Phenotype measure:   Neuner1   cfm_14mo_bin5

ID, description, units MPD:65984   cfm_14mo_bin5   percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test   [%]  5th 2 min
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test 5th 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means28.006   % 31.815   %
Median of the strain means25.453   % 25.89   %
SD of the strain means± 17.14 ± 17.032
Coefficient of variation (CV)0.612 0.5353
Min–max range of strain means2.675   –   70.73   % 2.23   –   63.81   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 639.4588 639.4588 2.164 0.1427
strain 25 70236.2454 2809.4498 9.5074 < 0.0001
sex:strain 25 12080.296 483.2118 1.6352 0.0334
Residuals 222 65600.9842 295.4999


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 47.269 26.801   27 5.1579 0.567 2.9, 100.0 0.91
(B6.5XFAD x B6)F1-Ntg f 51.22 17.645   9 5.8816 0.3445 21.87, 76.39 1.35
(B6.5XFAD x B6)F1-Ntg m 51.32 16.689   11 5.0319 0.3252 20.98, 76.34 1.15
(B6.5XFAD x BXD100)F1-ADtg f 9.49 5.8407   2   4.13 0.6155 5.36, 13.62 -1.08
(B6.5XFAD x BXD100)F1-ADtg m 18.561 20.778   7 7.8532 1.1194 -0.78
(B6.5XFAD x BXD100)F1-Ntg f 32.078 20.471   4 10.236 0.6382 14.51, 58.71 0.24
(B6.5XFAD x BXD100)F1-Ntg m 21.777 21.317   6 8.7028 0.9789 1.11, 59.91 -0.59
(B6.5XFAD x BXD14)F1-ADtg f 8.26 3.7901   2   2.68 0.4588 5.58, 10.94 -1.15
(B6.5XFAD x BXD14)F1-Ntg f 40.625 10.416   2   7.365 0.2564 33.26, 47.99 0.74
(B6.5XFAD x BXD16)F1-ADtg f 49.803 33.329   4 16.665 0.6692 4.46, 75.72 1.27
(B6.5XFAD x BXD22)F1-ADtg f 36.16 40.093   2   28.35 1.1088 7.81, 64.51 0.48
(B6.5XFAD x BXD22)F1-Ntg f 31.85 3.1537   2   2.23 0.099 29.62, 34.08 0.22
(B6.5XFAD x BXD32)F1-ADtg f 2.675 2.5244   2   1.785 0.9437 0.89, 4.46 -1.48
(B6.5XFAD x BXD32)F1-ADtg m 38.98 34.527   3 19.934 0.8858 6.25, 75.06 0.42
(B6.5XFAD x BXD32)F1-Ntg f 3.2733 0.93115   3 0.5376 0.2845 2.23, 4.02 -1.44
(B6.5XFAD x BXD32)F1-Ntg m 63.81 36.062   2   25.5 0.5652 38.31, 89.31 1.88
(B6.5XFAD x BXD42)F1-ADtg f 36.08 40.319   2   28.51 1.1175 7.57, 64.59 0.47
(B6.5XFAD x BXD42)F1-Ntg f 14.48 0.0   1   0.0 0.0 14.48, 14.48 -0.79
(B6.5XFAD x BXD44)F1-ADtg f 19.695 19.403   13 5.3815 0.9852 -0.48
(B6.5XFAD x BXD44)F1-ADtg m 18.062 13.552   8 4.7913 0.7503 -0.81
(B6.5XFAD x BXD44)F1-Ntg f 50.22 0.0   1   0.0 0.0 50.22, 50.22 1.3
(B6.5XFAD x BXD44)F1-Ntg m 31.677 5.4778   3 3.1626 0.1729 27.84, 37.95 -0.01
(B6.5XFAD x BXD51)F1-ADtg f 27.83 23.125   6 9.4406 0.8309 6.7, 58.8 -0.01
(B6.5XFAD x BXD51)F1-Ntg f 47.56 28.277   4 14.138 0.5945 7.59, 71.71 1.14
(B6.5XFAD x BXD55)F1-ADtg f 14.175 10.984   4 5.4919 0.7749 -0.81
(B6.5XFAD x BXD55)F1-Ntg f 16.045 13.852   2   9.795 0.8633 6.25, 25.84 -0.7
(B6.5XFAD x BXD56)F1-ADtg m 38.62 0.0   1   0.0 0.0 38.62, 38.62 0.4
(B6.5XFAD x BXD56)F1-Ntg f 25.445 35.985   2   25.445 1.4142 -0.15
(B6.5XFAD x BXD56)F1-Ntg m 2.23 0.0   1   0.0 0.0 2.23, 2.23 -1.74
(B6.5XFAD x BXD60)F1-ADtg f 21.743 8.5182   4 4.2591 0.3918 9.35, 28.51 -0.37
(B6.5XFAD x BXD60)F1-ADtg m 22.66 21.312   5 9.5312 0.9405 1.34, 58.26 -0.54
(B6.5XFAD x BXD60)F1-Ntg f 17.247 2.82   3 1.6281 0.1635 14.06, 19.42 -0.63
(B6.5XFAD x BXD61)F1-ADtg f 7.8414 5.4454   7 2.0582 0.6944 2.0, 15.4 -1.18
(B6.5XFAD x BXD61)F1-ADtg m 38.063 9.6299   3 5.5598 0.253 27.01, 44.64 0.37
(B6.5XFAD x BXD61)F1-Ntg f 36.744 19.575   5 8.7543 0.5327 8.91, 59.82 0.51
(B6.5XFAD x BXD61)F1-Ntg m 33.723 24.44   6 9.9774 0.7247 2.9, 58.48 0.11
(B6.5XFAD x BXD62)F1-ADtg f 4.9 5.1342   3 2.9642 1.0478 -1.35
(B6.5XFAD x BXD62)F1-ADtg m 25.89 23.363   2   16.52 0.9024 9.37, 42.41 -0.35
(B6.5XFAD x BXD62)F1-Ntg f 70.73 9.4387   3 5.4494 0.1335 62.58, 81.07 2.49
(B6.5XFAD x BXD62)F1-Ntg m 60.51 18.409   3 10.628 0.3042 39.29, 72.16 1.68
(B6.5XFAD x BXD65)F1-ADtg f 40.378 24.105   6 9.8408 0.597 10.94, 77.46 0.72
(B6.5XFAD x BXD65)F1-ADtg m 60.69 2.9981   2   2.12 0.0494 58.57, 62.81 1.7
(B6.5XFAD x BXD65)F1-Ntg f 60.33 17.605   8 6.2242 0.2918 33.71, 83.74 1.89
(B6.5XFAD x BXD65)F1-Ntg m 63.77 2.4254   2   1.715 0.038 62.05, 65.48 1.88
(B6.5XFAD x BXD66)F1-ADtg f 32.78 25.407   3 14.669 0.7751 8.46, 59.15 0.28
(B6.5XFAD x BXD66)F1-ADtg m 15.52 3.4855   5 1.5587 0.2246 10.94, 20.04 -0.96
(B6.5XFAD x BXD66)F1-Ntg f 21.87 0.0   1   0.0 0.0 21.87, 21.87 -0.36
(B6.5XFAD x BXD66)F1-Ntg m 24.683 11.38   3 6.5703 0.461 11.61, 32.37 -0.42
(B6.5XFAD x BXD68)F1-ADtg f 29.463 22.812   3 13.17 0.7742 4.91, 50.0 0.08
(B6.5XFAD x BXD68)F1-ADtg m 44.543 15.377   7 5.8119 0.3452 25.45, 63.92 0.75
(B6.5XFAD x BXD68)F1-Ntg f 55.15 25.949   10 8.2059 0.4705 11.16, 85.3 1.58
(B6.5XFAD x BXD68)F1-Ntg m 54.1 37.448   2   26.48 0.6922 27.62, 80.58 1.31
(B6.5XFAD x BXD69)F1-ADtg f 11.568 9.8841   6 4.0352 0.8544 0.89, 27.23 -0.96
(B6.5XFAD x BXD69)F1-ADtg m 23.814 12.714   5 5.6859 0.5339 3.56, 37.5 -0.47
(B6.5XFAD x BXD69)F1-Ntg f 33.017 5.7976   4 2.8988 0.1756 25.67, 38.62 0.29
(B6.5XFAD x BXD69)F1-Ntg m 20.18 12.251   6 5.0014 0.6071 0.89, 34.97 -0.68
(B6.5XFAD x BXD70)F1-ADtg f 36.75 0.0   1   0.0 0.0 36.75, 36.75 0.51
(B6.5XFAD x BXD70)F1-ADtg m 25.0 15.658   3 9.0402 0.6263 6.92, 34.15 -0.4
(B6.5XFAD x BXD70)F1-Ntg f 57.67 23.87   3 13.781 0.4139 36.83, 83.71 1.73
(B6.5XFAD x BXD70)F1-Ntg m 32.515 18.265   2   12.915 0.5617 19.6, 45.43 0.04
(B6.5XFAD x BXD75)F1-ADtg f 5.6225 11.245   4 5.6225 2.0 -1.31
(B6.5XFAD x BXD75)F1-ADtg m 13.317 6.41   4 3.205 0.4813 5.13, 20.71 -1.09
(B6.5XFAD x BXD75)F1-Ntg f 20.693 16.117   6 6.5797 0.7788 -0.43
(B6.5XFAD x BXD75)F1-Ntg m 14.7 0.0   1   0.0 0.0 14.7, 14.7 -1.0
(B6.5XFAD x BXD77)F1-ADtg f 9.65 16.714   3 9.65 1.7321 -1.07
(B6.5XFAD x BXD77)F1-ADtg m 22.673 11.883   3 6.8608 0.5241 9.82, 33.26 -0.54
(B6.5XFAD x BXD77)F1-Ntg f 24.689 14.811   10 4.6837 0.5999 5.13, 56.12 -0.19
(B6.5XFAD x BXD77)F1-Ntg m 21.818 13.449   6 5.4904 0.6164 10.04, 47.99 -0.59
(B6.5XFAD x BXD81)F1-ADtg f 9.25 7.1252   6 2.9088 0.7703 -1.09
(B6.5XFAD x BXD81)F1-Ntg f 25.46 23.1   5 10.331 0.9073 3.34, 63.25 -0.15
(B6.5XFAD x BXD87)F1-ADtg f 22.135 21.51   10 6.8019 0.9717 1.78, 76.84 -0.34
(B6.5XFAD x BXD87)F1-ADtg m 30.525 17.283   4 8.6414 0.5662 13.59, 53.23 -0.08
(B6.5XFAD x BXD87)F1-Ntg f 22.953 26.343   3 15.209 1.1477 0.89, 52.12 -0.29
(B6.5XFAD x BXD87)F1-Ntg m 58.8 0.0   1   0.0 0.0 58.8, 58.8 1.58
(B6.5XFAD x BXD89)F1-ADtg m 12.95 0.0   1   0.0 0.0 12.95, 12.95 -1.11
(B6.5XFAD x BXD89)F1-Ntg f 35.605 25.095   2   17.745 0.7048 17.86, 53.35 0.44
(B6.5XFAD x BXD89)F1-Ntg m 35.825 6.7812   2   4.795 0.1893 31.03, 40.62 0.24
(B6.5XFAD x BXD99)F1-ADtg f 53.23 0.0   1   0.0 0.0 53.23, 53.23 1.47
(B6.5XFAD x BXD99)F1-Ntg f 39.2 0.0   1   0.0 0.0 39.2, 39.2 0.65
(B6.5XFAD x D2)F1-ADtg f 8.6306 15.021   17 3.6431 1.7404 -1.13
(B6.5XFAD x D2)F1-ADtg m 7.42 10.638   8 3.761 1.4337 -1.43
(B6.5XFAD x D2)F1-Ntg f 12.044 12.369   12 3.5707 1.027 -0.93
(B6.5XFAD x D2)F1-Ntg m 17.525 12.237   4 6.1184 0.6983 1.12, 30.36 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 51.2167 5.73 62.5089 39.9244
(B6.5XFAD x B6)F1-Ntg m 51.3182 5.183 61.5324 41.104
(B6.5XFAD x BXD100)F1-ADtg f 9.49 12.1552 33.4444 -14.4644
(B6.5XFAD x BXD100)F1-ADtg m 18.5614 6.4973 31.3656 5.7572
(B6.5XFAD x BXD100)F1-Ntg f 32.0775 8.5951 49.0158 15.1392
(B6.5XFAD x BXD100)F1-Ntg m 21.7767 7.0178 35.6068 7.9466
(B6.5XFAD x BXD32)F1-ADtg f 2.675 12.1552 26.6294 -21.2794
(B6.5XFAD x BXD32)F1-ADtg m 38.98 9.9247 58.5387 19.4213
(B6.5XFAD x BXD32)F1-Ntg f 3.2733 9.9247 22.832 -16.2854
(B6.5XFAD x BXD32)F1-Ntg m 63.81 12.1552 87.7644 39.8556
(B6.5XFAD x BXD44)F1-ADtg f 19.6946 4.7677 29.0903 10.2989
(B6.5XFAD x BXD44)F1-ADtg m 18.0625 6.0776 30.0397 6.0853
(B6.5XFAD x BXD60)F1-ADtg f 21.7425 8.5951 38.6808 4.8042
(B6.5XFAD x BXD60)F1-ADtg m 22.66 7.6877 37.8101 7.5099
(B6.5XFAD x BXD61)F1-ADtg f 7.8414 6.4973 20.6456 -4.9628
(B6.5XFAD x BXD61)F1-ADtg m 38.0633 9.9247 57.622 18.5046
(B6.5XFAD x BXD61)F1-Ntg f 36.744 7.6877 51.8941 21.5939
(B6.5XFAD x BXD61)F1-Ntg m 33.7233 7.0178 47.5534 19.8932
(B6.5XFAD x BXD62)F1-ADtg f 4.9 9.9247 24.4587 -14.6587
(B6.5XFAD x BXD62)F1-ADtg m 25.89 12.1552 49.8444 1.9356
(B6.5XFAD x BXD62)F1-Ntg f 70.7267 9.9247 90.2854 51.168
(B6.5XFAD x BXD62)F1-Ntg m 60.5133 9.9247 80.072 40.9546
(B6.5XFAD x BXD65)F1-ADtg f 40.3783 7.0178 54.2084 26.5482
(B6.5XFAD x BXD65)F1-ADtg m 60.69 12.1552 84.6444 36.7356
(B6.5XFAD x BXD65)F1-Ntg f 60.3275 6.0776 72.3047 48.3503
(B6.5XFAD x BXD65)F1-Ntg m 63.765 12.1552 87.7194 39.8106
(B6.5XFAD x BXD66)F1-ADtg f 32.78 9.9247 52.3387 13.2213
(B6.5XFAD x BXD66)F1-ADtg m 15.52 7.6877 30.6701 0.3699
(B6.5XFAD x BXD68)F1-ADtg f 29.4633 9.9247 49.022 9.9046
(B6.5XFAD x BXD68)F1-ADtg m 44.5429 6.4973 57.347 31.7387
(B6.5XFAD x BXD68)F1-Ntg f 55.151 5.436 65.8637 44.4383
(B6.5XFAD x BXD68)F1-Ntg m 54.1 12.1552 78.0544 30.1456
(B6.5XFAD x BXD69)F1-ADtg f 11.5683 7.0178 25.3984 -2.2618
(B6.5XFAD x BXD69)F1-ADtg m 23.814 7.6877 38.9641 8.6639
(B6.5XFAD x BXD69)F1-Ntg f 33.0175 8.5951 49.9558 16.0792
(B6.5XFAD x BXD69)F1-Ntg m 20.18 7.0178 34.0101 6.3499
(B6.5XFAD x BXD70)F1-Ntg f 57.6667 9.9247 77.2254 38.108
(B6.5XFAD x BXD70)F1-Ntg m 32.515 12.1552 56.4694 8.5606
(B6.5XFAD x BXD75)F1-ADtg f 5.6225 8.5951 22.5608 -11.3158
(B6.5XFAD x BXD75)F1-ADtg m 13.3175 8.5951 30.2558 -3.6208
(B6.5XFAD x BXD77)F1-ADtg f 9.65 9.9247 29.2087 -9.9087
(B6.5XFAD x BXD77)F1-ADtg m 22.6733 9.9247 42.232 3.1146
(B6.5XFAD x BXD77)F1-Ntg f 24.689 5.436 35.4017 13.9763
(B6.5XFAD x BXD77)F1-Ntg m 21.8183 7.0178 35.6484 7.9882
(B6.5XFAD x BXD87)F1-ADtg f 22.135 5.436 32.8477 11.4223
(B6.5XFAD x BXD87)F1-ADtg m 30.525 8.5951 47.4633 13.5867
(B6.5XFAD x BXD89)F1-Ntg f 35.605 12.1552 59.5594 11.6506
(B6.5XFAD x BXD89)F1-Ntg m 35.825 12.1552 59.7794 11.8706
(B6.5XFAD x D2)F1-ADtg f 8.6306 4.1692 16.8469 0.4143
(B6.5XFAD x D2)F1-ADtg m 7.42 6.0776 19.3972 -4.5572
(B6.5XFAD x D2)F1-Ntg f 12.0442 4.9624 21.8235 2.2648
(B6.5XFAD x D2)F1-Ntg m 17.525 8.5951 34.4633 0.5867


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 51.2674 3.8632 58.8806 43.6542
(B6.5XFAD x BXD100)F1-ADtg both 14.0257 6.8914 27.6066 0.4448
(B6.5XFAD x BXD100)F1-Ntg both 26.9271 5.5481 37.8607 15.9934
(B6.5XFAD x BXD32)F1-ADtg both 20.8275 7.8462 36.29 5.365
(B6.5XFAD x BXD32)F1-Ntg both 33.5417 7.8462 49.0042 18.0791
(B6.5XFAD x BXD44)F1-ADtg both 18.8786 3.8623 26.4899 11.2672
(B6.5XFAD x BXD60)F1-ADtg both 22.2012 5.7657 33.5638 10.8387
(B6.5XFAD x BXD61)F1-ADtg both 22.9524 5.9312 34.6409 11.2638
(B6.5XFAD x BXD61)F1-Ntg both 35.2337 5.2046 45.4903 24.977
(B6.5XFAD x BXD62)F1-ADtg both 15.395 7.8462 30.8575 -0.0675
(B6.5XFAD x BXD62)F1-Ntg both 65.62 7.0178 79.4501 51.7899
(B6.5XFAD x BXD65)F1-ADtg both 50.5342 7.0178 64.3643 36.7041
(B6.5XFAD x BXD65)F1-Ntg both 62.0462 6.795 75.4372 48.6553
(B6.5XFAD x BXD66)F1-ADtg both 24.15 6.2769 36.52 11.78
(B6.5XFAD x BXD68)F1-ADtg both 37.0031 5.9312 48.6917 25.3145
(B6.5XFAD x BXD68)F1-Ntg both 54.6255 6.6577 67.7459 41.5051
(B6.5XFAD x BXD69)F1-ADtg both 17.6912 5.2046 27.9478 7.4345
(B6.5XFAD x BXD69)F1-Ntg both 26.5987 5.5481 37.5324 15.6651
(B6.5XFAD x BXD70)F1-Ntg both 45.0908 7.8462 60.5534 29.6283
(B6.5XFAD x BXD75)F1-ADtg both 9.47 6.0776 21.4472 -2.5072
(B6.5XFAD x BXD77)F1-ADtg both 16.1617 7.0178 29.9918 2.3316
(B6.5XFAD x BXD77)F1-Ntg both 23.2537 4.4385 32.0006 14.5067
(B6.5XFAD x BXD87)F1-ADtg both 26.33 5.0849 36.3509 16.3091
(B6.5XFAD x BXD89)F1-Ntg both 35.715 8.5951 52.6533 18.7767
(B6.5XFAD x D2)F1-ADtg both 8.0253 3.6851 15.2875 0.763
(B6.5XFAD x D2)F1-Ntg both 14.7846 4.9624 24.5639 5.0052




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA