Project measure / variable:   CSNA03   dist_f30_cocaine_in_d3

ID, description, units MPD:90343   dist_f30_cocaine_in_d3   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 3  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means6259.0   cm 5575.0   cm
Median of the strain means5925.0   cm 5654.0   cm
SD of the strain means± 4316.0 ± 3374.0
Coefficient of variation (CV)0.6897 0.6051
Min–max range of strain means424.4   –   12992.0   cm 743.2   –   10234.0   cm
Mean sample size per strain6.0   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 22285236.9681 22285236.9681 4.1588 0.044
strain 8 1774996814.0498 221874601.7562 41.4054 < 0.0001
sex:strain 8 58254593.3415 7281824.1677 1.3589 0.2234
Residuals 104 557293322.7042 5358589.6414


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 424.4 692.0   6 282.5 1.6306 -1.35
129S1/SvImJ m 743.2 779.2   6 318.1 1.0484 13.189, 2187.0 -1.43
A/J f 2268.0 1069.0   12 308.5 0.4712 473.8, 3558.0 -0.92
A/J m 2422.0 1309.0   12 378.0 0.5406 332.4, 5507.0 -0.93
C57BL/6J f 6854.0 552.7   5 247.2 0.0806 5988.0, 7374.0 0.14
C57BL/6J m 5672.0 810.6   7 306.4 0.1429 4275.0, 6468.0 0.03
C57BL/6NJ f 4996.0 0.0   1   0.0 0.0 4996.0, 4996.0 -0.29
C57BL/6NJ m 4583.0 0.0   1   0.0 0.0 4583.0, 4583.0 -0.29
CAST/EiJ f 12992.0 7531.0   6 3074.0 0.5796 8630.0, 27922.0 1.56
CAST/EiJ m 8296.0 1535.0   5 686.5 0.185 6706.0, 10702.0 0.81
DBA/2J f 4638.0 1774.0   2   1254.0 0.3825 3384.0, 5893.0 -0.38
DBA/2J m 5637.0 2667.0   4 1334.0 0.4732 2341.0, 8872.0 0.02
NOD/ShiLtJ f 10587.0 1771.0   6 723.2 0.1673 7642.0, 12587.0 1.0
NOD/ShiLtJ m 10234.0 2480.0   6 1013.0 0.2423 7480.0, 13294.0 1.38
NZO/HlLtJ f 916.2 437.2   6 178.5 0.4771 284.7, 1646.0 -1.24
NZO/HlLtJ m 1008.0 411.2   7 155.4 0.408 578.5, 1682.0 -1.35
PWK/PhJ f 9248.0 1437.0   9 478.9 0.1554 7110.0, 11491.0 0.69
PWK/PhJ m 8315.0 2436.0   9 811.9 0.2929 4813.0, 12469.0 0.81
WSB/EiJ f 9662.0 1933.0   7 730.6 0.2001 6949.0, 11918.0 0.79
WSB/EiJ m 8842.0 3240.0   7 1224.0 0.3664 5644.0, 15495.0 0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 424.4166666667 945.0387682865 2298.4640081608 -1449.6306748274
129S1/SvImJ m 743.1981666667 945.0387682865 2617.2455081608 -1130.8491748274
A/J f 2268.3166666667 668.2433215396 3593.4682501018 943.1650832316
A/J m 2422.1166666667 668.2433215396 3747.2682501018 1096.9650832316
C57BL/6J f 6854.0 1035.2381022148 8906.9160055378 4801.0839944622
C57BL/6J m 5671.7142857143 874.9358867439 7406.7449823948 3936.6835890337
CAST/EiJ f 12992.5 945.0387682865 14866.5473414941 11118.4526585059
CAST/EiJ m 8295.8 1035.2381022148 10348.7160055378 6242.8839944622
DBA/2J f 4638.5 1636.8551617945 7884.4452112572 1392.5547887429
DBA/2J m 5636.75 1157.4313847251 7931.9798702399 3341.5201297601
NOD/ShiLtJ f 10587.0 945.0387682865 12461.0473414941 8712.9526585059
NOD/ShiLtJ m 10234.0 945.0387682865 12108.0473414941 8359.9526585059
NZO/HlLtJ f 916.25 945.0387682865 2790.2973414941 -957.7973414941
NZO/HlLtJ m 1007.8 874.9358867439 2742.8306966805 -727.2306966805
PWK/PhJ f 9248.1111111111 771.6209231501 10778.2643579377 7717.9578642845
PWK/PhJ m 8314.6666666667 771.6209231501 9844.8199134933 6784.5134198401
WSB/EiJ f 9662.0 874.9358867439 11397.0306966806 7926.9693033195
WSB/EiJ m 8842.0 874.9358867439 10577.0306966805 7106.9693033195


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 583.8074166667 668.2433215396 1908.9590001018 -741.3441667684
A/J both 2345.2166666667 472.5193841433 3282.2403374137 1408.1929959196
C57BL/6J both 6262.8571428571 677.7224236717 7606.8061415376 4918.9081441767
CAST/EiJ both 10644.15 700.8595083613 12033.9807058734 9254.3192941266
DBA/2J both 5137.625 1002.3649823094 7125.3523751526 3149.8976248474
NOD/ShiLtJ both 10410.5 668.2433215396 11735.6515834351 9085.3484165649
NZO/HlLtJ both 962.025 643.9353770909 2238.9730174017 -314.9230174017
PWK/PhJ both 8781.3888888889 545.6183872648 9863.3706259746 7699.4071518032
WSB/EiJ both 9252.0 618.6730986201 10478.8519711896 8025.1480288104




  GWAS USING LINEAR MIXED MODELS