Phenotype measure:   Neuner1   cfc_14mo_shock3

ID, description, units MPD:65970   cfc_14mo_shock3   percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning   [%]  3rd shock
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning 3rd shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means29.448   % 36.526   %
Median of the strain means29.907   % 35.876   %
SD of the strain means± 17.067 ± 12.662
Coefficient of variation (CV)0.5796 0.3467
Min–max range of strain means0.0   –   70.67   % 12.391   –   68.0   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
Residuals 222 85515.3212 385.2041
sex 1 3.8791 3.8791 0.0101 0.9202
strain 25 24192.1062 967.6842 2.5121 0.0002
sex:strain 25 13590.5217 543.6209 1.4113 0.0996


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 37.462 18.085   27 3.4804 0.4827 8.67, 76.0 0.07
(B6.5XFAD x B6)F1-Ntg f 35.416 19.676   9 6.5586 0.5556 13.33, 70.47 0.35
(B6.5XFAD x B6)F1-Ntg m 41.955 17.035   11 5.1361 0.406 12.08, 69.8 0.43
(B6.5XFAD x BXD100)F1-ADtg f 16.335 11.787   2   8.335 0.7216 8.0, 24.67 -0.77
(B6.5XFAD x BXD100)F1-ADtg m 12.391 12.965   7 4.9003 1.0463 2.67, 38.0 -1.91
(B6.5XFAD x BXD100)F1-Ntg f 27.435 26.289   4 13.144 0.9582 4.0, 60.4 -0.12
(B6.5XFAD x BXD100)F1-Ntg m 21.942 20.452   6 8.3496 0.9321 3.33, 48.32 -1.15
(B6.5XFAD x BXD14)F1-ADtg f 3.0 4.2426   2   3.0 1.4142 -1.55
(B6.5XFAD x BXD14)F1-Ntg f 25.0 35.355   2   25.0 1.4142 -0.26
(B6.5XFAD x BXD16)F1-ADtg f 22.0 21.068   4 10.534 0.9576 -0.44
(B6.5XFAD x BXD22)F1-ADtg f 37.665 6.1306   2   4.335 0.1628 33.33, 42.0 0.48
(B6.5XFAD x BXD22)F1-Ntg f 46.67 50.91   2   36.0 1.0909 10.67, 82.67 1.01
(B6.5XFAD x BXD32)F1-ADtg f 30.665 43.367   2   30.665 1.4142 0.07
(B6.5XFAD x BXD32)F1-ADtg m 30.0 2.406   3 1.3891 0.0802 28.0, 32.67 -0.52
(B6.5XFAD x BXD32)F1-Ntg f 6.89 8.2278   3 4.7503 1.1942 -1.32
(B6.5XFAD x BXD32)F1-Ntg m 32.665 0.94045   2   0.665 0.0288 32.0, 33.33 -0.3
(B6.5XFAD x BXD42)F1-ADtg f 26.335 22.154   2   15.665 0.8412 10.67, 42.0 -0.18
(B6.5XFAD x BXD42)F1-Ntg f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.37
(B6.5XFAD x BXD44)F1-ADtg f 36.052 24.422   13 6.7734 0.6774 5.33, 82.67 0.39
(B6.5XFAD x BXD44)F1-ADtg m 24.859 13.763   8 4.8661 0.5537 3.33, 45.33 -0.92
(B6.5XFAD x BXD44)F1-Ntg f 69.33 0.0   1   0.0 0.0 69.33, 69.33 2.34
(B6.5XFAD x BXD44)F1-Ntg m 33.347 29.521   3 17.044 0.8853 6.04, 64.67 -0.25
(B6.5XFAD x BXD51)F1-ADtg f 53.28 15.009   6 6.1273 0.2817 28.0, 74.0 1.4
(B6.5XFAD x BXD51)F1-Ntg f 29.335 30.777   4 15.389 1.0492 -0.01
(B6.5XFAD x BXD55)F1-ADtg f 3.8325 5.3422   4 2.6711 1.3939 -1.5
(B6.5XFAD x BXD55)F1-Ntg f 7.335 10.373   2   7.335 1.4142 -1.3
(B6.5XFAD x BXD56)F1-ADtg m 68.0 0.0   1   0.0 0.0 68.0, 68.0 2.49
(B6.5XFAD x BXD56)F1-Ntg f 27.85 39.386   2   27.85 1.4142 -0.09
(B6.5XFAD x BXD56)F1-Ntg m 41.33 0.0   1   0.0 0.0 41.33, 41.33 0.38
(B6.5XFAD x BXD60)F1-ADtg f 27.332 24.98   4 12.49 0.9139 -0.12
(B6.5XFAD x BXD60)F1-ADtg m 37.302 19.067   5 8.5269 0.5111 16.0, 66.67 0.06
(B6.5XFAD x BXD60)F1-Ntg f 30.74 20.149   3 11.633 0.6555 9.33, 49.33 0.08
(B6.5XFAD x BXD61)F1-ADtg f 29.419 14.165   7 5.3539 0.4815 3.36, 44.3 0.0
(B6.5XFAD x BXD61)F1-ADtg m 56.56 4.132   3 2.3856 0.0731 54.0, 61.33 1.58
(B6.5XFAD x BXD61)F1-Ntg f 60.93 18.1   5 8.0944 0.297 28.67, 71.33 1.84
(B6.5XFAD x BXD61)F1-Ntg m 37.523 28.994   6 11.837 0.7727 0.08
(B6.5XFAD x BXD62)F1-ADtg f 12.523 8.5595   3 4.9418 0.6835 2.67, 18.12 -0.99
(B6.5XFAD x BXD62)F1-ADtg m 32.665 30.172   2   21.335 0.9237 11.33, 54.0 -0.3
(B6.5XFAD x BXD62)F1-Ntg f 49.43 7.5769   3 4.3745 0.1533 43.62, 58.0 1.17
(B6.5XFAD x BXD62)F1-Ntg m 54.0 23.705   3 13.686 0.439 27.33, 72.67 1.38
(B6.5XFAD x BXD65)F1-ADtg f 46.505 20.522   6 8.378 0.4413 8.0, 69.33 1.0
(B6.5XFAD x BXD65)F1-ADtg m 58.0 11.314   2   8.0 0.1951 50.0, 66.0 1.7
(B6.5XFAD x BXD65)F1-Ntg f 43.584 22.122   8 7.8212 0.5076 16.67, 78.67 0.83
(B6.5XFAD x BXD65)F1-Ntg m 60.0 3.776   2   2.67 0.0629 57.33, 62.67 1.85
(B6.5XFAD x BXD66)F1-ADtg f 35.08 33.754   3 19.488 0.9622 12.08, 73.83 0.33
(B6.5XFAD x BXD66)F1-ADtg m 43.004 12.407   5 5.5486 0.2885 22.67, 52.35 0.51
(B6.5XFAD x BXD66)F1-Ntg f 40.0 0.0   1   0.0 0.0 40.0, 40.0 0.62
(B6.5XFAD x BXD66)F1-Ntg m 32.0 32.0   3 18.475 1.0 -0.36
(B6.5XFAD x BXD68)F1-ADtg f 17.843 15.698   3 9.0634 0.8798 -0.68
(B6.5XFAD x BXD68)F1-ADtg m 35.876 14.119   7 5.3365 0.3936 18.0, 64.0 -0.05
(B6.5XFAD x BXD68)F1-Ntg f 40.768 29.773   10 9.4149 0.7303 0.66
(B6.5XFAD x BXD68)F1-Ntg m 31.0 38.184   2   27.0 1.2317 4.0, 58.0 -0.44
(B6.5XFAD x BXD69)F1-ADtg f 30.038 18.906   6 7.7185 0.6294 8.0, 51.33 0.03
(B6.5XFAD x BXD69)F1-ADtg m 25.202 18.272   5 8.1717 0.725 -0.89
(B6.5XFAD x BXD69)F1-Ntg f 29.775 16.875   4 8.4373 0.5667 17.45, 54.67 0.02
(B6.5XFAD x BXD69)F1-Ntg m 27.593 21.359   6 8.7196 0.774 8.67, 66.0 -0.71
(B6.5XFAD x BXD70)F1-ADtg f 0.0 0.0   1   0.0 None -1.73
(B6.5XFAD x BXD70)F1-ADtg m 19.873 10.186   3 5.8807 0.5125 12.75, 31.54 -1.32
(B6.5XFAD x BXD70)F1-Ntg f 48.0 7.6869   3 4.4381 0.1601 40.67, 56.0 1.09
(B6.5XFAD x BXD70)F1-Ntg m 19.375 9.3692   2   6.625 0.4836 12.75, 26.0 -1.35
(B6.5XFAD x BXD75)F1-ADtg f 9.335 10.902   4 5.4511 1.1679 -1.18
(B6.5XFAD x BXD75)F1-ADtg m 38.523 21.811   4 10.905 0.5662 13.42, 62.67 0.16
(B6.5XFAD x BXD75)F1-Ntg f 31.002 18.129   6 7.401 0.5848 8.0, 52.0 0.09
(B6.5XFAD x BXD75)F1-Ntg m 50.67 0.0   1   0.0 0.0 50.67, 50.67 1.12
(B6.5XFAD x BXD77)F1-ADtg f 2.2367 3.874   3 2.2367 1.7321 -1.59
(B6.5XFAD x BXD77)F1-ADtg m 36.0 17.333   3 10.007 0.4815 25.33, 56.0 -0.04
(B6.5XFAD x BXD77)F1-Ntg f 31.91 15.894   10 5.0262 0.4981 0.14
(B6.5XFAD x BXD77)F1-Ntg m 18.902 8.6445   6 3.5291 0.4573 10.74, 32.0 -1.39
(B6.5XFAD x BXD81)F1-ADtg f 12.665 11.956   6 4.8809 0.944 -0.98
(B6.5XFAD x BXD81)F1-Ntg f 19.466 10.06   5 4.4988 0.5168 5.33, 29.33 -0.58
(B6.5XFAD x BXD87)F1-ADtg f 47.084 16.241   10 5.136 0.3449 8.67, 63.76 1.03
(B6.5XFAD x BXD87)F1-ADtg m 28.11 24.811   4 12.406 0.8826 4.03, 50.34 -0.66
(B6.5XFAD x BXD87)F1-Ntg f 32.21 29.881   3 17.252 0.9277 2.67, 62.42 0.16
(B6.5XFAD x BXD87)F1-Ntg m 49.66 0.0   1   0.0 0.0 49.66, 49.66 1.04
(B6.5XFAD x BXD89)F1-ADtg m 35.33 0.0   1   0.0 0.0 35.33, 35.33 -0.09
(B6.5XFAD x BXD89)F1-Ntg f 32.0 45.255   2   32.0 1.4142 0.15
(B6.5XFAD x BXD89)F1-Ntg m 37.0 6.1235   2   4.33 0.1655 32.67, 41.33 0.04
(B6.5XFAD x BXD99)F1-ADtg f 70.67 0.0   1   0.0 0.0 70.67, 70.67 2.42
(B6.5XFAD x BXD99)F1-Ntg f 10.67 0.0   1   0.0 0.0 10.67, 10.67 -1.1
(B6.5XFAD x D2)F1-ADtg f 20.628 15.891   17 3.8542 0.7704 -0.52
(B6.5XFAD x D2)F1-ADtg m 30.881 16.883   8 5.9689 0.5467 4.0, 54.0 -0.45
(B6.5XFAD x D2)F1-Ntg f 41.237 21.689   12 6.2611 0.526 7.33, 74.67 0.69
(B6.5XFAD x D2)F1-Ntg m 39.422 29.35   4 14.675 0.7445 0.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 35.4156 6.5422 48.3083 22.5228
(B6.5XFAD x B6)F1-Ntg m 41.9555 5.9176 53.6174 30.2935
(B6.5XFAD x BXD100)F1-ADtg f 16.335 13.8781 43.6847 -11.0147
(B6.5XFAD x BXD100)F1-ADtg m 12.3914 7.4182 27.0105 -2.2276
(B6.5XFAD x BXD100)F1-Ntg f 27.435 9.8133 46.7742 8.0958
(B6.5XFAD x BXD100)F1-Ntg m 21.9417 8.0125 37.732 6.1513
(B6.5XFAD x BXD32)F1-ADtg f 30.665 13.8781 58.0147 3.3153
(B6.5XFAD x BXD32)F1-ADtg m 30.0 11.3314 52.3309 7.6691
(B6.5XFAD x BXD32)F1-Ntg f 6.89 11.3314 29.2209 -15.4409
(B6.5XFAD x BXD32)F1-Ntg m 32.665 13.8781 60.0147 5.3153
(B6.5XFAD x BXD44)F1-ADtg f 36.0523 5.4434 46.7797 25.3249
(B6.5XFAD x BXD44)F1-ADtg m 24.8587 6.9391 38.5336 11.1839
(B6.5XFAD x BXD60)F1-ADtg f 27.3325 9.8133 46.6717 7.9933
(B6.5XFAD x BXD60)F1-ADtg m 37.302 8.7773 54.5995 20.0045
(B6.5XFAD x BXD61)F1-ADtg f 29.4186 7.4182 44.0376 14.7995
(B6.5XFAD x BXD61)F1-ADtg m 56.5633 11.3314 78.8943 34.2324
(B6.5XFAD x BXD61)F1-Ntg f 60.932 8.7773 78.2295 43.6345
(B6.5XFAD x BXD61)F1-Ntg m 37.5233 8.0125 53.3137 21.733
(B6.5XFAD x BXD62)F1-ADtg f 12.5233 11.3314 34.8543 -9.8076
(B6.5XFAD x BXD62)F1-ADtg m 32.665 13.8781 60.0147 5.3153
(B6.5XFAD x BXD62)F1-Ntg f 49.43 11.3314 71.7609 27.0991
(B6.5XFAD x BXD62)F1-Ntg m 54.0 11.3314 76.3309 31.6691
(B6.5XFAD x BXD65)F1-ADtg f 46.505 8.0125 62.2954 30.7146
(B6.5XFAD x BXD65)F1-ADtg m 58.0 13.8781 85.3497 30.6503
(B6.5XFAD x BXD65)F1-Ntg f 43.5838 6.9391 57.2586 29.9089
(B6.5XFAD x BXD65)F1-Ntg m 60.0 13.8781 87.3497 32.6503
(B6.5XFAD x BXD66)F1-ADtg f 35.08 11.3314 57.4109 12.7491
(B6.5XFAD x BXD66)F1-ADtg m 43.004 8.7773 60.3015 25.7065
(B6.5XFAD x BXD68)F1-ADtg f 17.8433 11.3314 40.1743 -4.4876
(B6.5XFAD x BXD68)F1-ADtg m 35.8757 7.4182 50.4947 21.2567
(B6.5XFAD x BXD68)F1-Ntg f 40.768 6.2065 52.9992 28.5368
(B6.5XFAD x BXD68)F1-Ntg m 31.0 13.8781 58.3497 3.6503
(B6.5XFAD x BXD69)F1-ADtg f 30.0383 8.0125 45.8287 14.248
(B6.5XFAD x BXD69)F1-ADtg m 25.202 8.7773 42.4995 7.9045
(B6.5XFAD x BXD69)F1-Ntg f 29.775 9.8133 49.1142 10.4358
(B6.5XFAD x BXD69)F1-Ntg m 27.5933 8.0125 43.3837 11.803
(B6.5XFAD x BXD70)F1-Ntg f 48.0 11.3314 70.3309 25.6691
(B6.5XFAD x BXD70)F1-Ntg m 19.375 13.8781 46.7247 -7.9747
(B6.5XFAD x BXD75)F1-ADtg f 9.335 9.8133 28.6742 -10.0042
(B6.5XFAD x BXD75)F1-ADtg m 38.5225 9.8133 57.8617 19.1833
(B6.5XFAD x BXD77)F1-ADtg f 2.2367 11.3314 24.5676 -20.0943
(B6.5XFAD x BXD77)F1-ADtg m 36.0 11.3314 58.3309 13.6691
(B6.5XFAD x BXD77)F1-Ntg f 31.91 6.2065 44.1412 19.6788
(B6.5XFAD x BXD77)F1-Ntg m 18.9017 8.0125 34.692 3.1113
(B6.5XFAD x BXD87)F1-ADtg f 47.084 6.2065 59.3152 34.8528
(B6.5XFAD x BXD87)F1-ADtg m 28.11 9.8133 47.4492 8.7708
(B6.5XFAD x BXD89)F1-Ntg f 32.0 13.8781 59.3497 4.6503
(B6.5XFAD x BXD89)F1-Ntg m 37.0 13.8781 64.3497 9.6503
(B6.5XFAD x D2)F1-ADtg f 20.6282 4.7602 30.0091 11.2474
(B6.5XFAD x D2)F1-ADtg m 30.8813 6.9391 44.5561 17.2064
(B6.5XFAD x D2)F1-Ntg f 41.2367 5.6657 52.4021 30.0712
(B6.5XFAD x D2)F1-Ntg m 39.4225 9.8133 58.7617 20.0833


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 38.6855 4.4108 47.3778 29.9932
(B6.5XFAD x BXD100)F1-ADtg both 14.3632 7.8682 29.869 -1.1426
(B6.5XFAD x BXD100)F1-Ntg both 24.6883 6.3345 37.1717 12.205
(B6.5XFAD x BXD32)F1-ADtg both 30.3325 8.9583 47.9867 12.6783
(B6.5XFAD x BXD32)F1-Ntg both 19.7775 8.9583 37.4317 2.1233
(B6.5XFAD x BXD44)F1-ADtg both 30.4555 4.4097 39.1457 21.7653
(B6.5XFAD x BXD60)F1-ADtg both 32.3173 6.583 45.2904 19.3441
(B6.5XFAD x BXD61)F1-ADtg both 42.991 6.7718 56.3362 29.6457
(B6.5XFAD x BXD61)F1-Ntg both 49.2277 5.9423 60.9381 37.5172
(B6.5XFAD x BXD62)F1-ADtg both 22.5942 8.9583 40.2483 4.94
(B6.5XFAD x BXD62)F1-Ntg both 51.715 8.0125 67.5054 35.9246
(B6.5XFAD x BXD65)F1-ADtg both 52.2525 8.0125 68.0429 36.4621
(B6.5XFAD x BXD65)F1-Ntg both 51.7919 7.7581 67.0808 36.5029
(B6.5XFAD x BXD66)F1-ADtg both 39.042 7.1666 53.1653 24.9187
(B6.5XFAD x BXD68)F1-ADtg both 26.8595 6.7718 40.2048 13.5142
(B6.5XFAD x BXD68)F1-Ntg both 35.884 7.6014 50.864 20.904
(B6.5XFAD x BXD69)F1-ADtg both 27.6202 5.9423 39.3306 15.9097
(B6.5XFAD x BXD69)F1-Ntg both 28.6842 6.3345 41.1675 16.2008
(B6.5XFAD x BXD70)F1-Ntg both 33.6875 8.9583 51.3417 16.0333
(B6.5XFAD x BXD75)F1-ADtg both 23.9288 6.9391 37.6036 10.2539
(B6.5XFAD x BXD77)F1-ADtg both 19.1183 8.0125 34.9087 3.328
(B6.5XFAD x BXD77)F1-Ntg both 25.4058 5.0676 35.3925 15.4191
(B6.5XFAD x BXD87)F1-ADtg both 37.597 5.8056 49.0382 26.1558
(B6.5XFAD x BXD89)F1-Ntg both 34.5 9.8133 53.8392 15.1608
(B6.5XFAD x D2)F1-ADtg both 25.7547 4.2074 34.0463 17.4631
(B6.5XFAD x D2)F1-Ntg both 40.3296 5.6657 51.4951 29.1641




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA