Phenotype measure:   Neuner1   cfm_14mo_bin4

ID, description, units MPD:65983   cfm_14mo_bin4   percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test   [%]  4th 2 min
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test 4th 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means28.96   % 33.175   %
Median of the strain means25.112   % 28.442   %
SD of the strain means± 17.911 ± 18.052
Coefficient of variation (CV)0.6185 0.5441
Min–max range of strain means0.445   –   83.52   % 0.89   –   87.32   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1279.948 1279.948 3.8909 0.0498
strain 25 65187.661 2607.5064 7.9264 < 0.0001
sex:strain 25 12304.1678 492.1667 1.4961 0.0669
Residuals 222 73029.8781 328.9634


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 49.97 22.548   27 4.3393 0.4512 2.67, 82.18 0.93
(B6.5XFAD x B6)F1-Ntg f 49.629 18.121   9 6.0404 0.3651 25.78, 82.18 1.15
(B6.5XFAD x B6)F1-Ntg m 53.54 15.308   11 4.6154 0.2859 34.74, 81.07 1.13
(B6.5XFAD x BXD100)F1-ADtg f 19.89 18.696   2   13.22 0.94 6.67, 33.11 -0.51
(B6.5XFAD x BXD100)F1-ADtg m 22.764 15.147   7 5.7252 0.6654 1.56, 44.99 -0.58
(B6.5XFAD x BXD100)F1-Ntg f 37.078 2.1719   4 1.0859 0.0586 34.0, 39.11 0.45
(B6.5XFAD x BXD100)F1-Ntg m 26.015 10.651   6 4.3483 0.4094 14.03, 39.11 -0.4
(B6.5XFAD x BXD14)F1-ADtg f 2.0 2.8284   2   2.0 1.4142 -1.51
(B6.5XFAD x BXD14)F1-Ntg f 27.67 0.15556   2   0.11 0.0056 27.56, 27.78 -0.07
(B6.5XFAD x BXD16)F1-ADtg f 55.85 29.738   4 14.869 0.5325 22.67, 87.08 1.5
(B6.5XFAD x BXD22)F1-ADtg f 19.56 22.627   2   16.0 1.1568 3.56, 35.56 -0.52
(B6.5XFAD x BXD22)F1-Ntg f 34.075 34.33   2   24.275 1.0075 9.8, 58.35 0.29
(B6.5XFAD x BXD32)F1-ADtg f 0.445 0.62933   2   0.445 1.4142 -1.59
(B6.5XFAD x BXD32)F1-ADtg m 49.777 23.606   3 13.629 0.4742 26.06, 73.27 0.92
(B6.5XFAD x BXD32)F1-Ntg f 15.787 16.93   3 9.7745 1.0724 3.56, 35.11 -0.74
(B6.5XFAD x BXD32)F1-Ntg m 72.5 27.556   2   19.485 0.3801 53.01, 91.98 2.18
(B6.5XFAD x BXD42)F1-ADtg f 32.96 16.377   2   11.58 0.4969 21.38, 44.54 0.22
(B6.5XFAD x BXD42)F1-Ntg f 13.59 0.0   1   0.0 0.0 13.59, 13.59 -0.86
(B6.5XFAD x BXD44)F1-ADtg f 25.777 21.695   13 6.017 0.8416 -0.18
(B6.5XFAD x BXD44)F1-ADtg m 23.047 18.57   8 6.5654 0.8057 -0.56
(B6.5XFAD x BXD44)F1-Ntg f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.39
(B6.5XFAD x BXD44)F1-Ntg m 30.393 4.0576   3 2.3427 0.1335 26.0, 34.0 -0.15
(B6.5XFAD x BXD51)F1-ADtg f 34.163 18.512   6 7.5576 0.5419 11.58, 64.0 0.29
(B6.5XFAD x BXD51)F1-Ntg f 37.865 22.942   4 11.471 0.6059 4.67, 56.57 0.5
(B6.5XFAD x BXD55)F1-ADtg f 16.223 20.681   4 10.34 1.2748 3.78, 47.11 -0.71
(B6.5XFAD x BXD55)F1-Ntg f 11.35 4.4265   2   3.13 0.39 8.22, 14.48 -0.98
(B6.5XFAD x BXD56)F1-ADtg m 25.33 0.0   1   0.0 0.0 25.33, 25.33 -0.43
(B6.5XFAD x BXD56)F1-Ntg f 37.415 51.34   2   36.305 1.3723 1.11, 73.72 0.47
(B6.5XFAD x BXD56)F1-Ntg m 0.89 0.0   1   0.0 0.0 0.89, 0.89 -1.79
(B6.5XFAD x BXD60)F1-ADtg f 14.127 3.8202   4 1.9101 0.2704 8.69, 17.56 -0.83
(B6.5XFAD x BXD60)F1-ADtg m 18.41 9.777   5 4.3724 0.5311 7.8, 32.22 -0.82
(B6.5XFAD x BXD60)F1-Ntg f 21.727 8.3721   3 4.8336 0.3853 13.56, 30.29 -0.4
(B6.5XFAD x BXD61)F1-ADtg f 14.399 11.263   7 4.2571 0.7822 -0.81
(B6.5XFAD x BXD61)F1-ADtg m 32.627 11.531   3 6.6576 0.3534 24.89, 45.88 -0.03
(B6.5XFAD x BXD61)F1-Ntg f 35.912 19.438   5 8.6931 0.5413 5.35, 59.24 0.39
(B6.5XFAD x BXD61)F1-Ntg m 39.825 17.962   6 7.3328 0.451 22.67, 70.38 0.37
(B6.5XFAD x BXD62)F1-ADtg f 28.097 3.6874   3 2.1289 0.1312 24.22, 31.56 -0.05
(B6.5XFAD x BXD62)F1-ADtg m 35.445 29.38   2   20.775 0.8289 14.67, 56.22 0.13
(B6.5XFAD x BXD62)F1-Ntg f 71.96 12.169   3 7.0256 0.1691 57.91, 79.29 2.4
(B6.5XFAD x BXD62)F1-Ntg m 70.75 9.8135   3 5.6658 0.1387 61.25, 80.85 2.08
(B6.5XFAD x BXD65)F1-ADtg f 41.065 33.562   6 13.702 0.8173 2.45, 83.56 0.68
(B6.5XFAD x BXD65)F1-ADtg m 40.575 31.558   2   22.315 0.7778 18.26, 62.89 0.41
(B6.5XFAD x BXD65)F1-Ntg f 63.94 18.963   8 6.7043 0.2966 27.33, 83.11 1.95
(B6.5XFAD x BXD65)F1-Ntg m 87.32 2.1779   2   1.54 0.0249 85.78, 88.86 3.0
(B6.5XFAD x BXD66)F1-ADtg f 40.013 9.4756   3 5.4707 0.2368 30.29, 49.22 0.62
(B6.5XFAD x BXD66)F1-ADtg m 26.7 12.581   5 5.6266 0.4712 15.33, 42.0 -0.36
(B6.5XFAD x BXD66)F1-Ntg f 16.22 0.0   1   0.0 0.0 16.22, 16.22 -0.71
(B6.5XFAD x BXD66)F1-Ntg m 29.547 14.264   3 8.2355 0.4828 14.03, 42.09 -0.2
(B6.5XFAD x BXD68)F1-ADtg f 28.443 14.221   3 8.2102 0.5 13.33, 41.56 -0.03
(B6.5XFAD x BXD68)F1-ADtg m 39.417 16.643   7 6.2904 0.4222 15.59, 63.7 0.35
(B6.5XFAD x BXD68)F1-Ntg f 51.51 29.537   10 9.3403 0.5735 4.44, 89.98 1.26
(B6.5XFAD x BXD68)F1-Ntg m 49.475 32.803   2   23.195 0.663 26.28, 72.67 0.9
(B6.5XFAD x BXD69)F1-ADtg f 24.447 20.997   6 8.572 0.8589 1.34, 46.89 -0.25
(B6.5XFAD x BXD69)F1-ADtg m 27.854 15.044   5 6.728 0.5401 10.24, 46.99 -0.29
(B6.5XFAD x BXD69)F1-Ntg f 27.807 9.4774   4 4.7387 0.3408 19.33, 37.56 -0.06
(B6.5XFAD x BXD69)F1-Ntg m 39.63 27.287   6 11.14 0.6885 5.33, 81.29 0.36
(B6.5XFAD x BXD70)F1-ADtg f 22.94 0.0   1   0.0 0.0 22.94, 22.94 -0.34
(B6.5XFAD x BXD70)F1-ADtg m 12.443 11.338   3 6.546 0.9112 4.0, 25.33 -1.15
(B6.5XFAD x BXD70)F1-Ntg f 52.34 12.746   3 7.3592 0.2435 37.78, 61.47 1.31
(B6.5XFAD x BXD70)F1-Ntg m 24.385 9.6096   2   6.795 0.3941 17.59, 31.18 -0.49
(B6.5XFAD x BXD75)F1-ADtg f 6.2925 9.6004   4 4.8002 1.5257 -1.27
(B6.5XFAD x BXD75)F1-ADtg m 21.087 8.3661   4 4.1831 0.3967 9.56, 28.73 -0.67
(B6.5XFAD x BXD75)F1-Ntg f 21.788 18.93   6 7.7283 0.8688 2.67, 53.01 -0.4
(B6.5XFAD x BXD75)F1-Ntg m 19.15 0.0   1   0.0 0.0 19.15, 19.15 -0.78
(B6.5XFAD x BXD77)F1-ADtg f 3.7867 6.5587   3 3.7867 1.7321 -1.41
(B6.5XFAD x BXD77)F1-ADtg m 26.753 12.765   3 7.3697 0.4771 15.59, 40.67 -0.36
(B6.5XFAD x BXD77)F1-Ntg f 22.571 15.619   10 4.9392 0.692 1.78, 48.89 -0.36
(B6.5XFAD x BXD77)F1-Ntg m 18.125 14.676   6 5.9913 0.8097 9.8, 47.78 -0.83
(B6.5XFAD x BXD81)F1-ADtg f 14.603 10.911   6 4.4546 0.7472 -0.8
(B6.5XFAD x BXD81)F1-Ntg f 30.29 7.6948   5 3.4412 0.254 23.78, 43.33 0.07
(B6.5XFAD x BXD87)F1-ADtg f 18.293 17.281   10 5.4647 0.9447 -0.6
(B6.5XFAD x BXD87)F1-ADtg m 32.67 24.294   4 12.147 0.7436 12.25, 67.93 -0.03
(B6.5XFAD x BXD87)F1-Ntg f 21.153 30.482   3 17.599 1.441 3.33, 56.35 -0.44
(B6.5XFAD x BXD87)F1-Ntg m 36.08 0.0   1   0.0 0.0 36.08, 36.08 0.16
(B6.5XFAD x BXD89)F1-ADtg m 14.22 0.0   1   0.0 0.0 14.22, 14.22 -1.05
(B6.5XFAD x BXD89)F1-Ntg f 56.52 15.5   2   10.96 0.2742 45.56, 67.48 1.54
(B6.5XFAD x BXD89)F1-Ntg m 25.78 9.7439   2   6.89 0.378 18.89, 32.67 -0.41
(B6.5XFAD x BXD99)F1-ADtg f 83.52 0.0   1   0.0 0.0 83.52, 83.52 3.05
(B6.5XFAD x BXD99)F1-Ntg f 31.63 0.0   1   0.0 0.0 31.63, 31.63 0.15
(B6.5XFAD x D2)F1-ADtg f 7.93 13.327   17 3.2323 1.6806 -1.17
(B6.5XFAD x D2)F1-ADtg m 10.195 13.95   8 4.9322 1.3684 -1.27
(B6.5XFAD x D2)F1-Ntg f 23.438 23.109   12 6.671 0.986 3.11, 64.89 -0.31
(B6.5XFAD x D2)F1-Ntg m 28.442 24.271   4 12.135 0.8533 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 49.6289 6.0458 61.5434 37.7144
(B6.5XFAD x B6)F1-Ntg m 53.5436 5.4686 64.3207 42.7666
(B6.5XFAD x BXD100)F1-ADtg f 19.89 12.825 45.1644 -5.3844
(B6.5XFAD x BXD100)F1-ADtg m 22.7643 6.8553 36.274 9.2545
(B6.5XFAD x BXD100)F1-Ntg f 37.0775 9.0687 54.9492 19.2058
(B6.5XFAD x BXD100)F1-Ntg m 26.015 7.4045 40.6072 11.4228
(B6.5XFAD x BXD32)F1-ADtg f 0.445 12.825 25.7194 -24.8294
(B6.5XFAD x BXD32)F1-ADtg m 49.7767 10.4716 70.4131 29.1402
(B6.5XFAD x BXD32)F1-Ntg f 15.7867 10.4716 36.4231 -4.8498
(B6.5XFAD x BXD32)F1-Ntg m 72.495 12.825 97.7694 47.2206
(B6.5XFAD x BXD44)F1-ADtg f 25.7769 5.0304 35.6904 15.8635
(B6.5XFAD x BXD44)F1-ADtg m 23.0475 6.4125 35.6847 10.4103
(B6.5XFAD x BXD60)F1-ADtg f 14.1275 9.0687 31.9992 -3.7442
(B6.5XFAD x BXD60)F1-ADtg m 18.41 8.1113 34.3949 2.4251
(B6.5XFAD x BXD61)F1-ADtg f 14.3986 6.8553 27.9083 0.8888
(B6.5XFAD x BXD61)F1-ADtg m 32.6267 10.4716 53.2631 11.9902
(B6.5XFAD x BXD61)F1-Ntg f 35.912 8.1113 51.8969 19.9271
(B6.5XFAD x BXD61)F1-Ntg m 39.825 7.4045 54.4172 25.2328
(B6.5XFAD x BXD62)F1-ADtg f 28.0967 10.4716 48.7331 7.4602
(B6.5XFAD x BXD62)F1-ADtg m 35.445 12.825 60.7194 10.1706
(B6.5XFAD x BXD62)F1-Ntg f 71.9567 10.4716 92.5931 51.3202
(B6.5XFAD x BXD62)F1-Ntg m 70.7533 10.4716 91.3898 50.1169
(B6.5XFAD x BXD65)F1-ADtg f 41.065 7.4045 55.6572 26.4728
(B6.5XFAD x BXD65)F1-ADtg m 40.575 12.825 65.8494 15.3006
(B6.5XFAD x BXD65)F1-Ntg f 63.9425 6.4125 76.5797 51.3053
(B6.5XFAD x BXD65)F1-Ntg m 87.32 12.825 112.5944 62.0456
(B6.5XFAD x BXD66)F1-ADtg f 40.0133 10.4716 60.6498 19.3769
(B6.5XFAD x BXD66)F1-ADtg m 26.7 8.1113 42.6849 10.7151
(B6.5XFAD x BXD68)F1-ADtg f 28.4433 10.4716 49.0798 7.8069
(B6.5XFAD x BXD68)F1-ADtg m 39.4171 6.8553 52.9269 25.9074
(B6.5XFAD x BXD68)F1-Ntg f 51.505 5.7355 62.8081 40.2019
(B6.5XFAD x BXD68)F1-Ntg m 49.475 12.825 74.7494 24.2006
(B6.5XFAD x BXD69)F1-ADtg f 24.4467 7.4045 39.0389 9.8545
(B6.5XFAD x BXD69)F1-ADtg m 27.854 8.1113 43.8389 11.8691
(B6.5XFAD x BXD69)F1-Ntg f 27.8075 9.0687 45.6792 9.9358
(B6.5XFAD x BXD69)F1-Ntg m 39.63 7.4045 54.2222 25.0378
(B6.5XFAD x BXD70)F1-Ntg f 52.3433 10.4716 72.9798 31.7069
(B6.5XFAD x BXD70)F1-Ntg m 24.385 12.825 49.6594 -0.8894
(B6.5XFAD x BXD75)F1-ADtg f 6.2925 9.0687 24.1642 -11.5792
(B6.5XFAD x BXD75)F1-ADtg m 21.0875 9.0687 38.9592 3.2158
(B6.5XFAD x BXD77)F1-ADtg f 3.7867 10.4716 24.4231 -16.8498
(B6.5XFAD x BXD77)F1-ADtg m 26.7533 10.4716 47.3898 6.1169
(B6.5XFAD x BXD77)F1-Ntg f 22.571 5.7355 33.8741 11.2679
(B6.5XFAD x BXD77)F1-Ntg m 18.125 7.4045 32.7172 3.5328
(B6.5XFAD x BXD87)F1-ADtg f 18.293 5.7355 29.5961 6.9899
(B6.5XFAD x BXD87)F1-ADtg m 32.67 9.0687 50.5417 14.7983
(B6.5XFAD x BXD89)F1-Ntg f 56.52 12.825 81.7944 31.2456
(B6.5XFAD x BXD89)F1-Ntg m 25.78 12.825 51.0544 0.5056
(B6.5XFAD x D2)F1-ADtg f 7.93 4.399 16.599 -0.739
(B6.5XFAD x D2)F1-ADtg m 10.195 6.4125 22.8322 -2.4422
(B6.5XFAD x D2)F1-Ntg f 23.4383 5.2358 33.7566 13.1201
(B6.5XFAD x D2)F1-Ntg m 28.4425 9.0687 46.3142 10.5708


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 51.5863 4.0761 59.619 43.5535
(B6.5XFAD x BXD100)F1-ADtg both 21.3271 7.2711 35.6564 6.9979
(B6.5XFAD x BXD100)F1-Ntg both 31.5463 5.8538 43.0824 20.0101
(B6.5XFAD x BXD32)F1-ADtg both 25.1108 8.2785 41.4254 8.7963
(B6.5XFAD x BXD32)F1-Ntg both 44.1408 8.2785 60.4554 27.8263
(B6.5XFAD x BXD44)F1-ADtg both 24.4122 4.0751 32.443 16.3814
(B6.5XFAD x BXD60)F1-ADtg both 16.2687 6.0835 28.2575 4.28
(B6.5XFAD x BXD61)F1-ADtg both 23.5126 6.258 35.8453 11.18
(B6.5XFAD x BXD61)F1-Ntg both 37.8685 5.4914 48.6904 27.0466
(B6.5XFAD x BXD62)F1-ADtg both 31.7708 8.2785 48.0854 15.4563
(B6.5XFAD x BXD62)F1-Ntg both 71.355 7.4045 85.9472 56.7628
(B6.5XFAD x BXD65)F1-ADtg both 40.82 7.4045 55.4122 26.2278
(B6.5XFAD x BXD65)F1-Ntg both 75.6313 7.1694 89.7601 61.5024
(B6.5XFAD x BXD66)F1-ADtg both 33.3567 6.6228 46.4083 20.305
(B6.5XFAD x BXD68)F1-ADtg both 33.9302 6.258 46.2629 21.5976
(B6.5XFAD x BXD68)F1-Ntg both 50.49 7.0246 64.3334 36.6466
(B6.5XFAD x BXD69)F1-ADtg both 26.1503 5.4914 36.9722 15.3285
(B6.5XFAD x BXD69)F1-Ntg both 33.7188 5.8538 45.2549 22.1826
(B6.5XFAD x BXD70)F1-Ntg both 38.3642 8.2785 54.6787 22.0496
(B6.5XFAD x BXD75)F1-ADtg both 13.69 6.4125 26.3272 1.0528
(B6.5XFAD x BXD77)F1-ADtg both 15.27 7.4045 29.8622 0.6778
(B6.5XFAD x BXD77)F1-Ntg both 20.348 4.683 29.5769 11.1191
(B6.5XFAD x BXD87)F1-ADtg both 25.4815 5.3651 36.0545 14.9085
(B6.5XFAD x BXD89)F1-Ntg both 41.15 9.0687 59.0217 23.2783
(B6.5XFAD x D2)F1-ADtg both 9.0625 3.8882 16.7249 1.4001
(B6.5XFAD x D2)F1-Ntg both 25.9404 5.2358 36.2586 15.6222




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA