Project measure / variable:   CSNA03   dist_d3_d11_auc_cont_in

ID, description, units MPD:90437   dist_d3_d11_auc_cont_in   distance traveled, last 60 min (post-injection), Day 3 to Day 11 AUC, saline control, founders    
Data set, strains CSNA03   inbred w/CC8   9 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, last 60 min (post-injection), Day 3 to Day 11 AUC, saline control, founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means76232.0   None 55953.0   None
Median of the strain means64703.0   None 47598.0   None
SD of the strain means± 65592.0 ± 44895.0
Coefficient of variation (CV)0.8604 0.8024
Min–max range of strain means3560.0   –   173632.0   None 2501.0   –   117299.0   None
Mean sample size per strain6.4   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17400104401.9595 17400104401.9595 21.5309 < 0.0001
strain 8 347632115717.5724 43454014464.6965 53.77 < 0.0001
sex:strain 8 18949921988.9144 2368740248.6143 2.9311 0.0056
Residuals 98 79198318726.3795 808146109.4529


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3560.0 4180.0   8 1478.0 1.1742 25.889, 10262.0 -1.11
129S1/SvImJ m 2501.0 2718.0   8 961.1 1.0871 -1.19
A/J f 13225.0 7960.0   5 3560.0 0.6019 3301.0, 23135.0 -0.96
A/J m 11253.0 6300.0   8 2227.0 0.5598 5857.0, 22641.0 -1.0
C57BL/6J f 64703.0 11169.0   7 4221.0 0.1726 54759.0, 87402.0 -0.18
C57BL/6J m 46290.0 11029.0   5 4932.0 0.2383 30669.0, 60064.0 -0.22
CAST/EiJ f 144171.0 40419.0   7 15277.0 0.2804 94899.0, 222266.0 1.04
CAST/EiJ m 114452.0 50560.0   7 19110.0 0.4418 60074.0, 188048.0 1.3
DBA/2J f 38361.0 15448.0   3 8919.0 0.4027 21411.0, 51648.0 -0.58
DBA/2J m 47598.0 44570.0   2   31515.0 0.9364 16083.0, 79114.0 -0.19
NOD/ShiLtJ f 94927.0 54336.0   4 27168.0 0.5724 62894.0, 176061.0 0.29
NOD/ShiLtJ m 67821.0 30928.0   5 13831.0 0.456 26615.0, 99421.0 0.26
NZO/HlLtJ f 9126.0 5058.0   9 1686.0 0.5543 1741.0, 19103.0 -1.02
NZO/HlLtJ m 5412.0 2905.0   9 968.3 0.5367 1818.0, 9802.0 -1.13
PWK/PhJ f 144384.0 27164.0   8 9604.0 0.1881 112783.0, 188499.0 1.04
PWK/PhJ m 117299.0 54330.0   7 20535.0 0.4632 72460.0, 232876.0 1.37
WSB/EiJ f 173632.0 45024.0   7 17017.0 0.2593 127745.0, 246981.0 1.48
WSB/EiJ m 90954.0 16634.0   7 6287.0 0.1829 70279.0, 120069.0 0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3559.601625 10050.7842321685 23505.0558260253 -16385.8525760253
129S1/SvImJ m 2500.5625 10050.7842321685 22446.0167010254 -17444.8917010254
A/J f 13225.0 12713.3481778236 38454.2256967256 -12004.2256967256
A/J m 11253.25 10050.7842321685 31198.7042010254 -8692.2042010254
C57BL/6J f 64703.1428571429 10744.7403043326 86025.7302982366 43380.5554160492
C57BL/6J m 46290.4 12713.3481778236 71519.6256967256 21061.1743032744
CAST/EiJ f 144171.4285714285 10744.7403043326 165494.0160125222 122848.8411303348
CAST/EiJ m 114452.4285714284 10744.7403043326 135775.0160125221 93129.8411303347
DBA/2J f 38360.6666666665 16412.8619224157 70931.456987042 5789.8763462911
DBA/2J m 47598.4999999999 20101.568464337 87489.4084020506 7707.5915979491
NOD/ShiLtJ f 94927.0000000002 14213.9553736183 123134.1318387817 66719.8681612187
NOD/ShiLtJ m 67821.2000000002 12713.3481778236 93050.4256967258 42591.9743032746
NZO/HlLtJ f 9125.6666666666 9475.9702490789 27930.4212258542 -9679.087892521
NZO/HlLtJ m 5411.7777777777 9475.9702490789 24216.5323369654 -13392.97678141
PWK/PhJ f 144383.5 10050.7842321685 164328.9542010254 124438.0457989747
PWK/PhJ m 117299.4285714286 10744.7403043326 138622.0160125223 95976.8411303349
WSB/EiJ f 173632.1428571429 10744.7403043326 194954.7302982366 152309.5554160492
WSB/EiJ m 90953.5714285714 10744.7403043326 112276.1588696651 69630.9839874777


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3030.0820625 7106.9776868092 17133.6479818907 -11073.4838568907
A/J both 12239.125 8103.2013052277 28319.664267555 -3841.414267555
C57BL/6J both 55496.7714285714 8322.8400516008 72013.1766400529 38980.36621709
CAST/EiJ both 129311.9285714284 7597.678731282 144389.2747434689 114234.582399388
DBA/2J both 42979.5833333332 12975.5066491709 68729.0539843712 17230.1126822952
NOD/ShiLtJ both 81374.1000000002 9535.0111333677 100296.0192725445 62452.180727456
NZO/HlLtJ both 7268.7222222222 6700.5228214456 20565.6916895724 -6028.2472451281
PWK/PhJ both 130841.4642857143 7356.4207990224 145440.0419430435 116242.8866283851
WSB/EiJ both 132292.8571428572 7597.678731282 147370.2033148976 117215.5109708167




  GWAS USING LINEAR MIXED MODELS