Project measure / variable:   Neuner1   cfa_change_14mo

ID, description, units MPD:65973   cfa_change_14mo   change in percentage of time spent freezing from 1st post-shock to 4th post-shock (slope), day 1 contextual fear acquisition    14 mo  
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 23-57wks
Procedure fear conditioning test
Ontology mappings

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  STRAIN COMPARISON PLOT
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Neuner1 - change in percentage of time spent freezing from 1st post-shock to 4th post-shock (slope), day 1 contextual fear acquisition 14 mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means6.2246   None 5.2303   None
Median of the strain means5.9068   None 6.065   None
SD of the strain means± 5.5544 ± 5.2724
Coefficient of variation (CV)0.8923 1.008
Min–max range of strain means-3.7323   –   15.54   None -5.801   –   15.669   None
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 161.8194 161.8194 3.2124 0.0744
strain 25 6859.9493 274.398 5.4473 < 0.0001
sex:strain 25 1564.0107 62.5604 1.2419 0.2049
Residuals 222 11182.9518 50.3737


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 1.553 8.3614   27 1.6091 5.3839 -18.852, 14.754 -0.7
(B6.5XFAD x B6)F1-Ntg f 6.8492 4.8939   9 1.6313 0.7145 0.414, 14.198 0.11
(B6.5XFAD x B6)F1-Ntg m 13.399 5.3621   11 1.6167 0.4002 5.734, 23.959 1.55
(B6.5XFAD x BXD100)F1-ADtg f -0.959 3.6218   2   2.561 -3.7766 -3.52, 1.602 -1.29
(B6.5XFAD x BXD100)F1-ADtg m -4.7681 8.073   7 3.0513 -1.6931 -13.998, 4.403 -1.9
(B6.5XFAD x BXD100)F1-Ntg f 7.5765 6.8476   4 3.4238 0.9038 2.066, 17.509 0.24
(B6.5XFAD x BXD100)F1-Ntg m 1.5583 7.1446   6 2.9168 4.5848 -9.142, 12.096 -0.7
(B6.5XFAD x BXD14)F1-ADtg f -1.6635 4.4357   2   3.1365 -2.6665 -4.8, 1.473 -1.42
(B6.5XFAD x BXD14)F1-Ntg f 7.867 8.0143   2   5.667 1.0187 2.2, 13.534 0.3
(B6.5XFAD x BXD16)F1-ADtg f 3.6107 5.7976   4 2.8988 1.6057 -1.064, 11.866 -0.47
(B6.5XFAD x BXD22)F1-ADtg f 15.407 1.5189   2   1.074 0.0986 14.333, 16.481 1.65
(B6.5XFAD x BXD22)F1-Ntg f -2.334 12.727   2   8.999 -5.4527 -11.333, 6.665 -1.54
(B6.5XFAD x BXD32)F1-ADtg f -3.268 0.09475   2   0.067 -0.029 -3.335, -3.201 -1.71
(B6.5XFAD x BXD32)F1-ADtg m 3.5383 2.4018   3 1.3867 0.6788 0.935, 5.668 -0.32
(B6.5XFAD x BXD32)F1-Ntg f 7.5107 4.8747   3 2.8144 0.649 2.001, 11.263 0.23
(B6.5XFAD x BXD32)F1-Ntg m 8.5655 6.4594   2   4.5675 0.7541 3.998, 13.133 0.63
(B6.5XFAD x BXD42)F1-ADtg f 1.7685 0.80115   2   0.5665 0.453 1.202, 2.335 -0.8
(B6.5XFAD x BXD42)F1-Ntg f 3.399 0.0   1   0.0 0.0 3.399, 3.399 -0.51
(B6.5XFAD x BXD44)F1-ADtg f 1.4016 6.7645   13 1.8761 4.8262 -8.4, 10.842 -0.87
(B6.5XFAD x BXD44)F1-ADtg m 1.5742 7.1001   8 2.5103 4.5101 -11.979, 10.923 -0.69
(B6.5XFAD x BXD44)F1-Ntg f 15.265 0.0   1   0.0 0.0 15.265, 15.265 1.63
(B6.5XFAD x BXD44)F1-Ntg m 7.455 4.7142   3 2.7217 0.6323 2.161, 11.199 0.42
(B6.5XFAD x BXD51)F1-ADtg f 0.45667 13.924   6 5.6843 30.4899 -11.906, 27.868 -1.04
(B6.5XFAD x BXD51)F1-Ntg f 12.385 9.7443   4 4.8721 0.7868 1.11
(B6.5XFAD x BXD55)F1-ADtg f 0.09975 0.38271   4 0.19135 3.8367 -0.4, 0.4 -1.1
(B6.5XFAD x BXD55)F1-Ntg f 2.7475 4.167   2   2.9465 1.5166 -0.199, 5.694 -0.63
(B6.5XFAD x BXD56)F1-ADtg m -5.801 0.0   1   0.0 0.0 -5.801, -5.801 -2.09
(B6.5XFAD x BXD56)F1-Ntg f 10.467 7.3532   2   5.1995 0.7025 5.268, 15.667 0.76
(B6.5XFAD x BXD56)F1-Ntg m 4.733 0.0   1   0.0 0.0 4.733, 4.733 -0.09
(B6.5XFAD x BXD60)F1-ADtg f 6.407 10.415   4 5.2077 1.6256 -4.887, 15.558 0.03
(B6.5XFAD x BXD60)F1-ADtg m 6.208 8.6359   5 3.8621 1.3911 -8.932, 11.998 0.19
(B6.5XFAD x BXD60)F1-Ntg f 13.325 3.2239   3 1.8613 0.2419 10.269, 16.694 1.28
(B6.5XFAD x BXD61)F1-ADtg f 5.0137 9.6897   7 3.6624 1.9326 -12.867, 17.364 -0.22
(B6.5XFAD x BXD61)F1-ADtg m 8.7687 4.6512   3 2.6854 0.5304 5.842, 14.132 0.67
(B6.5XFAD x BXD61)F1-Ntg f 10.696 14.723   5 6.5841 1.3764 -7.284, 25.866 0.81
(B6.5XFAD x BXD61)F1-Ntg m 10.374 5.6471   6 2.3054 0.5443 -0.066, 15.509 0.98
(B6.5XFAD x BXD62)F1-ADtg f 1.3583 2.9477   3 1.7019 2.1701 -1.0, 4.663 -0.88
(B6.5XFAD x BXD62)F1-ADtg m 6.451 4.0461   2   2.861 0.6272 3.59, 9.312 0.23
(B6.5XFAD x BXD62)F1-Ntg f 13.131 6.3798   3 3.6834 0.4858 6.335, 18.991 1.24
(B6.5XFAD x BXD62)F1-Ntg m 11.855 5.1587   3 2.9784 0.4352 5.899, 14.932 1.26
(B6.5XFAD x BXD65)F1-ADtg f 11.751 8.4852   6 3.4641 0.7221 0.8, 23.438 0.99
(B6.5XFAD x BXD65)F1-ADtg m 6.065 4.9964   2   3.533 0.8238 2.532, 9.598 0.16
(B6.5XFAD x BXD65)F1-Ntg f 15.54 6.479   8 2.2907 0.4169 7.199, 24.176 1.68
(B6.5XFAD x BXD65)F1-Ntg m 5.134 7.7315   2   5.467 1.5059 -0.333, 10.601 -0.02
(B6.5XFAD x BXD66)F1-ADtg f -2.619 4.6758   3 2.6996 -1.7853 -7.999, 0.464 -1.59
(B6.5XFAD x BXD66)F1-ADtg m 6.1022 7.1343   5 3.1906 1.1691 -2.666, 15.836 0.17
(B6.5XFAD x BXD66)F1-Ntg f 12.0 0.0   1   0.0 0.0 12.0, 12.0 1.04
(B6.5XFAD x BXD66)F1-Ntg m 4.3777 6.583   3 3.8007 1.5038 -1.134, 11.667 -0.16
(B6.5XFAD x BXD68)F1-ADtg f 7.1003 6.7442   3 3.8938 0.9498 -0.6, 11.957 0.16
(B6.5XFAD x BXD68)F1-ADtg m 3.9397 3.9722   7 1.5013 1.0082 -1.866, 9.866 -0.24
(B6.5XFAD x BXD68)F1-Ntg f 10.454 7.1674   10 2.2665 0.6856 -1.733, 19.867 0.76
(B6.5XFAD x BXD68)F1-Ntg m 4.0665 5.1852   2   3.6665 1.2751 0.4, 7.733 -0.22
(B6.5XFAD x BXD69)F1-ADtg f 4.2863 4.3442   6 1.7735 1.0135 -0.787, 9.794 -0.35
(B6.5XFAD x BXD69)F1-ADtg m 1.3506 5.0403   5 2.2541 3.7319 -5.601, 6.933 -0.74
(B6.5XFAD x BXD69)F1-Ntg f 6.0335 3.1518   4 1.5759 0.5224 3.816, 10.533 -0.03
(B6.5XFAD x BXD69)F1-Ntg m 9.6532 6.1361   6 2.505 0.6357 -1.409, 14.674 0.84
(B6.5XFAD x BXD70)F1-ADtg f 5.13 0.0   1   0.0 0.0 5.13, 5.13 -0.2
(B6.5XFAD x BXD70)F1-ADtg m -0.613 8.9719   3 5.1799 -14.636 -9.992, 7.887 -1.11
(B6.5XFAD x BXD70)F1-Ntg f 13.8 9.733   3 5.6194 0.7053 5.4, 24.466 1.36
(B6.5XFAD x BXD70)F1-Ntg m 11.236 0.6265   2   0.443 0.0558 10.793, 11.679 1.14
(B6.5XFAD x BXD75)F1-ADtg f -0.17825 4.1753   4 2.0877 -23.424 -5.464, 4.751 -1.15
(B6.5XFAD x BXD75)F1-ADtg m -1.8145 5.6442   4 2.8221 -3.1106 -8.999, 3.468 -1.34
(B6.5XFAD x BXD75)F1-Ntg f 9.5555 4.7598   6 1.9432 0.4981 2.999, 14.333 0.6
(B6.5XFAD x BXD75)F1-Ntg m 15.669 0.0   1   0.0 0.0 15.669, 15.669 1.98
(B6.5XFAD x BXD77)F1-ADtg f -3.7323 2.3695   3 1.368 -0.6349 -6.376, -1.8 -1.79
(B6.5XFAD x BXD77)F1-ADtg m -0.8 11.3   3 6.5242 -14.1253 -12.867, 9.533 -1.14
(B6.5XFAD x BXD77)F1-Ntg f 10.875 5.9051   10 1.8674 0.543 4.933, 19.864 0.84
(B6.5XFAD x BXD77)F1-Ntg m 2.5172 4.7461   6 1.9376 1.8855 -4.599, 9.234 -0.51
(B6.5XFAD x BXD81)F1-ADtg f 3.8065 3.6131   6 1.475 0.9492 -0.934, 8.399 -0.44
(B6.5XFAD x BXD81)F1-Ntg f 10.836 4.2836   5 1.9157 0.3953 5.801, 16.444 0.83
(B6.5XFAD x BXD87)F1-ADtg f 4.0244 7.2026   10 2.2777 1.7897 -8.432, 17.402 -0.4
(B6.5XFAD x BXD87)F1-ADtg m 11.734 10.413   4 5.2067 0.8874 2.206, 25.001 1.23
(B6.5XFAD x BXD87)F1-Ntg f 5.5743 9.4755   3 5.4707 1.6998 -4.333, 14.549 -0.12
(B6.5XFAD x BXD87)F1-Ntg m 7.833 0.0   1   0.0 0.0 7.833, 7.833 0.49
(B6.5XFAD x BXD89)F1-ADtg m 8.534 0.0   1   0.0 0.0 8.534, 8.534 0.63
(B6.5XFAD x BXD89)F1-Ntg f 5.78 12.152   2   8.593 2.1025 -2.813, 14.373 -0.08
(B6.5XFAD x BXD89)F1-Ntg m 7.533 0.84853   2   0.6 0.1126 6.933, 8.133 0.44
(B6.5XFAD x BXD99)F1-ADtg f 4.334 0.0   1   0.0 0.0 4.334, 4.334 -0.34
(B6.5XFAD x BXD99)F1-Ntg f 11.858 0.0   1   0.0 0.0 11.858, 11.858 1.01
(B6.5XFAD x D2)F1-ADtg f -0.32906 6.795   17 1.648 -20.6498 -10.2, 11.605 -1.18
(B6.5XFAD x D2)F1-ADtg m -5.1981 9.9139   8 3.5051 -1.9072 -21.56, 10.336 -1.98
(B6.5XFAD x D2)F1-Ntg f 14.382 8.3292   12 2.4044 0.5791 0.999, 27.267 1.47
(B6.5XFAD x D2)F1-Ntg m 10.277 8.9385   4 4.4692 0.8697 0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 6.8492 2.3658 11.5115 2.1869
(B6.5XFAD x B6)F1-Ntg m 13.399 2.14 17.6162 9.1818
(B6.5XFAD x BXD100)F1-ADtg f -0.959 5.0186 8.9313 -10.8493
(B6.5XFAD x BXD100)F1-ADtg m -4.7681 2.6826 0.5184 -10.0547
(B6.5XFAD x BXD100)F1-Ntg f 7.5765 3.5487 14.57 0.583
(B6.5XFAD x BXD100)F1-Ntg m 1.5583 2.8975 7.2685 -4.1518
(B6.5XFAD x BXD32)F1-ADtg f -3.268 5.0186 6.6223 -13.1583
(B6.5XFAD x BXD32)F1-ADtg m 3.5383 4.0977 11.6137 -4.5371
(B6.5XFAD x BXD32)F1-Ntg f 7.5107 4.0977 15.5861 -0.5647
(B6.5XFAD x BXD32)F1-Ntg m 8.5655 5.0186 18.4558 -1.3248
(B6.5XFAD x BXD44)F1-ADtg f 1.4016 1.9685 5.2809 -2.4777
(B6.5XFAD x BXD44)F1-ADtg m 1.5742 2.5093 6.5194 -3.3709
(B6.5XFAD x BXD60)F1-ADtg f 6.407 3.5487 13.4005 -0.5865
(B6.5XFAD x BXD60)F1-ADtg m 6.208 3.1741 12.4632 -0.0472
(B6.5XFAD x BXD61)F1-ADtg f 5.0137 2.6826 10.3003 -0.2729
(B6.5XFAD x BXD61)F1-ADtg m 8.7687 4.0977 16.8441 0.6933
(B6.5XFAD x BXD61)F1-Ntg f 10.6964 3.1741 16.9516 4.4412
(B6.5XFAD x BXD61)F1-Ntg m 10.3743 2.8975 16.0845 4.6642
(B6.5XFAD x BXD62)F1-ADtg f 1.3583 4.0977 9.4337 -6.7171
(B6.5XFAD x BXD62)F1-ADtg m 6.451 5.0186 16.3413 -3.4393
(B6.5XFAD x BXD62)F1-Ntg f 13.1313 4.0977 21.2067 5.0559
(B6.5XFAD x BXD62)F1-Ntg m 11.8547 4.0977 19.9301 3.7793
(B6.5XFAD x BXD65)F1-ADtg f 11.7508 2.8975 17.461 6.0407
(B6.5XFAD x BXD65)F1-ADtg m 6.065 5.0186 15.9553 -3.8253
(B6.5XFAD x BXD65)F1-Ntg f 15.5401 2.5093 20.4853 10.595
(B6.5XFAD x BXD65)F1-Ntg m 5.134 5.0186 15.0243 -4.7563
(B6.5XFAD x BXD66)F1-ADtg f -2.619 4.0977 5.4564 -10.6944
(B6.5XFAD x BXD66)F1-ADtg m 6.1022 3.1741 12.3574 -0.153
(B6.5XFAD x BXD68)F1-ADtg f 7.1003 4.0977 15.1757 -0.9751
(B6.5XFAD x BXD68)F1-ADtg m 3.9397 2.6826 9.2263 -1.3469
(B6.5XFAD x BXD68)F1-Ntg f 10.4539 2.2444 14.877 6.0308
(B6.5XFAD x BXD68)F1-Ntg m 4.0665 5.0186 13.9568 -5.8238
(B6.5XFAD x BXD69)F1-ADtg f 4.2863 2.8975 9.9965 -1.4238
(B6.5XFAD x BXD69)F1-ADtg m 1.3506 3.1741 7.6058 -4.9046
(B6.5XFAD x BXD69)F1-Ntg f 6.0335 3.5487 13.027 -0.96
(B6.5XFAD x BXD69)F1-Ntg m 9.6532 2.8975 15.3633 3.943
(B6.5XFAD x BXD70)F1-Ntg f 13.7997 4.0977 21.8751 5.7243
(B6.5XFAD x BXD70)F1-Ntg m 11.236 5.0186 21.1263 1.3457
(B6.5XFAD x BXD75)F1-ADtg f -0.1783 3.5487 6.8152 -7.1717
(B6.5XFAD x BXD75)F1-ADtg m -1.8145 3.5487 5.179 -8.808
(B6.5XFAD x BXD77)F1-ADtg f -3.7323 4.0977 4.3431 -11.8077
(B6.5XFAD x BXD77)F1-ADtg m -0.8 4.0977 7.2754 -8.8754
(B6.5XFAD x BXD77)F1-Ntg f 10.8748 2.2444 15.2979 6.4517
(B6.5XFAD x BXD77)F1-Ntg m 2.5172 2.8975 8.2273 -3.193
(B6.5XFAD x BXD87)F1-ADtg f 4.0244 2.2444 8.4475 -0.3987
(B6.5XFAD x BXD87)F1-ADtg m 11.7342 3.5487 18.7277 4.7408
(B6.5XFAD x BXD89)F1-Ntg f 5.78 5.0186 15.6703 -4.1103
(B6.5XFAD x BXD89)F1-Ntg m 7.533 5.0186 17.4233 -2.3573
(B6.5XFAD x D2)F1-ADtg f -0.3291 1.7214 3.0633 -3.7214
(B6.5XFAD x D2)F1-ADtg m -5.1981 2.5093 -0.253 -10.1433
(B6.5XFAD x D2)F1-Ntg f 14.3819 2.0489 18.4196 10.3442
(B6.5XFAD x D2)F1-Ntg m 10.2775 3.5487 17.271 3.284


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 10.1241 1.595 13.2675 6.9808
(B6.5XFAD x BXD100)F1-ADtg both -2.8636 2.8453 2.7437 -8.4708
(B6.5XFAD x BXD100)F1-Ntg both 4.5674 2.2907 9.0817 0.0531
(B6.5XFAD x BXD32)F1-ADtg both 0.1352 3.2395 6.5193 -6.249
(B6.5XFAD x BXD32)F1-Ntg both 8.0381 3.2395 14.4222 1.6539
(B6.5XFAD x BXD44)F1-ADtg both 1.4879 1.5946 4.6305 -1.6547
(B6.5XFAD x BXD60)F1-ADtg both 6.3075 2.3806 10.9989 1.6161
(B6.5XFAD x BXD61)F1-ADtg both 6.8912 2.4488 11.7172 2.0652
(B6.5XFAD x BXD61)F1-Ntg both 10.5354 2.1489 14.7701 6.3006
(B6.5XFAD x BXD62)F1-ADtg both 3.9047 3.2395 10.2888 -2.4795
(B6.5XFAD x BXD62)F1-Ntg both 12.493 2.8975 18.2032 6.7828
(B6.5XFAD x BXD65)F1-ADtg both 8.9079 2.8975 14.6181 3.1978
(B6.5XFAD x BXD65)F1-Ntg both 10.3371 2.8055 15.8659 4.8082
(B6.5XFAD x BXD66)F1-ADtg both 1.7416 2.5916 6.8489 -3.3657
(B6.5XFAD x BXD68)F1-ADtg both 5.52 2.4488 10.346 0.6941
(B6.5XFAD x BXD68)F1-Ntg both 7.2602 2.7488 12.6773 1.8431
(B6.5XFAD x BXD69)F1-ADtg both 2.8185 2.1489 7.0532 -1.4163
(B6.5XFAD x BXD69)F1-Ntg both 7.8433 2.2907 12.3576 3.3291
(B6.5XFAD x BXD70)F1-Ntg both 12.5178 3.2395 18.902 6.1337
(B6.5XFAD x BXD75)F1-ADtg both -0.9964 2.5093 3.9488 -5.9415
(B6.5XFAD x BXD77)F1-ADtg both -2.2662 2.8975 3.444 -7.9763
(B6.5XFAD x BXD77)F1-Ntg both 6.696 1.8326 10.3074 3.0846
(B6.5XFAD x BXD87)F1-ADtg both 7.8793 2.0995 12.0167 3.7419
(B6.5XFAD x BXD89)F1-Ntg both 6.6565 3.5487 13.65 -0.337
(B6.5XFAD x D2)F1-ADtg both -2.7636 1.5215 0.2348 -5.762
(B6.5XFAD x D2)F1-Ntg both 12.3297 2.0489 16.3674 8.292




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA