Project measure / variable:   CSNA03   dist_f30_cocaine_in_d12

ID, description, units MPD:90373   dist_f30_cocaine_in_d12   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 12  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 12



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means6138.0   cm 6214.0   cm
Median of the strain means6334.0   cm 6846.0   cm
SD of the strain means± 4284.0 ± 3383.0
Coefficient of variation (CV)0.698 0.5444
Min–max range of strain means789.2   –   12314.0   cm 1458.0   –   11390.0   cm
Mean sample size per strain6.1   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6970458.2756 6970458.2756 0.8151 0.3687
strain 8 1640610993.7435 205076374.2179 23.9794 < 0.0001
sex:strain 8 78243949.1787 9780493.6473 1.1436 0.3408
Residuals 104 889426210.9332 8552175.1051


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 789.2 1391.0   6 567.8 1.7623 -1.25
129S1/SvImJ m 1629.0 1233.0   6 503.2 0.7566 317.4, 2967.0 -1.36
A/J f 2352.0 929.7   12 268.4 0.3952 720.3, 3657.0 -0.88
A/J m 2895.0 1365.0   12 394.0 0.4715 693.3, 5076.0 -0.98
C57BL/6J f 7304.0 1518.0   5 678.7 0.2078 4895.0, 8737.0 0.27
C57BL/6J m 6205.0 1253.0   7 473.5 0.2019 5111.0, 8490.0 0.0
C57BL/6NJ f 1762.0 0.0   1   0.0 0.0 1762.0, 1762.0 -1.02
C57BL/6NJ m 5406.0 0.0   1   0.0 0.0 5406.0, 5406.0 -0.24
CAST/EiJ f 12314.0 4919.0   6 2008.0 0.3995 7144.0, 20890.0 1.44
CAST/EiJ m 8205.0 1181.0   5 528.0 0.1439 6674.0, 9789.0 0.59
DBA/2J f 5364.0 2252.0   3 1300.0 0.4199 3665.0, 7919.0 -0.18
DBA/2J m 7488.0 3458.0   4 1729.0 0.4618 4289.0, 12294.0 0.38
NOD/ShiLtJ f 10599.0 3184.0   6 1300.0 0.3004 6834.0, 16099.0 1.04
NOD/ShiLtJ m 11390.0 4575.0   6 1868.0 0.4016 5470.0, 18221.0 1.53
NZO/HlLtJ f 1737.0 553.4   6 225.9 0.3186 795.7, 2370.0 -1.03
NZO/HlLtJ m 1458.0 355.5   7 134.4 0.2438 955.3, 1937.0 -1.41
PWK/PhJ f 9392.0 3131.0   9 1044.0 0.3334 4319.0, 13552.0 0.76
PWK/PhJ m 9880.0 5660.0   8 2001.0 0.5729 5642.0, 23237.0 1.08
WSB/EiJ f 9763.0 5304.0   7 2005.0 0.5433 4394.0, 20094.0 0.85
WSB/EiJ m 7582.0 1907.0   7 720.8 0.2515 4426.0, 10251.0 0.4


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 789.1543333334 1193.8854708561 3156.6740243646 -1578.3653576979
129S1/SvImJ m 1629.1666666667 1193.8854708561 3996.6863576979 -738.3530243646
A/J f 2352.3583333333 844.2045124024 4026.4475614542 678.2691052125
A/J m 2894.775 844.2045124024 4568.8642281209 1220.6857718791
C57BL/6J f 7304.4 1307.8360069311 9897.887880231 4710.912119769
C57BL/6J m 6204.8571428571 1105.323165745 8396.7544594212 4012.9598262931
CAST/EiJ f 12313.6666666667 1193.8854708561 14681.1863576979 9946.1469756354
CAST/EiJ m 8205.0 1307.8360069311 10798.487880231 5611.512119769
DBA/2J f 5364.3333333333 1688.4090248048 8712.5117895751 2016.1548770916
DBA/2J m 7487.75 1462.2051074599 10387.3575995091 4588.1424004909
NOD/ShiLtJ f 10598.8333333333 1193.8854708561 12966.3530243646 8231.3136423021
NOD/ShiLtJ m 11390.1666666667 1193.8854708561 13757.6863576979 9022.6469756354
NZO/HlLtJ f 1737.1166666667 1193.8854708561 4104.6363576979 -630.4030243646
NZO/HlLtJ m 1458.4714285714 1105.323165745 3650.3687451355 -733.4258879926
PWK/PhJ f 9392.0 974.8034049733 11325.0717330061 7458.9282669939
PWK/PhJ m 9879.625 1033.9351469705 11929.9571963929 7829.292803607
WSB/EiJ f 9763.4285714286 1105.323165745 11955.3258879926 7571.5312548645
WSB/EiJ m 7581.8571428571 1105.323165745 9773.7544594212 5389.9598262931


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1209.1605 844.2045124024 2883.2497281209 -464.9287281209
A/J both 2623.5666666667 596.942735428 3807.3265121823 1439.806821151
C57BL/6J both 6754.6285714286 856.1796426215 8452.4649321584 5056.7922106987
CAST/EiJ both 10259.3333333333 885.4091622728 12015.1329284128 8503.5337382538
DBA/2J both 6426.0416666667 1116.7775977477 8640.6535517366 4211.4297815967
NOD/ShiLtJ both 10994.5 844.2045124024 12668.5892281209 9320.4107718791
NZO/HlLtJ both 1597.794047619 813.4958233227 3210.9867929057 -15.3986976676
PWK/PhJ both 9635.8125 710.5039701663 11044.7685355555 8226.8564644445
WSB/EiJ both 8672.6428571429 781.5815059008 10222.5483133499 7122.7374009358




  GWAS USING LINEAR MIXED MODELS