Project measure / variable:   CSNA03   dist_f30_cocaine_in_d9

ID, description, units MPD:90361   dist_f30_cocaine_in_d9   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 9  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means6872.0   cm 6402.0   cm
Median of the strain means6930.0   cm 7051.0   cm
SD of the strain means± 4173.0 ± 3657.0
Coefficient of variation (CV)0.6072 0.5712
Min–max range of strain means651.6   –   13358.0   cm 795.6   –   11167.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7123597.6115 7123597.6115 1.0563 0.3064
strain 8 1767760554.01 220970069.2512 32.7664 < 0.0001
sex:strain 8 89812027.1708 11226503.3964 1.6647 0.1157
Residuals 105 708098889.1823 6743798.9446


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 651.6 1222.0   6 498.8 1.875 -1.49
129S1/SvImJ m 795.6 504.3   6 205.9 0.6338 103.1, 1484.0 -1.53
A/J f 2630.0 1446.0   12 417.5 0.5499 610.4, 5367.0 -1.02
A/J m 3019.0 1933.0   12 558.0 0.6404 -0.93
C57BL/6J f 6739.0 1694.0   5 757.6 0.2514 3889.0, 8285.0 -0.03
C57BL/6J m 6599.0 936.7   7 354.1 0.1419 5719.0, 8031.0 0.05
C57BL/6NJ f 5753.0 0.0   1   0.0 0.0 5753.0, 5753.0 -0.27
C57BL/6NJ m 4564.0 0.0   1   0.0 0.0 4564.0, 4564.0 -0.5
CAST/EiJ f 13358.0 6284.0   6 2565.0 0.4704 7946.0, 24656.0 1.55
CAST/EiJ m 8576.0 1515.0   5 677.3 0.1766 6672.0, 10876.0 0.59
DBA/2J f 7120.0 499.1   3 288.2 0.0701 6756.0, 7689.0 0.06
DBA/2J m 9980.0 1530.0   4 765.1 0.1533 8365.0, 11617.0 0.98
NOD/ShiLtJ f 11700.0 2752.0   6 1123.0 0.2352 7536.0, 16137.0 1.16
NOD/ShiLtJ m 11167.0 3098.0   6 1265.0 0.2774 8160.0, 16535.0 1.3
NZO/HlLtJ f 2215.0 1340.0   6 547.2 0.605 797.9, 4437.0 -1.12
NZO/HlLtJ m 1901.0 915.9   7 346.2 0.4818 1080.0, 3530.0 -1.23
PWK/PhJ f 9136.0 2228.0   9 742.8 0.2439 5794.0, 12167.0 0.54
PWK/PhJ m 9919.0 3920.0   9 1307.0 0.3952 5742.0, 16668.0 0.96
WSB/EiJ f 9419.0 2862.0   7 1082.0 0.3039 5583.0, 14481.0 0.61
WSB/EiJ m 7503.0 3931.0   7 1486.0 0.5239 3400.0, 15447.0 0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 651.5833333333 1060.1728589082 2753.7102708395 -1450.5436041728
129S1/SvImJ m 795.6 1060.1728589082 2897.7269375062 -1306.5269375062
A/J f 2629.7333333333 749.6554177639 4116.1615457589 1143.3051209078
A/J m 3018.725 749.6554177639 4505.1532124255 1532.2967875745
C57BL/6J f 6738.6 1161.3611793575 9041.3646848228 4435.8353151772
C57BL/6J m 6599.1428571429 981.5293420106 8545.3342281594 4652.9514861263
CAST/EiJ f 13357.6666666666 1060.1728589082 15459.7936041728 11255.5397291605
CAST/EiJ m 8575.6 1161.3611793575 10878.3646848227 6272.8353151772
DBA/2J f 7120.0 1499.3108355279 10092.856424851 4147.1435751489
DBA/2J m 9980.5 1298.4412717364 12555.0691857248 7405.9308142752
NOD/ShiLtJ f 11699.8333333333 1060.1728589082 13801.9602708395 9597.7063958272
NOD/ShiLtJ m 11167.3333333334 1060.1728589082 13269.4602708395 9065.2063958272
NZO/HlLtJ f 2215.4833333333 1060.1728589082 4317.6102708395 113.3563958272
NZO/HlLtJ m 1901.0 981.5293420106 3847.1913710165 -45.1913710165
PWK/PhJ f 9136.4444444444 865.6275144909 10852.8239015943 7420.0649872946
PWK/PhJ m 9919.3333333333 865.6275144909 11635.7127904832 8202.9538761835
WSB/EiJ f 9418.7142857143 981.5293420106 11364.9056567308 7472.5229146977
WSB/EiJ m 7503.2857142857 981.5293420106 9449.4770853022 5557.0943432692


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 723.5916666667 749.6554177639 2210.0198790922 -762.8365457589
A/J both 2824.2291666667 530.0864294541 3875.2926354198 1773.1656979136
C57BL/6J both 6668.8714285714 760.2893590842 8176.3847822674 5161.3580748755
CAST/EiJ both 10966.6333333333 786.2452352295 12525.6123946949 9407.6542719717
DBA/2J both 8550.25 991.7009021978 10516.6096959141 6583.8903040859
NOD/ShiLtJ both 11433.5833333334 749.6554177639 12920.0115457589 9947.1551209078
NZO/HlLtJ both 2058.2416666667 722.3860359934 3490.5997324107 625.8836009226
PWK/PhJ both 9527.8888888889 612.0910854782 10741.5524421288 8314.2253356489
WSB/EiJ both 8461.0 694.0460536692 9837.1651159325 7084.8348840675




  GWAS USING LINEAR MIXED MODELS