Project measure / variable:   Neuner1   cfc_14mo_shock1

ID, description, units MPD:65968   cfc_14mo_shock1   percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning   [%]  1st shock  
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning 1st shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means13.962   % 21.625   %
Median of the strain means8.9   % 20.0   %
SD of the strain means± 13.277 ± 14.429
Coefficient of variation (CV)0.9509 0.6673
Min–max range of strain means0.0   –   66.67   % 0.0   –   74.67   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2196.1397 2196.1397 8.1004 0.0048
strain 25 13794.6762 551.787 2.0352 0.0036
sex:strain 25 11449.9945 457.9998 1.6893 0.0252
Residuals 222 60187.8393 271.1164


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 31.595 23.923   27 4.604 0.7572 0.69
(B6.5XFAD x B6)F1-Ntg f 16.169 11.152   9 3.7174 0.6897 0.17
(B6.5XFAD x B6)F1-Ntg m 12.27 8.3825   11 2.5274 0.6832 -0.65
(B6.5XFAD x BXD100)F1-ADtg f 11.0 10.847   2   7.67 0.9861 3.33, 18.67 -0.22
(B6.5XFAD x BXD100)F1-ADtg m 26.254 28.389   7 10.73 1.0813 0.32
(B6.5XFAD x BXD100)F1-Ntg f 5.835 5.8982   4 2.9491 1.0108 2.67, 14.67 -0.61
(B6.5XFAD x BXD100)F1-Ntg m 13.782 17.777   6 7.2574 1.2899 -0.54
(B6.5XFAD x BXD14)F1-ADtg f 8.0 11.314   2   8.0 1.4142 -0.45
(B6.5XFAD x BXD14)F1-Ntg f 9.0 12.728   2   9.0 1.4142 -0.37
(B6.5XFAD x BXD16)F1-ADtg f 18.52 15.116   4 7.5581 0.8162 0.34
(B6.5XFAD x BXD22)F1-ADtg f 7.665 10.84   2   7.665 1.4142 -0.47
(B6.5XFAD x BXD22)F1-Ntg f 44.67 48.083   2   34.0 1.0764 10.67, 78.67 2.31
(B6.5XFAD x BXD32)F1-ADtg f 27.67 24.042   2   17.0 0.8689 10.67, 44.67 1.03
(B6.5XFAD x BXD32)F1-ADtg m 19.837 7.867   3 4.542 0.3966 11.33, 26.85 -0.12
(B6.5XFAD x BXD32)F1-Ntg f 0.0 0.0   3 0.0 None -1.05
(B6.5XFAD x BXD32)F1-Ntg m 12.67 8.4853   2   6.0 0.6697 6.67, 18.67 -0.62
(B6.5XFAD x BXD42)F1-ADtg f 23.665 33.467   2   23.665 1.4142 0.73
(B6.5XFAD x BXD42)F1-Ntg f 0.0 0.0   1   0.0 None -1.05
(B6.5XFAD x BXD44)F1-ADtg f 31.289 24.153   13 6.6989 0.7719 1.34, 85.33 1.31
(B6.5XFAD x BXD44)F1-ADtg m 21.834 14.872   8 5.2582 0.6812 9.33, 54.0 0.01
(B6.5XFAD x BXD44)F1-Ntg f 16.67 0.0   1   0.0 0.0 16.67, 16.67 0.2
(B6.5XFAD x BXD44)F1-Ntg m 20.443 19.66   3 11.351 0.9617 5.33, 42.67 -0.08
(B6.5XFAD x BXD51)F1-ADtg f 44.663 25.889   6 10.569 0.5797 7.33, 71.33 2.31
(B6.5XFAD x BXD51)F1-Ntg f 0.8325 1.665   4 0.8325 2.0 -0.99
(B6.5XFAD x BXD55)F1-ADtg f 1.0 2.0   4 1.0 2.0 -0.98
(B6.5XFAD x BXD55)F1-Ntg f 1.665 2.3547   2   1.665 1.4142 -0.93
(B6.5XFAD x BXD56)F1-ADtg m 74.67 0.0   1   0.0 0.0 74.67, 74.67 3.68
(B6.5XFAD x BXD56)F1-Ntg f 8.39 11.865   2   8.39 1.4142 -0.42
(B6.5XFAD x BXD56)F1-Ntg m 2.67 0.0   1   0.0 0.0 2.67, 2.67 -1.31
(B6.5XFAD x BXD60)F1-ADtg f 11.335 18.493   4 9.2463 1.6315 -0.2
(B6.5XFAD x BXD60)F1-ADtg m 17.116 19.583   5 8.7578 1.1441 -0.31
(B6.5XFAD x BXD60)F1-Ntg f 3.7867 0.39577   3 0.2285 0.1045 3.33, 4.03 -0.77
(B6.5XFAD x BXD61)F1-ADtg f 22.02 25.077   7 9.4784 1.1389 0.61
(B6.5XFAD x BXD61)F1-ADtg m 35.18 4.5863   3 2.6479 0.1304 30.87, 40.0 0.94
(B6.5XFAD x BXD61)F1-Ntg f 24.856 12.163   5 5.4393 0.4893 14.67, 41.61 0.82
(B6.5XFAD x BXD61)F1-Ntg m 14.235 11.913   6 4.8634 0.8369 -0.51
(B6.5XFAD x BXD62)F1-ADtg f 3.5733 4.1003   3 2.3673 1.1475 -0.78
(B6.5XFAD x BXD62)F1-ADtg m 7.72 3.3234   2   2.35 0.4305 5.37, 10.07 -0.96
(B6.5XFAD x BXD62)F1-Ntg f 24.707 9.2003   3 5.3118 0.3724 19.33, 35.33 0.81
(B6.5XFAD x BXD62)F1-Ntg m 28.447 9.1   3 5.2539 0.3199 18.67, 36.67 0.47
(B6.5XFAD x BXD65)F1-ADtg f 7.455 12.334   6 5.0352 1.6544 -0.49
(B6.5XFAD x BXD65)F1-ADtg m 25.335 15.083   2   10.665 0.5953 14.67, 36.0 0.26
(B6.5XFAD x BXD65)F1-Ntg f 4.6712 7.8737   8 2.7838 1.6856 -0.7
(B6.5XFAD x BXD65)F1-Ntg m 30.665 43.367   2   30.665 1.4142 0.63
(B6.5XFAD x BXD66)F1-ADtg f 27.833 26.973   3 15.573 0.9691 6.04, 58.0 1.04
(B6.5XFAD x BXD66)F1-ADtg m 25.23 18.308   5 8.1875 0.7256 0.25
(B6.5XFAD x BXD66)F1-Ntg f 18.67 0.0   1   0.0 0.0 18.67, 18.67 0.35
(B6.5XFAD x BXD66)F1-Ntg m 8.0 1.7632   3 1.018 0.2204 6.67, 10.0 -0.94
(B6.5XFAD x BXD68)F1-ADtg f 4.6767 0.66531   3 0.38412 0.1423 4.0, 5.33 -0.7
(B6.5XFAD x BXD68)F1-ADtg m 20.15 9.7909   7 3.7006 0.4859 9.33, 34.67 -0.1
(B6.5XFAD x BXD68)F1-Ntg f 18.409 19.272   10 6.0944 1.0469 0.33
(B6.5XFAD x BXD68)F1-Ntg m 20.0 28.284   2   20.0 1.4142 -0.11
(B6.5XFAD x BXD69)F1-ADtg f 7.9033 3.0397   6 1.241 0.3846 2.67, 11.41 -0.46
(B6.5XFAD x BXD69)F1-ADtg m 22.966 10.81   5 4.8342 0.4707 8.67, 38.67 0.09
(B6.5XFAD x BXD69)F1-Ntg f 6.845 9.4348   4 4.7174 1.3784 -0.54
(B6.5XFAD x BXD69)F1-Ntg m 5.2283 6.7523   6 2.7566 1.2915 -1.14
(B6.5XFAD x BXD70)F1-ADtg f 2.68 0.0   1   0.0 0.0 2.68, 2.68 -0.85
(B6.5XFAD x BXD70)F1-ADtg m 37.553 22.333   3 12.894 0.5947 24.0, 63.33 1.1
(B6.5XFAD x BXD70)F1-Ntg f 21.11 21.189   3 12.233 1.0037 6.0, 45.33 0.54
(B6.5XFAD x BXD70)F1-Ntg m 5.025 3.3305   2   2.355 0.6628 2.67, 7.38 -1.15
(B6.5XFAD x BXD75)F1-ADtg f 11.832 23.665   4 11.832 2.0 -0.16
(B6.5XFAD x BXD75)F1-ADtg m 37.555 20.538   4 10.269 0.5469 13.33, 63.33 1.1
(B6.5XFAD x BXD75)F1-Ntg f 4.2217 3.4932   6 1.4261 0.8274 -0.73
(B6.5XFAD x BXD75)F1-Ntg m 17.33 0.0   1   0.0 0.0 17.33, 17.33 -0.3
(B6.5XFAD x BXD77)F1-ADtg f 13.187 9.1521   3 5.2839 0.694 6.0, 23.49 -0.06
(B6.5XFAD x BXD77)F1-ADtg m 38.0 32.258   3 18.624 0.8489 14.0, 74.67 1.13
(B6.5XFAD x BXD77)F1-Ntg f 8.8 10.875   10 3.4391 1.2358 -0.39
(B6.5XFAD x BXD77)F1-Ntg m 12.682 16.818   6 6.866 1.3262 -0.62
(B6.5XFAD x BXD81)F1-ADtg f 1.445 3.5395   6 1.445 2.4495 -0.94
(B6.5XFAD x BXD81)F1-Ntg f 7.6 7.4752   5 3.343 0.9836 -0.48
(B6.5XFAD x BXD87)F1-ADtg f 25.868 12.92   10 4.0855 0.4994 7.33, 46.67 0.9
(B6.5XFAD x BXD87)F1-ADtg m 7.8675 5.9274   4 2.9637 0.7534 -0.95
(B6.5XFAD x BXD87)F1-Ntg f 9.34 6.1046   3 3.5245 0.6536 2.68, 14.67 -0.35
(B6.5XFAD x BXD87)F1-Ntg m 17.33 0.0   1   0.0 0.0 17.33, 17.33 -0.3
(B6.5XFAD x BXD89)F1-ADtg m 0.0 0.0   1   0.0 None -1.5
(B6.5XFAD x BXD89)F1-Ntg f 6.69 0.02828   2   0.02 0.0042 6.67, 6.71 -0.55
(B6.5XFAD x BXD89)F1-Ntg m 26.0 2.8284   2   2.0 0.1088 24.0, 28.0 0.3
(B6.5XFAD x BXD99)F1-ADtg f 66.67 0.0   1   0.0 0.0 66.67, 66.67 3.97
(B6.5XFAD x BXD99)F1-Ntg f 4.03 0.0   1   0.0 0.0 4.03, 4.03 -0.75
(B6.5XFAD x D2)F1-ADtg f 15.925 15.077   17 3.6567 0.9467 0.15
(B6.5XFAD x D2)F1-ADtg m 46.064 29.685   8 10.495 0.6444 12.08, 86.67 1.69
(B6.5XFAD x D2)F1-Ntg f 7.3342 11.6   12 3.3485 1.5816 -0.5
(B6.5XFAD x D2)F1-Ntg m 15.165 19.703   4 9.8517 1.2993 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 16.1689 5.4885 26.9852 5.3526
(B6.5XFAD x B6)F1-Ntg m 12.27 4.9646 22.0537 2.4863
(B6.5XFAD x BXD100)F1-ADtg f 11.0 11.6429 33.9448 -11.9448
(B6.5XFAD x BXD100)F1-ADtg m 26.2543 6.2234 38.5188 13.9898
(B6.5XFAD x BXD100)F1-Ntg f 5.835 8.2328 22.0595 -10.3895
(B6.5XFAD x BXD100)F1-Ntg m 13.7817 6.7221 27.0289 0.5345
(B6.5XFAD x BXD32)F1-ADtg f 27.67 11.6429 50.6148 4.7252
(B6.5XFAD x BXD32)F1-ADtg m 19.8367 9.5064 38.5711 1.1023
(B6.5XFAD x BXD32)F1-Ntg f 0.0 9.5064 18.7344 -18.7344
(B6.5XFAD x BXD32)F1-Ntg m 12.67 11.6429 35.6148 -10.2748
(B6.5XFAD x BXD44)F1-ADtg f 31.2892 4.5667 40.2889 22.2895
(B6.5XFAD x BXD44)F1-ADtg m 21.8338 5.8215 33.3062 10.3613
(B6.5XFAD x BXD60)F1-ADtg f 11.335 8.2328 27.5595 -4.8895
(B6.5XFAD x BXD60)F1-ADtg m 17.116 7.3636 31.6276 2.6044
(B6.5XFAD x BXD61)F1-ADtg f 22.02 6.2234 34.2845 9.7555
(B6.5XFAD x BXD61)F1-ADtg m 35.18 9.5064 53.9144 16.4456
(B6.5XFAD x BXD61)F1-Ntg f 24.856 7.3636 39.3676 10.3444
(B6.5XFAD x BXD61)F1-Ntg m 14.235 6.7221 27.4822 0.9878
(B6.5XFAD x BXD62)F1-ADtg f 3.5733 9.5064 22.3077 -15.1611
(B6.5XFAD x BXD62)F1-ADtg m 7.72 11.6429 30.6648 -15.2248
(B6.5XFAD x BXD62)F1-Ntg f 24.7067 9.5064 43.4411 5.9723
(B6.5XFAD x BXD62)F1-Ntg m 28.4467 9.5064 47.1811 9.7123
(B6.5XFAD x BXD65)F1-ADtg f 7.455 6.7221 20.7022 -5.7922
(B6.5XFAD x BXD65)F1-ADtg m 25.335 11.6429 48.2798 2.3902
(B6.5XFAD x BXD65)F1-Ntg f 4.6713 5.8215 16.1437 -6.8012
(B6.5XFAD x BXD65)F1-Ntg m 30.665 11.6429 53.6098 7.7202
(B6.5XFAD x BXD66)F1-ADtg f 27.8333 9.5064 46.5677 9.0989
(B6.5XFAD x BXD66)F1-ADtg m 25.23 7.3636 39.7416 10.7184
(B6.5XFAD x BXD68)F1-ADtg f 4.6767 9.5064 23.4111 -14.0577
(B6.5XFAD x BXD68)F1-ADtg m 20.15 6.2234 32.4145 7.8855
(B6.5XFAD x BXD68)F1-Ntg f 18.409 5.2069 28.6702 8.1478
(B6.5XFAD x BXD68)F1-Ntg m 20.0 11.6429 42.9448 -2.9448
(B6.5XFAD x BXD69)F1-ADtg f 7.9033 6.7221 21.1505 -5.3439
(B6.5XFAD x BXD69)F1-ADtg m 22.966 7.3636 37.4776 8.4544
(B6.5XFAD x BXD69)F1-Ntg f 6.845 8.2328 23.0695 -9.3795
(B6.5XFAD x BXD69)F1-Ntg m 5.2283 6.7221 18.4755 -8.0189
(B6.5XFAD x BXD70)F1-Ntg f 21.11 9.5064 39.8444 2.3756
(B6.5XFAD x BXD70)F1-Ntg m 5.025 11.6429 27.9698 -17.9198
(B6.5XFAD x BXD75)F1-ADtg f 11.8325 8.2328 28.057 -4.392
(B6.5XFAD x BXD75)F1-ADtg m 37.555 8.2328 53.7795 21.3305
(B6.5XFAD x BXD77)F1-ADtg f 13.1867 9.5064 31.9211 -5.5477
(B6.5XFAD x BXD77)F1-ADtg m 38.0 9.5064 56.7344 19.2656
(B6.5XFAD x BXD77)F1-Ntg f 8.8 5.2069 19.0612 -1.4612
(B6.5XFAD x BXD77)F1-Ntg m 12.6817 6.7221 25.9289 -0.5655
(B6.5XFAD x BXD87)F1-ADtg f 25.868 5.2069 36.1292 15.6068
(B6.5XFAD x BXD87)F1-ADtg m 7.8675 8.2328 24.092 -8.357
(B6.5XFAD x BXD89)F1-Ntg f 6.69 11.6429 29.6348 -16.2548
(B6.5XFAD x BXD89)F1-Ntg m 26.0 11.6429 48.9448 3.0552
(B6.5XFAD x D2)F1-ADtg f 15.9253 3.9935 23.7953 8.0553
(B6.5XFAD x D2)F1-ADtg m 46.0638 5.8215 57.5362 34.5913
(B6.5XFAD x D2)F1-Ntg f 7.3342 4.7532 16.7014 -2.033
(B6.5XFAD x D2)F1-Ntg m 15.165 8.2328 31.3895 -1.0595


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 14.2194 3.7004 21.5118 6.9271
(B6.5XFAD x BXD100)F1-ADtg both 18.6271 6.6009 31.6356 5.6186
(B6.5XFAD x BXD100)F1-Ntg both 9.8083 5.3143 20.2812 -0.6645
(B6.5XFAD x BXD32)F1-ADtg both 23.7533 7.5155 38.5642 8.9425
(B6.5XFAD x BXD32)F1-Ntg both 6.335 7.5155 21.1458 -8.4758
(B6.5XFAD x BXD44)F1-ADtg both 26.5615 3.6995 33.8521 19.2709
(B6.5XFAD x BXD60)F1-ADtg both 14.2255 5.5227 25.1092 3.3418
(B6.5XFAD x BXD61)F1-ADtg both 28.6 5.6812 39.7959 17.4041
(B6.5XFAD x BXD61)F1-Ntg both 19.5455 4.9852 29.3699 9.7211
(B6.5XFAD x BXD62)F1-ADtg both 5.6467 7.5155 20.4575 -9.1642
(B6.5XFAD x BXD62)F1-Ntg both 26.5767 6.7221 39.8239 13.3295
(B6.5XFAD x BXD65)F1-ADtg both 16.395 6.7221 29.6422 3.1478
(B6.5XFAD x BXD65)F1-Ntg both 17.6681 6.5086 30.4947 4.8416
(B6.5XFAD x BXD66)F1-ADtg both 26.5317 6.0124 38.3803 14.683
(B6.5XFAD x BXD68)F1-ADtg both 12.4133 5.6812 23.6093 1.2174
(B6.5XFAD x BXD68)F1-Ntg both 19.2045 6.3771 31.7719 6.6371
(B6.5XFAD x BXD69)F1-ADtg both 15.4347 4.9852 25.2591 5.6103
(B6.5XFAD x BXD69)F1-Ntg both 6.0367 5.3143 16.5095 -4.4362
(B6.5XFAD x BXD70)F1-Ntg both 13.0675 7.5155 27.8783 -1.7433
(B6.5XFAD x BXD75)F1-ADtg both 24.6937 5.8215 36.1662 13.2213
(B6.5XFAD x BXD77)F1-ADtg both 25.5933 6.7221 38.8405 12.3461
(B6.5XFAD x BXD77)F1-Ntg both 10.7408 4.2514 19.1191 2.3626
(B6.5XFAD x BXD87)F1-ADtg both 16.8678 4.8706 26.4663 7.2692
(B6.5XFAD x BXD89)F1-Ntg both 16.345 8.2328 32.5695 0.1205
(B6.5XFAD x D2)F1-ADtg both 30.9945 3.5298 37.9507 24.0383
(B6.5XFAD x D2)F1-Ntg both 11.2496 4.7532 20.6168 1.8824




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA