Project measure / variable:   Neuner1   cfc_6mo_shock3

ID, description, units MPD:65965   cfc_6mo_shock3   percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning   [%]  3rd shock  
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning 3rd shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means37.443   % 31.473   %
Median of the strain means36.7   % 35.027   %
SD of the strain means± 15.714 ± 16.045
Coefficient of variation (CV)0.4197 0.5098
Min–max range of strain means11.41   –   81.88   % 0.0   –   58.18   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 127.5252 127.5252 0.2915 0.5905
strain 13 10253.4168 788.7244 1.803 0.0535
sex:strain 13 1706.2079 131.2468 0.3 0.9908
Residuals 95 41557.4984 437.4474


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 47.17 5.4306   2   3.84 0.1151 43.33, 51.01 0.62
(B6.5XFAD x B6)F1-ADtg m 49.099 10.002   7 3.7804 0.2037 37.33, 62.42 1.1
(B6.5XFAD x B6)F1-Ntg f 37.142 18.06   6 7.3729 0.4862 6.0, 54.0 -0.02
(B6.5XFAD x B6)F1-Ntg m 43.68 27.678   4 13.839 0.6337 8.72, 66.44 0.76
(B6.5XFAD x BXD100)F1-ADtg f 19.633 14.491   4 7.2454 0.7381 4.7, 36.24 -1.13
(B6.5XFAD x BXD100)F1-ADtg m 9.665 13.668   2   9.665 1.4142 -1.36
(B6.5XFAD x BXD100)F1-Ntg f 38.0 32.994   2   23.33 0.8683 14.67, 61.33 0.04
(B6.5XFAD x BXD14)F1-ADtg f 33.066 10.557   5 4.7212 0.3193 16.67, 44.67 -0.28
(B6.5XFAD x BXD14)F1-Ntg f 48.0 29.232   2   20.67 0.609 27.33, 68.67 0.67
(B6.5XFAD x BXD16)F1-ADtg f 26.5 15.089   4 7.5443 0.5694 12.0, 44.0 -0.7
(B6.5XFAD x BXD22)F1-ADtg f 17.113 12.671   3 7.3155 0.7404 4.67, 30.0 -1.29
(B6.5XFAD x BXD22)F1-Ntg f 57.33 0.0   1   0.0 0.0 57.33, 57.33 1.27
(B6.5XFAD x BXD2)F1-ADtg f 21.832 23.646   4 11.823 1.0831 -0.99
(B6.5XFAD x BXD2)F1-Ntg f 41.928 10.692   5 4.7817 0.255 28.0, 54.0 0.29
(B6.5XFAD x BXD32)F1-ADtg f 25.675 27.905   4 13.953 1.0869 -0.75
(B6.5XFAD x BXD32)F1-ADtg m 23.72 11.71   2   8.28 0.4937 15.44, 32.0 -0.48
(B6.5XFAD x BXD32)F1-Ntg f 22.15 0.0   1   0.0 0.0 22.15, 22.15 -0.97
(B6.5XFAD x BXD32)F1-Ntg m 42.665 7.5448   2   5.335 0.1768 37.33, 48.0 0.7
(B6.5XFAD x BXD34)F1-ADtg f 38.923 16.307   9 5.4358 0.419 4.0, 52.67 0.09
(B6.5XFAD x BXD34)F1-Ntg f 47.309 20.175   11 6.083 0.4265 22.0, 70.67 0.63
(B6.5XFAD x BXD42)F1-ADtg f 23.162 15.748   6 6.4293 0.6799 4.0, 45.64 -0.91
(B6.5XFAD x BXD42)F1-Ntg f 16.503 17.718   4 8.859 1.0737 -1.33
(B6.5XFAD x BXD44)F1-ADtg f 59.19 3.0264   2   2.14 0.0511 57.05, 61.33 1.38
(B6.5XFAD x BXD44)F1-ADtg m 50.34 0.47376   2   0.335 0.0094 50.0, 50.67 1.18
(B6.5XFAD x BXD44)F1-Ntg f 67.0 7.0711   2   5.0 0.1055 62.0, 72.0 1.88
(B6.5XFAD x BXD44)F1-Ntg m 17.33 0.0   1   0.0 0.0 17.33, 17.33 -0.88
(B6.5XFAD x BXD51)F1-ADtg f 45.113 26.945   3 15.557 0.5973 14.0, 60.67 0.49
(B6.5XFAD x BXD51)F1-Ntg f 58.0 11.679   3 6.7431 0.2014 46.67, 70.0 1.31
(B6.5XFAD x BXD55)F1-ADtg f 32.89 28.678   3 16.557 0.8719 -0.29
(B6.5XFAD x BXD55)F1-Ntg f 36.59 18.77   4 9.3852 0.513 25.5, 64.67 -0.05
(B6.5XFAD x BXD56)F1-ADtg f 28.33 9.8995   2   7.0 0.3494 21.33, 35.33 -0.58
(B6.5XFAD x BXD56)F1-Ntg f 38.717 20.926   3 12.082 0.5405 21.48, 62.0 0.08
(B6.5XFAD x BXD60)F1-ADtg f 53.66 3.3022   2   2.335 0.0615 51.33, 56.0 1.03
(B6.5XFAD x BXD60)F1-ADtg m 39.53 26.672   2   18.86 0.6747 20.67, 58.39 0.5
(B6.5XFAD x BXD60)F1-Ntg f 22.67 14.142   2   10.0 0.6238 12.67, 32.67 -0.94
(B6.5XFAD x BXD61)F1-ADtg f 29.53 41.762   2   29.53 1.4142 -0.5
(B6.5XFAD x BXD61)F1-ADtg m 29.67 7.0711   2   5.0 0.2383 24.67, 34.67 -0.11
(B6.5XFAD x BXD61)F1-Ntg f 81.88 0.0   1   0.0 0.0 81.88, 81.88 2.83
(B6.5XFAD x BXD61)F1-Ntg m 41.335 12.254   2   8.665 0.2965 32.67, 50.0 0.61
(B6.5XFAD x BXD62)F1-ADtg f 17.33 0.0   1   0.0 0.0 17.33, 17.33 -1.28
(B6.5XFAD x BXD62)F1-ADtg m 47.0 4.2426   2   3.0 0.0903 44.0, 50.0 0.97
(B6.5XFAD x BXD62)F1-Ntg f 45.0 26.87   2   19.0 0.5971 26.0, 64.0 0.48
(B6.5XFAD x BXD62)F1-Ntg m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -1.59
(B6.5XFAD x BXD65)F1-ADtg f 23.553 30.001   3 17.321 1.2738 -0.88
(B6.5XFAD x BXD65)F1-ADtg m 45.76 24.848   2   17.57 0.543 28.19, 63.33 0.89
(B6.5XFAD x BXD65)F1-Ntg f 67.33 0.0   1   0.0 0.0 67.33, 67.33 1.9
(B6.5XFAD x BXD65)F1-Ntg m 46.668 22.412   4 11.206 0.4802 18.0, 70.67 0.95
(B6.5XFAD x BXD66)F1-ADtg f 12.08 0.0   1   0.0 0.0 12.08, 12.08 -1.61
(B6.5XFAD x BXD66)F1-ADtg m 58.18 21.466   4 10.733 0.369 26.67, 71.81 1.66
(B6.5XFAD x BXD66)F1-Ntg f 52.67 0.0   1   0.0 0.0 52.67, 52.67 0.97
(B6.5XFAD x BXD66)F1-Ntg m 26.67 0.0   1   0.0 0.0 26.67, 26.67 -0.3
(B6.5XFAD x BXD68)F1-ADtg f 32.927 22.68   6 9.2589 0.6888 4.0, 55.33 -0.29
(B6.5XFAD x BXD68)F1-ADtg m 0.0 0.0   1   0.0 None -1.96
(B6.5XFAD x BXD68)F1-Ntg f 38.187 13.89   9 4.6301 0.3637 12.0, 59.33 0.05
(B6.5XFAD x BXD68)F1-Ntg m 26.67 0.0   2   0.0 0.0 26.67, 26.67 -0.3
(B6.5XFAD x BXD69)F1-ADtg f 26.845 1.9021   2   1.345 0.0709 25.5, 28.19 -0.67
(B6.5XFAD x BXD69)F1-ADtg m 30.67 0.0   1   0.0 0.0 30.67, 30.67 -0.05
(B6.5XFAD x BXD69)F1-Ntg f 48.32 0.0   1   0.0 0.0 48.32, 48.32 0.69
(B6.5XFAD x BXD75)F1-ADtg f 30.732 17.04   4 8.52 0.5545 6.67, 45.33 -0.43
(B6.5XFAD x BXD75)F1-ADtg m 17.0 22.161   2   15.67 1.3036 1.33, 32.67 -0.9
(B6.5XFAD x BXD75)F1-Ntg f 54.0 2.9033   3 1.6762 0.0538 50.67, 56.0 1.05
(B6.5XFAD x BXD75)F1-Ntg m 30.67 0.0   1   0.0 0.0 30.67, 30.67 -0.05
(B6.5XFAD x BXD77)F1-ADtg f 36.81 8.6833   2   6.14 0.2359 30.67, 42.95 -0.04
(B6.5XFAD x BXD77)F1-ADtg m 2.68 0.0   1   0.0 0.0 2.68, 2.68 -1.79
(B6.5XFAD x BXD77)F1-Ntg f 11.41 7.5943   2   5.37 0.6656 6.04, 16.78 -1.66
(B6.5XFAD x BXD77)F1-Ntg m 9.335 13.202   2   9.335 1.4142 -1.38
(B6.5XFAD x BXD81)F1-ADtg f 14.667 6.6412   6 2.7113 0.4528 6.0, 22.67 -1.45
(B6.5XFAD x BXD81)F1-Ntg f 30.443 17.716   3 10.229 0.5819 12.0, 47.33 -0.45
(B6.5XFAD x BXD87)F1-ADtg f 44.0 6.9605   3 4.0187 0.1582 39.33, 52.0 0.42
(B6.5XFAD x BXD87)F1-ADtg m 39.33 0.0   1   0.0 0.0 39.33, 39.33 0.49
(B6.5XFAD x BXD87)F1-Ntg f 45.337 28.729   3 16.586 0.6337 12.67, 66.67 0.5
(B6.5XFAD x BXD87)F1-Ntg m 42.553 29.427   3 16.99 0.6915 10.67, 68.67 0.69
(B6.5XFAD x BXD99)F1-ADtg f 57.93 11.295   3 6.5213 0.195 46.0, 68.46 1.3
(B6.5XFAD x D2)F1-ADtg f 31.996 20.247   16 5.0618 0.6328 -0.35
(B6.5XFAD x D2)F1-ADtg m 35.027 22.825   13 6.3305 0.6516 4.67, 63.33 0.22
(B6.5XFAD x D2)F1-Ntg f 35.589 26.252   11 7.9151 0.7376 -0.12
(B6.5XFAD x D2)F1-Ntg m 38.53 20.538   8 7.2614 0.5331 16.0, 76.0 0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 47.17 14.7893 76.5305 17.8095
(B6.5XFAD x B6)F1-ADtg m 49.0986 7.9052 64.7924 33.4047
(B6.5XFAD x B6)F1-Ntg f 37.1417 8.5386 54.093 20.1904
(B6.5XFAD x B6)F1-Ntg m 43.68 10.4576 64.441 22.919
(B6.5XFAD x BXD100)F1-ADtg f 19.6325 10.4576 40.3935 -1.1285
(B6.5XFAD x BXD100)F1-ADtg m 9.665 14.7893 39.0255 -19.6955
(B6.5XFAD x BXD32)F1-ADtg f 25.675 10.4576 46.436 4.914
(B6.5XFAD x BXD32)F1-ADtg m 23.72 14.7893 53.0805 -5.6405
(B6.5XFAD x BXD44)F1-ADtg f 59.19 14.7893 88.5505 29.8295
(B6.5XFAD x BXD44)F1-ADtg m 50.335 14.7893 79.6955 20.9745
(B6.5XFAD x BXD60)F1-ADtg f 53.665 14.7893 83.0255 24.3045
(B6.5XFAD x BXD60)F1-ADtg m 39.53 14.7893 68.8905 10.1695
(B6.5XFAD x BXD61)F1-ADtg f 29.53 14.7893 58.8905 0.1695
(B6.5XFAD x BXD61)F1-ADtg m 29.67 14.7893 59.0305 0.3095
(B6.5XFAD x BXD65)F1-ADtg f 23.5533 12.0754 47.5261 -0.4194
(B6.5XFAD x BXD65)F1-ADtg m 45.76 14.7893 75.1205 16.3995
(B6.5XFAD x BXD68)F1-Ntg f 38.1867 6.9717 52.0273 24.346
(B6.5XFAD x BXD68)F1-Ntg m 26.67 14.7893 56.0305 -2.6905
(B6.5XFAD x BXD75)F1-ADtg f 30.7325 10.4576 51.4935 9.9715
(B6.5XFAD x BXD75)F1-ADtg m 17.0 14.7893 46.3605 -12.3605
(B6.5XFAD x BXD77)F1-Ntg f 11.41 14.7893 40.7705 -17.9505
(B6.5XFAD x BXD77)F1-Ntg m 9.335 14.7893 38.6955 -20.0255
(B6.5XFAD x BXD87)F1-Ntg f 45.3367 12.0754 69.3094 21.3639
(B6.5XFAD x BXD87)F1-Ntg m 42.5533 12.0754 66.5261 18.5806
(B6.5XFAD x D2)F1-ADtg f 31.9963 5.2288 42.3768 21.6157
(B6.5XFAD x D2)F1-ADtg m 35.0269 5.8008 46.5431 23.5108
(B6.5XFAD x D2)F1-Ntg f 35.5891 6.3062 48.1084 23.0697
(B6.5XFAD x D2)F1-Ntg m 38.53 7.3947 53.2102 23.8498


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 48.1343 8.3848 64.7801 31.4885
(B6.5XFAD x B6)F1-Ntg both 40.4108 6.7504 53.812 27.0097
(B6.5XFAD x BXD100)F1-ADtg both 14.6487 9.0566 32.6283 -3.3308
(B6.5XFAD x BXD32)F1-ADtg both 24.6975 9.0566 42.6771 6.7179
(B6.5XFAD x BXD44)F1-ADtg both 54.7625 10.4576 75.5235 34.0015
(B6.5XFAD x BXD60)F1-ADtg both 46.5975 10.4576 67.3585 25.8365
(B6.5XFAD x BXD61)F1-ADtg both 29.6 10.4576 50.361 8.839
(B6.5XFAD x BXD65)F1-ADtg both 34.6567 9.5465 53.6088 15.7046
(B6.5XFAD x BXD68)F1-Ntg both 32.4283 8.1751 48.658 16.1987
(B6.5XFAD x BXD75)F1-ADtg both 23.8663 9.0566 41.8458 5.8867
(B6.5XFAD x BXD77)F1-Ntg both 10.3725 10.4576 31.1335 -10.3885
(B6.5XFAD x BXD87)F1-Ntg both 43.945 8.5386 60.8963 26.9937
(B6.5XFAD x D2)F1-ADtg both 33.5116 3.9048 41.2636 25.7596
(B6.5XFAD x D2)F1-Ntg both 37.0595 4.8592 46.7064 27.4127




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA