Project measure / variable:   Neuner1   cfm_6mo_total

ID, description, units MPD:65979   cfm_6mo_total   percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test   [%]  total  
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test total



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means44.33   % 41.017   %
Median of the strain means44.867   % 40.315   %
SD of the strain means± 14.549 ± 14.572
Coefficient of variation (CV)0.3282 0.3553
Min–max range of strain means13.2   –   73.06   % 12.56   –   73.65   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 337.9177 337.9177 0.9602 0.3296
strain 13 16355.7497 1258.1346 3.5751 0.0001
sex:strain 13 2522.9491 194.073 0.5515 0.8858
Residuals 95 33431.6558 351.9122


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 54.83 15.712   2   11.11 0.2866 43.72, 65.94 0.72
(B6.5XFAD x B6)F1-ADtg m 73.65 18.511   7 6.9966 0.2514 41.74, 92.3 2.24
(B6.5XFAD x B6)F1-Ntg f 53.65 15.235   6 6.2196 0.284 27.87, 74.44 0.64
(B6.5XFAD x B6)F1-Ntg m 59.81 4.0926   4 2.0463 0.0684 56.11, 63.37 1.29
(B6.5XFAD x BXD100)F1-ADtg f 40.712 11.908   4 5.9541 0.2925 28.98, 57.19 -0.25
(B6.5XFAD x BXD100)F1-ADtg m 31.775 9.6944   2   6.855 0.3051 24.92, 38.63 -0.63
(B6.5XFAD x BXD100)F1-Ntg f 33.63 3.4365   2   2.43 0.1022 31.2, 36.06 -0.74
(B6.5XFAD x BXD14)F1-ADtg f 49.948 21.453   5 9.594 0.4295 26.27, 80.77 0.39
(B6.5XFAD x BXD14)F1-Ntg f 46.105 35.674   2   25.225 0.7737 20.88, 71.33 0.12
(B6.5XFAD x BXD16)F1-ADtg f 46.297 23.921   4 11.961 0.5167 11.04, 62.13 0.14
(B6.5XFAD x BXD22)F1-ADtg f 28.087 17.635   3 10.182 0.6279 13.67, 47.75 -1.12
(B6.5XFAD x BXD22)F1-Ntg f 38.07 0.0   1   0.0 0.0 38.07, 38.07 -0.43
(B6.5XFAD x BXD2)F1-ADtg f 51.02 32.668   4 16.334 0.6403 2.54, 73.86 0.46
(B6.5XFAD x BXD2)F1-Ntg f 52.57 17.972   5 8.0373 0.3419 23.33, 67.91 0.57
(B6.5XFAD x BXD32)F1-ADtg f 39.205 31.494   4 15.747 0.8033 1.16, 66.79 -0.35
(B6.5XFAD x BXD32)F1-ADtg m 31.145 41.458   2   29.315 1.3311 1.83, 60.46 -0.68
(B6.5XFAD x BXD32)F1-Ntg f 43.17 0.0   1   0.0 0.0 43.17, 43.17 -0.08
(B6.5XFAD x BXD32)F1-Ntg m 60.06 21.348   2   15.095 0.3554 44.97, 75.16 1.31
(B6.5XFAD x BXD34)F1-ADtg f 60.01 19.857   9 6.619 0.3309 26.63, 82.81 1.08
(B6.5XFAD x BXD34)F1-Ntg f 64.09 14.957   11 4.5098 0.2334 36.69, 86.38 1.36
(B6.5XFAD x BXD42)F1-ADtg f 55.28 16.755   6 6.8401 0.3031 22.8, 66.56 0.75
(B6.5XFAD x BXD42)F1-Ntg f 38.76 18.764   4 9.3819 0.4841 19.18, 62.97 -0.38
(B6.5XFAD x BXD44)F1-ADtg f 49.3 11.314   2   8.0 0.2295 41.3, 57.3 0.34
(B6.5XFAD x BXD44)F1-ADtg m 40.315 2.7365   2   1.935 0.0679 38.38, 42.25 -0.05
(B6.5XFAD x BXD44)F1-Ntg f 26.335 22.253   2   15.735 0.845 10.6, 42.07 -1.24
(B6.5XFAD x BXD44)F1-Ntg m 34.98 0.0   1   0.0 0.0 34.98, 34.98 -0.41
(B6.5XFAD x BXD51)F1-ADtg f 42.537 18.818   3 10.865 0.4424 20.88, 54.9 -0.12
(B6.5XFAD x BXD51)F1-Ntg f 53.98 27.605   3 15.938 0.5114 23.23, 76.63 0.66
(B6.5XFAD x BXD55)F1-ADtg f 30.173 28.75   3 16.599 0.9528 6.95, 62.33 -0.97
(B6.5XFAD x BXD55)F1-Ntg f 18.795 3.5834   4 1.7917 0.1907 15.0, 23.41 -1.76
(B6.5XFAD x BXD56)F1-ADtg f 57.77 23.158   2   16.375 0.4009 41.39, 74.14 0.92
(B6.5XFAD x BXD56)F1-Ntg f 66.15 11.836   3 6.8337 0.1789 52.49, 73.37 1.5
(B6.5XFAD x BXD60)F1-ADtg f 57.3 7.8065   2   5.52 0.1362 51.78, 62.82 0.89
(B6.5XFAD x BXD60)F1-ADtg m 33.3 10.706   2   7.57 0.3215 25.73, 40.87 -0.53
(B6.5XFAD x BXD60)F1-Ntg f 23.975 2.9911   2   2.115 0.1248 21.86, 26.09 -1.4
(B6.5XFAD x BXD61)F1-ADtg f 53.31 18.731   2   13.245 0.3513 40.07, 66.56 0.62
(B6.5XFAD x BXD61)F1-ADtg m 49.195 12.028   2   8.505 0.2445 40.69, 57.7 0.56
(B6.5XFAD x BXD61)F1-Ntg f 52.45 0.0   1   0.0 0.0 52.45, 52.45 0.56
(B6.5XFAD x BXD61)F1-Ntg m 31.26 21.157   2   14.96 0.6768 16.3, 46.22 -0.67
(B6.5XFAD x BXD62)F1-ADtg f 73.06 0.0   1   0.0 0.0 73.06, 73.06 1.97
(B6.5XFAD x BXD62)F1-ADtg m 64.83 8.6903   2   6.145 0.1341 58.68, 70.97 1.63
(B6.5XFAD x BXD62)F1-Ntg f 38.85 10.295   2   7.28 0.265 31.57, 46.13 -0.38
(B6.5XFAD x BXD62)F1-Ntg m 57.48 0.0   1   0.0 0.0 57.48, 57.48 1.13
(B6.5XFAD x BXD65)F1-ADtg f 53.13 33.567   3 19.38 0.6318 14.51, 75.29 0.6
(B6.5XFAD x BXD65)F1-ADtg m 38.895 8.2802   2   5.855 0.2129 33.04, 44.75 -0.15
(B6.5XFAD x BXD65)F1-Ntg f 68.88 0.0   1   0.0 0.0 68.88, 68.88 1.69
(B6.5XFAD x BXD65)F1-Ntg m 39.37 29.062   4 14.531 0.7382 2.45, 72.84 -0.11
(B6.5XFAD x BXD66)F1-ADtg f 15.54 0.0   1   0.0 0.0 15.54, 15.54 -1.98
(B6.5XFAD x BXD66)F1-ADtg m 42.565 20.623   4 10.311 0.4845 12.56, 59.66 0.11
(B6.5XFAD x BXD66)F1-Ntg f 36.14 0.0   1   0.0 0.0 36.14, 36.14 -0.56
(B6.5XFAD x BXD66)F1-Ntg m 12.56 0.0   1   0.0 0.0 12.56, 12.56 -1.95
(B6.5XFAD x BXD68)F1-ADtg f 66.43 20.129   6 8.2177 0.303 28.98, 87.49 1.52
(B6.5XFAD x BXD68)F1-ADtg m 33.38 0.0   1   0.0 0.0 33.38, 33.38 -0.52
(B6.5XFAD x BXD68)F1-Ntg f 46.118 23.561   9 7.8537 0.5109 13.62, 81.97 0.12
(B6.5XFAD x BXD68)F1-Ntg m 40.835 3.1183   2   2.205 0.0764 38.63, 43.04 -0.01
(B6.5XFAD x BXD69)F1-ADtg f 58.14 7.262   2   5.135 0.1249 53.0, 63.27 0.95
(B6.5XFAD x BXD69)F1-ADtg m 44.61 0.0   1   0.0 0.0 44.61, 44.61 0.25
(B6.5XFAD x BXD69)F1-Ntg f 43.63 0.0   1   0.0 0.0 43.63, 43.63 -0.05
(B6.5XFAD x BXD75)F1-ADtg f 43.615 15.163   4 7.5817 0.3477 30.77, 60.97 -0.05
(B6.5XFAD x BXD75)F1-ADtg m 44.26 7.1135   2   5.03 0.1607 39.23, 49.29 0.22
(B6.5XFAD x BXD75)F1-Ntg f 34.92 28.788   3 16.621 0.8244 15.81, 68.03 -0.65
(B6.5XFAD x BXD75)F1-Ntg m 48.4 0.0   1   0.0 0.0 48.4, 48.4 0.51
(B6.5XFAD x BXD77)F1-ADtg f 47.525 2.8638   2   2.025 0.0603 45.5, 49.55 0.22
(B6.5XFAD x BXD77)F1-ADtg m 15.09 0.0   1   0.0 0.0 15.09, 15.09 -1.78
(B6.5XFAD x BXD77)F1-Ntg f 13.2 4.0588   2   2.87 0.3075 10.33, 16.07 -2.14
(B6.5XFAD x BXD77)F1-Ntg m 16.855 5.1972   2   3.675 0.3083 13.18, 20.53 -1.66
(B6.5XFAD x BXD81)F1-ADtg f 22.72 10.079   6 4.1147 0.4436 10.32, 36.11 -1.49
(B6.5XFAD x BXD81)F1-Ntg f 38.333 12.406   3 7.1625 0.3236 30.75, 52.65 -0.41
(B6.5XFAD x BXD87)F1-ADtg f 19.493 21.708   3 12.533 1.1136 0.71, 43.26 -1.71
(B6.5XFAD x BXD87)F1-ADtg m 34.86 0.0   1   0.0 0.0 34.86, 34.86 -0.42
(B6.5XFAD x BXD87)F1-Ntg f 41.9 21.883   3 12.634 0.5223 16.87, 57.41 -0.17
(B6.5XFAD x BXD87)F1-Ntg m 53.68 22.224   3 12.831 0.414 37.31, 78.98 0.87
(B6.5XFAD x BXD99)F1-ADtg f 62.7 6.2727   3 3.6215 0.1 58.59, 69.92 1.26
(B6.5XFAD x D2)F1-ADtg f 41.286 18.679   16 4.6697 0.4524 0.94, 72.08 -0.21
(B6.5XFAD x D2)F1-ADtg m 40.378 16.103   13 4.466 0.3988 12.78, 65.36 -0.04
(B6.5XFAD x D2)F1-Ntg f 23.365 16.018   11 4.8297 0.6856 2.72, 43.61 -1.44
(B6.5XFAD x D2)F1-Ntg m 33.922 22.312   8 7.8886 0.6577 5.79, 60.52 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 54.83 13.2648 81.164 28.496
(B6.5XFAD x B6)F1-ADtg m 73.6471 7.0904 87.7233 59.571
(B6.5XFAD x B6)F1-Ntg f 53.645 7.6585 68.849 38.441
(B6.5XFAD x B6)F1-Ntg m 59.8125 9.3797 78.4335 41.1915
(B6.5XFAD x BXD100)F1-ADtg f 40.7125 9.3797 59.3335 22.0915
(B6.5XFAD x BXD100)F1-ADtg m 31.775 13.2648 58.109 5.441
(B6.5XFAD x BXD32)F1-ADtg f 39.205 9.3797 57.826 20.584
(B6.5XFAD x BXD32)F1-ADtg m 31.145 13.2648 57.479 4.811
(B6.5XFAD x BXD44)F1-ADtg f 49.3 13.2648 75.634 22.966
(B6.5XFAD x BXD44)F1-ADtg m 40.315 13.2648 66.649 13.981
(B6.5XFAD x BXD60)F1-ADtg f 57.3 13.2648 83.634 30.966
(B6.5XFAD x BXD60)F1-ADtg m 33.3 13.2648 59.634 6.966
(B6.5XFAD x BXD61)F1-ADtg f 53.315 13.2648 79.649 26.981
(B6.5XFAD x BXD61)F1-ADtg m 49.195 13.2648 75.529 22.861
(B6.5XFAD x BXD65)F1-ADtg f 53.13 10.8307 74.6317 31.6283
(B6.5XFAD x BXD65)F1-ADtg m 38.895 13.2648 65.229 12.561
(B6.5XFAD x BXD68)F1-Ntg f 46.1178 6.2531 58.5318 33.7038
(B6.5XFAD x BXD68)F1-Ntg m 40.835 13.2648 67.169 14.501
(B6.5XFAD x BXD75)F1-ADtg f 43.615 9.3797 62.236 24.994
(B6.5XFAD x BXD75)F1-ADtg m 44.26 13.2648 70.594 17.926
(B6.5XFAD x BXD77)F1-Ntg f 13.2 13.2648 39.534 -13.134
(B6.5XFAD x BXD77)F1-Ntg m 16.855 13.2648 43.189 -9.479
(B6.5XFAD x BXD87)F1-Ntg f 41.9 10.8307 63.4017 20.3983
(B6.5XFAD x BXD87)F1-Ntg m 53.68 10.8307 75.1817 32.1783
(B6.5XFAD x D2)F1-ADtg f 41.2863 4.6898 50.5967 31.9758
(B6.5XFAD x D2)F1-ADtg m 40.3777 5.2029 50.7068 30.0486
(B6.5XFAD x D2)F1-Ntg f 23.3645 5.6561 34.5934 12.1357
(B6.5XFAD x D2)F1-Ntg m 33.9225 6.6324 47.0895 20.7555


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 64.2386 7.5205 79.1686 49.3086
(B6.5XFAD x B6)F1-Ntg both 56.7288 6.0545 68.7485 44.709
(B6.5XFAD x BXD100)F1-ADtg both 36.2438 8.123 52.37 20.1175
(B6.5XFAD x BXD32)F1-ADtg both 35.175 8.123 51.3012 19.0488
(B6.5XFAD x BXD44)F1-ADtg both 44.8075 9.3797 63.4285 26.1865
(B6.5XFAD x BXD60)F1-ADtg both 45.3 9.3797 63.921 26.679
(B6.5XFAD x BXD61)F1-ADtg both 51.255 9.3797 69.876 32.634
(B6.5XFAD x BXD65)F1-ADtg both 46.0125 8.5624 63.0111 29.0139
(B6.5XFAD x BXD68)F1-Ntg both 43.4764 7.3324 58.0331 28.9197
(B6.5XFAD x BXD75)F1-ADtg both 43.9375 8.123 60.0637 27.8113
(B6.5XFAD x BXD77)F1-Ntg both 15.0275 9.3797 33.6485 -3.5935
(B6.5XFAD x BXD87)F1-Ntg both 47.79 7.6585 62.994 32.586
(B6.5XFAD x D2)F1-ADtg both 40.832 3.5023 47.7849 33.879
(B6.5XFAD x D2)F1-Ntg both 28.6435 4.3584 37.296 19.9911




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA