Phenotype measure:   Neuner1   cfm_6mo_bin4

ID, description, units MPD:65977   cfm_6mo_bin4   percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test   [%]  4th 2 min
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test 4th 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means45.719   % 40.124   %
Median of the strain means46.498   % 39.245   %
SD of the strain means± 16.294 ± 15.535
Coefficient of variation (CV)0.3564 0.3872
Min–max range of strain means13.965   –   88.2   % 13.78   –   74.0   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6039 1.6039 0.0034 0.9534
strain 13 19358.9585 1489.1507 3.1849 0.0005
sex:strain 13 3773.6101 290.2777 0.6208 0.8313
Residuals 95 44418.769 467.566


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 50.55 45.092   2   31.885 0.8919 18.67, 82.44 0.3
(B6.5XFAD x B6)F1-ADtg m 68.85 19.207   7 7.2597 0.279 43.65, 95.56 1.85
(B6.5XFAD x B6)F1-Ntg f 60.56 15.303   6 6.2476 0.2527 36.08, 77.11 0.91
(B6.5XFAD x B6)F1-Ntg m 55.61 14.102   4 7.0508 0.2536 38.08, 68.46 1.0
(B6.5XFAD x BXD100)F1-ADtg f 42.035 16.149   4 8.0746 0.3842 20.04, 56.57 -0.23
(B6.5XFAD x BXD100)F1-ADtg m 28.395 5.5084   2   3.895 0.194 24.5, 32.29 -0.75
(B6.5XFAD x BXD100)F1-Ntg f 37.37 6.8589   2   4.85 0.1835 32.52, 42.22 -0.51
(B6.5XFAD x BXD14)F1-ADtg f 61.05 19.828   5 8.8674 0.3248 37.56, 90.65 0.94
(B6.5XFAD x BXD14)F1-Ntg f 45.18 23.349   2   16.51 0.5168 28.67, 61.69 -0.03
(B6.5XFAD x BXD16)F1-ADtg f 46.125 28.452   4 14.226 0.6168 5.57, 69.27 0.02
(B6.5XFAD x BXD22)F1-ADtg f 26.273 17.539   3 10.126 0.6675 6.22, 38.75 -1.19
(B6.5XFAD x BXD22)F1-Ntg f 19.15 0.0   1   0.0 0.0 19.15, 19.15 -1.63
(B6.5XFAD x BXD2)F1-ADtg f 57.66 38.496   4 19.248 0.6677 0.73
(B6.5XFAD x BXD2)F1-Ntg f 62.04 25.277   5 11.304 0.4075 29.84, 86.0 1.0
(B6.5XFAD x BXD32)F1-ADtg f 34.202 37.463   4 18.731 1.0953 2.23, 76.0 -0.71
(B6.5XFAD x BXD32)F1-ADtg m 31.78 42.115   2   29.78 1.3252 2.0, 61.56 -0.54
(B6.5XFAD x BXD32)F1-Ntg f 35.86 0.0   1   0.0 0.0 35.86, 35.86 -0.61
(B6.5XFAD x BXD32)F1-Ntg m 54.55 24.36   2   17.225 0.4465 37.33, 71.78 0.93
(B6.5XFAD x BXD34)F1-ADtg f 60.83 22.713   9 7.5712 0.3734 17.56, 78.0 0.93
(B6.5XFAD x BXD34)F1-Ntg f 69.03 18.067   11 5.4474 0.2617 40.22, 97.77 1.43
(B6.5XFAD x BXD42)F1-ADtg f 58.09 27.461   6 11.211 0.4728 2.89, 76.67 0.76
(B6.5XFAD x BXD42)F1-Ntg f 40.1 21.976   4 10.988 0.548 15.81, 65.03 -0.34
(B6.5XFAD x BXD44)F1-ADtg f 37.135 20.075   2   14.195 0.5406 22.94, 51.33 -0.53
(B6.5XFAD x BXD44)F1-ADtg m 39.555 3.1466   2   2.225 0.0796 37.33, 41.78 -0.04
(B6.5XFAD x BXD44)F1-Ntg f 31.22 28.44   2   20.11 0.9109 11.11, 51.33 -0.89
(B6.5XFAD x BXD44)F1-Ntg m 42.32 0.0   1   0.0 0.0 42.32, 42.32 0.14
(B6.5XFAD x BXD51)F1-ADtg f 40.87 23.977   3 13.843 0.5867 13.81, 59.47 -0.3
(B6.5XFAD x BXD51)F1-Ntg f 46.87 25.582   3 14.769 0.5458 17.59, 64.89 0.07
(B6.5XFAD x BXD55)F1-ADtg f 28.977 31.334   3 18.091 1.0814 6.0, 64.67 -1.03
(B6.5XFAD x BXD55)F1-Ntg f 13.965 4.002   4 2.001 0.2866 10.47, 19.11 -1.95
(B6.5XFAD x BXD56)F1-ADtg f 60.57 33.071   2   23.385 0.546 37.19, 83.96 0.91
(B6.5XFAD x BXD56)F1-Ntg f 52.93 28.237   3 16.303 0.5335 24.22, 80.67 0.44
(B6.5XFAD x BXD60)F1-ADtg f 52.72 12.502   2   8.84 0.2371 43.88, 61.56 0.43
(B6.5XFAD x BXD60)F1-ADtg m 16.365 20.315   2   14.365 1.2414 2.0, 30.73 -1.53
(B6.5XFAD x BXD60)F1-Ntg f 36.22 15.401   2   10.89 0.4252 25.33, 47.11 -0.58
(B6.5XFAD x BXD61)F1-ADtg f 53.27 20.209   2   14.29 0.3794 38.98, 67.56 0.46
(B6.5XFAD x BXD61)F1-ADtg m 53.16 9.9843   2   7.06 0.1878 46.1, 60.22 0.84
(B6.5XFAD x BXD61)F1-Ntg f 56.0 0.0   1   0.0 0.0 56.0, 56.0 0.63
(B6.5XFAD x BXD61)F1-Ntg m 39.245 24.317   2   17.195 0.6196 22.05, 56.44 -0.06
(B6.5XFAD x BXD62)F1-ADtg f 73.11 0.0   1   0.0 0.0 73.11, 73.11 1.68
(B6.5XFAD x BXD62)F1-ADtg m 74.0 1.5698   2   1.11 0.0212 72.89, 75.11 2.18
(B6.5XFAD x BXD62)F1-Ntg f 41.67 18.385   2   13.0 0.4412 28.67, 54.67 -0.25
(B6.5XFAD x BXD62)F1-Ntg m 48.0 0.0   1   0.0 0.0 48.0, 48.0 0.51
(B6.5XFAD x BXD65)F1-ADtg f 58.81 25.658   3 14.813 0.4363 29.78, 78.44 0.8
(B6.5XFAD x BXD65)F1-ADtg m 45.22 13.039   2   9.22 0.2883 36.0, 54.44 0.33
(B6.5XFAD x BXD65)F1-Ntg f 88.2 0.0   1   0.0 0.0 88.2, 88.2 2.61
(B6.5XFAD x BXD65)F1-Ntg m 41.565 28.045   4 14.022 0.6747 3.11, 69.04 0.09
(B6.5XFAD x BXD66)F1-ADtg f 20.22 0.0   1   0.0 0.0 20.22, 20.22 -1.56
(B6.5XFAD x BXD66)F1-ADtg m 37.553 16.008   4 8.0042 0.4263 13.78, 48.67 -0.17
(B6.5XFAD x BXD66)F1-Ntg f 58.35 0.0   1   0.0 0.0 58.35, 58.35 0.78
(B6.5XFAD x BXD66)F1-Ntg m 13.78 0.0   1   0.0 0.0 13.78, 13.78 -1.7
(B6.5XFAD x BXD68)F1-ADtg f 63.79 28.403   6 11.595 0.4453 17.56, 92.44 1.11
(B6.5XFAD x BXD68)F1-ADtg m 38.75 0.0   1   0.0 0.0 38.75, 38.75 -0.09
(B6.5XFAD x BXD68)F1-Ntg f 52.8 27.836   9 9.2787 0.5272 8.91, 90.89 0.43
(B6.5XFAD x BXD68)F1-Ntg m 33.405 12.282   2   8.685 0.3677 24.72, 42.09 -0.43
(B6.5XFAD x BXD69)F1-ADtg f 47.725 5.5791   2   3.945 0.1169 43.78, 51.67 0.12
(B6.5XFAD x BXD69)F1-ADtg m 65.78 0.0   1   0.0 0.0 65.78, 65.78 1.65
(B6.5XFAD x BXD69)F1-Ntg f 67.48 0.0   1   0.0 0.0 67.48, 67.48 1.34
(B6.5XFAD x BXD75)F1-ADtg f 42.633 21.408   4 10.704 0.5022 17.82, 67.93 -0.19
(B6.5XFAD x BXD75)F1-ADtg m 36.115 0.78489   2   0.555 0.0217 35.56, 36.67 -0.26
(B6.5XFAD x BXD75)F1-Ntg f 30.733 39.77   3 22.961 1.294 6.01, 76.61 -0.92
(B6.5XFAD x BXD75)F1-Ntg m 34.22 0.0   1   0.0 0.0 34.22, 34.22 -0.38
(B6.5XFAD x BXD77)F1-ADtg f 47.555 18.859   2   13.335 0.3966 34.22, 60.89 0.11
(B6.5XFAD x BXD77)F1-ADtg m 14.48 0.0   1   0.0 0.0 14.48, 14.48 -1.65
(B6.5XFAD x BXD77)F1-Ntg f 20.91 0.59397   2   0.42 0.0284 20.49, 21.33 -1.52
(B6.5XFAD x BXD77)F1-Ntg m 18.11 1.4142   2   1.0 0.0781 17.11, 19.11 -1.42
(B6.5XFAD x BXD81)F1-ADtg f 21.802 10.995   6 4.4888 0.5043 5.57, 39.64 -1.47
(B6.5XFAD x BXD81)F1-Ntg f 36.747 7.5404   3 4.3535 0.2052 31.85, 45.43 -0.55
(B6.5XFAD x BXD87)F1-ADtg f 23.163 27.5   3 15.877 1.1872 0.89, 53.9 -1.38
(B6.5XFAD x BXD87)F1-ADtg m 33.11 0.0   1   0.0 0.0 33.11, 33.11 -0.45
(B6.5XFAD x BXD87)F1-Ntg f 51.6 27.791   3 16.045 0.5386 19.6, 69.71 0.36
(B6.5XFAD x BXD87)F1-Ntg m 48.98 26.419   3 15.253 0.5394 27.39, 78.44 0.57
(B6.5XFAD x BXD99)F1-ADtg f 63.8 7.0851   3 4.0906 0.1111 59.02, 71.94 1.11
(B6.5XFAD x D2)F1-ADtg f 40.256 22.894   16 5.7234 0.5687 -0.34
(B6.5XFAD x D2)F1-ADtg m 39.806 18.703   13 5.1873 0.4699 10.24, 70.16 -0.02
(B6.5XFAD x D2)F1-Ntg f 17.73 13.382   11 4.0348 0.7548 0.89, 34.97 -1.72
(B6.5XFAD x D2)F1-Ntg m 30.64 24.239   8 8.5697 0.7911 2.67, 68.6 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 50.555 15.29 80.9094 20.2006
(B6.5XFAD x B6)F1-ADtg m 68.8529 8.1728 85.078 52.6277
(B6.5XFAD x B6)F1-Ntg f 60.5583 8.8277 78.0835 43.0332
(B6.5XFAD x B6)F1-Ntg m 55.615 10.8116 77.0788 34.1512
(B6.5XFAD x BXD100)F1-ADtg f 42.035 10.8116 63.4988 20.5712
(B6.5XFAD x BXD100)F1-ADtg m 28.395 15.29 58.7494 -1.9594
(B6.5XFAD x BXD32)F1-ADtg f 34.2025 10.8116 55.6663 12.7387
(B6.5XFAD x BXD32)F1-ADtg m 31.78 15.29 62.1344 1.4256
(B6.5XFAD x BXD44)F1-ADtg f 37.135 15.29 67.4894 6.7806
(B6.5XFAD x BXD44)F1-ADtg m 39.555 15.29 69.9094 9.2006
(B6.5XFAD x BXD60)F1-ADtg f 52.72 15.29 83.0744 22.3656
(B6.5XFAD x BXD60)F1-ADtg m 16.365 15.29 46.7194 -13.9894
(B6.5XFAD x BXD61)F1-ADtg f 53.27 15.29 83.6244 22.9156
(B6.5XFAD x BXD61)F1-ADtg m 53.16 15.29 83.5144 22.8056
(B6.5XFAD x BXD65)F1-ADtg f 58.8133 12.4842 83.5976 34.0291
(B6.5XFAD x BXD65)F1-ADtg m 45.22 15.29 75.5744 14.8656
(B6.5XFAD x BXD68)F1-Ntg f 52.7967 7.2078 67.1059 38.4875
(B6.5XFAD x BXD68)F1-Ntg m 33.405 15.29 63.7594 3.0506
(B6.5XFAD x BXD75)F1-ADtg f 42.6325 10.8116 64.0963 21.1687
(B6.5XFAD x BXD75)F1-ADtg m 36.115 15.29 66.4694 5.7606
(B6.5XFAD x BXD77)F1-Ntg f 20.91 15.29 51.2644 -9.4444
(B6.5XFAD x BXD77)F1-Ntg m 18.11 15.29 48.4644 -12.2444
(B6.5XFAD x BXD87)F1-Ntg f 51.5967 12.4842 76.3809 26.8124
(B6.5XFAD x BXD87)F1-Ntg m 48.98 12.4842 73.7643 24.1957
(B6.5XFAD x D2)F1-ADtg f 40.2556 5.4058 50.9875 29.5237
(B6.5XFAD x D2)F1-ADtg m 39.8062 5.9972 51.7121 27.9002
(B6.5XFAD x D2)F1-Ntg f 17.73 6.5197 30.6732 4.7868
(B6.5XFAD x D2)F1-Ntg m 30.64 7.645 45.8172 15.4628


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 59.7039 8.6686 76.9133 42.4946
(B6.5XFAD x B6)F1-Ntg both 58.0867 6.9789 71.9415 44.2318
(B6.5XFAD x BXD100)F1-ADtg both 35.215 9.3632 53.8032 16.6268
(B6.5XFAD x BXD32)F1-ADtg both 32.9913 9.3632 51.5795 14.403
(B6.5XFAD x BXD44)F1-ADtg both 38.345 10.8116 59.8088 16.8812
(B6.5XFAD x BXD60)F1-ADtg both 34.5425 10.8116 56.0063 13.0787
(B6.5XFAD x BXD61)F1-ADtg both 53.215 10.8116 74.6788 31.7512
(B6.5XFAD x BXD65)F1-ADtg both 52.0167 9.8696 71.6104 32.423
(B6.5XFAD x BXD68)F1-Ntg both 43.1008 8.4518 59.8799 26.3218
(B6.5XFAD x BXD75)F1-ADtg both 39.3738 9.3632 57.962 20.7855
(B6.5XFAD x BXD77)F1-Ntg both 19.51 10.8116 40.9738 -1.9538
(B6.5XFAD x BXD87)F1-Ntg both 50.2883 8.8277 67.8135 32.7632
(B6.5XFAD x D2)F1-ADtg both 40.0309 4.037 48.0453 32.0164
(B6.5XFAD x D2)F1-Ntg both 24.185 5.0237 34.1584 14.2116




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA