Phenotype measure:   Neuner1   cfm_14mo_bin1

ID, description, units MPD:65980   cfm_14mo_bin1   percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test   [%]  1st 2 min
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 14 mo of age, day 2 contextual fear memory, 10 min test 1st 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means24.383   % 31.61   %
Median of the strain means23.571   % 29.768   %
SD of the strain means± 16.769 ± 15.961
Coefficient of variation (CV)0.6877 0.5049
Min–max range of strain means0.0   –   71.71   % 0.0   –   71.94   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1789.1204 1789.1204 6.2231 0.0133
strain 25 46665.9216 1866.6369 6.4927 < 0.0001
sex:strain 25 10809.6592 432.3864 1.504 0.0644
Residuals 222 63824.3812 287.4972


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 45.059 17.547   27 3.3769 0.3894 15.14, 78.22 0.84
(B6.5XFAD x B6)F1-Ntg f 50.67 14.242   9 4.7475 0.2811 27.62, 67.93 1.57
(B6.5XFAD x B6)F1-Ntg m 48.242 12.044   11 3.6313 0.2497 24.94, 67.71 1.04
(B6.5XFAD x BXD100)F1-ADtg f 5.23 3.3093   2   2.34 0.6327 2.89, 7.57 -1.14
(B6.5XFAD x BXD100)F1-ADtg m 15.966 17.034   7 6.4384 1.0669 -0.98
(B6.5XFAD x BXD100)F1-Ntg f 24.578 22.911   4 11.455 0.9322 0.89, 52.44 0.01
(B6.5XFAD x BXD100)F1-Ntg m 29.768 19.594   6 7.9993 0.6582 7.35, 56.35 -0.12
(B6.5XFAD x BXD14)F1-ADtg f 3.005 4.2497   2   3.005 1.4142 -1.27
(B6.5XFAD x BXD14)F1-Ntg f 21.935 11.179   2   7.905 0.5097 14.03, 29.84 -0.15
(B6.5XFAD x BXD16)F1-ADtg f 30.367 11.9   4 5.95 0.3919 19.11, 42.98 0.36
(B6.5XFAD x BXD22)F1-ADtg f 34.52 48.819   2   34.52 1.4142 0.6
(B6.5XFAD x BXD22)F1-Ntg f 27.885 16.186   2   11.445 0.5804 16.44, 39.33 0.21
(B6.5XFAD x BXD32)F1-ADtg f 1.335 1.888   2   1.335 1.4142 -1.37
(B6.5XFAD x BXD32)F1-ADtg m 45.953 13.024   3 7.5191 0.2834 34.52, 60.13 0.9
(B6.5XFAD x BXD32)F1-Ntg f 3.6367 2.0671   3 1.1934 0.5684 2.23, 6.01 -1.24
(B6.5XFAD x BXD32)F1-Ntg m 51.89 16.377   2   11.58 0.3156 40.31, 63.47 1.27
(B6.5XFAD x BXD42)F1-ADtg f 13.03 15.274   2   10.8 1.1722 2.23, 23.83 -0.68
(B6.5XFAD x BXD42)F1-Ntg f 13.81 0.0   1   0.0 0.0 13.81, 13.81 -0.63
(B6.5XFAD x BXD44)F1-ADtg f 22.357 18.757   13 5.2022 0.839 -0.12
(B6.5XFAD x BXD44)F1-ADtg m 28.922 23.452   8 8.2915 0.8109 0.89, 62.36 -0.17
(B6.5XFAD x BXD44)F1-Ntg f 36.08 0.0   1   0.0 0.0 36.08, 36.08 0.7
(B6.5XFAD x BXD44)F1-Ntg m 20.597 23.091   3 13.331 1.1211 4.9, 47.11 -0.69
(B6.5XFAD x BXD51)F1-ADtg f 28.227 14.707   6 6.0042 0.521 1.11, 38.53 0.23
(B6.5XFAD x BXD51)F1-Ntg f 49.24 29.124   4 14.562 0.5915 7.13, 71.27 1.48
(B6.5XFAD x BXD55)F1-ADtg f 4.0 8.0   4 4.0 2.0 -1.22
(B6.5XFAD x BXD55)F1-Ntg f 17.78 4.0871   2   2.89 0.2299 14.89, 20.67 -0.39
(B6.5XFAD x BXD56)F1-ADtg m 34.52 0.0   1   0.0 0.0 34.52, 34.52 0.18
(B6.5XFAD x BXD56)F1-Ntg f 18.335 25.93   2   18.335 1.4142 -0.36
(B6.5XFAD x BXD56)F1-Ntg m 0.0 0.0   1   0.0 None -1.98
(B6.5XFAD x BXD60)F1-ADtg f 7.735 6.5342   4 3.2671 0.8448 0.89, 16.48 -0.99
(B6.5XFAD x BXD60)F1-ADtg m 22.752 10.638   5 4.7576 0.4676 7.8, 34.52 -0.55
(B6.5XFAD x BXD60)F1-Ntg f 34.51 18.505   3 10.684 0.5362 16.0, 53.01 0.6
(B6.5XFAD x BXD61)F1-ADtg f 15.781 13.835   7 5.2291 0.8767 -0.51
(B6.5XFAD x BXD61)F1-ADtg m 24.473 10.999   3 6.3503 0.4494 13.81, 35.78 -0.45
(B6.5XFAD x BXD61)F1-Ntg f 40.532 25.27   5 11.301 0.6235 0.89, 66.44 0.96
(B6.5XFAD x BXD61)F1-Ntg m 36.393 23.497   6 9.5927 0.6456 12.47, 68.89 0.3
(B6.5XFAD x BXD62)F1-ADtg f 25.09 11.85   3 6.8415 0.4723 12.69, 36.3 0.04
(B6.5XFAD x BXD62)F1-ADtg m 9.69 8.9803   2   6.35 0.9268 3.34, 16.04 -1.37
(B6.5XFAD x BXD62)F1-Ntg f 71.27 12.748   3 7.3602 0.1789 63.25, 85.97 2.8
(B6.5XFAD x BXD62)F1-Ntg m 52.33 8.738   3 5.0449 0.167 43.88, 61.33 1.3
(B6.5XFAD x BXD65)F1-ADtg f 23.815 19.273   6 7.8683 0.8093 4.67, 48.33 -0.03
(B6.5XFAD x BXD65)F1-ADtg m 58.36 20.471   2   14.475 0.3508 43.88, 72.83 1.68
(B6.5XFAD x BXD65)F1-Ntg f 46.926 25.258   8 8.9301 0.5383 10.47, 77.95 1.34
(B6.5XFAD x BXD65)F1-Ntg m 71.94 13.859   2   9.8 0.1927 62.14, 81.74 2.53
(B6.5XFAD x BXD66)F1-ADtg f 35.187 25.335   3 14.627 0.72 9.56, 60.22 0.64
(B6.5XFAD x BXD66)F1-ADtg m 23.448 13.03   5 5.8271 0.5557 5.57, 37.78 -0.51
(B6.5XFAD x BXD66)F1-Ntg f 4.45 0.0   1   0.0 0.0 4.45, 4.45 -1.19
(B6.5XFAD x BXD66)F1-Ntg m 34.667 22.118   3 12.77 0.638 10.44, 53.78 0.19
(B6.5XFAD x BXD68)F1-ADtg f 20.1 10.599   3 6.1192 0.5273 8.02, 27.84 -0.26
(B6.5XFAD x BXD68)F1-ADtg m 35.773 20.044   7 7.5759 0.5603 6.67, 62.67 0.26
(B6.5XFAD x BXD68)F1-Ntg f 46.053 23.866   10 7.5471 0.5182 8.46, 78.89 1.29
(B6.5XFAD x BXD68)F1-Ntg m 43.865 50.72   2   35.865 1.1563 8.0, 79.73 0.77
(B6.5XFAD x BXD69)F1-ADtg f 27.898 12.221   6 4.9892 0.4381 14.03, 41.87 0.21
(B6.5XFAD x BXD69)F1-ADtg m 33.442 17.186   5 7.6856 0.5139 17.78, 52.22 0.11
(B6.5XFAD x BXD69)F1-Ntg f 29.705 14.412   4 7.206 0.4852 17.15, 49.67 0.32
(B6.5XFAD x BXD69)F1-Ntg m 27.117 19.967   6 8.1517 0.7364 5.57, 54.0 -0.28
(B6.5XFAD x BXD70)F1-ADtg f 4.45 0.0   1   0.0 0.0 4.45, 4.45 -1.19
(B6.5XFAD x BXD70)F1-ADtg m 36.08 10.679   3 6.1657 0.296 28.73, 48.33 0.28
(B6.5XFAD x BXD70)F1-Ntg f 31.153 2.4427   3 1.4103 0.0784 28.95, 33.78 0.4
(B6.5XFAD x BXD70)F1-Ntg m 22.83 32.286   2   22.83 1.4142 -0.55
(B6.5XFAD x BXD75)F1-ADtg f 3.0075 6.015   4 3.0075 2.0 -1.27
(B6.5XFAD x BXD75)F1-ADtg m 20.398 14.138   4 7.0688 0.6931 3.56, 33.78 -0.7
(B6.5XFAD x BXD75)F1-Ntg f 26.14 18.117   6 7.3964 0.6931 1.56, 47.88 0.1
(B6.5XFAD x BXD75)F1-Ntg m 32.67 0.0   1   0.0 0.0 32.67, 32.67 0.07
(B6.5XFAD x BXD77)F1-ADtg f 0.0 0.0   3 0.0 None -1.45
(B6.5XFAD x BXD77)F1-ADtg m 18.75 9.7309   3 5.6182 0.519 10.69, 29.56 -0.81
(B6.5XFAD x BXD77)F1-Ntg f 23.326 15.016   10 4.7485 0.6437 4.44, 51.22 -0.06
(B6.5XFAD x BXD77)F1-Ntg m 24.32 15.096   6 6.163 0.6207 11.36, 48.22 -0.46
(B6.5XFAD x BXD81)F1-ADtg f 6.5667 7.0273   6 2.8689 1.0701 -1.06
(B6.5XFAD x BXD81)F1-Ntg f 29.932 23.938   5 10.705 0.7997 4.68, 60.44 0.33
(B6.5XFAD x BXD87)F1-ADtg f 20.305 9.9581   10 3.149 0.4904 2.44, 40.89 -0.24
(B6.5XFAD x BXD87)F1-ADtg m 31.073 13.949   4 6.9743 0.4489 17.78, 49.56 -0.03
(B6.5XFAD x BXD87)F1-Ntg f 22.967 36.511   3 21.08 1.5897 0.89, 65.11 -0.08
(B6.5XFAD x BXD87)F1-Ntg m 61.78 0.0   1   0.0 0.0 61.78, 61.78 1.89
(B6.5XFAD x BXD89)F1-ADtg m 8.46 0.0   1   0.0 0.0 8.46, 8.46 -1.45
(B6.5XFAD x BXD89)F1-Ntg f 38.92 20.704   2   14.64 0.532 24.28, 53.56 0.87
(B6.5XFAD x BXD89)F1-Ntg m 19.265 14.644   2   10.355 0.7601 8.91, 29.62 -0.77
(B6.5XFAD x BXD99)F1-ADtg f 71.71 0.0   1   0.0 0.0 71.71, 71.71 2.82
(B6.5XFAD x BXD99)F1-Ntg f 26.73 0.0   1   0.0 0.0 26.73, 26.73 0.14
(B6.5XFAD x D2)F1-ADtg f 7.5524 11.365   17 2.7563 1.5048 -1.0
(B6.5XFAD x D2)F1-ADtg m 10.434 6.4021   8 2.2635 0.6136 -1.33
(B6.5XFAD x D2)F1-Ntg f 22.546 20.056   12 5.7898 0.8896 3.56, 56.79 -0.11
(B6.5XFAD x D2)F1-Ntg m 25.113 17.264   4 8.6319 0.6875 2.9, 44.54 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 50.6689 5.6519 61.8072 39.5306
(B6.5XFAD x B6)F1-Ntg m 48.2418 5.1123 58.3168 38.1669
(B6.5XFAD x BXD100)F1-ADtg f 5.23 11.9895 28.8578 -18.3978
(B6.5XFAD x BXD100)F1-ADtg m 15.9657 6.4087 28.5953 3.3361
(B6.5XFAD x BXD100)F1-Ntg f 24.5775 8.4779 41.2849 7.8701
(B6.5XFAD x BXD100)F1-Ntg m 29.7683 6.9222 43.4099 16.1268
(B6.5XFAD x BXD32)F1-ADtg f 1.335 11.9895 24.9628 -22.2928
(B6.5XFAD x BXD32)F1-ADtg m 45.9533 9.7894 65.2454 26.6613
(B6.5XFAD x BXD32)F1-Ntg f 3.6367 9.7894 22.9287 -15.6554
(B6.5XFAD x BXD32)F1-Ntg m 51.89 11.9895 75.5178 28.2622
(B6.5XFAD x BXD44)F1-ADtg f 22.3569 4.7027 31.6245 13.0893
(B6.5XFAD x BXD44)F1-ADtg m 28.9225 5.9948 40.7364 17.1086
(B6.5XFAD x BXD60)F1-ADtg f 7.735 8.4779 24.4424 -8.9724
(B6.5XFAD x BXD60)F1-ADtg m 22.752 7.5828 37.6956 7.8084
(B6.5XFAD x BXD61)F1-ADtg f 15.7814 6.4087 28.411 3.1518
(B6.5XFAD x BXD61)F1-ADtg m 24.4733 9.7894 43.7654 5.1813
(B6.5XFAD x BXD61)F1-Ntg f 40.532 7.5828 55.4756 25.5884
(B6.5XFAD x BXD61)F1-Ntg m 36.3933 6.9222 50.0349 22.7518
(B6.5XFAD x BXD62)F1-ADtg f 25.09 9.7894 44.382 5.798
(B6.5XFAD x BXD62)F1-ADtg m 9.69 11.9895 33.3178 -13.9378
(B6.5XFAD x BXD62)F1-Ntg f 71.27 9.7894 90.562 51.978
(B6.5XFAD x BXD62)F1-Ntg m 52.33 9.7894 71.622 33.038
(B6.5XFAD x BXD65)F1-ADtg f 23.815 6.9222 37.4565 10.1735
(B6.5XFAD x BXD65)F1-ADtg m 58.355 11.9895 81.9828 34.7272
(B6.5XFAD x BXD65)F1-Ntg f 46.9262 5.9948 58.7402 35.1123
(B6.5XFAD x BXD65)F1-Ntg m 71.94 11.9895 95.5678 48.3122
(B6.5XFAD x BXD66)F1-ADtg f 35.1867 9.7894 54.4787 15.8946
(B6.5XFAD x BXD66)F1-ADtg m 23.448 7.5828 38.3916 8.5044
(B6.5XFAD x BXD68)F1-ADtg f 20.1 9.7894 39.392 0.808
(B6.5XFAD x BXD68)F1-ADtg m 35.7729 6.4087 48.4025 23.1432
(B6.5XFAD x BXD68)F1-Ntg f 46.053 5.3619 56.6197 35.4863
(B6.5XFAD x BXD68)F1-Ntg m 43.865 11.9895 67.4928 20.2372
(B6.5XFAD x BXD69)F1-ADtg f 27.8983 6.9222 41.5399 14.2568
(B6.5XFAD x BXD69)F1-ADtg m 33.442 7.5828 48.3856 18.4984
(B6.5XFAD x BXD69)F1-Ntg f 29.705 8.4779 46.4124 12.9976
(B6.5XFAD x BXD69)F1-Ntg m 27.1167 6.9222 40.7582 13.4751
(B6.5XFAD x BXD70)F1-Ntg f 31.1533 9.7894 50.4454 11.8613
(B6.5XFAD x BXD70)F1-Ntg m 22.83 11.9895 46.4578 -0.7978
(B6.5XFAD x BXD75)F1-ADtg f 3.0075 8.4779 19.7149 -13.6999
(B6.5XFAD x BXD75)F1-ADtg m 20.3975 8.4779 37.1049 3.6901
(B6.5XFAD x BXD77)F1-ADtg f 0.0 9.7894 19.292 -19.292
(B6.5XFAD x BXD77)F1-ADtg m 18.75 9.7894 38.042 -0.542
(B6.5XFAD x BXD77)F1-Ntg f 23.326 5.3619 33.8927 12.7593
(B6.5XFAD x BXD77)F1-Ntg m 24.32 6.9222 37.9615 10.6785
(B6.5XFAD x BXD87)F1-ADtg f 20.305 5.3619 30.8717 9.7383
(B6.5XFAD x BXD87)F1-ADtg m 31.0725 8.4779 47.7799 14.3651
(B6.5XFAD x BXD89)F1-Ntg f 38.92 11.9895 62.5478 15.2922
(B6.5XFAD x BXD89)F1-Ntg m 19.265 11.9895 42.8928 -4.3628
(B6.5XFAD x D2)F1-ADtg f 7.5524 4.1124 15.6566 -0.5519
(B6.5XFAD x D2)F1-ADtg m 10.4337 5.9948 22.2477 -1.3802
(B6.5XFAD x D2)F1-Ntg f 22.5458 4.8947 32.1919 12.8998
(B6.5XFAD x D2)F1-Ntg m 25.1125 8.4779 41.8199 8.4051


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 49.4554 3.8105 56.9648 41.9459
(B6.5XFAD x BXD100)F1-ADtg both 10.5979 6.7974 23.9936 -2.7979
(B6.5XFAD x BXD100)F1-Ntg both 27.1729 5.4724 37.9575 16.3883
(B6.5XFAD x BXD32)F1-ADtg both 23.6442 7.7392 38.8959 8.3925
(B6.5XFAD x BXD32)F1-Ntg both 27.7633 7.7392 43.015 12.5116
(B6.5XFAD x BXD44)F1-ADtg both 25.6397 3.8096 33.1473 18.1321
(B6.5XFAD x BXD60)F1-ADtg both 15.2435 5.6871 26.4512 4.0358
(B6.5XFAD x BXD61)F1-ADtg both 20.1274 5.8503 31.6566 8.5982
(B6.5XFAD x BXD61)F1-Ntg both 38.4627 5.1336 48.5795 28.3458
(B6.5XFAD x BXD62)F1-ADtg both 17.39 7.7392 32.6417 2.1383
(B6.5XFAD x BXD62)F1-Ntg both 61.8 6.9222 75.4415 48.1585
(B6.5XFAD x BXD65)F1-ADtg both 41.085 6.9222 54.7265 27.4435
(B6.5XFAD x BXD65)F1-Ntg both 59.4331 6.7023 72.6415 46.2248
(B6.5XFAD x BXD66)F1-ADtg both 29.3173 6.1914 41.5187 17.116
(B6.5XFAD x BXD68)F1-ADtg both 27.9364 5.8503 39.4656 16.4072
(B6.5XFAD x BXD68)F1-Ntg both 44.959 6.5669 57.9005 32.0175
(B6.5XFAD x BXD69)F1-ADtg both 30.6702 5.1336 40.787 20.5533
(B6.5XFAD x BXD69)F1-Ntg both 28.4108 5.4724 39.1954 17.6263
(B6.5XFAD x BXD70)F1-Ntg both 26.9917 7.7392 42.2434 11.74
(B6.5XFAD x BXD75)F1-ADtg both 11.7025 5.9948 23.5164 -0.1114
(B6.5XFAD x BXD77)F1-ADtg both 9.375 6.9222 23.0165 -4.2665
(B6.5XFAD x BXD77)F1-Ntg both 23.823 4.378 32.4507 15.1953
(B6.5XFAD x BXD87)F1-ADtg both 25.6887 5.0156 35.573 15.8045
(B6.5XFAD x BXD89)F1-Ntg both 29.0925 8.4779 45.7999 12.3851
(B6.5XFAD x D2)F1-ADtg both 8.9931 3.6349 16.1563 1.8298
(B6.5XFAD x D2)F1-Ntg both 23.8292 4.8947 33.4752 14.1831




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA