Phenotype measure:   Neuner1   cfc_6mo_shock2

ID, description, units MPD:65964   cfc_6mo_shock2   percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning   [%]  2nd shock
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning 2nd shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means26.904   % 22.519   %
Median of the strain means24.941   % 21.218   %
SD of the strain means± 16.054 ± 14.54
Coefficient of variation (CV)0.5967 0.6457
Min–max range of strain means0.0   –   62.66   % 0.0   –   59.66   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 149.7394 149.7394 0.4336 0.5118
strain 13 5901.8532 453.9887 1.3146 0.2182
sex:strain 13 3394.7288 261.133 0.7562 0.7034
Residuals 95 32807.8188 345.3455


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 46.825 1.1667   2   0.825 0.0249 46.0, 47.65 1.24
(B6.5XFAD x B6)F1-ADtg m 32.606 15.654   7 5.9166 0.4801 8.0, 50.0 0.69
(B6.5XFAD x B6)F1-Ntg f 33.177 19.837   6 8.0985 0.5979 9.33, 58.39 0.39
(B6.5XFAD x B6)F1-Ntg m 24.83 10.376   4 5.1881 0.4179 15.33, 37.33 0.16
(B6.5XFAD x BXD100)F1-ADtg f 26.997 16.693   4 8.3467 0.6183 3.33, 41.33 0.01
(B6.5XFAD x BXD100)F1-ADtg m 1.665 2.3547   2   1.665 1.4142 -1.43
(B6.5XFAD x BXD100)F1-Ntg f 7.33 2.8284   2   2.0 0.3859 5.33, 9.33 -1.22
(B6.5XFAD x BXD14)F1-ADtg f 26.626 9.7188   5 4.3464 0.365 14.77, 35.57 -0.02
(B6.5XFAD x BXD14)F1-Ntg f 38.19 26.672   2   18.86 0.6984 19.33, 57.05 0.7
(B6.5XFAD x BXD16)F1-ADtg f 20.332 13.385   4 6.6923 0.6583 3.33, 32.0 -0.41
(B6.5XFAD x BXD22)F1-ADtg f 10.473 9.3548   3 5.401 0.8932 -1.02
(B6.5XFAD x BXD22)F1-Ntg f 34.23 0.0   1   0.0 0.0 34.23, 34.23 0.46
(B6.5XFAD x BXD2)F1-ADtg f 18.84 16.141   4 8.0703 0.8567 4.03, 41.33 -0.5
(B6.5XFAD x BXD2)F1-Ntg f 23.866 16.115   5 7.2069 0.6752 7.33, 46.67 -0.19
(B6.5XFAD x BXD32)F1-ADtg f 32.332 28.36   4 14.18 0.8771 0.34
(B6.5XFAD x BXD32)F1-ADtg m 24.0 5.6569   2   4.0 0.2357 20.0, 28.0 0.1
(B6.5XFAD x BXD32)F1-Ntg f 0.0 0.0   1   0.0 None -1.68
(B6.5XFAD x BXD32)F1-Ntg m 12.33 4.2426   2   3.0 0.3441 9.33, 15.33 -0.7
(B6.5XFAD x BXD34)F1-ADtg f 32.389 18.961   9 6.3202 0.5854 8.0, 63.33 0.34
(B6.5XFAD x BXD34)F1-Ntg f 36.22 11.333   11 3.4169 0.3129 21.48, 57.33 0.58
(B6.5XFAD x BXD42)F1-ADtg f 12.935 12.433   6 5.0757 0.9612 -0.87
(B6.5XFAD x BXD42)F1-Ntg f 13.192 9.6865   4 4.8432 0.7342 -0.85
(B6.5XFAD x BXD44)F1-ADtg f 51.0 19.332   2   13.67 0.3791 37.33, 64.67 1.5
(B6.5XFAD x BXD44)F1-ADtg m 29.335 27.344   2   19.335 0.9321 10.0, 48.67 0.47
(B6.5XFAD x BXD44)F1-Ntg f 41.665 6.1306   2   4.335 0.1471 37.33, 46.0 0.92
(B6.5XFAD x BXD44)F1-Ntg m 9.33 0.0   1   0.0 0.0 9.33, 9.33 -0.91
(B6.5XFAD x BXD51)F1-ADtg f 61.23 10.215   3 5.8979 0.1668 53.02, 72.67 2.14
(B6.5XFAD x BXD51)F1-Ntg f 20.443 9.3615   3 5.4049 0.4579 10.67, 29.33 -0.4
(B6.5XFAD x BXD55)F1-ADtg f 6.89 11.934   3 6.89 1.7321 -1.25
(B6.5XFAD x BXD55)F1-Ntg f 16.543 11.419   4 5.7093 0.6903 -0.65
(B6.5XFAD x BXD56)F1-ADtg f 20.47 4.2709   2   3.02 0.2086 17.45, 23.49 -0.4
(B6.5XFAD x BXD56)F1-Ntg f 40.757 20.666   3 11.931 0.507 20.0, 61.33 0.86
(B6.5XFAD x BXD60)F1-ADtg f 35.0 12.728   2   9.0 0.3637 26.0, 44.0 0.5
(B6.5XFAD x BXD60)F1-ADtg m 31.0 36.303   2   25.67 1.1711 5.33, 56.67 0.58
(B6.5XFAD x BXD60)F1-Ntg f 3.335 4.7164   2   3.335 1.4142 -1.47
(B6.5XFAD x BXD61)F1-ADtg f 20.335 16.497   2   11.665 0.8113 8.67, 32.0 -0.41
(B6.5XFAD x BXD61)F1-ADtg m 35.665 14.616   2   10.335 0.4098 25.33, 46.0 0.9
(B6.5XFAD x BXD61)F1-Ntg f 61.33 0.0   1   0.0 0.0 61.33, 61.33 2.14
(B6.5XFAD x BXD61)F1-Ntg m 34.335 16.497   2   11.665 0.4805 22.67, 46.0 0.81
(B6.5XFAD x BXD62)F1-ADtg f 3.33 0.0   1   0.0 0.0 3.33, 3.33 -1.47
(B6.5XFAD x BXD62)F1-ADtg m 59.66 0.47376   2   0.335 0.0079 59.33, 60.0 2.55
(B6.5XFAD x BXD62)F1-Ntg f 62.66 1.888   2   1.335 0.0301 61.33, 64.0 2.23
(B6.5XFAD x BXD62)F1-Ntg m 4.67 0.0   1   0.0 0.0 4.67, 4.67 -1.23
(B6.5XFAD x BXD65)F1-ADtg f 17.557 17.339   3 10.011 0.9876 -0.58
(B6.5XFAD x BXD65)F1-ADtg m 19.67 7.0711   2   5.0 0.3595 14.67, 24.67 -0.2
(B6.5XFAD x BXD65)F1-Ntg f 10.07 0.0   1   0.0 0.0 10.07, 10.07 -1.05
(B6.5XFAD x BXD65)F1-Ntg m 21.218 12.199   4 6.0995 0.575 5.33, 31.54 -0.09
(B6.5XFAD x BXD66)F1-ADtg f 0.0 0.0   1   0.0 None -1.68
(B6.5XFAD x BXD66)F1-ADtg m 49.833 23.309   4 11.654 0.4677 15.33, 64.0 1.88
(B6.5XFAD x BXD66)F1-Ntg f 52.0 0.0   1   0.0 0.0 52.0, 52.0 1.56
(B6.5XFAD x BXD66)F1-Ntg m 15.33 0.0   1   0.0 0.0 15.33, 15.33 -0.49
(B6.5XFAD x BXD68)F1-ADtg f 33.557 17.162   6 7.0062 0.5114 8.67, 56.67 0.41
(B6.5XFAD x BXD68)F1-ADtg m 0.0 0.0   1   0.0 None -1.55
(B6.5XFAD x BXD68)F1-Ntg f 29.689 12.916   9 4.3054 0.435 12.67, 52.67 0.17
(B6.5XFAD x BXD68)F1-Ntg m 33.0 36.303   2   25.67 1.1001 7.33, 58.67 0.72
(B6.5XFAD x BXD69)F1-ADtg f 45.0 2.3617   2   1.67 0.0525 43.33, 46.67 1.13
(B6.5XFAD x BXD69)F1-ADtg m 6.67 0.0   1   0.0 0.0 6.67, 6.67 -1.09
(B6.5XFAD x BXD69)F1-Ntg f 23.33 0.0   1   0.0 0.0 23.33, 23.33 -0.22
(B6.5XFAD x BXD75)F1-ADtg f 29.852 14.176   4 7.0878 0.4749 12.08, 44.0 0.18
(B6.5XFAD x BXD75)F1-ADtg m 10.0 13.195   2   9.33 1.3195 0.67, 19.33 -0.86
(B6.5XFAD x BXD75)F1-Ntg f 22.097 9.7427   3 5.6249 0.4409 12.08, 31.54 -0.3
(B6.5XFAD x BXD75)F1-Ntg m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.59
(B6.5XFAD x BXD77)F1-ADtg f 31.665 19.325   2   13.665 0.6103 18.0, 45.33 0.3
(B6.5XFAD x BXD77)F1-ADtg m 23.33 0.0   1   0.0 0.0 23.33, 23.33 0.06
(B6.5XFAD x BXD77)F1-Ntg f 6.335 8.959   2   6.335 1.4142 -1.28
(B6.5XFAD x BXD77)F1-Ntg m 10.67 11.314   2   8.0 1.0603 2.67, 18.67 -0.81
(B6.5XFAD x BXD81)F1-ADtg f 17.805 12.547   6 5.1223 0.7047 1.33, 36.67 -0.57
(B6.5XFAD x BXD81)F1-Ntg f 12.89 8.3903   3 4.8441 0.6509 4.0, 20.67 -0.87
(B6.5XFAD x BXD87)F1-ADtg f 35.11 24.713   3 14.268 0.7039 17.33, 63.33 0.51
(B6.5XFAD x BXD87)F1-ADtg m 40.0 0.0   1   0.0 0.0 40.0, 40.0 1.2
(B6.5XFAD x BXD87)F1-Ntg f 26.017 16.8   3 9.6998 0.6458 7.38, 40.0 -0.06
(B6.5XFAD x BXD87)F1-Ntg m 21.11 29.665   3 17.127 1.4053 2.67, 55.33 -0.1
(B6.5XFAD x BXD99)F1-ADtg f 50.22 28.907   3 16.69 0.5756 30.0, 83.33 1.45
(B6.5XFAD x D2)F1-ADtg f 22.457 17.52   16 4.38 0.7801 -0.28
(B6.5XFAD x D2)F1-ADtg m 31.664 25.519   13 7.0777 0.8059 2.67, 71.14 0.63
(B6.5XFAD x D2)F1-Ntg f 20.608 13.814   11 4.1649 0.6703 -0.39
(B6.5XFAD x D2)F1-Ntg m 12.086 15.728   8 5.5606 1.3013 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 46.825 13.1405 72.9122 20.7378
(B6.5XFAD x B6)F1-ADtg m 32.6057 7.0239 46.5499 18.6615
(B6.5XFAD x B6)F1-Ntg f 33.1767 7.5867 48.2381 18.1152
(B6.5XFAD x B6)F1-Ntg m 24.83 9.2917 43.2764 6.3836
(B6.5XFAD x BXD100)F1-ADtg f 26.9975 9.2917 45.4439 8.5511
(B6.5XFAD x BXD100)F1-ADtg m 1.665 13.1405 27.7522 -24.4222
(B6.5XFAD x BXD32)F1-ADtg f 32.3325 9.2917 50.7789 13.8861
(B6.5XFAD x BXD32)F1-ADtg m 24.0 13.1405 50.0872 -2.0872
(B6.5XFAD x BXD44)F1-ADtg f 51.0 13.1405 77.0872 24.9128
(B6.5XFAD x BXD44)F1-ADtg m 29.335 13.1405 55.4222 3.2478
(B6.5XFAD x BXD60)F1-ADtg f 35.0 13.1405 61.0872 8.9128
(B6.5XFAD x BXD60)F1-ADtg m 31.0 13.1405 57.0872 4.9128
(B6.5XFAD x BXD61)F1-ADtg f 20.335 13.1405 46.4222 -5.7522
(B6.5XFAD x BXD61)F1-ADtg m 35.665 13.1405 61.7522 9.5778
(B6.5XFAD x BXD65)F1-ADtg f 17.5567 10.7292 38.8568 -3.7434
(B6.5XFAD x BXD65)F1-ADtg m 19.67 13.1405 45.7572 -6.4172
(B6.5XFAD x BXD68)F1-Ntg f 29.6889 6.1945 41.9865 17.3913
(B6.5XFAD x BXD68)F1-Ntg m 33.0 13.1405 59.0872 6.9128
(B6.5XFAD x BXD75)F1-ADtg f 29.8525 9.2917 48.2989 11.4061
(B6.5XFAD x BXD75)F1-ADtg m 10.0 13.1405 36.0872 -16.0872
(B6.5XFAD x BXD77)F1-Ntg f 6.335 13.1405 32.4222 -19.7522
(B6.5XFAD x BXD77)F1-Ntg m 10.67 13.1405 36.7572 -15.4172
(B6.5XFAD x BXD87)F1-Ntg f 26.0167 10.7292 47.3168 4.7166
(B6.5XFAD x BXD87)F1-Ntg m 21.11 10.7292 42.4101 -0.1901
(B6.5XFAD x D2)F1-ADtg f 22.4575 4.6459 31.6807 13.2343
(B6.5XFAD x D2)F1-ADtg m 31.6638 5.1541 41.8961 21.4316
(B6.5XFAD x D2)F1-Ntg f 20.6082 5.6031 31.7318 9.4846
(B6.5XFAD x D2)F1-Ntg m 12.0862 6.5702 25.1298 -0.9573


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 39.7154 7.45 54.5054 24.9253
(B6.5XFAD x B6)F1-Ntg both 29.0033 5.9978 40.9105 17.0962
(B6.5XFAD x BXD100)F1-ADtg both 14.3312 8.0469 30.3063 -1.6438
(B6.5XFAD x BXD32)F1-ADtg both 28.1662 8.0469 44.1413 12.1912
(B6.5XFAD x BXD44)F1-ADtg both 40.1675 9.2917 58.6139 21.7211
(B6.5XFAD x BXD60)F1-ADtg both 33.0 9.2917 51.4464 14.5536
(B6.5XFAD x BXD61)F1-ADtg both 28.0 9.2917 46.4464 9.5536
(B6.5XFAD x BXD65)F1-ADtg both 18.6133 8.4822 35.4525 1.7741
(B6.5XFAD x BXD68)F1-Ntg both 31.3444 7.2637 45.7647 16.9242
(B6.5XFAD x BXD75)F1-ADtg both 19.9262 8.0469 35.9013 3.9512
(B6.5XFAD x BXD77)F1-Ntg both 8.5025 9.2917 26.9489 -9.9439
(B6.5XFAD x BXD87)F1-Ntg both 23.5633 7.5867 38.6248 8.5019
(B6.5XFAD x D2)F1-ADtg both 27.0607 3.4695 33.9485 20.1729
(B6.5XFAD x D2)F1-Ntg both 16.3472 4.3175 24.9185 7.7759




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA