Phenotype measure:   Neuner1   cfc_14mo_shock2

ID, description, units MPD:65969   cfc_14mo_shock2   percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning   [%]  2nd shock
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning 2nd shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means24.322   % 32.78   %
Median of the strain means23.956   % 29.336   %
SD of the strain means± 16.088 ± 13.755
Coefficient of variation (CV)0.6615 0.4196
Min–max range of strain means0.0   –   64.67   % 12.0   –   76.0   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2229.4564 2229.4564 6.2478 0.0132
strain 25 8411.7117 336.4685 0.9429 0.5459
sex:strain 25 18797.2144 751.8886 2.1071 0.0024
Residuals 222 79217.668 356.8363


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 36.924 24.17   27 4.6515 0.6546 0.3
(B6.5XFAD x B6)F1-Ntg f 27.203 17.63   9 5.8768 0.6481 2.67, 56.67 0.18
(B6.5XFAD x B6)F1-Ntg m 31.437 14.612   11 4.4058 0.4648 8.67, 54.0 -0.1
(B6.5XFAD x BXD100)F1-ADtg f 32.0 32.06   2   22.67 1.0019 9.33, 54.67 0.48
(B6.5XFAD x BXD100)F1-ADtg m 29.336 24.942   7 9.427 0.8502 2.67, 56.0 -0.25
(B6.5XFAD x BXD100)F1-Ntg f 30.165 10.711   4 5.3557 0.3551 20.67, 45.33 0.36
(B6.5XFAD x BXD100)F1-Ntg m 22.738 12.347   6 5.0408 0.543 6.0, 35.33 -0.73
(B6.5XFAD x BXD14)F1-ADtg f 1.68 2.3759   2   1.68 1.4142 -1.41
(B6.5XFAD x BXD14)F1-Ntg f 49.335 7.5448   2   5.335 0.1529 44.0, 54.67 1.55
(B6.5XFAD x BXD16)F1-ADtg f 21.832 9.0626   4 4.5313 0.4151 8.67, 29.33 -0.15
(B6.5XFAD x BXD22)F1-ADtg f 15.085 15.677   2   11.085 1.0392 4.0, 26.17 -0.57
(B6.5XFAD x BXD22)F1-Ntg f 17.0 24.042   2   17.0 1.4142 -0.46
(B6.5XFAD x BXD32)F1-ADtg f 1.335 1.888   2   1.335 1.4142 -1.43
(B6.5XFAD x BXD32)F1-ADtg m 37.777 11.042   3 6.3749 0.2923 27.33, 49.33 0.36
(B6.5XFAD x BXD32)F1-Ntg f 1.3333 2.3094   3 1.3333 1.7321 -1.43
(B6.5XFAD x BXD32)F1-Ntg m 59.0 15.556   2   11.0 0.2637 48.0, 70.0 1.91
(B6.5XFAD x BXD42)F1-ADtg f 41.665 40.072   2   28.335 0.9618 13.33, 70.0 1.08
(B6.5XFAD x BXD42)F1-Ntg f 0.0 0.0   1   0.0 None -1.51
(B6.5XFAD x BXD44)F1-ADtg f 28.724 23.745   13 6.5858 0.8267 3.33, 81.33 0.27
(B6.5XFAD x BXD44)F1-ADtg m 31.365 17.103   8 6.0468 0.5453 2.67, 49.33 -0.1
(B6.5XFAD x BXD44)F1-Ntg f 64.67 0.0   1   0.0 0.0 64.67, 64.67 2.51
(B6.5XFAD x BXD44)F1-Ntg m 27.557 18.384   3 10.614 0.6672 10.0, 46.67 -0.38
(B6.5XFAD x BXD51)F1-ADtg f 51.45 17.706   6 7.2285 0.3442 26.0, 78.0 1.69
(B6.5XFAD x BXD51)F1-Ntg f 19.332 16.733   4 8.3663 0.8655 -0.31
(B6.5XFAD x BXD55)F1-ADtg f 0.8325 1.665   4 0.8325 2.0 -1.46
(B6.5XFAD x BXD55)F1-Ntg f 2.0 2.8284   2   2.0 1.4142 -1.39
(B6.5XFAD x BXD56)F1-ADtg m 76.0 0.0   1   0.0 0.0 76.0, 76.0 3.14
(B6.5XFAD x BXD56)F1-Ntg f 32.0 37.717   2   26.67 1.1787 5.33, 58.67 0.48
(B6.5XFAD x BXD56)F1-Ntg m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.64
(B6.5XFAD x BXD60)F1-ADtg f 18.86 14.824   4 7.4118 0.786 -0.34
(B6.5XFAD x BXD60)F1-ADtg m 26.666 16.254   5 7.2691 0.6095 6.0, 44.0 -0.44
(B6.5XFAD x BXD60)F1-Ntg f 27.427 16.145   3 9.3214 0.5887 11.33, 43.62 0.19
(B6.5XFAD x BXD61)F1-ADtg f 26.531 22.034   7 8.3279 0.8305 0.14
(B6.5XFAD x BXD61)F1-ADtg m 52.67 7.8589   3 4.5373 0.1492 44.0, 59.33 1.45
(B6.5XFAD x BXD61)F1-Ntg f 49.8 10.865   5 4.8588 0.2182 38.67, 65.33 1.58
(B6.5XFAD x BXD61)F1-Ntg m 28.84 24.105   6 9.841 0.8358 -0.29
(B6.5XFAD x BXD62)F1-ADtg f 10.89 4.2868   3 2.475 0.3936 6.0, 14.0 -0.83
(B6.5XFAD x BXD62)F1-ADtg m 33.0 17.437   2   12.33 0.5284 20.67, 45.33 0.02
(B6.5XFAD x BXD62)F1-Ntg f 50.67 12.35   3 7.1303 0.2437 41.33, 64.67 1.64
(B6.5XFAD x BXD62)F1-Ntg m 42.113 24.888   3 14.369 0.591 14.0, 61.33 0.68
(B6.5XFAD x BXD65)F1-ADtg f 30.362 24.509   6 10.006 0.8072 0.38
(B6.5XFAD x BXD65)F1-ADtg m 30.335 5.1831   2   3.665 0.1709 26.67, 34.0 -0.18
(B6.5XFAD x BXD65)F1-Ntg f 27.634 20.227   8 7.1512 0.732 0.21
(B6.5XFAD x BXD65)F1-Ntg m 43.67 9.8995   2   7.0 0.2267 36.67, 50.67 0.79
(B6.5XFAD x BXD66)F1-ADtg f 19.11 10.007   3 5.7777 0.5237 9.33, 29.33 -0.32
(B6.5XFAD x BXD66)F1-ADtg m 28.8 25.994   5 11.625 0.9026 3.33, 64.67 -0.29
(B6.5XFAD x BXD66)F1-Ntg f 58.0 0.0   1   0.0 0.0 58.0, 58.0 2.09
(B6.5XFAD x BXD66)F1-Ntg m 23.553 20.004   3 11.549 0.8493 3.33, 43.33 -0.67
(B6.5XFAD x BXD68)F1-ADtg f 27.11 28.042   3 16.19 1.0344 0.17
(B6.5XFAD x BXD68)F1-ADtg m 25.073 16.833   7 6.3621 0.6713 11.33, 60.67 -0.56
(B6.5XFAD x BXD68)F1-Ntg f 32.4 24.709   10 7.8135 0.7626 4.0, 72.0 0.5
(B6.5XFAD x BXD68)F1-Ntg m 23.335 33.001   2   23.335 1.4142 -0.69
(B6.5XFAD x BXD69)F1-ADtg f 20.13 21.169   6 8.6422 1.0516 6.0, 62.67 -0.26
(B6.5XFAD x BXD69)F1-ADtg m 20.0 18.732   5 8.377 0.9366 -0.93
(B6.5XFAD x BXD69)F1-Ntg f 27.91 20.052   4 10.026 0.7185 0.22
(B6.5XFAD x BXD69)F1-Ntg m 20.152 13.814   6 5.6394 0.6855 -0.92
(B6.5XFAD x BXD70)F1-ADtg f 2.67 0.0   1   0.0 0.0 2.67, 2.67 -1.35
(B6.5XFAD x BXD70)F1-ADtg m 30.003 17.01   3 9.8206 0.5669 10.67, 42.67 -0.2
(B6.5XFAD x BXD70)F1-Ntg f 36.003 23.007   3 13.283 0.639 12.67, 58.67 0.73
(B6.5XFAD x BXD70)F1-Ntg m 28.335 11.787   2   8.335 0.416 20.0, 36.67 -0.32
(B6.5XFAD x BXD75)F1-ADtg f 12.685 18.56   4 9.2799 1.4631 -0.72
(B6.5XFAD x BXD75)F1-ADtg m 36.5 30.353   4 15.176 0.8316 20.0, 82.0 0.27
(B6.5XFAD x BXD75)F1-Ntg f 19.777 21.092   6 8.6109 1.0665 -0.28
(B6.5XFAD x BXD75)F1-Ntg m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -1.51
(B6.5XFAD x BXD77)F1-ADtg f 0.0 0.0   3 0.0 None -1.51
(B6.5XFAD x BXD77)F1-ADtg m 38.0 10.086   3 5.8232 0.2654 26.67, 46.0 0.38
(B6.5XFAD x BXD77)F1-Ntg f 21.541 20.458   10 6.4695 0.9497 -0.17
(B6.5XFAD x BXD77)F1-Ntg m 19.02 7.0188   6 2.8654 0.369 12.0, 32.0 -1.0
(B6.5XFAD x BXD81)F1-ADtg f 15.0 20.073   6 8.1947 1.3382 -0.58
(B6.5XFAD x BXD81)F1-Ntg f 22.666 26.638   5 11.913 1.1752 -0.1
(B6.5XFAD x BXD87)F1-ADtg f 34.668 11.804   10 3.7328 0.3405 16.67, 55.33 0.64
(B6.5XFAD x BXD87)F1-ADtg m 21.168 12.308   4 6.1542 0.5815 6.0, 33.33 -0.84
(B6.5XFAD x BXD87)F1-Ntg f 23.777 4.9122   3 2.8361 0.2066 20.0, 29.33 -0.03
(B6.5XFAD x BXD87)F1-Ntg m 61.33 0.0   1   0.0 0.0 61.33, 61.33 2.08
(B6.5XFAD x BXD89)F1-ADtg m 18.0 0.0   1   0.0 0.0 18.0, 18.0 -1.07
(B6.5XFAD x BXD89)F1-Ntg f 24.135 22.818   2   16.135 0.9454 8.0, 40.27 -0.01
(B6.5XFAD x BXD89)F1-Ntg m 38.665 7.5448   2   5.335 0.1951 33.33, 44.0 0.43
(B6.5XFAD x BXD99)F1-ADtg f 45.33 0.0   1   0.0 0.0 45.33, 45.33 1.31
(B6.5XFAD x BXD99)F1-Ntg f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.14
(B6.5XFAD x D2)F1-ADtg f 14.365 15.132   17 3.6701 1.0534 -0.62
(B6.5XFAD x D2)F1-ADtg m 50.45 22.169   8 7.838 0.4394 14.0, 78.67 1.28
(B6.5XFAD x D2)F1-Ntg f 24.358 19.963   12 5.7627 0.8196 3.33, 60.67 0.0
(B6.5XFAD x D2)F1-Ntg m 19.5 24.893   4 12.447 1.2766 -0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 27.2033 6.2967 39.6123 14.7944
(B6.5XFAD x B6)F1-Ntg m 31.4373 5.6956 42.6616 20.2129
(B6.5XFAD x BXD100)F1-ADtg f 32.0 13.3573 58.3234 5.6766
(B6.5XFAD x BXD100)F1-ADtg m 29.3357 7.1398 43.4062 15.2653
(B6.5XFAD x BXD100)F1-Ntg f 30.165 9.4451 48.7784 11.5516
(B6.5XFAD x BXD100)F1-Ntg m 22.7383 7.7119 37.9361 7.5405
(B6.5XFAD x BXD32)F1-ADtg f 1.335 13.3573 27.6584 -24.9884
(B6.5XFAD x BXD32)F1-ADtg m 37.7767 10.9062 59.2696 16.2837
(B6.5XFAD x BXD32)F1-Ntg f 1.3333 10.9062 22.8263 -20.1596
(B6.5XFAD x BXD32)F1-Ntg m 59.0 13.3573 85.3234 32.6766
(B6.5XFAD x BXD44)F1-ADtg f 28.7238 5.2392 39.0487 18.399
(B6.5XFAD x BXD44)F1-ADtg m 31.365 6.6787 44.5267 18.2033
(B6.5XFAD x BXD60)F1-ADtg f 18.86 9.4451 37.4734 0.2466
(B6.5XFAD x BXD60)F1-ADtg m 26.666 8.4479 43.3144 10.0176
(B6.5XFAD x BXD61)F1-ADtg f 26.5314 7.1398 40.6019 12.461
(B6.5XFAD x BXD61)F1-ADtg m 52.6667 10.9062 74.1596 31.1737
(B6.5XFAD x BXD61)F1-Ntg f 49.8 8.4479 66.4484 33.1516
(B6.5XFAD x BXD61)F1-Ntg m 28.84 7.7119 44.0378 13.6422
(B6.5XFAD x BXD62)F1-ADtg f 10.89 10.9062 32.383 -10.603
(B6.5XFAD x BXD62)F1-ADtg m 33.0 13.3573 59.3234 6.6766
(B6.5XFAD x BXD62)F1-Ntg f 50.6667 10.9062 72.1596 29.1737
(B6.5XFAD x BXD62)F1-Ntg m 42.1133 10.9062 63.6063 20.6204
(B6.5XFAD x BXD65)F1-ADtg f 30.3617 7.7119 45.5595 15.1639
(B6.5XFAD x BXD65)F1-ADtg m 30.335 13.3573 56.6584 4.0116
(B6.5XFAD x BXD65)F1-Ntg f 27.6337 6.6787 40.7954 14.4721
(B6.5XFAD x BXD65)F1-Ntg m 43.67 13.3573 69.9934 17.3466
(B6.5XFAD x BXD66)F1-ADtg f 19.11 10.9062 40.603 -2.383
(B6.5XFAD x BXD66)F1-ADtg m 28.8 8.4479 45.4484 12.1516
(B6.5XFAD x BXD68)F1-ADtg f 27.11 10.9062 48.603 5.617
(B6.5XFAD x BXD68)F1-ADtg m 25.0729 7.1398 39.1433 11.0024
(B6.5XFAD x BXD68)F1-Ntg f 32.4 5.9736 44.1722 20.6278
(B6.5XFAD x BXD68)F1-Ntg m 23.335 13.3573 49.6584 -2.9884
(B6.5XFAD x BXD69)F1-ADtg f 20.13 7.7119 35.3278 4.9322
(B6.5XFAD x BXD69)F1-ADtg m 20.0 8.4479 36.6484 3.3516
(B6.5XFAD x BXD69)F1-Ntg f 27.91 9.4451 46.5234 9.2966
(B6.5XFAD x BXD69)F1-Ntg m 20.1517 7.7119 35.3495 4.9539
(B6.5XFAD x BXD70)F1-Ntg f 36.0033 10.9062 57.4963 14.5104
(B6.5XFAD x BXD70)F1-Ntg m 28.335 13.3573 54.6584 2.0116
(B6.5XFAD x BXD75)F1-ADtg f 12.685 9.4451 31.2984 -5.9284
(B6.5XFAD x BXD75)F1-ADtg m 36.5 9.4451 55.1134 17.8866
(B6.5XFAD x BXD77)F1-ADtg f 0.0 10.9062 21.493 -21.493
(B6.5XFAD x BXD77)F1-ADtg m 38.0 10.9062 59.493 16.507
(B6.5XFAD x BXD77)F1-Ntg f 21.541 5.9736 33.3132 9.7688
(B6.5XFAD x BXD77)F1-Ntg m 19.02 7.7119 34.2178 3.8222
(B6.5XFAD x BXD87)F1-ADtg f 34.668 5.9736 46.4402 22.8958
(B6.5XFAD x BXD87)F1-ADtg m 21.1675 9.4451 39.7809 2.5541
(B6.5XFAD x BXD89)F1-Ntg f 24.135 13.3573 50.4584 -2.1884
(B6.5XFAD x BXD89)F1-Ntg m 38.665 13.3573 64.9884 12.3416
(B6.5XFAD x D2)F1-ADtg f 14.3647 4.5815 23.3936 5.3359
(B6.5XFAD x D2)F1-ADtg m 50.4513 6.6787 63.6129 37.2896
(B6.5XFAD x D2)F1-Ntg f 24.3575 5.4531 35.104 13.611
(B6.5XFAD x D2)F1-Ntg m 19.5 9.4451 38.1134 0.8866


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 29.3203 4.2452 37.6864 20.9542
(B6.5XFAD x BXD100)F1-ADtg both 30.6679 7.5729 45.5918 15.7439
(B6.5XFAD x BXD100)F1-Ntg both 26.4517 6.0968 38.4666 14.4367
(B6.5XFAD x BXD32)F1-ADtg both 19.5558 8.6221 36.5475 2.5642
(B6.5XFAD x BXD32)F1-Ntg both 30.1667 8.6221 47.1583 13.175
(B6.5XFAD x BXD44)F1-ADtg both 30.0444 4.2442 38.4085 21.6803
(B6.5XFAD x BXD60)F1-ADtg both 22.763 6.3359 35.2493 10.2767
(B6.5XFAD x BXD61)F1-ADtg both 39.599 6.5177 52.4435 26.7546
(B6.5XFAD x BXD61)F1-Ntg both 39.32 5.7193 50.591 28.049
(B6.5XFAD x BXD62)F1-ADtg both 21.945 8.6221 38.9367 4.9533
(B6.5XFAD x BXD62)F1-Ntg both 46.39 7.7119 61.5878 31.1922
(B6.5XFAD x BXD65)F1-ADtg both 30.3483 7.7119 45.5461 15.1505
(B6.5XFAD x BXD65)F1-Ntg both 35.6519 7.467 50.3671 20.9367
(B6.5XFAD x BXD66)F1-ADtg both 23.955 6.8977 37.5483 10.3617
(B6.5XFAD x BXD68)F1-ADtg both 26.0914 6.5177 38.9359 13.2469
(B6.5XFAD x BXD68)F1-Ntg both 27.8675 7.3161 42.2854 13.4496
(B6.5XFAD x BXD69)F1-ADtg both 20.065 5.7193 31.336 8.794
(B6.5XFAD x BXD69)F1-Ntg both 24.0308 6.0968 36.0458 12.0159
(B6.5XFAD x BXD70)F1-Ntg both 32.1692 8.6221 49.1608 15.1775
(B6.5XFAD x BXD75)F1-ADtg both 24.5925 6.6787 37.7542 11.4308
(B6.5XFAD x BXD77)F1-ADtg both 19.0 7.7119 34.1978 3.8022
(B6.5XFAD x BXD77)F1-Ntg both 20.2805 4.8774 29.8924 10.6686
(B6.5XFAD x BXD87)F1-ADtg both 27.9177 5.5878 38.9296 16.9059
(B6.5XFAD x BXD89)F1-Ntg both 31.4 9.4451 50.0134 12.7866
(B6.5XFAD x D2)F1-ADtg both 32.408 4.0495 40.3884 24.4275
(B6.5XFAD x D2)F1-Ntg both 21.9287 5.4531 32.6752 11.1823




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA