Phenotype measure:   Neuner1   cfm_14mo_bin2

ID, description, units MPD:65981   cfm_14mo_bin2   percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test   [%]  2nd 2 min
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test 2nd 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means34.782   % 43.755   %
Median of the strain means33.373   % 41.0   %
SD of the strain means± 18.504 ± 19.15
Coefficient of variation (CV)0.532 0.4377
Min–max range of strain means1.56   –   85.56   % 1.78   –   91.22   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3398.9407 3398.9407 10.5788 0.0013
strain 25 72577.3261 2903.093 9.0355 < 0.0001
sex:strain 25 10944.9555 437.7982 1.3626 0.1238
Residuals 222 71327.9947 321.2973


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 53.57 21.402   27 4.1188 0.3995 11.8, 85.11 0.51
(B6.5XFAD x B6)F1-Ntg f 58.99 15.908   9 5.3028 0.2697 38.53, 79.73 1.31
(B6.5XFAD x B6)F1-Ntg m 62.88 15.6   11 4.7034 0.2481 38.31, 93.99 1.0
(B6.5XFAD x BXD100)F1-ADtg f 27.48 7.1276   2   5.04 0.2594 22.44, 32.52 -0.39
(B6.5XFAD x BXD100)F1-ADtg m 25.52 22.749   7 8.5981 0.8914 -0.95
(B6.5XFAD x BXD100)F1-Ntg f 32.535 8.2357   4 4.1179 0.2531 23.61, 41.33 -0.12
(B6.5XFAD x BXD100)F1-Ntg m 34.632 20.619   6 8.4176 0.5954 4.68, 59.11 -0.48
(B6.5XFAD x BXD14)F1-ADtg f 6.89 4.3982   2   3.11 0.6383 3.78, 10.0 -1.51
(B6.5XFAD x BXD14)F1-Ntg f 46.0 14.764   2   10.44 0.321 35.56, 56.44 0.61
(B6.5XFAD x BXD16)F1-ADtg f 48.845 19.696   4 9.848 0.4032 19.33, 59.69 0.76
(B6.5XFAD x BXD22)F1-ADtg f 37.0 52.33   2   37.0 1.4142 0.12
(B6.5XFAD x BXD22)F1-Ntg f 47.66 11.964   2   8.46 0.251 39.2, 56.12 0.7
(B6.5XFAD x BXD32)F1-ADtg f 1.56 2.2062   2   1.56 1.4142 -1.8
(B6.5XFAD x BXD32)F1-ADtg m 53.51 15.399   3 8.8906 0.2878 35.86, 64.22 0.51
(B6.5XFAD x BXD32)F1-Ntg f 14.223 12.816   3 7.3995 0.9011 2.0, 27.56 -1.11
(B6.5XFAD x BXD32)F1-Ntg m 65.51 10.748   2   7.6 0.1641 57.91, 73.11 1.14
(B6.5XFAD x BXD42)F1-ADtg f 34.335 10.84   2   7.665 0.3157 26.67, 42.0 -0.02
(B6.5XFAD x BXD42)F1-Ntg f 31.56 0.0   1   0.0 0.0 31.56, 31.56 -0.17
(B6.5XFAD x BXD44)F1-ADtg f 32.146 27.131   13 7.5248 0.844 -0.14
(B6.5XFAD x BXD44)F1-ADtg m 35.653 24.406   8 8.6289 0.6846 2.23, 70.67 -0.42
(B6.5XFAD x BXD44)F1-Ntg f 59.56 0.0   1   0.0 0.0 59.56, 59.56 1.34
(B6.5XFAD x BXD44)F1-Ntg m 31.827 11.36   3 6.5587 0.3569 20.49, 43.21 -0.62
(B6.5XFAD x BXD51)F1-ADtg f 43.675 16.158   6 6.5963 0.37 16.48, 59.56 0.48
(B6.5XFAD x BXD51)F1-Ntg f 55.37 34.983   4 17.492 0.6318 4.0, 82.44 1.11
(B6.5XFAD x BXD55)F1-ADtg f 15.415 22.874   4 11.437 1.4839 -1.05
(B6.5XFAD x BXD55)F1-Ntg f 16.815 8.6621   2   6.125 0.5151 10.69, 22.94 -0.97
(B6.5XFAD x BXD56)F1-ADtg m 61.11 0.0   1   0.0 0.0 61.11, 61.11 0.91
(B6.5XFAD x BXD56)F1-Ntg f 34.185 45.516   2   32.185 1.3315 2.0, 66.37 -0.03
(B6.5XFAD x BXD56)F1-Ntg m 1.78 0.0   1   0.0 0.0 1.78, 1.78 -2.19
(B6.5XFAD x BXD60)F1-ADtg f 23.75 17.148   4 8.5738 0.722 2.67, 44.67 -0.6
(B6.5XFAD x BXD60)F1-ADtg m 32.064 13.019   5 5.8223 0.406 16.44, 45.66 -0.61
(B6.5XFAD x BXD60)F1-Ntg f 41.39 10.377   3 5.9912 0.2507 29.62, 49.22 0.36
(B6.5XFAD x BXD61)F1-ADtg f 26.983 17.742   7 6.7059 0.6575 3.79, 52.89 -0.42
(B6.5XFAD x BXD61)F1-ADtg m 34.103 7.6565   3 4.4205 0.2245 28.22, 42.76 -0.5
(B6.5XFAD x BXD61)F1-Ntg f 45.422 25.641   5 11.467 0.5645 4.89, 66.59 0.58
(B6.5XFAD x BXD61)F1-Ntg m 48.702 16.917   6 6.9062 0.3474 23.61, 72.38 0.26
(B6.5XFAD x BXD62)F1-ADtg f 32.02 10.177   3 5.8755 0.3178 23.11, 43.11 -0.15
(B6.5XFAD x BXD62)F1-ADtg m 26.775 22.154   2   15.665 0.8274 11.11, 42.44 -0.89
(B6.5XFAD x BXD62)F1-Ntg f 67.02 12.62   3 7.2859 0.1883 57.33, 81.29 1.74
(B6.5XFAD x BXD62)F1-Ntg m 67.33 14.56   3 8.4063 0.2162 54.34, 83.07 1.23
(B6.5XFAD x BXD65)F1-ADtg f 43.325 29.768   6 12.153 0.6871 18.04, 84.22 0.46
(B6.5XFAD x BXD65)F1-ADtg m 74.33 17.126   2   12.11 0.2304 62.22, 86.44 1.6
(B6.5XFAD x BXD65)F1-Ntg f 63.02 22.561   8 7.9763 0.358 26.89, 87.53 1.53
(B6.5XFAD x BXD65)F1-Ntg m 91.22 5.8124   2   4.11 0.0637 87.11, 95.33 2.48
(B6.5XFAD x BXD66)F1-ADtg f 51.67 25.938   3 14.975 0.502 24.5, 76.17 0.91
(B6.5XFAD x BXD66)F1-ADtg m 30.0 10.768   5 4.8157 0.3589 12.44, 40.53 -0.72
(B6.5XFAD x BXD66)F1-Ntg f 1.56 0.0   1   0.0 0.0 1.56, 1.56 -1.8
(B6.5XFAD x BXD66)F1-Ntg m 46.697 18.676   3 10.782 0.3999 25.17, 58.57 0.15
(B6.5XFAD x BXD68)F1-ADtg f 41.06 12.945   3 7.4737 0.3153 33.18, 56.0 0.34
(B6.5XFAD x BXD68)F1-ADtg m 54.14 16.088   7 6.0807 0.2972 36.89, 85.08 0.54
(B6.5XFAD x BXD68)F1-Ntg f 63.61 18.519   10 5.8561 0.2911 28.89, 93.1 1.56
(B6.5XFAD x BXD68)F1-Ntg m 65.83 34.5   2   24.395 0.5241 41.43, 90.22 1.15
(B6.5XFAD x BXD69)F1-ADtg f 18.12 10.611   6 4.3318 0.5856 9.33, 36.22 -0.9
(B6.5XFAD x BXD69)F1-ADtg m 42.012 19.148   5 8.5634 0.4558 10.47, 59.69 -0.09
(B6.5XFAD x BXD69)F1-Ntg f 38.665 12.142   4 6.0711 0.314 27.62, 56.0 0.21
(B6.5XFAD x BXD69)F1-Ntg m 41.632 22.18   6 9.0549 0.5328 19.33, 71.27 -0.11
(B6.5XFAD x BXD70)F1-ADtg f 30.0 0.0   1   0.0 0.0 30.0, 30.0 -0.26
(B6.5XFAD x BXD70)F1-ADtg m 40.147 21.738   3 12.55 0.5415 15.11, 54.22 -0.19
(B6.5XFAD x BXD70)F1-Ntg f 44.783 25.264   3 14.586 0.5641 15.78, 62.0 0.54
(B6.5XFAD x BXD70)F1-Ntg m 62.81 26.142   2   18.485 0.4162 44.32, 81.29 1.0
(B6.5XFAD x BXD75)F1-ADtg f 2.95 4.663   4 2.3315 1.5807 -1.72
(B6.5XFAD x BXD75)F1-ADtg m 18.925 16.953   4 8.4765 0.8958 3.11, 42.32 -1.3
(B6.5XFAD x BXD75)F1-Ntg f 25.737 12.061   6 4.9238 0.4686 5.78, 38.98 -0.49
(B6.5XFAD x BXD75)F1-Ntg m 63.03 0.0   1   0.0 0.0 63.03, 63.03 1.01
(B6.5XFAD x BXD77)F1-ADtg f 2.5233 4.3705   3 2.5233 1.7321 -1.74
(B6.5XFAD x BXD77)F1-ADtg m 21.877 9.9888   3 5.767 0.4566 16.0, 33.41 -1.14
(B6.5XFAD x BXD77)F1-Ntg f 34.009 11.864   10 3.7518 0.3489 14.48, 53.01 -0.04
(B6.5XFAD x BXD77)F1-Ntg m 30.778 20.525   6 8.3792 0.6669 10.67, 68.15 -0.68
(B6.5XFAD x BXD81)F1-ADtg f 22.722 13.198   6 5.3879 0.5808 8.44, 44.22 -0.65
(B6.5XFAD x BXD81)F1-Ntg f 32.702 20.362   5 9.1062 0.6227 14.22, 66.0 -0.11
(B6.5XFAD x BXD87)F1-ADtg f 25.682 10.988   10 3.4748 0.4279 8.69, 44.1 -0.49
(B6.5XFAD x BXD87)F1-ADtg m 38.733 15.292   4 7.646 0.3948 24.28, 59.47 -0.26
(B6.5XFAD x BXD87)F1-Ntg f 32.417 27.741   3 16.016 0.8558 4.23, 59.69 -0.13
(B6.5XFAD x BXD87)F1-Ntg m 62.14 0.0   1   0.0 0.0 62.14, 62.14 0.96
(B6.5XFAD x BXD89)F1-ADtg m 22.67 0.0   1   0.0 0.0 22.67, 22.67 -1.1
(B6.5XFAD x BXD89)F1-Ntg f 51.18 16.122   2   11.4 0.315 39.78, 62.58 0.89
(B6.5XFAD x BXD89)F1-Ntg m 41.0 7.0711   2   5.0 0.1725 36.0, 46.0 -0.14
(B6.5XFAD x BXD99)F1-ADtg f 85.56 0.0   1   0.0 0.0 85.56, 85.56 2.74
(B6.5XFAD x BXD99)F1-Ntg f 35.56 0.0   1   0.0 0.0 35.56, 35.56 0.04
(B6.5XFAD x D2)F1-ADtg f 9.1335 13.986   17 3.3922 1.5313 -1.39
(B6.5XFAD x D2)F1-ADtg m 18.04 11.128   8 3.9344 0.6169 -1.34
(B6.5XFAD x D2)F1-Ntg f 32.737 15.299   12 4.4165 0.4673 14.92, 65.7 -0.11
(B6.5XFAD x D2)F1-Ntg m 30.445 25.805   4 12.902 0.8476 1.33, 64.0 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 58.9889 5.9749 70.7637 47.2141
(B6.5XFAD x B6)F1-Ntg m 62.8818 5.4045 73.5325 52.2311
(B6.5XFAD x BXD100)F1-ADtg f 27.48 12.6747 52.4582 2.5018
(B6.5XFAD x BXD100)F1-ADtg m 25.52 6.7749 38.8714 12.1686
(B6.5XFAD x BXD100)F1-Ntg f 32.535 8.9624 50.1972 14.8728
(B6.5XFAD x BXD100)F1-Ntg m 34.6317 7.3178 49.0528 20.2105
(B6.5XFAD x BXD32)F1-ADtg f 1.56 12.6747 26.5382 -23.4182
(B6.5XFAD x BXD32)F1-ADtg m 53.5067 10.3489 73.9013 33.1121
(B6.5XFAD x BXD32)F1-Ntg f 14.2233 10.3489 34.6179 -6.1713
(B6.5XFAD x BXD32)F1-Ntg m 65.51 12.6747 90.4882 40.5318
(B6.5XFAD x BXD44)F1-ADtg f 32.1462 4.9714 41.9434 22.3489
(B6.5XFAD x BXD44)F1-ADtg m 35.6525 6.3374 48.1416 23.1634
(B6.5XFAD x BXD60)F1-ADtg f 23.75 8.9624 41.4122 6.0878
(B6.5XFAD x BXD60)F1-ADtg m 32.064 8.0162 47.8616 16.2664
(B6.5XFAD x BXD61)F1-ADtg f 26.9829 6.7749 40.3343 13.6315
(B6.5XFAD x BXD61)F1-ADtg m 34.1033 10.3489 54.4979 13.7087
(B6.5XFAD x BXD61)F1-Ntg f 45.422 8.0162 61.2196 29.6244
(B6.5XFAD x BXD61)F1-Ntg m 48.7017 7.3178 63.1228 34.2805
(B6.5XFAD x BXD62)F1-ADtg f 32.02 10.3489 52.4146 11.6254
(B6.5XFAD x BXD62)F1-ADtg m 26.775 12.6747 51.7532 1.7968
(B6.5XFAD x BXD62)F1-Ntg f 67.02 10.3489 87.4146 46.6254
(B6.5XFAD x BXD62)F1-Ntg m 67.3333 10.3489 87.7279 46.9387
(B6.5XFAD x BXD65)F1-ADtg f 43.325 7.3178 57.7462 28.9038
(B6.5XFAD x BXD65)F1-ADtg m 74.33 12.6747 99.3082 49.3518
(B6.5XFAD x BXD65)F1-Ntg f 63.0175 6.3374 75.5066 50.5284
(B6.5XFAD x BXD65)F1-Ntg m 91.22 12.6747 116.1982 66.2418
(B6.5XFAD x BXD66)F1-ADtg f 51.67 10.3489 72.0646 31.2754
(B6.5XFAD x BXD66)F1-ADtg m 30.0 8.0162 45.7976 14.2024
(B6.5XFAD x BXD68)F1-ADtg f 41.06 10.3489 61.4546 20.6654
(B6.5XFAD x BXD68)F1-ADtg m 54.1386 6.7749 67.49 40.7872
(B6.5XFAD x BXD68)F1-Ntg f 63.611 5.6683 74.7816 52.4404
(B6.5XFAD x BXD68)F1-Ntg m 65.825 12.6747 90.8032 40.8468
(B6.5XFAD x BXD69)F1-ADtg f 18.12 7.3178 32.5412 3.6988
(B6.5XFAD x BXD69)F1-ADtg m 42.012 8.0162 57.8096 26.2144
(B6.5XFAD x BXD69)F1-Ntg f 38.665 8.9624 56.3272 21.0028
(B6.5XFAD x BXD69)F1-Ntg m 41.6317 7.3178 56.0528 27.2105
(B6.5XFAD x BXD70)F1-Ntg f 44.7833 10.3489 65.1779 24.3887
(B6.5XFAD x BXD70)F1-Ntg m 62.805 12.6747 87.7832 37.8268
(B6.5XFAD x BXD75)F1-ADtg f 2.95 8.9624 20.6122 -14.7122
(B6.5XFAD x BXD75)F1-ADtg m 18.925 8.9624 36.5872 1.2628
(B6.5XFAD x BXD77)F1-ADtg f 2.5233 10.3489 22.9179 -17.8713
(B6.5XFAD x BXD77)F1-ADtg m 21.8767 10.3489 42.2713 1.4821
(B6.5XFAD x BXD77)F1-Ntg f 34.009 5.6683 45.1796 22.8384
(B6.5XFAD x BXD77)F1-Ntg m 30.7783 7.3178 45.1995 16.3572
(B6.5XFAD x BXD87)F1-ADtg f 25.682 5.6683 36.8526 14.5114
(B6.5XFAD x BXD87)F1-ADtg m 38.7325 8.9624 56.3947 21.0703
(B6.5XFAD x BXD89)F1-Ntg f 51.18 12.6747 76.1582 26.2018
(B6.5XFAD x BXD89)F1-Ntg m 41.0 12.6747 65.9782 16.0218
(B6.5XFAD x D2)F1-ADtg f 9.1335 4.3474 17.701 0.5661
(B6.5XFAD x D2)F1-ADtg m 18.04 6.3374 30.5291 5.5509
(B6.5XFAD x D2)F1-Ntg f 32.7367 5.1744 42.934 22.5394
(B6.5XFAD x D2)F1-Ntg m 30.445 8.9624 48.1072 12.7828


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 60.9354 4.0283 68.8739 52.9968
(B6.5XFAD x BXD100)F1-ADtg both 26.5 7.1859 40.6613 12.3387
(B6.5XFAD x BXD100)F1-Ntg both 33.5833 5.7852 44.9843 22.1824
(B6.5XFAD x BXD32)F1-ADtg both 27.5333 8.1815 43.6567 11.41
(B6.5XFAD x BXD32)F1-Ntg both 39.8667 8.1815 55.99 23.7433
(B6.5XFAD x BXD44)F1-ADtg both 33.8993 4.0273 41.836 25.9627
(B6.5XFAD x BXD60)F1-ADtg both 27.907 6.0121 39.7552 16.0588
(B6.5XFAD x BXD61)F1-ADtg both 30.5431 6.1846 42.7312 18.355
(B6.5XFAD x BXD61)F1-Ntg both 47.0618 5.427 57.7568 36.3668
(B6.5XFAD x BXD62)F1-ADtg both 29.3975 8.1815 45.5208 13.2742
(B6.5XFAD x BXD62)F1-Ntg both 67.1767 7.3178 81.5978 52.7555
(B6.5XFAD x BXD65)F1-ADtg both 58.8275 7.3178 73.2487 44.4063
(B6.5XFAD x BXD65)F1-Ntg both 77.1188 7.0854 91.082 63.1555
(B6.5XFAD x BXD66)F1-ADtg both 40.835 6.5452 53.7337 27.9363
(B6.5XFAD x BXD68)F1-ADtg both 47.5993 6.1846 59.7874 35.4112
(B6.5XFAD x BXD68)F1-Ntg both 64.718 6.9422 78.3991 51.0369
(B6.5XFAD x BXD69)F1-ADtg both 30.066 5.427 40.761 19.371
(B6.5XFAD x BXD69)F1-Ntg both 40.1483 5.7852 51.5493 28.7474
(B6.5XFAD x BXD70)F1-Ntg both 53.7942 8.1815 69.9175 37.6708
(B6.5XFAD x BXD75)F1-ADtg both 10.9375 6.3374 23.4266 -1.5516
(B6.5XFAD x BXD77)F1-ADtg both 12.2 7.3178 26.6212 -2.2212
(B6.5XFAD x BXD77)F1-Ntg both 32.3937 4.6282 41.5144 23.2729
(B6.5XFAD x BXD87)F1-ADtg both 32.2073 5.3022 42.6564 21.7581
(B6.5XFAD x BXD89)F1-Ntg both 46.09 8.9624 63.7522 28.4278
(B6.5XFAD x D2)F1-ADtg both 13.5868 3.8426 21.1594 6.0141
(B6.5XFAD x D2)F1-Ntg both 31.5908 5.1744 41.7881 21.3935




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA