Phenotype measure:   Neuner1   cfm_14mo_bin3

ID, description, units MPD:65982   cfm_14mo_bin3   percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test   [%]  3rd 2 min
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test 3rd 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means33.347   % 38.722   %
Median of the strain means29.203   % 35.745   %
SD of the strain means± 19.085 ± 19.363
Coefficient of variation (CV)0.5723 0.5
Min–max range of strain means0.0   –   88.86   % 0.0   –   88.2   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1848.9039 1848.9039 5.1228 0.0246
strain 25 69589.6701 2783.5868 7.7126 < 0.0001
sex:strain 25 11098.632 443.9453 1.2301 0.2147
Residuals 222 80123.3646 360.9161


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 50.74 23.725   27 4.5659 0.4676 17.15, 96.0 0.62
(B6.5XFAD x B6)F1-Ntg f 57.57 15.76   9 5.2535 0.2737 37.42, 79.11 1.27
(B6.5XFAD x B6)F1-Ntg m 59.18 21.899   11 6.6027 0.37 18.22, 97.78 1.06
(B6.5XFAD x BXD100)F1-ADtg f 12.92 4.7235   2   3.34 0.3656 9.58, 16.26 -1.07
(B6.5XFAD x BXD100)F1-ADtg m 22.371 19.121   7 7.2269 0.8547 3.12, 45.21 -0.84
(B6.5XFAD x BXD100)F1-Ntg f 31.825 11.041   4 5.5206 0.3469 17.59, 43.65 -0.08
(B6.5XFAD x BXD100)F1-Ntg m 36.523 21.298   6 8.6949 0.5831 8.0, 59.47 -0.11
(B6.5XFAD x BXD14)F1-ADtg f 0.89 1.2587   2   0.89 1.4142 -1.7
(B6.5XFAD x BXD14)F1-Ntg f 39.31 16.221   2   11.47 0.4126 27.84, 50.78 0.31
(B6.5XFAD x BXD16)F1-ADtg f 46.712 15.963   4 7.9813 0.3417 34.44, 69.56 0.7
(B6.5XFAD x BXD22)F1-ADtg f 40.645 55.27   2   39.085 1.3599 1.56, 79.73 0.38
(B6.5XFAD x BXD22)F1-Ntg f 42.0 19.488   2   13.78 0.464 28.22, 55.78 0.45
(B6.5XFAD x BXD32)F1-ADtg f 0.67 0.94752   2   0.67 1.4142 -1.71
(B6.5XFAD x BXD32)F1-ADtg m 62.15 14.826   3 8.5597 0.2385 46.1, 75.33 1.21
(B6.5XFAD x BXD32)F1-Ntg f 14.85 11.919   3 6.8816 0.8026 3.12, 26.95 -0.97
(B6.5XFAD x BXD32)F1-Ntg m 53.73 12.509   2   8.845 0.2328 44.89, 62.58 0.78
(B6.5XFAD x BXD42)F1-ADtg f 28.51 7.2408   2   5.12 0.254 23.39, 33.63 -0.25
(B6.5XFAD x BXD42)F1-Ntg f 19.82 0.0   1   0.0 0.0 19.82, 19.82 -0.71
(B6.5XFAD x BXD44)F1-ADtg f 25.868 28.171   13 7.8133 1.0891 -0.39
(B6.5XFAD x BXD44)F1-ADtg m 28.876 24.619   8 8.704 0.8526 1.6, 78.62 -0.51
(B6.5XFAD x BXD44)F1-Ntg f 59.24 0.0   1   0.0 0.0 59.24, 59.24 1.36
(B6.5XFAD x BXD44)F1-Ntg m 34.12 7.0812   3 4.0883 0.2075 28.29, 42.0 -0.24
(B6.5XFAD x BXD51)F1-ADtg f 29.157 15.359   6 6.2704 0.5268 10.89, 48.78 -0.22
(B6.5XFAD x BXD51)F1-Ntg f 56.19 28.628   4 14.314 0.5095 20.71, 87.11 1.2
(B6.5XFAD x BXD55)F1-ADtg f 20.992 26.236   4 13.118 1.2498 0.45, 58.8 -0.65
(B6.5XFAD x BXD55)F1-Ntg f 18.455 10.981   2   7.765 0.595 10.69, 26.22 -0.78
(B6.5XFAD x BXD56)F1-ADtg m 79.96 0.0   1   0.0 0.0 79.96, 79.96 2.13
(B6.5XFAD x BXD56)F1-Ntg f 43.89 59.24   2   41.89 1.3498 2.0, 85.78 0.55
(B6.5XFAD x BXD56)F1-Ntg m 10.22 0.0   1   0.0 0.0 10.22, 10.22 -1.47
(B6.5XFAD x BXD60)F1-ADtg f 22.258 7.8124   4 3.9062 0.351 13.56, 29.4 -0.58
(B6.5XFAD x BXD60)F1-ADtg m 23.334 14.392   5 6.4362 0.6168 8.44, 42.98 -0.79
(B6.5XFAD x BXD60)F1-Ntg f 34.643 7.8513   3 4.5329 0.2266 27.39, 42.98 0.07
(B6.5XFAD x BXD61)F1-ADtg f 21.87 13.287   7 5.0222 0.6076 -0.6
(B6.5XFAD x BXD61)F1-ADtg m 28.703 17.565   3 10.141 0.6119 8.69, 41.56 -0.52
(B6.5XFAD x BXD61)F1-Ntg f 46.266 24.948   5 11.157 0.5392 9.58, 70.89 0.68
(B6.5XFAD x BXD61)F1-Ntg m 42.33 21.058   6 8.5967 0.4975 17.11, 75.33 0.19
(B6.5XFAD x BXD62)F1-ADtg f 23.74 21.3   3 12.297 0.8972 3.12, 45.66 -0.5
(B6.5XFAD x BXD62)F1-ADtg m 35.745 29.451   2   20.825 0.8239 14.92, 56.57 -0.15
(B6.5XFAD x BXD62)F1-Ntg f 76.41 7.5518   3 4.3601 0.0988 67.93, 82.41 2.26
(B6.5XFAD x BXD62)F1-Ntg m 72.97 6.4758   3 3.7388 0.0888 65.56, 77.56 1.77
(B6.5XFAD x BXD65)F1-ADtg f 41.513 28.93   6 11.811 0.6969 11.11, 87.75 0.43
(B6.5XFAD x BXD65)F1-ADtg m 52.56 40.63   2   28.73 0.773 23.83, 81.29 0.71
(B6.5XFAD x BXD65)F1-Ntg f 53.52 20.984   8 7.4191 0.3921 30.51, 92.22 1.06
(B6.5XFAD x BXD65)F1-Ntg m 88.2 1.2587   2   0.89 0.0143 87.31, 89.09 2.56
(B6.5XFAD x BXD66)F1-ADtg f 31.037 10.208   3 5.8935 0.3289 22.22, 42.22 -0.12
(B6.5XFAD x BXD66)F1-ADtg m 27.584 11.397   5 5.0968 0.4132 18.22, 45.66 -0.58
(B6.5XFAD x BXD66)F1-Ntg f 16.48 0.0   1   0.0 0.0 16.48, 16.48 -0.88
(B6.5XFAD x BXD66)F1-Ntg m 34.813 23.665   3 13.663 0.6798 11.11, 58.44 -0.2
(B6.5XFAD x BXD68)F1-ADtg f 47.29 14.269   3 8.2381 0.3017 34.74, 62.81 0.73
(B6.5XFAD x BXD68)F1-ADtg m 44.103 4.5145   7 1.7063 0.1024 34.74, 48.22 0.28
(B6.5XFAD x BXD68)F1-Ntg f 53.43 30.715   10 9.7128 0.5749 3.56, 98.22 1.05
(B6.5XFAD x BXD68)F1-Ntg m 54.42 39.577   2   27.985 0.7272 26.44, 82.41 0.81
(B6.5XFAD x BXD69)F1-ADtg f 27.17 20.659   6 8.4341 0.7604 2.22, 50.56 -0.32
(B6.5XFAD x BXD69)F1-ADtg m 37.792 23.562   5 10.537 0.6235 11.78, 62.58 -0.05
(B6.5XFAD x BXD69)F1-Ntg f 29.25 17.902   4 8.9509 0.612 12.44, 51.78 -0.21
(B6.5XFAD x BXD69)F1-Ntg m 40.347 25.368   6 10.356 0.6287 15.59, 73.56 0.08
(B6.5XFAD x BXD70)F1-ADtg f 42.98 0.0   1   0.0 0.0 42.98, 42.98 0.5
(B6.5XFAD x BXD70)F1-ADtg m 37.117 16.437   3 9.4897 0.4428 21.6, 54.34 -0.08
(B6.5XFAD x BXD70)F1-Ntg f 54.44 19.111   3 11.034 0.351 32.96, 69.56 1.11
(B6.5XFAD x BXD70)F1-Ntg m 30.335 23.101   2   16.335 0.7615 14.0, 46.67 -0.43
(B6.5XFAD x BXD75)F1-ADtg f 2.2225 3.3646   4 1.6823 1.5139 -1.63
(B6.5XFAD x BXD75)F1-ADtg m 11.12 4.4583   4 2.2292 0.4009 7.35, 17.56 -1.43
(B6.5XFAD x BXD75)F1-Ntg f 35.45 18.986   6 7.751 0.5356 11.56, 58.44 0.11
(B6.5XFAD x BXD75)F1-Ntg m 38.44 0.0   1   0.0 0.0 38.44, 38.44 -0.01
(B6.5XFAD x BXD77)F1-ADtg f 0.0 0.0   3 0.0 None -1.75
(B6.5XFAD x BXD77)F1-ADtg m 29.77 10.982   3 6.3405 0.3689 17.82, 39.42 -0.46
(B6.5XFAD x BXD77)F1-Ntg f 28.233 17.647   10 5.5805 0.625 1.56, 60.44 -0.27
(B6.5XFAD x BXD77)F1-Ntg m 26.282 13.497   6 5.5099 0.5135 7.8, 42.32 -0.64
(B6.5XFAD x BXD81)F1-ADtg f 21.148 17.042   6 6.9572 0.8058 -0.64
(B6.5XFAD x BXD81)F1-Ntg f 40.104 24.924   5 11.146 0.6215 10.24, 75.95 0.35
(B6.5XFAD x BXD87)F1-ADtg f 28.518 12.905   10 4.0809 0.4525 10.0, 46.89 -0.25
(B6.5XFAD x BXD87)F1-ADtg m 34.855 25.408   4 12.704 0.729 10.0, 69.33 -0.2
(B6.5XFAD x BXD87)F1-Ntg f 24.453 31.75   3 18.331 1.2984 5.57, 61.11 -0.47
(B6.5XFAD x BXD87)F1-Ntg m 56.67 0.0   1   0.0 0.0 56.67, 56.67 0.93
(B6.5XFAD x BXD89)F1-ADtg m 0.0 0.0   1   0.0 None -2.0
(B6.5XFAD x BXD89)F1-Ntg f 60.48 31.049   2   21.955 0.5133 38.53, 82.44 1.42
(B6.5XFAD x BXD89)F1-Ntg m 31.295 1.7324   2   1.225 0.0554 30.07, 32.52 -0.38
(B6.5XFAD x BXD99)F1-ADtg f 88.86 0.0   1   0.0 0.0 88.86, 88.86 2.91
(B6.5XFAD x BXD99)F1-Ntg f 23.39 0.0   1   0.0 0.0 23.39, 23.39 -0.52
(B6.5XFAD x D2)F1-ADtg f 7.3047 10.612   17 2.5738 1.4528 -1.36
(B6.5XFAD x D2)F1-ADtg m 9.2688 9.541   8 3.3732 1.0294 -1.52
(B6.5XFAD x D2)F1-Ntg f 28.683 15.096   12 4.3578 0.5263 7.35, 58.44 -0.24
(B6.5XFAD x D2)F1-Ntg m 29.343 18.693   4 9.3467 0.6371 4.68, 50.11 -0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 57.5722 6.3326 70.0519 45.0925
(B6.5XFAD x B6)F1-Ntg m 59.1782 5.728 70.4665 47.8899
(B6.5XFAD x BXD100)F1-ADtg f 12.92 13.4335 39.3934 -13.5534
(B6.5XFAD x BXD100)F1-ADtg m 22.3714 7.1805 36.5221 8.2208
(B6.5XFAD x BXD100)F1-Ntg f 31.825 9.4989 50.5445 13.1055
(B6.5XFAD x BXD100)F1-Ntg m 36.5233 7.7558 51.8078 21.2389
(B6.5XFAD x BXD32)F1-ADtg f 0.67 13.4335 27.1434 -25.8034
(B6.5XFAD x BXD32)F1-ADtg m 62.1533 10.9684 83.7688 40.5379
(B6.5XFAD x BXD32)F1-Ntg f 14.85 10.9684 36.4655 -6.7655
(B6.5XFAD x BXD32)F1-Ntg m 53.735 13.4335 80.2084 27.2616
(B6.5XFAD x BXD44)F1-ADtg f 25.8677 5.269 36.2514 15.484
(B6.5XFAD x BXD44)F1-ADtg m 28.8763 6.7167 42.113 15.6395
(B6.5XFAD x BXD60)F1-ADtg f 22.2575 9.4989 40.977 3.538
(B6.5XFAD x BXD60)F1-ADtg m 23.334 8.4961 40.0773 6.5907
(B6.5XFAD x BXD61)F1-ADtg f 21.87 7.1805 36.0206 7.7194
(B6.5XFAD x BXD61)F1-ADtg m 28.7033 10.9684 50.3188 7.0879
(B6.5XFAD x BXD61)F1-Ntg f 46.266 8.4961 63.0093 29.5227
(B6.5XFAD x BXD61)F1-Ntg m 42.33 7.7558 57.6144 27.0456
(B6.5XFAD x BXD62)F1-ADtg f 23.74 10.9684 45.3555 2.1245
(B6.5XFAD x BXD62)F1-ADtg m 35.745 13.4335 62.2184 9.2716
(B6.5XFAD x BXD62)F1-Ntg f 76.41 10.9684 98.0255 54.7945
(B6.5XFAD x BXD62)F1-Ntg m 72.9667 10.9684 94.5821 51.3512
(B6.5XFAD x BXD65)F1-ADtg f 41.5133 7.7558 56.7978 26.2289
(B6.5XFAD x BXD65)F1-ADtg m 52.56 13.4335 79.0334 26.0866
(B6.5XFAD x BXD65)F1-Ntg f 53.5188 6.7167 66.7555 40.282
(B6.5XFAD x BXD65)F1-Ntg m 88.2 13.4335 114.6734 61.7266
(B6.5XFAD x BXD66)F1-ADtg f 31.0367 10.9684 52.6521 9.4212
(B6.5XFAD x BXD66)F1-ADtg m 27.584 8.4961 44.3273 10.8407
(B6.5XFAD x BXD68)F1-ADtg f 47.29 10.9684 68.9055 25.6745
(B6.5XFAD x BXD68)F1-ADtg m 44.1029 7.1805 58.2535 29.9522
(B6.5XFAD x BXD68)F1-Ntg f 53.426 6.0076 65.2653 41.5867
(B6.5XFAD x BXD68)F1-Ntg m 54.425 13.4335 80.8984 27.9516
(B6.5XFAD x BXD69)F1-ADtg f 27.17 7.7558 42.4544 11.8856
(B6.5XFAD x BXD69)F1-ADtg m 37.792 8.4961 54.5353 21.0487
(B6.5XFAD x BXD69)F1-Ntg f 29.25 9.4989 47.9695 10.5305
(B6.5XFAD x BXD69)F1-Ntg m 40.3467 7.7558 55.6311 25.0622
(B6.5XFAD x BXD70)F1-Ntg f 54.44 10.9684 76.0555 32.8245
(B6.5XFAD x BXD70)F1-Ntg m 30.335 13.4335 56.8084 3.8616
(B6.5XFAD x BXD75)F1-ADtg f 2.2225 9.4989 20.942 -16.497
(B6.5XFAD x BXD75)F1-ADtg m 11.12 9.4989 29.8395 -7.5995
(B6.5XFAD x BXD77)F1-ADtg f 0.0 10.9684 21.6155 -21.6155
(B6.5XFAD x BXD77)F1-ADtg m 29.77 10.9684 51.3855 8.1545
(B6.5XFAD x BXD77)F1-Ntg f 28.233 6.0076 40.0723 16.3937
(B6.5XFAD x BXD77)F1-Ntg m 26.2817 7.7558 41.5661 10.9972
(B6.5XFAD x BXD87)F1-ADtg f 28.518 6.0076 40.3573 16.6787
(B6.5XFAD x BXD87)F1-ADtg m 34.855 9.4989 53.5745 16.1355
(B6.5XFAD x BXD89)F1-Ntg f 60.485 13.4335 86.9584 34.0116
(B6.5XFAD x BXD89)F1-Ntg m 31.295 13.4335 57.7684 4.8216
(B6.5XFAD x D2)F1-ADtg f 7.3047 4.6076 16.385 -1.7756
(B6.5XFAD x D2)F1-ADtg m 9.2688 6.7167 22.5055 -3.968
(B6.5XFAD x D2)F1-Ntg f 28.6833 5.4842 39.4911 17.8756
(B6.5XFAD x D2)F1-Ntg m 29.3425 9.4989 48.062 10.623


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 58.3752 4.2694 66.789 49.9614
(B6.5XFAD x BXD100)F1-ADtg both 17.6457 7.6161 32.6547 2.6367
(B6.5XFAD x BXD100)F1-Ntg both 34.1742 6.1315 46.2576 22.0908
(B6.5XFAD x BXD32)F1-ADtg both 31.4117 8.6713 48.5002 14.3231
(B6.5XFAD x BXD32)F1-Ntg both 34.2925 8.6713 51.381 17.204
(B6.5XFAD x BXD44)F1-ADtg both 27.372 4.2684 35.7838 18.9602
(B6.5XFAD x BXD60)F1-ADtg both 22.7958 6.3721 35.3532 10.2383
(B6.5XFAD x BXD61)F1-ADtg both 25.2867 6.5549 38.2044 12.369
(B6.5XFAD x BXD61)F1-Ntg both 44.298 5.7519 55.6332 32.9628
(B6.5XFAD x BXD62)F1-ADtg both 29.7425 8.6713 46.831 12.654
(B6.5XFAD x BXD62)F1-Ntg both 74.6883 7.7558 89.9728 59.4039
(B6.5XFAD x BXD65)F1-ADtg both 47.0367 7.7558 62.3211 31.7522
(B6.5XFAD x BXD65)F1-Ntg both 70.8594 7.5095 85.6585 56.0603
(B6.5XFAD x BXD66)F1-ADtg both 29.3103 6.937 42.9812 15.6395
(B6.5XFAD x BXD68)F1-ADtg both 45.6964 6.5549 58.6141 32.7787
(B6.5XFAD x BXD68)F1-Ntg both 53.9255 7.3578 68.4256 39.4254
(B6.5XFAD x BXD69)F1-ADtg both 32.481 5.7519 43.8162 21.1458
(B6.5XFAD x BXD69)F1-Ntg both 34.7983 6.1315 46.8817 22.7149
(B6.5XFAD x BXD70)F1-Ntg both 42.3875 8.6713 59.476 25.299
(B6.5XFAD x BXD75)F1-ADtg both 6.6713 6.7167 19.908 -6.5655
(B6.5XFAD x BXD77)F1-ADtg both 14.885 7.7558 30.1694 -0.3994
(B6.5XFAD x BXD77)F1-Ntg both 27.2573 4.9052 36.9241 17.5906
(B6.5XFAD x BXD87)F1-ADtg both 31.6865 5.6196 42.7611 20.6119
(B6.5XFAD x BXD89)F1-Ntg both 45.89 9.4989 64.6095 27.1705
(B6.5XFAD x D2)F1-ADtg both 8.2867 4.0726 16.3127 0.2608
(B6.5XFAD x D2)F1-Ntg both 29.0129 5.4842 39.8207 18.2052




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA