Project measure / variable:   CSNA03   dist_d5_d3_cont_in

ID, description, units MPD:90310   dist_d5_d3_cont_in   distance traveled, last 60 min (post-injection), Day 5 minus Day 3, saline control, founders   [cm]  
Data set, strains CSNA03   inbred w/CC8   9 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, last 60 min (post-injection), Day 5 minus Day 3, saline control, founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means395.0   cm -455.8   cm
Median of the strain means119.4   cm -124.1   cm
SD of the strain means± 1346.0 ± 1554.0
Coefficient of variation (CV)3.4086 -3.4089
Min–max range of strain means-2154.0   –   2805.0   cm -4157.0   –   1479.0   cm
Mean sample size per strain6.6   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 22152126.1855 22152126.1855 3.903 0.051
strain 8 124461662.1472 15557707.7684 2.7412 0.009
sex:strain 8 80842267.6902 10105283.4613 1.7805 0.09
Residuals 98 556208850.3505 5675600.5138


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -14.587 320.3   8 113.3 -21.961 -538.9, 550.6 -0.3
129S1/SvImJ m 118.4 303.5   8 107.3 2.563 -234.7, 671.0 0.37
A/J f -201.3 1449.0   7 547.6 -7.1967 -3460.0, 721.3 -0.44
A/J m -80.87 464.2   8 164.1 -5.74 -771.9, 563.1 0.24
C57BL/6J f 620.7 1879.0   7 710.1 3.0269 -2047.0, 3858.0 0.17
C57BL/6J m -157.0 3472.0   5 1553.0 -22.114 -2776.0, 5682.0 0.19
CAST/EiJ f 2805.0 4019.0   6 1641.0 1.4326 -2843.0, 8786.0 1.79
CAST/EiJ m 1479.0 3157.0   6 1289.0 2.1336 -1621.0, 7204.0 1.25
DBA/2J f 1406.0 785.4   3 453.4 0.5586 543.1, 2079.0 0.75
DBA/2J m 487.8 981.8   2   694.2 2.013 -206.5, 1182.0 0.61
NOD/ShiLtJ f -2154.0 4099.0   5 1833.0 -1.903 -5535.0, 4709.0 -1.89
NOD/ShiLtJ m -938.6 2174.0   5 972.2 -2.316 -4223.0, 1398.0 -0.31
NZO/HlLtJ f -15.968 279.9   9 93.31 -17.5304 -359.1, 335.7 -0.31
NZO/HlLtJ m -124.1 322.3   9 107.4 -2.5965 -781.8, 205.4 0.21
PWK/PhJ f 119.4 2044.0   8 722.7 17.1141 -3370.0, 2868.0 -0.2
PWK/PhJ m -729.4 3308.0   7 1250.0 -4.5354 -7374.0, 2182.0 -0.18
WSB/EiJ f 989.5 3845.0   6 1570.0 3.8863 -4018.0, 6224.0 0.44
WSB/EiJ m -4157.0 3701.0   7 1399.0 -0.8901 -9764.0, 498.2 -2.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -14.587 842.2885872565 1656.9072887145 -1686.0812887145
129S1/SvImJ m 118.4 842.2885872565 1789.8942887145 -1553.0942887145
A/J f -201.3285714286 900.4443755153 1585.5739863768 -1988.231129234
A/J m -80.873 842.2885872565 1590.6212887145 -1752.3672887145
C57BL/6J f 620.6714285714 900.4443755153 2407.5739863768 -1166.231129234
C57BL/6J m -157.016 1065.4201531584 1957.2756193203 -2271.3076193203
CAST/EiJ f 2805.1833333333 972.5910851758 4735.2586884098 875.1079782569
CAST/EiJ m 1479.45 972.5910851758 3409.5253550764 -450.6253550764
DBA/2J f 1406.0333333333 1375.4515032988 4135.5720768845 -1323.5054102178
DBA/2J m 487.75 1684.577174513 3830.7385774289 -2855.2385774289
NOD/ShiLtJ f -2153.8 1065.4201531584 -39.5083806797 -4268.0916193203
NOD/ShiLtJ m -938.64 1065.4201531584 1175.6516193203 -3052.9316193203
NZO/HlLtJ f -15.9677777778 794.1172956868 1559.932150575 -1591.8677061306
NZO/HlLtJ m -124.1111111111 794.1172956868 1451.7888172417 -1700.0110394639
PWK/PhJ f 119.445 842.2885872565 1790.9392887145 -1552.0492887145
PWK/PhJ m -729.4014285714 900.4443755153 1057.501129234 -2516.3039863768
WSB/EiJ f 989.495 972.5910851758 2919.5703550764 -940.5803550764
WSB/EiJ m -4157.3571428571 900.4443755153 -2370.4545850517 -5944.2597006626


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 51.9065 595.5879717651 1233.8314462646 -1130.0184462646
A/J both -141.1007857143 616.4921203105 1082.3077630028 -1364.5093344314
C57BL/6J both 231.8277142857 697.4812141114 1615.9564838209 -1152.3010552494
CAST/EiJ both 2142.3166666667 687.7257516494 3507.0860384423 777.5472948911
DBA/2J both 946.8916666667 1087.3898903817 3104.7815144906 -1210.9981811573
NOD/ShiLtJ both -1546.22 753.3658151111 -51.1900585727 -3041.2499414273
NZO/HlLtJ both -70.0394444444 561.5257248377 1044.2900813652 -1184.3689702541
PWK/PhJ both -304.9782142857 616.4921203105 918.4303344314 -1528.3867630028
WSB/EiJ both -1583.9310714286 662.7091164985 -268.8063979313 -2899.0557449258




  GWAS USING LINEAR MIXED MODELS