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Project measure / variable:   CSNA03   center_time_OFT_in

ID, description, units MPD:90124   center_time_OFT_in   time in center, 60 min test (OFT), founders   [s]  
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 4-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - time in center, 60 min test (OFT), founders



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means82.55   s 77.82   s
Median of the strain means73.72   s 81.03   s
SD of the strain means± 69.18 ± 56.99
Coefficient of variation (CV)0.838 0.7324
Min–max range of strain means6.6492   –   215.9   s 7.3209   –   193.7   s
Mean sample size per strain43.5   mice 42.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 14543.8769 14543.8769 4.962 0.0262
strain 9 3259168.0564 362129.784 123.5495 < 0.0001
sex:strain 9 68190.8617 7576.7624 2.585 0.0061
Residuals 841 2465012.7114 2931.0496


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.6492 19.319   48 2.7885 2.9055 0.04, 123.0 -1.1
129S1/SvImJ m 10.766 21.366   49 3.0523 1.9845 0.04, 93.68 -1.18
A/J f 16.302 35.792   59 4.6597 2.1956 0.04, 144.4 -0.96
A/J m 18.74 42.597   61 5.454 2.2731 0.08, 245.6 -1.04
C57BL/6J f 92.3 22.859   61 2.9267 0.2476 55.0, 155.9 0.14
C57BL/6J m 91.33 28.909   59 3.7637 0.3165 48.24, 217.9 0.24
C57BL/6NJ f 47.471 19.914   13 5.5233 0.4195 16.04, 75.92 -0.51
C57BL/6NJ m 79.39 54.25   13 15.048 0.6834 29.72, 208.2 0.03
CAST/EiJ f 161.4 144.1   33 25.077 0.8924 20.64, 801.5 1.14
CAST/EiJ m 106.2 47.706   30 8.7098 0.4493 55.0, 312.4 0.5
DBA/2J f 55.13 25.086   24 5.1207 0.455 -0.4
DBA/2J m 68.45 27.557   25 5.5115 0.4026 8.76, 132.0 -0.16
NOD/ShiLtJ f 215.9 109.5   47 15.973 0.5072 130.7, 808.5 1.93
NOD/ShiLtJ m 193.7 62.94   44 9.488 0.3249 93.76, 402.3 2.03
NZO/HlLtJ f 10.547 11.269   47 1.6437 1.0684 0.08, 59.6 -1.04
NZO/HlLtJ m 7.3209 3.56   46 0.52489 0.4863 1.12, 18.5 -1.24
PWK/PhJ f 100.8 29.753   48 4.2944 0.2951 51.4, 210.8 0.26
PWK/PhJ m 82.68 30.338   47 4.4252 0.3669 0.08, 174.0 0.09
WSB/EiJ f 119.0 60.0   55 8.09 0.5042 54.28, 452.9 0.53
WSB/EiJ m 119.6 83.2   52 11.538 0.6955 59.52, 487.9 0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.6491666667 7.8143159188 21.9870180709 -8.6886847375
129S1/SvImJ m 10.766122449 7.7341669701 25.9466583981 -4.4144135002
A/J f 16.3015254237 7.0483194263 30.135887527 2.4671633204
A/J m 18.7395081967 6.9318102541 32.3451874072 5.1338289862
C57BL/6J f 92.3021311475 6.9318102541 105.907810358 78.6964519371
C57BL/6J m 91.3294915254 7.0483194263 105.1638536287 77.4951294221
C57BL/6NJ f 47.4707692308 15.0155037759 76.9430311751 17.9985072865
C57BL/6NJ m 79.3892307692 15.0155037759 108.8614927135 49.9169688249
CAST/EiJ f 161.4260606061 9.4244195985 179.9242054053 142.9279158068
CAST/EiJ m 106.1793333333 9.8844146638 125.5803512735 86.7783153931
DBA/2J f 55.13 11.051111553 76.8209974735 33.4390025265
DBA/2J m 68.4472 10.8278337582 89.6999503288 47.1944496712
NOD/ShiLtJ f 215.8829787234 7.8970093954 231.3831399535 200.3828174933
NOD/ShiLtJ m 193.7127272727 8.1617867882 209.7325905918 177.6928639537
NZO/HlLtJ f 10.5472340426 7.8970093954 26.0473952727 -4.9529271876
NZO/HlLtJ m 7.3208695652 7.9823849511 22.988604976 -8.3468658456
PWK/PhJ f 100.834375 7.8143159188 116.1722264042 85.4965235958
PWK/PhJ m 82.6829787234 7.8970093954 98.1831399535 67.1828174933
WSB/EiJ f 118.9970909091 7.3001240305 133.3256922578 104.6684895604
WSB/EiJ m 119.6325 7.5077518879 134.3686309722 104.8963690278


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.7076445578 5.4972918787 19.4976672339 -2.0823781183
A/J both 17.5205168102 4.9428938926 27.222373354 7.8186602665
C57BL/6J both 91.8158113365 4.9428938926 101.5176678802 82.1139547927
C57BL/6NJ both 63.43 10.6175645429 84.2700362777 42.5899637223
CAST/EiJ both 133.8026969697 6.8286407508 147.2058762393 120.3995177001
DBA/2J both 61.7886 7.7357780871 76.9722982314 46.6049017686
NOD/ShiLtJ both 204.7978529981 5.6784135321 215.9433792185 193.6523267776
NZO/HlLtJ both 8.9340518039 5.6142948555 19.9537266069 -2.0856229992
PWK/PhJ both 91.7586768617 5.5548692754 102.6617118045 80.8556419189
WSB/EiJ both 119.3147954545 5.2358893531 129.5917401931 109.037850716




  GWAS USING LINEAR MIXED MODELS