Project measure / variable:   Willott1   PPI_12

ID, description, units MPD:9109   PPI_12   mean prepulse inhibition (PPI), 70dB   [ratio]  12 kHz  
Data set, strains Willott1   inbred w/CC7   40 strains     sex: both     age: 5-6wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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Willott1 - mean prepulse inhibition (PPI), 70dB 12 kHz



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains40 strains
Mean of the strain means0.566   ratio 0.555   ratio
Median of the strain means0.544   ratio 0.492   ratio
SD of the strain means± 0.192 ± 0.192
Coefficient of variation (CV)0.340 0.345
Min–max range of strain means0.264   –   0.996   ratio 0.299   –   1.16   ratio
Mean sample size per strain10.1   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0231 0.0231 0.4987 0.4803
strain 39 27.3957 0.7025 15.1629 < 0.0001
sex:strain 39 1.247 0.032 0.6902 0.9248
Residuals 725 33.5872 0.0463


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.479 0.322   10 0.102 0.671 0.14, 1.01 -0.45
129S1/SvImJ m 0.452 0.241   10 0.0763 0.533 0.207, 1.0 -0.54
A/J f 0.555 0.243   10 0.0768 0.438 0.326, 1.17 -0.06
A/J m 0.484 0.199   10 0.063 0.412 0.2, 0.785 -0.37
AKR/J f 0.413 0.2   10 0.0631 0.484 0.197, 0.903 -0.79
AKR/J m 0.322 0.0865   10 0.0273 0.268 0.167, 0.464 -1.22
BALB/cJ f 0.56 0.186   18 0.0438 0.332 0.244, 0.947 -0.03
BALB/cJ m 0.564 0.189   10 0.0599 0.336 0.271, 0.985 0.05
BTBR T+ Itpr3tf/J f 0.617 0.242   10 0.0764 0.392 0.279, 0.986 0.27
BTBR T+ Itpr3tf/J m 0.517 0.2   10 0.0633 0.388 0.192, 0.851 -0.2
BUB/BnJ f 0.396 0.114   10 0.036 0.288 0.263, 0.563 -0.88
BUB/BnJ m 0.462 0.296   10 0.0936 0.641 0.265, 1.28 -0.49
C3H/HeJ f 0.839 0.238   10 0.0753 0.284 0.551, 1.38 1.42
C3H/HeJ m 0.714 0.204   10 0.0644 0.285 0.454, 1.06 0.83
C57BL/10J f 0.328 0.122   10 0.0385 0.371 0.226, 0.59 -1.24
C57BL/10J m 0.404 0.106   10 0.0335 0.262 0.267, 0.641 -0.79
C57BL/6J f 0.534 0.124   11 0.0374 0.232 0.325, 0.686 -0.16
C57BL/6J m 0.469 0.183   10 0.0577 0.39 0.152, 0.751 -0.45
C57BLKS/J f 0.304 0.0983   10 0.0311 0.323 0.138, 0.452 -1.36
C57BLKS/J m 0.408 0.283   10 0.0894 0.692 0.145, 0.966 -0.77
C57BR/cdJ f 0.758 0.241   10 0.0763 0.319 0.281, 1.18 1.0
C57BR/cdJ m 0.848 0.223   10 0.0707 0.264 0.377, 1.17 1.53
C57L/J f 0.996 0.24   10 0.0759 0.241 0.73, 1.48 2.24
C57L/J m 1.16 0.43   10 0.136 0.371 0.682, 2.23 3.16
C58/J f 0.437 0.172   10 0.0544 0.393 0.196, 0.777 -0.67
C58/J m 0.404 0.145   10 0.0459 0.359 0.17, 0.556 -0.79
CAST/EiJ f 0.755 0.312   10 0.0987 0.413 0.396, 1.45 0.99
CAST/EiJ m 0.705 0.258   10 0.0816 0.366 0.263, 1.04 0.78
CBA/J f 0.465 0.127   9 0.0423 0.273 0.283, 0.649 -0.52
CBA/J m 0.494 0.41   10 0.13 0.83 0.234, 1.63 -0.32
CE/J f 0.333 0.122   10 0.0386 0.367 0.228, 0.657 -1.21
CE/J m 0.299 0.0732   10 0.0231 0.244 0.189, 0.429 -1.34
CZECHII/EiJ f 0.554 0.218   9 0.0727 0.394 0.256, 0.933 -0.06
CZECHII/EiJ m 0.49 0.207   11 0.0624 0.422 0.243, 0.999 -0.34
DBA/2J f 0.85 0.208   10 0.0659 0.245 0.546, 1.21 1.48
DBA/2J m 0.677 0.173   10 0.0548 0.256 0.476, 1.0 0.64
FVB/NJ f 0.478 0.15   10 0.0474 0.314 0.301, 0.838 -0.46
FVB/NJ m 0.467 0.137   10 0.0434 0.294 0.302, 0.686 -0.46
I/LnJ f 0.592 0.224   10 0.0707 0.378 0.371, 1.05 0.14
I/LnJ m 0.705 0.268   10 0.0846 0.38 0.318, 1.17 0.78
JF1/MsJ f 0.74 0.41   10 0.13 0.555 0.237, 1.42 0.91
JF1/MsJ m 0.737 0.489   10 0.155 0.663 0.158, 1.31 0.95
KK/HlJ f 0.368 0.105   10 0.0332 0.286 0.268, 0.596 -1.03
KK/HlJ m 0.402 0.123   10 0.0389 0.306 0.211, 0.576 -0.8
LP/J f 0.409 0.206   10 0.065 0.503 0.255, 0.917 -0.81
LP/J m 0.449 0.194   10 0.0614 0.432 0.151, 0.797 -0.55
MA/MyJ f 0.457 0.236   10 0.0745 0.515 0.198, 0.961 -0.56
MA/MyJ m 0.388 0.143   10 0.0453 0.37 0.212, 0.718 -0.87
MOLF/EiJ f 0.861 0.154   10 0.0488 0.179 0.699, 1.11 1.54
MOLF/EiJ m 0.815 0.0944   10 0.0299 0.116 0.656, 0.943 1.36
MSM/MsJ f 0.804 0.234   10 0.0739 0.291 0.47, 1.1 1.24
MSM/MsJ m 0.756 0.309   10 0.0976 0.408 0.446, 1.48 1.05
NOD/ShiLtJ f 0.859 0.235   10 0.0742 0.273 0.531, 1.2 1.53
NOD/ShiLtJ m 0.754 0.371   10 0.117 0.492 0.261, 1.41 1.04
NON/ShiLtJ f 0.745 0.146   11 0.0439 0.195 0.427, 0.911 0.93
NON/ShiLtJ m 0.905 0.411   9 0.137 0.454 0.376, 1.62 1.83
NZB/BlNJ f 0.763 0.242   10 0.0765 0.317 0.365, 1.07 1.03
NZB/BlNJ m 0.688 0.252   10 0.0797 0.367 0.38, 1.26 0.69
NZW/LacJ f 0.399 0.141   10 0.0447 0.354 0.152, 0.634 -0.87
NZW/LacJ m 0.355 0.134   10 0.0423 0.377 0.228, 0.595 -1.04
PERA/EiJ f 0.647 0.0992   10 0.0314 0.153 0.543, 0.818 0.42
PERA/EiJ m 0.624 0.18   10 0.0569 0.288 0.445, 1.02 0.36
PL/J f 0.379 0.133   10 0.0421 0.352 0.243, 0.641 -0.97
PL/J m 0.35 0.0737   10 0.0233 0.211 0.234, 0.455 -1.07
PWK/PhJ f 0.585 0.156   8 0.0551 0.266 0.322, 0.812 0.1
PWK/PhJ m 0.519 0.12   10 0.0378 0.231 0.363, 0.759 -0.19
RIIIS/J f 0.429 0.274   10 0.0865 0.637 0.172, 1.06 -0.71
RIIIS/J m 0.363 0.182   10 0.0575 0.501 0.164, 0.755 -1.0
SEA/GnJ f 0.468 0.156   14 0.0417 0.334 0.203, 0.723 -0.51
SEA/GnJ m 0.451 0.174   10 0.055 0.385 0.189, 0.713 -0.54
SJL/J f 0.853 0.232   10 0.0734 0.272 0.593, 1.3 1.5
SJL/J m 0.81 0.177   10 0.0559 0.218 0.67, 1.23 1.33
SM/J f 0.264 0.043   10 0.0136 0.163 0.187, 0.309 -1.57
SM/J m 0.299 0.105   10 0.0332 0.351 0.183, 0.536 -1.34
SPRET/EiJ f 0.327 0.0934   10 0.0295 0.286 0.198, 0.459 -1.24
SPRET/EiJ m 0.497 0.205   10 0.0648 0.412 0.201, 0.921 -0.3
SWR/J f 0.447 0.0973   10 0.0308 0.217 0.295, 0.595 -0.62
SWR/J m 0.482 0.115   10 0.0364 0.239 0.313, 0.745 -0.38
WSB/EiJ f 0.576 0.13   7 0.049 0.225 0.415, 0.752 0.05
WSB/EiJ m 0.516 0.128   8 0.0451 0.248 0.401, 0.769 -0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.4794 0.0681 0.6131 0.3458
129S1/SvImJ m 0.4523 0.0681 0.5859 0.3187
A/J f 0.5547 0.0681 0.6883 0.4211
A/J m 0.4839 0.0681 0.6175 0.3503
AKR/J f 0.4125 0.0681 0.5462 0.2789
AKR/J m 0.3222 0.0681 0.4558 0.1886
BALB/cJ f 0.5597 0.0507 0.6593 0.4601
BALB/cJ m 0.5636 0.0681 0.6972 0.43
BTBR T+ Itpr3tf/J f 0.6167 0.0681 0.7503 0.4831
BTBR T+ Itpr3tf/J m 0.5166 0.0681 0.6502 0.383
BUB/BnJ f 0.3955 0.0681 0.5292 0.2619
BUB/BnJ m 0.462 0.0681 0.5956 0.3284
C3H/HeJ f 0.8392 0.0681 0.9728 0.7056
C3H/HeJ m 0.7142 0.0681 0.8478 0.5806
C57BL/10J f 0.3279 0.0681 0.4615 0.1942
C57BL/10J m 0.4043 0.0681 0.5379 0.2707
C57BL/6J f 0.5344 0.0649 0.6618 0.407
C57BL/6J m 0.4686 0.0681 0.6022 0.3349
C57BLKS/J f 0.3041 0.0681 0.4377 0.1704
C57BLKS/J m 0.4081 0.0681 0.5418 0.2745
C57BR/cdJ f 0.7576 0.0681 0.8912 0.624
C57BR/cdJ m 0.8477 0.0681 0.9813 0.714
C57L/J f 0.9961 0.0681 1.1297 0.8625
C57L/J m 1.1576 0.0681 1.2912 1.0239
C58/J f 0.4372 0.0681 0.5708 0.3036
C58/J m 0.4041 0.0681 0.5377 0.2704
CAST/EiJ f 0.7552 0.0681 0.8888 0.6215
CAST/EiJ m 0.7052 0.0681 0.8388 0.5716
CBA/J f 0.4646 0.0717 0.6054 0.3237
CBA/J m 0.494 0.0681 0.6277 0.3604
CE/J f 0.3327 0.0681 0.4663 0.199
CE/J m 0.2993 0.0681 0.433 0.1657
CZECHII/EiJ f 0.5539 0.0717 0.6948 0.4131
CZECHII/EiJ m 0.4901 0.0649 0.6175 0.3627
DBA/2J f 0.8497 0.0681 0.9833 0.7161
DBA/2J m 0.6772 0.0681 0.8108 0.5436
FVB/NJ f 0.4783 0.0681 0.6119 0.3446
FVB/NJ m 0.4671 0.0681 0.6007 0.3335
I/LnJ f 0.5919 0.0681 0.7255 0.4582
I/LnJ m 0.7047 0.0681 0.8383 0.5711
JF1/MsJ f 0.7396 0.0681 0.8732 0.6059
JF1/MsJ m 0.7371 0.0681 0.8707 0.6034
KK/HlJ f 0.3677 0.0681 0.5013 0.2341
KK/HlJ m 0.4016 0.0681 0.5353 0.268
LP/J f 0.4086 0.0681 0.5422 0.275
LP/J m 0.4492 0.0681 0.5828 0.3155
MA/MyJ f 0.4573 0.0681 0.5909 0.3236
MA/MyJ m 0.3875 0.0681 0.5212 0.2539
MOLF/EiJ f 0.8608 0.0681 0.9944 0.7272
MOLF/EiJ m 0.8154 0.0681 0.949 0.6817
MSM/MsJ f 0.8037 0.0681 0.9373 0.67
MSM/MsJ m 0.7562 0.0681 0.8899 0.6226
NOD/ShiLtJ f 0.8588 0.0681 0.9924 0.7251
NOD/ShiLtJ m 0.7536 0.0681 0.8873 0.62
NON/ShiLtJ f 0.7454 0.0649 0.8728 0.618
NON/ShiLtJ m 0.9049 0.0717 1.0457 0.764
NZB/BlNJ f 0.763 0.0681 0.8966 0.6294
NZB/BlNJ m 0.6876 0.0681 0.8212 0.5539
NZW/LacJ f 0.3993 0.0681 0.533 0.2657
NZW/LacJ m 0.3548 0.0681 0.4884 0.2212
PERA/EiJ f 0.6473 0.0681 0.7809 0.5137
PERA/EiJ m 0.6239 0.0681 0.7576 0.4903
PL/J f 0.3786 0.0681 0.5122 0.2449
PL/J m 0.3498 0.0681 0.4834 0.2162
PWK/PhJ f 0.5853 0.0761 0.7346 0.4359
PWK/PhJ m 0.5185 0.0681 0.6522 0.3849
RIIIS/J f 0.4293 0.0681 0.5629 0.2956
RIIIS/J m 0.3632 0.0681 0.4968 0.2296
SEA/GnJ f 0.4681 0.0575 0.581 0.3551
SEA/GnJ m 0.4513 0.0681 0.585 0.3177
SJL/J f 0.8534 0.0681 0.987 0.7197
SJL/J m 0.8102 0.0681 0.9438 0.6766
SM/J f 0.2643 0.0681 0.3979 0.1306
SM/J m 0.2995 0.0681 0.4331 0.1659
SPRET/EiJ f 0.3268 0.0681 0.4604 0.1931
SPRET/EiJ m 0.4971 0.0681 0.6307 0.3634
SWR/J f 0.4475 0.0681 0.5811 0.3139
SWR/J m 0.4822 0.0681 0.6159 0.3486
WSB/EiJ f 0.5758 0.0814 0.7355 0.4161
WSB/EiJ m 0.5158 0.0761 0.6652 0.3664


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4659 0.0481 0.5603 0.3714
A/J both 0.5193 0.0481 0.6138 0.4248
AKR/J both 0.3674 0.0481 0.4619 0.2729
BALB/cJ both 0.5616 0.0424 0.645 0.4783
BTBR T+ Itpr3tf/J both 0.5666 0.0481 0.6611 0.4722
BUB/BnJ both 0.4288 0.0481 0.5233 0.3343
C3H/HeJ both 0.7767 0.0481 0.8712 0.6822
C57BL/10J both 0.3661 0.0481 0.4606 0.2716
C57BL/6J both 0.5015 0.047 0.5938 0.4092
C57BLKS/J both 0.3561 0.0481 0.4506 0.2616
C57BR/cdJ both 0.8026 0.0481 0.8971 0.7081
C57L/J both 1.0768 0.0481 1.1713 0.9823
C58/J both 0.4206 0.0481 0.5151 0.3261
CAST/EiJ both 0.7302 0.0481 0.8247 0.6357
CBA/J both 0.4793 0.0494 0.5764 0.3822
CE/J both 0.316 0.0481 0.4105 0.2215
CZECHII/EiJ both 0.522 0.0484 0.617 0.4271
DBA/2J both 0.7635 0.0481 0.8579 0.669
FVB/NJ both 0.4727 0.0481 0.5672 0.3782
I/LnJ both 0.6483 0.0481 0.7428 0.5538
JF1/MsJ both 0.7383 0.0481 0.8328 0.6438
KK/HlJ both 0.3847 0.0481 0.4792 0.2902
LP/J both 0.4289 0.0481 0.5234 0.3344
MA/MyJ both 0.4224 0.0481 0.5169 0.3279
MOLF/EiJ both 0.8381 0.0481 0.9326 0.7436
MSM/MsJ both 0.7799 0.0481 0.8744 0.6855
NOD/ShiLtJ both 0.8062 0.0481 0.9007 0.7117
NON/ShiLtJ both 0.8251 0.0484 0.9201 0.7302
NZB/BlNJ both 0.7253 0.0481 0.8198 0.6308
NZW/LacJ both 0.3771 0.0481 0.4716 0.2826
PERA/EiJ both 0.6356 0.0481 0.7301 0.5411
PL/J both 0.3642 0.0481 0.4587 0.2697
PWK/PhJ both 0.5519 0.051 0.6521 0.4517
RIIIS/J both 0.3962 0.0481 0.4907 0.3017
SEA/GnJ both 0.4597 0.0446 0.5472 0.3722
SJL/J both 0.8318 0.0481 0.9263 0.7373
SM/J both 0.2819 0.0481 0.3764 0.1874
SPRET/EiJ both 0.4119 0.0481 0.5064 0.3174
SWR/J both 0.4649 0.0481 0.5594 0.3704
WSB/EiJ both 0.5458 0.0557 0.6551 0.4365




  GWAS USING LINEAR MIXED MODELS