Phenotype measure:   Neuner1   cfm_6mo_bin1

ID, description, units MPD:65974   cfm_6mo_bin1   percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test   [%]  1st 2 min
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing at 6 mo of age, day 2 contextual fear memory, 10 min test 1st 2 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means39.881   % 41.902   %
Median of the strain means42.433   % 43.915   %
SD of the strain means± 15.534 ± 17.396
Coefficient of variation (CV)0.3895 0.4152
Min–max range of strain means3.78   –   72.05   % 1.78   –   76.9   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1679.1284 1679.1284 3.5329 0.0632
strain 13 12778.6703 982.9746 2.0682 0.0231
sex:strain 13 6167.93 474.4562 0.9983 0.4593
Residuals 95 45151.4498 475.2784


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 39.27 6.8307   2   4.83 0.1739 34.44, 44.1 -0.04
(B6.5XFAD x B6)F1-ADtg m 76.9 15.976   7 6.0384 0.2077 51.33, 95.33 2.01
(B6.5XFAD x B6)F1-Ntg f 44.785 22.374   6 9.1342 0.4996 9.8, 69.04 0.32
(B6.5XFAD x B6)F1-Ntg m 58.08 17.814   4 8.9069 0.3067 40.0, 82.18 0.93
(B6.5XFAD x BXD100)F1-ADtg f 40.898 19.843   4 9.9214 0.4852 15.81, 64.22 0.07
(B6.5XFAD x BXD100)F1-ADtg m 19.67 16.815   2   11.89 0.8549 7.78, 31.56 -1.28
(B6.5XFAD x BXD100)F1-Ntg f 23.35 11.922   2   8.43 0.5106 14.92, 31.78 -1.06
(B6.5XFAD x BXD14)F1-ADtg f 28.838 20.749   5 9.2791 0.7195 10.0, 57.24 -0.71
(B6.5XFAD x BXD14)F1-Ntg f 30.23 29.529   2   20.88 0.9768 9.35, 51.11 -0.62
(B6.5XFAD x BXD16)F1-ADtg f 45.42 25.38   4 12.69 0.5588 7.78, 63.33 0.36
(B6.5XFAD x BXD22)F1-ADtg f 33.57 25.607   3 14.784 0.7628 14.48, 62.67 -0.41
(B6.5XFAD x BXD22)F1-Ntg f 50.44 0.0   1   0.0 0.0 50.44, 50.44 0.68
(B6.5XFAD x BXD2)F1-ADtg f 35.913 23.953   4 11.977 0.667 2.45, 56.79 -0.26
(B6.5XFAD x BXD2)F1-Ntg f 40.91 25.314   5 11.321 0.6188 0.07
(B6.5XFAD x BXD32)F1-ADtg f 46.222 32.982   4 16.491 0.7135 0.89, 73.11 0.41
(B6.5XFAD x BXD32)F1-ADtg m 30.065 42.518   2   30.065 1.4142 -0.68
(B6.5XFAD x BXD32)F1-Ntg f 29.11 0.0   1   0.0 0.0 29.11, 29.11 -0.69
(B6.5XFAD x BXD32)F1-Ntg m 54.45 29.225   2   20.665 0.5368 33.78, 75.11 0.72
(B6.5XFAD x BXD34)F1-ADtg f 54.38 21.754   9 7.2515 0.4001 20.89, 81.11 0.93
(B6.5XFAD x BXD34)F1-Ntg f 50.84 24.198   11 7.296 0.476 5.35, 78.44 0.71
