Phenotype measure:   Neuner1   cfm_6mo_bin3

ID, description, units MPD:65976   cfm_6mo_bin3   percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test   [%]  3rd 2 min
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test 3rd 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means47.203   % 43.18   %
Median of the strain means48.861   % 45.495   %
SD of the strain means± 17.648 ± 15.943
Coefficient of variation (CV)0.3739 0.3692
Min–max range of strain means15.81   –   81.56   % 7.015   –   76.37   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 431.4967 431.4967 0.9847 0.3236
strain 13 19349.0851 1488.3912 3.3965 0.0003
sex:strain 13 5361.121 412.3939 0.9411 0.5146
Residuals 95 41630.8525 438.2195


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 57.02 26.778   2   18.935 0.4697 38.08, 75.95 0.56
(B6.5XFAD x B6)F1-ADtg m 76.37 19.207   7 7.2594 0.2515 40.09, 100.0 2.08
(B6.5XFAD x B6)F1-Ntg f 53.09 13.272   6 5.4181 0.25 32.22, 72.61 0.33
(B6.5XFAD x B6)F1-Ntg m 59.4 4.9083   4 2.4542 0.0826 53.12, 64.89 1.02
(B6.5XFAD x BXD100)F1-ADtg f 42.775 25.043   4 12.522 0.5855 11.33, 70.0 -0.25
(B6.5XFAD x BXD100)F1-ADtg m 32.22 10.055   2   7.11 0.3121 25.11, 39.33 -0.69
(B6.5XFAD x BXD100)F1-Ntg f 48.73 11.399   2   8.06 0.2339 40.67, 56.79 0.09
(B6.5XFAD x BXD14)F1-ADtg f 55.3 26.77   5 11.972 0.4841 17.59, 90.89 0.46
(B6.5XFAD x BXD14)F1-Ntg f 54.25 42.073   2   29.75 0.7755 24.5, 84.0 0.4
(B6.5XFAD x BXD16)F1-ADtg f 54.82 32.815   4 16.407 0.5986 5.78, 74.89 0.43
(B6.5XFAD x BXD22)F1-ADtg f 31.493 24.64   3 14.226 0.7824 14.7, 59.78 -0.89
(B6.5XFAD x BXD22)F1-Ntg f 63.56 0.0   1   0.0 0.0 63.56, 63.56 0.93
(B6.5XFAD x BXD2)F1-ADtg f 58.86 36.655   4 18.327 0.6227 4.23, 81.33 0.66
(B6.5XFAD x BXD2)F1-Ntg f 66.45 20.414   5 9.1295 0.3072 31.4, 83.07 1.09
(B6.5XFAD x BXD32)F1-ADtg f 32.477 26.343   4 13.171 0.8111 -0.83
(B6.5XFAD x BXD32)F1-ADtg m 39.195 50.08   2   35.415 1.2778 3.78, 74.61 -0.25
(B6.5XFAD x BXD32)F1-Ntg f 81.56 0.0   1   0.0 0.0 81.56, 81.56 1.95
(B6.5XFAD x BXD32)F1-Ntg m 54.01 11.809   2   8.35 0.2186 45.66, 62.36 0.68
(B6.5XFAD x BXD34)F1-ADtg f 66.11 20.924   9 6.9747 0.3165 27.17, 86.67 1.07
(B6.5XFAD x BXD34)F1-Ntg f 69.12 14.76   11 4.4503 0.2135 50.0, 93.33 1.24
(B6.5XFAD x BXD42)F1-ADtg f 58.9 22.333   6 9.1175 0.3791 17.82, 73.94 0.66
(B6.5XFAD x BXD42)F1-Ntg f 48.992 15.462   4 7.7311 0.3156 33.85, 68.67 0.1
(B6.5XFAD x BXD44)F1-ADtg f 45.735 27.287   2   19.295 0.5966 26.44, 65.03 -0.08
(B6.5XFAD x BXD44)F1-ADtg m 46.215 5.5084   2   3.895 0.1192 42.32, 50.11 0.19
(B6.5XFAD x BXD44)F1-Ntg f 24.72 18.583   2   13.14 0.7517 11.58, 37.86 -1.27
(B6.5XFAD x BXD44)F1-Ntg m 47.33 0.0   1   0.0 0.0 47.33, 47.33 0.26
(B6.5XFAD x BXD51)F1-ADtg f 41.787 21.597   3 12.469 0.5168 17.56, 59.02 -0.31
(B6.5XFAD x BXD51)F1-Ntg f 63.22 17.495   3 10.101 0.2768 44.44, 79.06 0.91
(B6.5XFAD x BXD55)F1-ADtg f 34.15 31.078   3 17.943 0.91 2.67, 64.81 -0.74
(B6.5XFAD x BXD55)F1-Ntg f 17.363 13.753   4 6.8763 0.7921 6.22, 34.74 -1.69
(B6.5XFAD x BXD56)F1-ADtg f 62.89 17.282   2   12.22 0.2748 50.67, 75.11 0.89
(B6.5XFAD x BXD56)F1-Ntg f 67.49 24.619   3 14.214 0.3648 41.2, 90.0 1.15
(B6.5XFAD x BXD60)F1-ADtg f 53.0 5.1902   2   3.67 0.0979 49.33, 56.67 0.33
(B6.5XFAD x BXD60)F1-ADtg m 45.555 20.117   2   14.225 0.4416 31.33, 59.78 0.15
(B6.5XFAD x BXD60)F1-Ntg f 29.4 6.9296   2   4.9 0.2357 24.5, 34.3 -1.01
(B6.5XFAD x BXD61)F1-ADtg f 51.52 19.742   2   13.96 0.3832 37.56, 65.48 0.24
(B6.5XFAD x BXD61)F1-ADtg m 45.495 1.492   2   1.055 0.0328 44.44, 46.55 0.15
(B6.5XFAD x BXD61)F1-Ntg f 41.87 0.0   1   0.0 0.0 41.87, 41.87 -0.3
(B6.5XFAD x BXD61)F1-Ntg m 24.26 11.681   2   8.26 0.4815 16.0, 32.52 -1.19
(B6.5XFAD x BXD62)F1-ADtg f 78.62 0.0   1   0.0 0.0 78.62, 78.62 1.78
(B6.5XFAD x BXD62)F1-ADtg m 64.92 12.756   2   9.02 0.1965 55.9, 73.94 1.36
(B6.5XFAD x BXD62)F1-Ntg f 28.505 10.076   2   7.125 0.3535 21.38, 35.63 -1.06
(B6.5XFAD x BXD62)F1-Ntg m 70.82 0.0   1   0.0 0.0 70.82, 70.82 1.73
(B6.5XFAD x BXD65)F1-ADtg f 58.95 45.291   3 26.149 0.7683 6.68, 86.64 0.67
(B6.5XFAD x BXD65)F1-ADtg m 27.395 3.783   2   2.675 0.1381 24.72, 30.07 -0.99
(B6.5XFAD x BXD65)F1-Ntg f 70.44 0.0   1   0.0 0.0 70.44, 70.44 1.32
(B6.5XFAD x BXD65)F1-Ntg m 44.735 31.586   4 15.793 0.7061 2.67, 77.51 0.1
(B6.5XFAD x BXD66)F1-ADtg f 15.81 0.0   1   0.0 0.0 15.81, 15.81 -1.78
(B6.5XFAD x BXD66)F1-ADtg m 54.22 23.707   4 11.854 0.4373 18.71, 67.93 0.69
(B6.5XFAD x BXD66)F1-Ntg f 38.44 0.0   1   0.0 0.0 38.44, 38.44 -0.5
(B6.5XFAD x BXD66)F1-Ntg m 18.71 0.0   1   0.0 0.0 18.71, 18.71 -1.53
(B6.5XFAD x BXD68)F1-ADtg f 72.1 19.693   6 8.0396 0.2731 37.42, 92.65 1.41
(B6.5XFAD x BXD68)F1-ADtg m 47.56 0.0   1   0.0 0.0 47.56, 47.56 0.27
(B6.5XFAD x BXD68)F1-Ntg f 52.39 25.093   9 8.3645 0.4789 14.22, 83.96 0.29
(B6.5XFAD x BXD68)F1-Ntg m 23.67 12.728   2   9.0 0.5377 14.67, 32.67 -1.22
(B6.5XFAD x BXD69)F1-ADtg f 75.53 0.04243   2   0.03 0.0006 75.5, 75.56 1.61
(B6.5XFAD x BXD69)F1-ADtg m 53.11 0.0   1   0.0 0.0 53.11, 53.11 0.62
(B6.5XFAD x BXD69)F1-Ntg f 26.0 0.0   1   0.0 0.0 26.0, 26.0 -1.2
(B6.5XFAD x BXD75)F1-ADtg f 40.683 19.589   4 9.7945 0.4815 17.11, 59.33 -0.37
(B6.5XFAD x BXD75)F1-ADtg m 42.315 8.8176   2   6.235 0.2084 36.08, 48.55 -0.05
(B6.5XFAD x BXD75)F1-Ntg f 38.643 29.062   3 16.779 0.7521 20.44, 72.16 -0.49
(B6.5XFAD x BXD75)F1-Ntg m 52.34 0.0   1   0.0 0.0 52.34, 52.34 0.57
(B6.5XFAD x BXD77)F1-ADtg f 45.325 3.9386   2   2.785 0.0869 42.54, 48.11 -0.11
(B6.5XFAD x BXD77)F1-ADtg m 24.67 0.0   1   0.0 0.0 24.67, 24.67 -1.16
(B6.5XFAD x BXD77)F1-Ntg f 17.02 5.2184   2   3.69 0.3066 13.33, 20.71 -1.71
(B6.5XFAD x BXD77)F1-Ntg m 7.015 5.8336   2   4.125 0.8316 2.89, 11.14 -2.27
(B6.5XFAD x BXD81)F1-ADtg f 21.965 12.158   6 4.9634 0.5535 4.22, 36.75 -1.43
(B6.5XFAD x BXD81)F1-Ntg f 29.927 13.897   3 8.0235 0.4644 15.78, 43.56 -0.98
(B6.5XFAD x BXD87)F1-ADtg f 24.297 27.708   3 15.997 1.1404 0.89, 54.89 -1.3
(B6.5XFAD x BXD87)F1-ADtg m 37.64 0.0   1   0.0 0.0 37.64, 37.64 -0.35
(B6.5XFAD x BXD87)F1-Ntg f 31.627 25.047   3 14.461 0.792 4.22, 53.33 -0.88
(B6.5XFAD x BXD87)F1-Ntg m 50.6 7.6982   3 4.4446 0.1521 45.66, 59.47 0.47
(B6.5XFAD x BXD99)F1-ADtg f 56.85 14.412   3 8.3208 0.2535 44.99, 72.89 0.55
(B6.5XFAD x D2)F1-ADtg f 41.378 20.664   16 5.1661 0.4994 -0.33
(B6.5XFAD x D2)F1-ADtg m 40.769 16.349   13 4.5343 0.401 15.11, 63.47 -0.15
(B6.5XFAD x D2)F1-Ntg f 19.017 17.601   11 5.3069 0.9255 -1.6
(B6.5XFAD x D2)F1-Ntg m 35.328 26.419   8 9.3405 0.7478 1.12, 74.67 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 57.015 14.8024 86.4014 27.6286
(B6.5XFAD x B6)F1-ADtg m 76.3729 7.9122 92.0805 60.6652
(B6.5XFAD x B6)F1-Ntg f 53.085 8.5461 70.0512 36.1188
(B6.5XFAD x B6)F1-Ntg m 59.4025 10.4668 80.1818 38.6232
(B6.5XFAD x BXD100)F1-ADtg f 42.775 10.4668 63.5543 21.9957
(B6.5XFAD x BXD100)F1-ADtg m 32.22 14.8024 61.6064 2.8336
(B6.5XFAD x BXD32)F1-ADtg f 32.4775 10.4668 53.2568 11.6982
(B6.5XFAD x BXD32)F1-ADtg m 39.195 14.8024 68.5814 9.8086
(B6.5XFAD x BXD44)F1-ADtg f 45.735 14.8024 75.1214 16.3486
(B6.5XFAD x BXD44)F1-ADtg m 46.215 14.8024 75.6014 16.8286
(B6.5XFAD x BXD60)F1-ADtg f 53.0 14.8024 82.3864 23.6136
(B6.5XFAD x BXD60)F1-ADtg m 45.555 14.8024 74.9414 16.1686
(B6.5XFAD x BXD61)F1-ADtg f 51.52 14.8024 80.9064 22.1336
(B6.5XFAD x BXD61)F1-ADtg m 45.495 14.8024 74.8814 16.1086
(B6.5XFAD x BXD65)F1-ADtg f 58.9467 12.0861 82.9406 34.9528
(B6.5XFAD x BXD65)F1-ADtg m 27.395 14.8024 56.7814 -1.9914
(B6.5XFAD x BXD68)F1-Ntg f 52.3944 6.9779 66.2473 38.5416
(B6.5XFAD x BXD68)F1-Ntg m 23.67 14.8024 53.0564 -5.7164
(B6.5XFAD x BXD75)F1-ADtg f 40.6825 10.4668 61.4618 19.9032
(B6.5XFAD x BXD75)F1-ADtg m 42.315 14.8024 71.7014 12.9286
(B6.5XFAD x BXD77)F1-Ntg f 17.02 14.8024 46.4064 -12.3664
(B6.5XFAD x BXD77)F1-Ntg m 7.015 14.8024 36.4014 -22.3714
(B6.5XFAD x BXD87)F1-Ntg f 31.6267 12.0861 55.6206 7.6328
(B6.5XFAD x BXD87)F1-Ntg m 50.6 12.0861 74.5939 26.6061
(B6.5XFAD x D2)F1-ADtg f 41.3781 5.2334 51.7678 30.9885
(B6.5XFAD x D2)F1-ADtg m 40.7692 5.806 52.2955 29.2429
(B6.5XFAD x D2)F1-Ntg f 19.0173 6.3117 31.5477 6.4869
(B6.5XFAD x D2)F1-Ntg m 35.3275 7.4012 50.0207 20.6343


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 66.6939 8.3921 83.3544 50.0334
(B6.5XFAD x B6)F1-Ntg both 56.2438 6.7563 69.6567 42.8308
(B6.5XFAD x BXD100)F1-ADtg both 37.4975 9.0646 55.4929 19.5021
(B6.5XFAD x BXD32)F1-ADtg both 35.8362 9.0646 53.8317 17.8408
(B6.5XFAD x BXD44)F1-ADtg both 45.975 10.4668 66.7543 25.1957
(B6.5XFAD x BXD60)F1-ADtg both 49.2775 10.4668 70.0568 28.4982
(B6.5XFAD x BXD61)F1-ADtg both 48.5075 10.4668 69.2868 27.7282
(B6.5XFAD x BXD65)F1-ADtg both 43.1708 9.5549 62.1397 24.202
(B6.5XFAD x BXD68)F1-Ntg both 38.0322 8.1823 54.2762 21.7883
(B6.5XFAD x BXD75)F1-ADtg both 41.4988 9.0646 59.4942 23.5033
(B6.5XFAD x BXD77)F1-Ntg both 12.0175 10.4668 32.7968 -8.7618
(B6.5XFAD x BXD87)F1-Ntg both 41.1133 8.5461 58.0796 24.1471
(B6.5XFAD x D2)F1-ADtg both 41.0737 3.9083 48.8326 33.3148
(B6.5XFAD x D2)F1-Ntg both 27.1724 4.8635 36.8277 17.5171




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA