0.63
MA/MyJ f 0.487 0.299   10 0.0946 0.614 0.168, 1.19 -0.3
MA/MyJ m 0.445 0.128   10 0.0405 0.287 0.291, 0.68 -0.73
MOLF/EiJ f 0.809 0.121   10 0.0383 0.15 0.659, 0.995 1.44
MOLF/EiJ m 0.873 0.153   10 0.0483 0.175 0.583, 1.08 1.77
MSM/MsJ f 0.763 0.228   10 0.072 0.299 0.401, 1.07 1.19
MSM/MsJ m 0.726 0.272   10 0.0859 0.374 0.405, 1.22 0.92
NOD/ShiLtJ f 0.825 0.206   10 0.0653 0.25 0.485, 1.26 1.52
NOD/ShiLtJ m 0.73 0.333   10 0.105 0.456 0.215, 1.25 0.94
NON/ShiLtJ f 0.732 0.166   11 0.0502 0.228 0.327, 0.924 1.02
NON/ShiLtJ m 0.706 0.184   9 0.0615 0.261 0.366, 0.952 0.8
NZB/BlNJ f 0.556 0.169   10 0.0535 0.304 0.359, 0.85 0.07
NZB/BlNJ m 0.641 0.273   10 0.0863 0.426 0.309, 1.25 0.42
NZW/LacJ f 0.325 0.0814   10 0.0258 0.251 0.195, 0.428 -1.18
NZW/LacJ m 0.423 0.198   10 0.0626 0.468 0.195, 0.892 -0.86
PERA/EiJ f 0.727 0.119   10 0.0378 0.164 0.469, 0.843 0.99
PERA/EiJ m 0.676 0.145   10 0.0459 0.215 0.453, 0.944 0.62
PL/J f 0.392 0.18   10 0.0568 0.459 0.147, 0.712 -0.82
PL/J m 0.407 0.128   10 0.0405 0.315 0.289, 0.707 -0.95
PWK/PhJ f 0.656 0.209   8 0.0738 0.318 0.363, 1.04 0.61
PWK/PhJ m 0.605 0.118   10 0.0373 0.195 0.347, 0.757 0.21
RIIIS/J f 0.378 0.277   10 0.0875 0.733 0.098, 0.953 -0.89
RIIIS/J m 0.393 0.197   10 0.0624 0.502 0.205, 0.779 -1.03
SEA/GnJ f 0.565 0.179   14 0.0478 0.317 0.325, 0.855 0.12
SEA/GnJ m 0.588 0.252   10 0.0797 0.428 0.342, 1.22 0.11
SJL/J f 0.784 0.167   10 0.0527 0.213 0.526, 1.02 1.3
SJL/J m 0.826 0.174   10 0.055 0.21 0.616, 1.09 1.5
SM/J f 0.291 0.07   10 0.0221 0.241 0.18, 0.438 -1.36
SM/J m 0.314 0.103   10 0.0326 0.328 0.161, 0.513 -1.49
SPRET/EiJ f 0.413 0.187   10 0.0593 0.454 0.162, 0.722 -0.7
SPRET/EiJ m 0.602 0.27   10 0.0853 0.448 0.253, 1.09 0.19
SWR/J f 0.451 0.159   10 0.0501 0.352 0.23, 0.708 -0.5
SWR/J m 0.509 0.102   10 0.0322 0.2 0.361, 0.736 -0.35
WSB/EiJ f 0.646 0.248   7 0.0939 0.385 0.354, 1.05 0.56
WSB/EiJ m 0.482 0.152   8 0.0539 0.317 0.259, 0.754 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3993 0.0667 0.5304 0.2683
129S1/SvImJ m 0.4089 0.0667 0.5399 0.2779
A/J f 0.6051 0.0667 0.7361 0.474
A/J m 0.7022 0.0667 0.8333 0.5712
AKR/J f 0.3653 0.0667 0.4964 0.2343
AKR/J m 0.3034 0.0667 0.4344 0.1724
BALB/cJ f 0.5473 0.0497 0.645 0.4496
BALB/cJ m 0.5201 0.0667 0.6511 0.3891
BTBR T+ Itpr3tf/J f 0.5212 0.0667 0.6522 0.3902
BTBR T+ Itpr3tf/J m 0.5354 0.0667 0.6664 0.4043
BUB/BnJ f 0.4513 0.0667 0.5823 0.3203
BUB/BnJ m 0.486 0.0667 0.6171 0.355
C3H/HeJ f 0.7127 0.0667 0.8437 0.5817
C3H/HeJ m 0.7606 0.0667 0.8916 0.6296
C57BL/10J f 0.3122 0.0667 0.4432 0.1811
C57BL/10J m 0.3924 0.0667 0.5234 0.2614
C57BL/6J f 0.4939 0.0636 0.6188 0.369
C57BL/6J m 0.5403 0.0667 0.6713 0.4093
C57BLKS/J f 0.2585 0.0667 0.3895 0.1274
C57BLKS/J m 0.4623 0.0667 0.5933 0.3313
C57BR/cdJ f 0.6831 0.0667 0.8141 0.552
C57BR/cdJ m 0.8662 0.0667 0.9972 0.7351
C57L/J f 0.8934 0.0667 1.0244 0.7624
C57L/J m 1.0037 0.0667 1.1347 0.8727
C58/J f 0.3572 0.0667 0.4882 0.2262
C58/J m 0.375 0.0667 0.506 0.244
CAST/EiJ f 0.6032 0.0667 0.7342 0.4721
CAST/EiJ m 0.6484 0.0667 0.7794 0.5174
CBA/J f 0.4004 0.0704 0.5385 0.2623
CBA/J m 0.476 0.0667 0.607 0.345
CE/J f 0.3027 0.0667 0.4337 0.1717
CE/J m 0.3272 0.0667 0.4583 0.1962
CZECHII/EiJ f 0.5538 0.0704 0.6919 0.4157
CZECHII/EiJ m 0.5659 0.0636 0.6908 0.441
DBA/2J f 0.7651 0.0667 0.8961 0.634
DBA/2J m 0.6874 0.0667 0.8184 0.5564
FVB/NJ f 0.4025 0.0667 0.5335 0.2715
FVB/NJ m 0.3857 0.0667 0.5167 0.2547
I/LnJ f 0.657 0.0667 0.788 0.526
I/LnJ m 0.6817 0.0667 0.8128 0.5507
JF1/MsJ f 0.9323 0.0667 1.0633 0.8012
JF1/MsJ m 0.7913 0.0667 0.9223 0.6602
KK/HlJ f 0.3421 0.0667 0.4732 0.2111
KK/HlJ m 0.4544 0.0667 0.5854 0.3234
LP/J f 0.3661 0.0667 0.4971 0.2351
LP/J m 0.4605 0.0667 0.5916 0.3295
MA/MyJ f 0.4874 0.0667 0.6184 0.3563
MA/MyJ m 0.4454 0.0667 0.5764 0.3144
MOLF/EiJ f 0.8089 0.0667 0.9399 0.6778
MOLF/EiJ m 0.8729 0.0667 1.0039 0.7418
MSM/MsJ f 0.7625 0.0667 0.8935 0.6315
MSM/MsJ m 0.7258 0.0667 0.8568 0.5948
NOD/ShiLtJ f 0.8253 0.0667 0.9563 0.6943
NOD/ShiLtJ m 0.7305 0.0667 0.8615 0.5995
NON/ShiLtJ f 0.7315 0.0636 0.8565 0.6066
NON/ShiLtJ m 0.7056 0.0704 0.8437 0.5675
NZB/BlNJ f 0.5558 0.0667 0.6868 0.4248
NZB/BlNJ m 0.6409 0.0667 0.772 0.5099
NZW/LacJ f 0.3251 0.0667 0.4561 0.1941
NZW/LacJ m 0.4232 0.0667 0.5543 0.2922
PERA/EiJ f 0.7266 0.0667 0.8576 0.5956
PERA/EiJ m 0.6761 0.0667 0.8071 0.5451
PL/J f 0.3916 0.0667 0.5226 0.2605
PL/J m 0.4071 0.0667 0.5381 0.2761
PWK/PhJ f 0.6562 0.0746 0.8027 0.5097
PWK/PhJ m 0.6048 0.0667 0.7358 0.4738
RIIIS/J f 0.3776 0.0667 0.5086 0.2466
RIIIS/J m 0.3931 0.0667 0.5241 0.2621
SEA/GnJ f 0.5647 0.0564 0.6755 0.454
SEA/GnJ m 0.5881 0.0667 0.7191 0.4571
SJL/J f 0.7835 0.0667 0.9146 0.6525
SJL/J m 0.826 0.0667 0.9571 0.695
SM/J f 0.2909 0.0667 0.4219 0.1599
SM/J m 0.3136 0.0667 0.4446 0.1826
SPRET/EiJ f 0.4127 0.0667 0.5437 0.2817
SPRET/EiJ m 0.6024 0.0667 0.7334 0.4714
SWR/J f 0.4506 0.0667 0.5816 0.3196
SWR/J m 0.5092 0.0667 0.6402 0.3782
WSB/EiJ f 0.6457 0.0798 0.8023 0.4891
WSB/EiJ m 0.4817 0.0746 0.6283 0.3352


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4041 0.0472 0.4968 0.3115
A/J both 0.6537 0.0472 0.7463 0.561
AKR/J both 0.3344 0.0472 0.427 0.2417
BALB/cJ both 0.5337 0.0416 0.6154 0.452
BTBR T+ Itpr3tf/J both 0.5283 0.0472 0.6209 0.4356
BUB/BnJ both 0.4687 0.0472 0.5613 0.376
C3H/HeJ both 0.7366 0.0472 0.8293 0.644
C57BL/10J both 0.3523 0.0472 0.4449 0.2596
C57BL/6J both 0.5171 0.0461 0.6076 0.4266
C57BLKS/J both 0.3604 0.0472 0.453 0.2677
C57BR/cdJ both 0.7746 0.0472 0.8673 0.6819
C57L/J both 0.9485 0.0472 1.0412 0.8559
C58/J both 0.3661 0.0472 0.4588 0.2734
CAST/EiJ both 0.6258 0.0472 0.7184 0.5331
CBA/J both 0.4382 0.0485 0.5334 0.343
CE/J both 0.315 0.0472 0.4076 0.2223
CZECHII/EiJ both 0.5598 0.0474 0.653 0.4667
DBA/2J both 0.7262 0.0472 0.8189 0.6336
FVB/NJ both 0.3941 0.0472 0.4868 0.3014
I/LnJ both 0.6694 0.0472 0.762 0.5767
JF1/MsJ both 0.8618 0.0472 0.9544 0.7691
KK/HlJ both 0.3983 0.0472 0.4909 0.3056
LP/J both 0.4133 0.0472 0.506 0.3207
MA/MyJ both 0.4664 0.0472 0.559 0.3737
MOLF/EiJ both 0.8409 0.0472 0.9335 0.7482
MSM/MsJ both 0.7441 0.0472 0.8368 0.6515
NOD/ShiLtJ both 0.7779 0.0472 0.8706 0.6852
NON/ShiLtJ both 0.7186 0.0474 0.8117 0.6255
NZB/BlNJ both 0.5984 0.0472 0.691 0.5057
NZW/LacJ both 0.3742 0.0472 0.4668 0.2815
PERA/EiJ both 0.7014 0.0472 0.794 0.6087
PL/J both 0.3993 0.0472 0.492 0.3067
PWK/PhJ both 0.6305 0.0501 0.7288 0.5322
RIIIS/J both 0.3854 0.0472 0.478 0.2927
SEA/GnJ both 0.5764 0.0437 0.6622 0.4906
SJL/J both 0.8048 0.0472 0.8975 0.7121
SM/J both 0.3022 0.0472 0.3949 0.2096
SPRET/EiJ both 0.5076 0.0472 0.6002 0.4149
SWR/J both 0.4799 0.0472 0.5726 0.3872
WSB/EiJ both 0.5637 0.0546 0.671 0.4565




  GWAS USING LINEAR MIXED MODELS