Project measure / variable:   CSNA03   dist_f30_cocaine_in_d5

ID, description, units MPD:90349   dist_f30_cocaine_in_d5   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 5  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means6704.0   cm 6345.0   cm
Median of the strain means6262.0   cm 6959.0   cm
SD of the strain means± 4649.0 ± 3858.0
Coefficient of variation (CV)0.6935 0.6081
Min–max range of strain means653.9   –   13943.0   cm 959.9   –   11590.0   cm
Mean sample size per strain6.2   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16171897.9983 16171897.9983 2.3582 0.1276
strain 8 2133220773.7921 266652596.724 38.8837 < 0.0001
sex:strain 8 39382520.3969 4922815.0496 0.7179 0.6753
Residuals 106 726915747.0271 6857695.7267


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 653.9 1303.0   6 531.9 1.9923 -1.3
129S1/SvImJ m 959.9 616.7   6 251.8 0.6424 378.2, 2062.0 -1.4
A/J f 2403.0 1262.0   12 364.4 0.5253 387.8, 4108.0 -0.93
A/J m 2292.0 1446.0   12 417.4 0.6309 76.81, 5958.0 -1.05
C57BL/6J f 7022.0 1545.0   6 630.8 0.2201 3982.0, 8143.0 0.07
C57BL/6J m 6185.0 1480.0   7 559.3 0.2392 3309.0, 7845.0 -0.04
C57BL/6NJ f 4064.0 0.0   1   0.0 0.0 4064.0, 4064.0 -0.57
C57BL/6NJ m 4514.0 0.0   1   0.0 0.0 4514.0, 4514.0 -0.47
CAST/EiJ f 13943.0 6053.0   6 2471.0 0.4341 9003.0, 25535.0 1.56
CAST/EiJ m 11590.0 4766.0   5 2131.0 0.4112 6583.0, 18975.0 1.36
DBA/2J f 5503.0 2297.0   3 1326.0 0.4174 3644.0, 8071.0 -0.26
DBA/2J m 7733.0 2843.0   4 1421.0 0.3676 4211.0, 11149.0 0.36
NOD/ShiLtJ f 11501.0 1966.0   6 802.6 0.1709 7783.0, 13320.0 1.03
NOD/ShiLtJ m 10931.0 2793.0   6 1140.0 0.2556 7308.0, 14689.0 1.19
NZO/HlLtJ f 1336.0 444.6   6 181.5 0.3329 785.6, 1864.0 -1.15
NZO/HlLtJ m 1616.0 681.9   7 257.7 0.4219 911.5, 2729.0 -1.23
PWK/PhJ f 9701.0 2213.0   9 737.6 0.2281 5872.0, 12877.0 0.64
PWK/PhJ m 9072.0 2842.0   9 947.2 0.3132 5309.0, 13978.0 0.71
WSB/EiJ f 10913.0 4444.0   7 1680.0 0.4072 6459.0, 18258.0 0.91
WSB/EiJ m 8558.0 3101.0   7 1172.0 0.3623 4176.0, 13293.0 0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 653.9333333333 1069.0880636218 2773.504400856 -1465.6377341893
129S1/SvImJ m 959.9166666667 1069.0880636218 3079.4877341893 -1159.654400856
A/J f 2402.975 755.9594194725 3901.7380750521 904.2119249479
A/J m 2291.7008333333 755.9594194725 3790.4639083854 792.9377582812
C57BL/6J f 7021.6666666667 1069.0880636218 9141.2377341893 4902.095599144
C57BL/6J m 6185.0 989.7832177279 8147.3414972089 4222.6585027912
CAST/EiJ f 13943.1666666667 1069.0880636218 16062.7377341894 11823.595599144
CAST/EiJ m 11590.2 1171.1272968103 13912.073771835 9268.3262281651
DBA/2J f 5503.0 1511.9188389451 8500.5261501042 2505.4738498958
DBA/2J m 7732.75 1309.3601229867 10328.6837944984 5136.8162055016
NOD/ShiLtJ f 11501.1666666667 1069.0880636218 13620.7377341893 9381.595599144
NOD/ShiLtJ m 10931.0 1069.0880636218 13050.5710675227 8811.4289324773
NZO/HlLtJ f 1335.5166666667 1069.0880636218 3455.0877341893 -784.054400856
NZO/HlLtJ m 1616.2142857143 989.7832177279 3578.5557829231 -346.1272114946
PWK/PhJ f 9700.8888888889 872.9067486578 11431.5114185545 7970.2663592233
PWK/PhJ m 9072.4444444444 872.9067486578 10803.06697411 7341.8219147789
WSB/EiJ f 10912.7142857143 989.7832177279 12875.0557829231 8950.3727885054
WSB/EiJ m 8558.4285714286 989.7832177279 10520.7700686374 6596.0870742197


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 806.925 755.9594194725 2305.6880750521 -691.8380750521
A/J both 2347.3379166667 534.5440318109 3407.123450428 1287.5523829053
C57BL/6J both 6603.3333333333 728.4607240398 8047.5775701184 5159.0890965483
CAST/EiJ both 12766.6833333334 792.8569280004 14338.5993077587 11194.767358908
DBA/2J both 6617.875 1000.0403125905 8600.5521853971 4635.1978146029
NOD/ShiLtJ both 11216.0833333333 755.9594194725 12714.8464083854 9717.3202582812
NZO/HlLtJ both 1475.8654761905 728.4607240398 2920.1097129755 31.6212394055
PWK/PhJ both 9386.6666666667 617.2382813194 10610.4015930674 8162.9317402659
WSB/EiJ both 9735.5714285714 699.8824251601 11123.1564082516 8347.9864488913




  GWAS USING LINEAR MIXED MODELS