Project measure / variable:   CSNA03   dist_f30_cocaine_in_d11

ID, description, units MPD:90367   dist_f30_cocaine_in_d11   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 11  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 11



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means7043.0   cm 6973.0   cm
Median of the strain means7406.0   cm 7060.0   cm
SD of the strain means± 4908.0 ± 4242.0
Coefficient of variation (CV)0.6969 0.6084
Min–max range of strain means1195.0   –   15181.0   cm 1083.0   –   13783.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11985306.5172 11985306.5172 1.1666 0.2826
strain 8 2279106966.987 284888370.8734 27.7299 < 0.0001
sex:strain 8 52431552.6584 6553944.0823 0.6379 0.7442
Residuals 105 1078737800.7571 10273693.3405


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1195.0 2391.0   6 976.2 2.0016 -1.19
129S1/SvImJ m 1083.0 758.2   6 309.5 0.7004 -1.39
A/J f 2460.0 1035.0   11 311.9 0.4206 432.2, 4223.0 -0.93
A/J m 3058.0 1532.0   12 442.3 0.5011 431.6, 5605.0 -0.92
C57BL/6J f 6003.0 3365.0   6 1374.0 0.5605 -0.21
C57BL/6J m 6309.0 1418.0   7 535.8 0.2247 4841.0, 8974.0 -0.16
C57BL/6NJ f 2686.0 0.0   1   0.0 0.0 2686.0, 2686.0 -0.89
C57BL/6NJ m 5478.0 0.0   1   0.0 0.0 5478.0, 5478.0 -0.35
CAST/EiJ f 15181.0 5213.0   6 2128.0 0.3434 9690.0, 23563.0 1.66
CAST/EiJ m 13783.0 10250.0   5 4584.0 0.7437 7397.0, 31972.0 1.61
DBA/2J f 8809.0 1756.0   3 1014.0 0.1993 7595.0, 10822.0 0.36
DBA/2J m 10215.0 3431.0   4 1715.0 0.3359 6863.0, 14842.0 0.76
NOD/ShiLtJ f 11782.0 2517.0   6 1028.0 0.2136 7862.0, 15048.0 0.97
NOD/ShiLtJ m 11114.0 2778.0   6 1134.0 0.25 8120.0, 16161.0 0.98
NZO/HlLtJ f 1857.0 750.9   6 306.6 0.4043 868.6, 3006.0 -1.06
NZO/HlLtJ m 1577.0 769.5   7 290.8 0.4878 578.8, 2565.0 -1.27
PWK/PhJ f 9103.0 2252.0   9 750.5 0.2474 6522.0, 12975.0 0.42
PWK/PhJ m 9300.0 2738.0   9 912.7 0.2944 7322.0, 15736.0 0.55
WSB/EiJ f 11358.0 4394.0   7 1661.0 0.3868 6512.0, 20347.0 0.88
WSB/EiJ m 7810.0 2928.0   7 1107.0 0.375 4064.0, 12331.0 0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1194.6666666667 1308.5420220322 3789.2637743547 -1399.9304410213
129S1/SvImJ m 1082.6333333333 1308.5420220322 3677.2304410213 -1511.9637743547
A/J f 2459.7454545455 966.4223310063 4375.9824134013 543.5084956896
A/J m 3057.9666666667 925.2789372465 4892.6238759599 1223.3094573735
C57BL/6J f 6003.0 1308.5420220322 8597.597107688 3408.402892312
C57BL/6J m 6309.0 1211.4745053944 8711.1301531093 3906.8698468907
CAST/EiJ f 15181.0 1308.5420220322 17775.597107688 12586.402892312
CAST/EiJ m 13783.2 1433.4359658209 16625.4387270367 10940.9612729632
DBA/2J f 8809.0 1850.557874493 12478.3144185864 5139.6855814136
DBA/2J m 10215.0 1602.6301304843 13392.7195009683 7037.2804990317
NOD/ShiLtJ f 11781.5 1308.5420220322 14376.097107688 9186.902892312
NOD/ShiLtJ m 11114.0 1308.5420220322 13708.597107688 8519.402892312
NZO/HlLtJ f 1857.2666666667 1308.5420220321 4451.8637743547 -737.3304410213
NZO/HlLtJ m 1577.4142857143 1211.4745053944 3979.5444388236 -824.715867395
PWK/PhJ f 9102.6666666667 1068.4200869895 11221.1463339789 6984.1869993544
PWK/PhJ m 9300.1111111111 1068.4200869895 11418.5907784233 7181.6314437989
WSB/EiJ f 11357.8571428571 1211.4745053944 13759.9872959664 8955.7269897479
WSB/EiJ m 7809.7142857143 1211.4745053944 10211.8444388236 5407.584132605


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1138.65 925.2789372465 2973.3072092932 -696.0072092932
A/J both 2758.8560606061 668.9755663661 4085.3110313925 1432.4010898196
C57BL/6J both 6156.0 891.6210939413 7923.9199235047 4388.0800764953
CAST/EiJ both 14482.1 970.4407364096 16406.3047144658 12557.8952855341
DBA/2J both 9512.0 1224.0289806602 11939.0233584208 7084.9766415792
NOD/ShiLtJ both 11447.75 925.2789372465 13282.4072092932 9613.0927907068
NZO/HlLtJ both 1717.3404761905 891.6210939413 3485.2603996952 -50.5794473142
PWK/PhJ both 9201.3888888889 755.4870886662 10699.3802274512 7703.3975503266
WSB/EiJ both 9583.7857142857 856.641837999 11282.348234842 7885.2231937295




  GWAS USING LINEAR MIXED MODELS