Phenotype measure:   Willott1   ASR_habituation

ID, description, units MPD:9107   ASR_habituation   habituation: ratio of final 4 trials to initial 4 trials (<1.0=diminished ASR)   [ratio]
Data set, strains Willott1   inbred w/CC7   40 strains     sex: both     age: 5-6wks
Procedure acoustic startle test
Ontology mappings

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Willott1 - habituation: ratio of final 4 trials to initial 4 trials (<1.0=diminished ASR)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains40 strains
Mean of the strain means0.994   ratio 1.000   ratio
Median of the strain means0.952   ratio 0.978   ratio
SD of the strain means± 0.259 ± 0.221
Coefficient of variation (CV)0.261 0.221
Min–max range of strain means0.611   –   1.68   ratio 0.660   –   1.74   ratio
Mean sample size per strain10.1   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0113 0.0113 0.0332 0.8556
strain 39 31.0144 0.7952 2.3318 < 0.0001
sex:strain 39 14.4579 0.3707 1.087 0.3327
Residuals 725 247.2537 0.341


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.611 0.221   10 0.0698 0.361 0.247, 1.1 -1.48
129S1/SvImJ m 1.22 0.981   10 0.31 0.804 0.224, 3.6 0.99
A/J f 0.908 0.281   10 0.0888 0.309 0.613, 1.35 -0.33
A/J m 1.02 0.462   10 0.146 0.452 0.433, 2.01 0.09
AKR/J f 1.43 0.755   10 0.239 0.528 0.383, 2.67 1.68
AKR/J m 1.13 0.649   10 0.205 0.576 0.241, 2.1 0.59
BALB/cJ f 0.894 0.479   18 0.113 0.536 0.235, 1.98 -0.39
BALB/cJ m 0.943 0.401   10 0.127 0.425 0.402, 1.57 -0.26
BTBR T+ Itpr3tf/J f 0.979 0.477   10 0.151 0.487 0.324, 1.71 -0.06
BTBR T+ Itpr3tf/J m 0.858 0.317   10 0.1 0.37 0.427, 1.51 -0.64
BUB/BnJ f 0.89 0.332   10 0.105 0.373 0.49, 1.45 -0.4
BUB/BnJ m 1.05 0.324   10 0.102 0.307 0.617, 1.56 0.23
C3H/HeJ f 0.897 0.628   10 0.199 0.701 0.14, 2.21 -0.37
C3H/HeJ m 0.791 0.733   10 0.232 0.927 0.228, 2.73 -0.94
C57BL/10J f 0.711 0.254   10 0.0802 0.357 0.336, 1.03 -1.09
C57BL/10J m 0.706 0.344   10 0.109 0.487 0.249, 1.4 -1.33
C57BL/6J f 0.772 0.319   11 0.0961 0.413 0.383, 1.2 -0.86
C57BL/6J m 0.961 0.473   10 0.15 0.493 0.317, 1.57 -0.18
C57BLKS/J f 0.802 0.429   10 0.136 0.534 0.318, 1.88 -0.74
C57BLKS/J m 1.13 1.02   10 0.322 0.901 0.356, 3.95 0.59
C57BR/cdJ f 0.985 0.612   10 0.194 0.622 0.42, 2.39 -0.04
C57BR/cdJ m 1.0 0.408   10 0.129 0.407 0.261, 1.66 0.0
C57L/J f 1.57 1.44   10 0.456 0.915 0.313, 4.74 2.22
C57L/J m 1.09 0.838   10 0.265 0.77 0.253, 2.5 0.41
C58/J f 0.869 0.495   10 0.156 0.569 0.273, 1.76 -0.48
C58/J m 0.868 0.366   10 0.116 0.421 0.293, 1.45 -0.6
CAST/EiJ f 1.63 1.38   10 0.438 0.851 0.613, 4.85 2.45
CAST/EiJ m 1.02 0.203   10 0.0641 0.198 0.613, 1.28 0.09
CBA/J f 1.07 0.562   9 0.187 0.527 0.538, 1.79 0.29
CBA/J m 1.13 0.782   10 0.247 0.69 0.474, 3.06 0.59
CE/J f 0.991 0.588   10 0.186 0.593 0.303, 2.38 -0.01
CE/J m 1.0 0.323   10 0.102 0.322 0.448, 1.43 0.0
CZECHII/EiJ f 1.32 0.407   9 0.136 0.309 0.741, 2.01 1.26
CZECHII/EiJ m 1.49 0.747   11 0.225 0.502 0.407, 2.76 2.21
DBA/2J f 0.793 0.501   10 0.158 0.631 0.182, 1.81 -0.78
DBA/2J m 0.675 0.349   10 0.11 0.517 0.268, 1.37 -1.47
FVB/NJ f 0.944 0.338   10 0.107 0.358 0.476, 1.56 -0.19
FVB/NJ m 0.995 0.527   10 0.166 0.529 0.323, 1.93 -0.02
I/LnJ f 1.12 0.592   10 0.187 0.527 0.226, 2.05 0.49
I/LnJ m 1.74 1.09   10 0.343 0.626 0.441, 3.58 3.34
JF1/MsJ f 0.689 0.282   10 0.0891 0.409 0.197, 1.16 -1.18
JF1/MsJ m 0.837 0.402   10 0.127 0.48 0.182, 1.41 -0.74
KK/HlJ f 0.96 0.533   10 0.169 0.556 0.376, 2.0 -0.13
KK/HlJ m 0.741 0.456   10 0.144 0.615 0.167, 1.7 -1.17
LP/J f 0.86 0.392   10 0.124 0.456 0.405, 1.67 -0.52
LP/J m 0.808 0.402   10 0.127 0.498 0.319, 1.66 -0.87
MA/MyJ f 0.896 0.389   10 0.123 0.434 0.556, 1.7 -0.38
MA/MyJ m 0.748 0.469   10 0.148 0.627 0.361, 2.04 -1.14
MOLF/EiJ f 1.01 0.386   10 0.122 0.381 0.386, 1.82 0.06
MOLF/EiJ m 0.885 0.394   10 0.124 0.445 0.287, 1.5 -0.52
MSM/MsJ f 1.09 0.73   10 0.231 0.67 0.107, 2.74 0.37
MSM/MsJ m 1.07 0.767   10 0.242 0.717 0.337, 2.82 0.32
NOD/ShiLtJ f 1.2 0.507   10 0.16 0.421 0.549, 2.08 0.79
NOD/ShiLtJ m 0.952 0.59   10 0.187 0.619 0.298, 2.25 -0.22
NON/ShiLtJ f 1.68 1.28   11 0.386 0.761 0.602, 3.88 2.64
NON/ShiLtJ m 0.958 0.593   9 0.198 0.619 0.36, 2.24 -0.19
NZB/BlNJ f 0.859 0.273   10 0.0862 0.318 0.417, 1.29 -0.52
NZB/BlNJ m 0.947 0.611   10 0.193 0.645 0.364, 2.22 -0.24
NZW/LacJ f 1.02 0.519   10 0.164 0.508 0.481, 2.1 0.1
NZW/LacJ m 1.39 0.871   10 0.275 0.628 0.12, 2.95 1.76
PERA/EiJ f 0.749 0.488   10 0.154 0.651 0.324, 1.64 -0.95
PERA/EiJ m 0.917 0.375   10 0.119 0.409 0.418, 1.55 -0.37
PL/J f 1.03 0.506   10 0.16 0.492 0.469, 2.1 0.14
PL/J m 1.02 0.311   10 0.0984 0.304 0.699, 1.68 0.09
PWK/PhJ f 0.969 0.367   8 0.13 0.378 0.592, 1.63 -0.1
PWK/PhJ m 1.26 0.8   10 0.253 0.637 0.347, 3.06 1.18
RIIIS/J f 1.45 0.784   10 0.248 0.541 0.714, 3.42 1.76
RIIIS/J m 1.13 0.487   10 0.154 0.43 0.452, 1.87 0.59
SEA/GnJ f 0.939 0.468   14 0.125 0.498 0.273, 2.08 -0.21
SEA/GnJ m 1.17 0.724   10 0.229 0.617 0.437, 2.58 0.77
SJL/J f 0.752 0.216   10 0.0684 0.288 0.532, 1.16 -0.93
SJL/J m 0.804 0.409   10 0.129 0.508 0.297, 1.46 -0.89
SM/J f 1.0 0.245   10 0.0776 0.245 0.599, 1.35 0.02
SM/J m 1.19 0.411   10 0.13 0.346 0.37, 1.7 0.86
SPRET/EiJ f 0.821 0.388   10 0.123 0.473 0.413, 1.65 -0.67
SPRET/EiJ m 0.66 0.397   10 0.126 0.602 0.18, 1.58 -1.54
SWR/J f 0.982 0.207   10 0.0656 0.211 0.714, 1.31 -0.05
SWR/J m 0.894 0.42   10 0.133 0.47 0.336, 1.54 -0.48
WSB/EiJ f 0.625 0.305   7 0.115 0.487 0.397, 1.22 -1.42
WSB/EiJ m 0.8 0.267   8 0.0943 0.333 0.346, 1.19 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6111 0.1847 0.9737 0.2485
129S1/SvImJ m 1.2197 0.1847 1.5823 0.8571
A/J f 0.9081 0.1847 1.2707 0.5455
A/J m 1.0204 0.1847 1.383 0.6578
AKR/J f 1.4293 0.1847 1.7919 1.0667
AKR/J m 1.1272 0.1847 1.4898 0.7646
BALB/cJ f 0.8938 0.1376 1.1641 0.6236
BALB/cJ m 0.9432 0.1847 1.3058 0.5806
BTBR T+ Itpr3tf/J f 0.9787 0.1847 1.3413 0.6161
BTBR T+ Itpr3tf/J m 0.858 0.1847 1.2206 0.4954
BUB/BnJ f 0.8904 0.1847 1.253 0.5278
BUB/BnJ m 1.0547 0.1847 1.4173 0.6921
C3H/HeJ f 0.8966 0.1847 1.2592 0.534
C3H/HeJ m 0.791 0.1847 1.1536 0.4284
C57BL/10J f 0.7109 0.1847 1.0735 0.3483
C57BL/10J m 0.7057 0.1847 1.0683 0.3431
C57BL/6J f 0.7721 0.1761 1.1178 0.4264
C57BL/6J m 0.9609 0.1847 1.3235 0.5983
C57BLKS/J f 0.8024 0.1847 1.165 0.4398
C57BLKS/J m 1.1299 0.1847 1.4925 0.7673
C57BR/cdJ f 0.9852 0.1847 1.3478 0.6226
C57BR/cdJ m 1.0007 0.1847 1.3633 0.6381
C57L/J f 1.5741 0.1847 1.9367 1.2115
C57L/J m 1.0887 0.1847 1.4513 0.7261
C58/J f 0.8689 0.1847 1.2315 0.5063
C58/J m 0.8684 0.1847 1.231 0.5058
CAST/EiJ f 1.6263 0.1847 1.9889 1.2637
CAST/EiJ m 1.0221 0.1847 1.3847 0.6595
CBA/J f 1.0654 0.1947 1.4476 0.6833
CBA/J m 1.1339 0.1847 1.4965 0.7713
CE/J f 0.9906 0.1847 1.3532 0.628
CE/J m 1.0012 0.1847 1.3638 0.6386
CZECHII/EiJ f 1.3194 0.1947 1.7016 0.9373
CZECHII/EiJ m 1.488 0.1761 1.8337 1.1423
DBA/2J f 0.7929 0.1847 1.1555 0.4303
DBA/2J m 0.6754 0.1847 1.038 0.3128
FVB/NJ f 0.9439 0.1847 1.3065 0.5813
FVB/NJ m 0.9946 0.1847 1.3572 0.632
I/LnJ f 1.1223 0.1847 1.4849 0.7597
I/LnJ m 1.735 0.1847 2.0976 1.3724
JF1/MsJ f 0.6894 0.1847 1.052 0.3268
JF1/MsJ m 0.8366 0.1847 1.1992 0.474
KK/HlJ f 0.9602 0.1847 1.3228 0.5976
KK/HlJ m 0.7406 0.1847 1.1032 0.378
LP/J f 0.8604 0.1847 1.223 0.4978
LP/J m 0.808 0.1847 1.1706 0.4454
MA/MyJ f 0.8959 0.1847 1.2585 0.5333
MA/MyJ m 0.7476 0.1847 1.1102 0.385
MOLF/EiJ f 1.0107 0.1847 1.3733 0.6481
MOLF/EiJ m 0.8849 0.1847 1.2475 0.5223
MSM/MsJ f 1.0904 0.1847 1.453 0.7278
MSM/MsJ m 1.0699 0.1847 1.4325 0.7073
NOD/ShiLtJ f 1.2036 0.1847 1.5662 0.841
NOD/ShiLtJ m 0.9525 0.1847 1.3151 0.5899
NON/ShiLtJ f 1.6818 0.1761 2.0275 1.3361
NON/ShiLtJ m 0.9578 0.1947 1.3399 0.5756
NZB/BlNJ f 0.8588 0.1847 1.2214 0.4962
NZB/BlNJ m 0.9474 0.1847 1.31 0.5848
NZW/LacJ f 1.0211 0.1847 1.3837 0.6585
NZW/LacJ m 1.387 0.1847 1.7496 1.0244
PERA/EiJ f 0.7491 0.1847 1.1117 0.3865
PERA/EiJ m 0.9171 0.1847 1.2797 0.5545
PL/J f 1.0276 0.1847 1.3902 0.665
PL/J m 1.024 0.1847 1.3866 0.6614
PWK/PhJ f 0.9691 0.2065 1.3745 0.5638
PWK/PhJ m 1.2564 0.1847 1.619 0.8938
RIIIS/J f 1.4487 0.1847 1.8113 1.0861
RIIIS/J m 1.1322 0.1847 1.4948 0.7696
SEA/GnJ f 0.9393 0.1561 1.2457 0.6329
SEA/GnJ m 1.1719 0.1847 1.5345 0.8093
SJL/J f 0.752 0.1847 1.1146 0.3894
SJL/J m 0.8045 0.1847 1.1671 0.4419
SM/J f 1.0013 0.1847 1.3639 0.6387
SM/J m 1.1856 0.1847 1.5482 0.823
SPRET/EiJ f 0.8208 0.1847 1.1834 0.4582
SPRET/EiJ m 0.6597 0.1847 1.0223 0.2971
SWR/J f 0.9817 0.1847 1.3443 0.6191
SWR/J m 0.894 0.1847 1.2566 0.5314
WSB/EiJ f 0.6253 0.2207 1.0586 0.1919
WSB/EiJ m 0.7996 0.2065 1.205 0.3943


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.9154 0.1306 1.1718 0.659
A/J both 0.9642 0.1306 1.2206 0.7079
AKR/J both 1.2783 0.1306 1.5346 1.0219
BALB/cJ both 0.9185 0.1152 1.1446 0.6924
BTBR T+ Itpr3tf/J both 0.9184 0.1306 1.1747 0.662
BUB/BnJ both 0.9726 0.1306 1.2289 0.7162
C3H/HeJ both 0.8438 0.1306 1.1002 0.5874
C57BL/10J both 0.7083 0.1306 0.9647 0.4519
C57BL/6J both 0.8665 0.1276 1.117 0.616
C57BLKS/J both 0.9661 0.1306 1.2225 0.7098
C57BR/cdJ both 0.993 0.1306 1.2493 0.7366
C57L/J both 1.3314 0.1306 1.5878 1.075
C58/J both 0.8686 0.1306 1.125 0.6123
CAST/EiJ both 1.3242 0.1306 1.5806 1.0678
CBA/J both 1.0997 0.1342 1.3631 0.8363
CE/J both 0.9959 0.1306 1.2523 0.7395
CZECHII/EiJ both 1.4037 0.1312 1.6614 1.1461
DBA/2J both 0.7341 0.1306 0.9905 0.4778
FVB/NJ both 0.9692 0.1306 1.2256 0.7129
I/LnJ both 1.4286 0.1306 1.685 1.1723
JF1/MsJ both 0.763 0.1306 1.0194 0.5066
KK/HlJ both 0.8504 0.1306 1.1068 0.594
LP/J both 0.8342 0.1306 1.0906 0.5778
MA/MyJ both 0.8218 0.1306 1.0781 0.5654
MOLF/EiJ both 0.9478 0.1306 1.2042 0.6914
MSM/MsJ both 1.0801 0.1306 1.3365 0.8238
NOD/ShiLtJ both 1.078 0.1306 1.3344 0.8217
NON/ShiLtJ both 1.3198 0.1312 1.5775 1.0621
NZB/BlNJ both 0.9031 0.1306 1.1595 0.6467
NZW/LacJ both 1.204 0.1306 1.4604 0.9477
PERA/EiJ both 0.8331 0.1306 1.0895 0.5767
PL/J both 1.0258 0.1306 1.2822 0.7694
PWK/PhJ both 1.1128 0.1385 1.3847 0.8408
RIIIS/J both 1.2904 0.1306 1.5468 1.0341
SEA/GnJ both 1.0556 0.1209 1.2929 0.8182
SJL/J both 0.7783 0.1306 1.0346 0.5219
SM/J both 1.0934 0.1306 1.3498 0.8371
SPRET/EiJ both 0.7402 0.1306 0.9966 0.4839
SWR/J both 0.9378 0.1306 1.1942 0.6815
WSB/EiJ both 0.7125 0.1511 1.0091 0.4158




  GWAS USING LINEAR MIXED MODELS