(B6.5XFAD x BXD42)F1-ADtg f 43.958 9.2175   6 3.763 0.2097 28.22, 53.01 0.26
(B6.5XFAD x BXD42)F1-Ntg f 23.177 28.474   4 14.237 1.2285 2.89, 64.0 -1.08
(B6.5XFAD x BXD44)F1-ADtg f 60.45 3.4578   2   2.445 0.0572 58.0, 62.89 1.32
(B6.5XFAD x BXD44)F1-ADtg m 35.525 6.4559   2   4.565 0.1817 30.96, 40.09 -0.37
(B6.5XFAD x BXD44)F1-Ntg f 20.445 28.914   2   20.445 1.4142 -1.25
(B6.5XFAD x BXD44)F1-Ntg m 48.22 0.0   1   0.0 0.0 48.22, 48.22 0.36
(B6.5XFAD x BXD51)F1-ADtg f 54.19 17.212   3 9.9373 0.3176 36.0, 70.22 0.92
(B6.5XFAD x BXD51)F1-Ntg f 50.81 45.433   3 26.231 0.8942 0.7
(B6.5XFAD x BXD55)F1-ADtg f 21.9 24.778   3 14.306 1.1314 4.9, 50.33 -1.16
(B6.5XFAD x BXD55)F1-Ntg f 16.395 13.5   4 6.75 0.8234 -1.51
(B6.5XFAD x BXD56)F1-ADtg f 56.0 13.52   2   9.56 0.2414 46.44, 65.56 1.04
(B6.5XFAD x BXD56)F1-Ntg f 72.05 6.6086   3 3.8155 0.0917 65.7, 78.89 2.07
(B6.5XFAD x BXD60)F1-ADtg f 60.22 37.081   2   26.22 0.6158 34.0, 86.44 1.31
(B6.5XFAD x BXD60)F1-ADtg m 39.265 3.9952   2   2.825 0.1017 36.44, 42.09 -0.15
(B6.5XFAD x BXD60)F1-Ntg f 16.59 12.756   2   9.02 0.7689 7.57, 25.61 -1.5
(B6.5XFAD x BXD61)F1-ADtg f 53.38 15.966   2   11.29 0.2991 42.09, 64.67 0.87
(B6.5XFAD x BXD61)F1-ADtg m 49.625 18.321   2   12.955 0.3692 36.67, 62.58 0.44
(B6.5XFAD x BXD61)F1-Ntg f 49.56 0.0   1   0.0 0.0 49.56, 49.56 0.62
(B6.5XFAD x BXD61)F1-Ntg m 32.175 39.223   2   27.735 1.2191 4.44, 59.91 -0.56
(B6.5XFAD x BXD62)F1-ADtg f 62.81 0.0   1   0.0 0.0 62.81, 62.81 1.48
(B6.5XFAD x BXD62)F1-ADtg m 57.02 22.677   2   16.035 0.3977 40.98, 73.05 0.87
(B6.5XFAD x BXD62)F1-Ntg f 49.22 34.959   2   24.72 0.7103 24.5, 73.94 0.6
(B6.5XFAD x BXD62)F1-Ntg m 56.89 0.0   1   0.0 0.0 56.89, 56.89 0.86
(B6.5XFAD x BXD65)F1-ADtg f 45.437 38.768   3 22.383 0.8532 1.56, 75.06 0.36
(B6.5XFAD x BXD65)F1-ADtg m 42.915 25.732   2   18.195 0.5996 24.72, 61.11 0.06
(B6.5XFAD x BXD65)F1-Ntg f 51.0 0.0   1   0.0 0.0 51.0, 51.0 0.72
(B6.5XFAD x BXD65)F1-Ntg m 44.688 34.064   4 17.032 0.7623 0.16
(B6.5XFAD x BXD66)F1-ADtg f 3.78 0.0   1   0.0 0.0 3.78, 3.78 -2.32
(B6.5XFAD x BXD66)F1-ADtg m 46.403 29.858   4 14.929 0.6435 1.78, 64.89 0.26
(B6.5XFAD x BXD66)F1-Ntg f 25.78 0.0   1   0.0 0.0 25.78, 25.78 -0.91
(B6.5XFAD x BXD66)F1-Ntg m 1.78 0.0   1   0.0 0.0 1.78, 1.78 -2.31
(B6.5XFAD x BXD68)F1-ADtg f 57.24 23.485   6 9.5879 0.4103 24.0, 80.85 1.12
(B6.5XFAD x BXD68)F1-ADtg m 23.56 0.0   1   0.0 0.0 23.56, 23.56 -1.05
(B6.5XFAD x BXD68)F1-Ntg f 32.037 25.167   9 8.3889 0.7856 6.44, 68.0 -0.5
(B6.5XFAD x BXD68)F1-Ntg m 59.0 1.7253   2   1.22 0.0292 57.78, 60.22 0.98
(B6.5XFAD x BXD69)F1-ADtg f 56.89 7.2266   2   5.11 0.127 51.78, 62.0 1.09
(B6.5XFAD x BXD69)F1-ADtg m 42.0 0.0   1   0.0 0.0 42.0, 42.0 0.01
(B6.5XFAD x BXD69)F1-Ntg f 38.08 0.0   1   0.0 0.0 38.08, 38.08 -0.12
(B6.5XFAD x BXD75)F1-ADtg f 43.968 12.316   4 6.1579 0.2801 30.0, 58.89 0.26
(B6.5XFAD x BXD75)F1-ADtg m 47.725 5.5791   2   3.945 0.1169 43.78, 51.67 0.33
(B6.5XFAD x BXD75)F1-Ntg f 30.043 17.653   3 10.192 0.5876 11.14, 46.1 -0.63
(B6.5XFAD x BXD75)F1-Ntg m 57.68 0.0   1   0.0 0.0 57.68, 57.68 0.91
(B6.5XFAD x BXD77)F1-ADtg f 49.375 14.078   2   9.955 0.2851 39.42, 59.33 0.61
(B6.5XFAD x BXD77)F1-ADtg m 8.91 0.0   1   0.0 0.0 8.91, 8.91 -1.9
(B6.5XFAD x BXD77)F1-Ntg f 8.11 3.9315   2   2.78 0.4848 5.33, 10.89 -2.05
(B6.5XFAD x BXD77)F1-Ntg m 13.34 5.6427   2   3.99 0.423 9.35, 17.33 -1.64
(B6.5XFAD x BXD81)F1-ADtg f 16.548 12.541   6 5.1199 0.7578 1.56, 30.73 -1.5
(B6.5XFAD x BXD81)F1-Ntg f 40.89 8.5164   3 4.9169 0.2083 35.11, 50.67 0.06
(B6.5XFAD x BXD87)F1-ADtg f 13.78 14.131   3 8.1588 1.0255 0.89, 28.89 -1.68
(B6.5XFAD x BXD87)F1-ADtg m 39.87 0.0   1   0.0 0.0 39.87, 39.87 -0.12
(B6.5XFAD x BXD87)F1-Ntg f 43.783 28.722   3 16.583 0.656 10.69, 62.22 0.25
(B6.5XFAD x BXD87)F1-Ntg m 62.51 27.773   3 16.035 0.4443 42.44, 94.21 1.18
(B6.5XFAD x BXD99)F1-ADtg f 58.84 16.78   3 9.688 0.2852 40.09, 72.44 1.22
(B6.5XFAD x D2)F1-ADtg f 41.082 22.077   16 5.5192 0.5374 4.68, 73.78 0.08
(B6.5XFAD x D2)F1-ADtg m 43.915 17.474   13 4.8463 0.3979 8.46, 61.56 0.12
(B6.5XFAD x D2)F1-Ntg f 32.048 22.165   11 6.6831 0.6916 3.78, 60.13 -0.5
(B6.5XFAD x D2)F1-Ntg m 39.181 21.368   8 7.5548 0.5454 3.79, 65.56 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 39.27 15.4156 69.8737 8.6663
(B6.5XFAD x B6)F1-ADtg m 76.9029 8.24 93.2612 60.5445
(B6.5XFAD x B6)F1-Ntg f 44.785 8.9002 62.4541 27.1159
(B6.5XFAD x B6)F1-Ntg m 58.075 10.9004 79.7151 36.4349
(B6.5XFAD x BXD100)F1-ADtg f 40.8975 10.9004 62.5376 19.2574
(B6.5XFAD x BXD100)F1-ADtg m 19.67 15.4156 50.2737 -10.9337
(B6.5XFAD x BXD32)F1-ADtg f 46.2225 10.9004 67.8626 24.5824
(B6.5XFAD x BXD32)F1-ADtg m 30.065 15.4156 60.6687 -0.5387
(B6.5XFAD x BXD44)F1-ADtg f 60.445 15.4156 91.0487 29.8413
(B6.5XFAD x BXD44)F1-ADtg m 35.525 15.4156 66.1287 4.9213
(B6.5XFAD x BXD60)F1-ADtg f 60.22 15.4156 90.8237 29.6163
(B6.5XFAD x BXD60)F1-ADtg m 39.265 15.4156 69.8687 8.6613
(B6.5XFAD x BXD61)F1-ADtg f 53.38 15.4156 83.9837 22.7763
(B6.5XFAD x BXD61)F1-ADtg m 49.625 15.4156 80.2287 19.0213
(B6.5XFAD x BXD65)F1-ADtg f 45.4367 12.5867 70.4245 20.4488
(B6.5XFAD x BXD65)F1-ADtg m 42.915 15.4156 73.5187 12.3113
(B6.5XFAD x BXD68)F1-Ntg f 32.0367 7.267 46.4634 17.6099
(B6.5XFAD x BXD68)F1-Ntg m 59.0 15.4156 89.6037 28.3963
(B6.5XFAD x BXD75)F1-ADtg f 43.9675 10.9004 65.6076 22.3274
(B6.5XFAD x BXD75)F1-ADtg m 47.725 15.4156 78.3287 17.1213
(B6.5XFAD x BXD77)F1-Ntg f 8.11 15.4156 38.7137 -22.4937
(B6.5XFAD x BXD77)F1-Ntg m 13.34 15.4156 43.9437 -17.2637
(B6.5XFAD x BXD87)F1-Ntg f 43.7833 12.5867 68.7712 18.7955
(B6.5XFAD x BXD87)F1-Ntg m 62.5133 12.5867 87.5012 37.5255
(B6.5XFAD x D2)F1-ADtg f 41.0819 5.4502 51.9019 30.2618
(B6.5XFAD x D2)F1-ADtg m 43.9146 6.0465 55.9184 31.9108
(B6.5XFAD x D2)F1-Ntg f 32.0482 6.5732 45.0977 18.9987
(B6.5XFAD x D2)F1-Ntg m 39.1813 7.7078 54.4831 23.8794


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 58.0864 8.7398 75.4371 40.7357
(B6.5XFAD x B6)F1-Ntg both 51.43 7.0362 65.3986 37.4614
(B6.5XFAD x BXD100)F1-ADtg both 30.2838 9.4401 49.0246 11.5429
(B6.5XFAD x BXD32)F1-ADtg both 38.1438 9.4401 56.8846 19.4029
(B6.5XFAD x BXD44)F1-ADtg both 47.985 10.9004 69.6251 26.3449
(B6.5XFAD x BXD60)F1-ADtg both 49.7425 10.9004 71.3826 28.1024
(B6.5XFAD x BXD61)F1-ADtg both 51.5025 10.9004 73.1426 29.8624
(B6.5XFAD x BXD65)F1-ADtg both 44.1758 9.9507 63.9305 24.4212
(B6.5XFAD x BXD68)F1-Ntg both 45.5183 8.5213 62.4352 28.6015
(B6.5XFAD x BXD75)F1-ADtg both 45.8463 9.4401 64.5871 27.1054
(B6.5XFAD x BXD77)F1-Ntg both 10.725 10.9004 32.3651 -10.9151
(B6.5XFAD x BXD87)F1-Ntg both 53.1483 8.9002 70.8174 35.4793
(B6.5XFAD x D2)F1-ADtg both 42.4982 4.0702 50.5785 34.418
(B6.5XFAD x D2)F1-Ntg both 35.6147 5.065 45.67 25.5594




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA