Project measure / variable:   Neuner1   cfc_6mo_shock1

ID, description, units MPD:65963   cfc_6mo_shock1   percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning   [%]  1st shock  
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning 1st shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means15.269   % 14.933   %
Median of the strain means12.137   % 14.67   %
SD of the strain means± 11.93 ± 12.023
Coefficient of variation (CV)0.7813 0.8051
Min–max range of strain means0.0   –   44.95   % 0.0   –   48.335   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.4207 3.4207 0.0149 0.903
strain 13 6469.5361 497.6566 2.1715 0.0165
sex:strain 13 3088.6173 237.5859 1.0367 0.4238
Residuals 95 21771.8221 229.1771


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 36.465 2.5385   2   1.795 0.0696 34.67, 38.26 1.78
(B6.5XFAD x B6)F1-ADtg m 15.926 13.953   7 5.2738 0.8761 0.08
(B6.5XFAD x B6)F1-Ntg f 25.443 18.578   6 7.5844 0.7302 0.85
(B6.5XFAD x B6)F1-Ntg m 1.675 2.0122   4 1.0061 1.2013 -1.1
(B6.5XFAD x BXD100)F1-ADtg f 9.055 9.249   4 4.6245 1.0214 -0.52
(B6.5XFAD x BXD100)F1-ADtg m 0.0 0.0   2   0.0 None -1.24
(B6.5XFAD x BXD100)F1-Ntg f 5.335 7.5448   2   5.335 1.4142 -0.83
(B6.5XFAD x BXD14)F1-ADtg f 17.068 12.951   5 5.7918 0.7588 1.33, 32.67 0.15
(B6.5XFAD x BXD14)F1-Ntg f 10.725 9.5106   2   6.725 0.8868 4.0, 17.45 -0.38
(B6.5XFAD x BXD16)F1-ADtg f 5.665 5.6689   4 2.8344 1.0007 -0.81
(B6.5XFAD x BXD22)F1-ADtg f 6.0 7.6908   3 4.4403 1.2818 -0.78
(B6.5XFAD x BXD22)F1-Ntg f 32.0 0.0   1   0.0 0.0 32.0, 32.0 1.4
(B6.5XFAD x BXD2)F1-ADtg f 13.165 17.857   4 8.9286 1.3564 -0.18
(B6.5XFAD x BXD2)F1-Ntg f 2.666 2.7897   5 1.2476 1.0464 -1.06
(B6.5XFAD x BXD32)F1-ADtg f 10.335 8.8024   4 4.4012 0.8517 -0.41
(B6.5XFAD x BXD32)F1-ADtg m 14.0 19.799   2   14.0 1.4142 -0.08
(B6.5XFAD x BXD32)F1-Ntg f 0.0 0.0   1   0.0 None -1.28
(B6.5XFAD x BXD32)F1-Ntg m 8.33 4.2426   2   3.0 0.5093 5.33, 11.33 -0.55
(B6.5XFAD x BXD34)F1-ADtg f 17.556 14.141   9 4.7136 0.8055 0.19
(B6.5XFAD x BXD34)F1-Ntg f 18.863 16.465   11 4.9644 0.8729 0.3
(B6.5XFAD x BXD42)F1-ADtg f 4.445 5.2953   6 2.1618 1.1913 -0.91
(B6.5XFAD x BXD42)F1-Ntg f 8.335 12.621   4 6.3106 1.5142 -0.58
(B6.5XFAD x BXD44)F1-ADtg f 40.665 3.7689   2   2.665 0.0927 38.0, 43.33 2.13
(B6.5XFAD x BXD44)F1-ADtg m 33.665 5.1831   2   3.665 0.154 30.0, 37.33 1.56
(B6.5XFAD x BXD44)F1-Ntg f 21.33 16.971   2   12.0 0.7956 9.33, 33.33 0.51
(B6.5XFAD x BXD44)F1-Ntg m 0.0 0.0   1   0.0 None -1.24
(B6.5XFAD x BXD51)F1-ADtg f 32.89 7.5779   3 4.3751 0.2304 26.67, 41.33 1.48
(B6.5XFAD x BXD51)F1-Ntg f 5.11 8.8508   3 5.11 1.7321 -0.85
(B6.5XFAD x BXD55)F1-ADtg f 3.5567 6.1603   3 3.5567 1.7321 -0.98
(B6.5XFAD x BXD55)F1-Ntg f 8.1675 15.031   4 7.5156 1.8404 -0.6
(B6.5XFAD x BXD56)F1-ADtg f 16.33 15.556   2   11.0 0.9526 5.33, 27.33 0.09
(B6.5XFAD x BXD56)F1-Ntg f 16.443 13.0   3 7.5055 0.7906 7.33, 31.33 0.1
(B6.5XFAD x BXD60)F1-ADtg f 14.67 11.314   2   8.0 0.7712 6.67, 22.67 -0.05
(B6.5XFAD x BXD60)F1-ADtg m 6.04 8.5418   2   6.04 1.4142 -0.74
(B6.5XFAD x BXD60)F1-Ntg f 2.0 2.8284   2   2.0 1.4142 -1.11
(B6.5XFAD x BXD61)F1-ADtg f 15.44 0.0   2   0.0 0.0 15.44, 15.44 0.01
(B6.5XFAD x BXD61)F1-ADtg m 14.67 5.6569   2   4.0 0.3856 10.67, 18.67 -0.02
(B6.5XFAD x BXD61)F1-Ntg f 28.19 0.0   1   0.0 0.0 28.19, 28.19 1.08
(B6.5XFAD x BXD61)F1-Ntg m 5.0 6.1235   2   4.33 1.2247 0.67, 9.33 -0.83
(B6.5XFAD x BXD62)F1-ADtg f 0.0 0.0   1   0.0 None -1.28
(B6.5XFAD x BXD62)F1-ADtg m 48.335 0.47376   2   0.335 0.0098 48.0, 48.67 2.78
(B6.5XFAD x BXD62)F1-Ntg f 36.33 24.042   2   17.0 0.6618 19.33, 53.33 1.77
(B6.5XFAD x BXD62)F1-Ntg m 18.0 0.0   1   0.0 0.0 18.0, 18.0 0.26
(B6.5XFAD x BXD65)F1-ADtg f 3.11 2.7742   3 1.6017 0.892 -1.02
(B6.5XFAD x BXD65)F1-ADtg m 0.665 0.94045   2   0.665 1.4142 -1.19
(B6.5XFAD x BXD65)F1-Ntg f 5.33 0.0   1   0.0 0.0 5.33, 5.33 -0.83
(B6.5XFAD x BXD65)F1-Ntg m 2.5 5.0   4 2.5 2.0 -1.03
(B6.5XFAD x BXD66)F1-ADtg f 0.0 0.0   1   0.0 None -1.28
(B6.5XFAD x BXD66)F1-ADtg m 32.36 12.257   4 6.1283 0.3788 14.0, 38.93 1.45
(B6.5XFAD x BXD66)F1-Ntg f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.61
(B6.5XFAD x BXD66)F1-Ntg m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.08
(B6.5XFAD x BXD68)F1-ADtg f 25.342 9.8244   6 4.0108 0.3877 8.05, 35.33 0.84
(B6.5XFAD x BXD68)F1-ADtg m 16.67 0.0   1   0.0 0.0 16.67, 16.67 0.14
(B6.5XFAD x BXD68)F1-Ntg f 8.2956 10.567   9 3.5223 1.2738 -0.58
(B6.5XFAD x BXD68)F1-Ntg m 20.665 29.225   2   20.665 1.4142 0.48
(B6.5XFAD x BXD69)F1-ADtg f 15.035 6.074   2   4.295 0.404 10.74, 19.33 -0.02
(B6.5XFAD x BXD69)F1-ADtg m 3.33 0.0   1   0.0 0.0 3.33, 3.33 -0.97
(B6.5XFAD x BXD69)F1-Ntg f 6.71 0.0   1   0.0 0.0 6.71, 6.71 -0.72
(B6.5XFAD x BXD75)F1-ADtg f 15.335 6.6425   4 3.3213 0.4332 8.67, 22.0 0.01
(B6.5XFAD x BXD75)F1-ADtg m 22.665 16.03   2   11.335 0.7073 11.33, 34.0 0.64
(B6.5XFAD x BXD75)F1-Ntg f 30.223 9.338   3 5.3913 0.309 20.67, 39.33 1.25
(B6.5XFAD x BXD75)F1-Ntg m 20.67 0.0   1   0.0 0.0 20.67, 20.67 0.48
(B6.5XFAD x BXD77)F1-ADtg f 39.505 15.323   2   10.835 0.3879 28.67, 50.34 2.03
(B6.5XFAD x BXD77)F1-ADtg m 26.17 0.0   1   0.0 0.0 26.17, 26.17 0.93
(B6.5XFAD x BXD77)F1-Ntg f 8.705 3.8254   2   2.705 0.4395 6.0, 11.41 -0.55
(B6.5XFAD x BXD77)F1-Ntg m 1.335 1.888   2   1.335 1.4142 -1.13
(B6.5XFAD x BXD81)F1-ADtg f 8.2233 12.057   6 4.9222 1.4662 -0.59
(B6.5XFAD x BXD81)F1-Ntg f 11.11 9.7158   3 5.6094 0.8745 3.33, 22.0 -0.35
(B6.5XFAD x BXD87)F1-ADtg f 21.333 19.741   3 11.398 0.9254 2.67, 42.0 0.51
(B6.5XFAD x BXD87)F1-ADtg m 24.67 0.0   1   0.0 0.0 24.67, 24.67 0.81
(B6.5XFAD x BXD87)F1-Ntg f 28.667 8.8217   3 5.0932 0.3077 22.0, 38.67 1.12
(B6.5XFAD x BXD87)F1-Ntg m 21.11 20.592   3 11.889 0.9755 2.67, 43.33 0.51
(B6.5XFAD x BXD99)F1-ADtg f 44.95 17.626   3 10.176 0.3921 28.19, 63.33 2.49
(B6.5XFAD x D2)F1-ADtg f 14.918 22.706   16 5.6765 1.522 -0.03
(B6.5XFAD x D2)F1-ADtg m 21.151 22.477   13 6.2339 1.0627 0.52
(B6.5XFAD x D2)F1-Ntg f 4.4373 5.6359   11 1.6993 1.2701 -0.91
(B6.5XFAD x D2)F1-Ntg m 9.585 7.709   8 2.7255 0.8043 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 36.465 10.7046 57.7163 15.2137
(B6.5XFAD x B6)F1-ADtg m 15.9257 5.7219 27.285 4.5664
(B6.5XFAD x B6)F1-Ntg f 25.4433 6.1803 37.7128 13.1739
(B6.5XFAD x B6)F1-Ntg m 1.675 7.5693 16.702 -13.352
(B6.5XFAD x BXD100)F1-ADtg f 9.055 7.5693 24.082 -5.972
(B6.5XFAD x BXD100)F1-ADtg m 0.0 10.7046 21.2513 -21.2513
(B6.5XFAD x BXD32)F1-ADtg f 10.335 7.5693 25.362 -4.692
(B6.5XFAD x BXD32)F1-ADtg m 14.0 10.7046 35.2513 -7.2513
(B6.5XFAD x BXD44)F1-ADtg f 40.665 10.7046 61.9163 19.4137
(B6.5XFAD x BXD44)F1-ADtg m 33.665 10.7046 54.9163 12.4137
(B6.5XFAD x BXD60)F1-ADtg f 14.67 10.7046 35.9213 -6.5813
(B6.5XFAD x BXD60)F1-ADtg m 6.04 10.7046 27.2913 -15.2113
(B6.5XFAD x BXD61)F1-ADtg f 15.44 10.7046 36.6913 -5.8113
(B6.5XFAD x BXD61)F1-ADtg m 14.67 10.7046 35.9213 -6.5813
(B6.5XFAD x BXD65)F1-ADtg f 3.11 8.7403 20.4616 -14.2416
(B6.5XFAD x BXD65)F1-ADtg m 0.665 10.7046 21.9163 -20.5863
(B6.5XFAD x BXD68)F1-Ntg f 8.2956 5.0462 18.3135 -1.7224
(B6.5XFAD x BXD68)F1-Ntg m 20.665 10.7046 41.9163 -0.5863
(B6.5XFAD x BXD75)F1-ADtg f 15.335 7.5693 30.362 0.308
(B6.5XFAD x BXD75)F1-ADtg m 22.665 10.7046 43.9163 1.4137
(B6.5XFAD x BXD77)F1-Ntg f 8.705 10.7046 29.9563 -12.5463
(B6.5XFAD x BXD77)F1-Ntg m 1.335 10.7046 22.5863 -19.9163
(B6.5XFAD x BXD87)F1-Ntg f 28.6667 8.7403 46.0183 11.315
(B6.5XFAD x BXD87)F1-Ntg m 21.11 8.7403 38.4616 3.7584
(B6.5XFAD x D2)F1-ADtg f 14.9181 3.7846 22.4316 7.4046
(B6.5XFAD x D2)F1-ADtg m 21.1508 4.1987 29.4862 12.8153
(B6.5XFAD x D2)F1-Ntg f 4.4373 4.5645 13.4989 -4.6243
(B6.5XFAD x D2)F1-Ntg m 9.585 5.3523 20.2107 -1.0407


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 26.1954 6.0689 38.2437 14.147
(B6.5XFAD x B6)F1-Ntg both 13.5592 4.886 23.259 3.8593
(B6.5XFAD x BXD100)F1-ADtg both 4.5275 6.5552 17.5412 -8.4862
(B6.5XFAD x BXD32)F1-ADtg both 12.1675 6.5552 25.1812 -0.8462
(B6.5XFAD x BXD44)F1-ADtg both 37.165 7.5693 52.192 22.138
(B6.5XFAD x BXD60)F1-ADtg both 10.355 7.5693 25.382 -4.672
(B6.5XFAD x BXD61)F1-ADtg both 15.055 7.5693 30.082 0.028
(B6.5XFAD x BXD65)F1-ADtg both 1.8875 6.9098 15.6052 -11.8302
(B6.5XFAD x BXD68)F1-Ntg both 14.4803 5.9172 26.2274 2.7332
(B6.5XFAD x BXD75)F1-ADtg both 19.0 6.5552 32.0137 5.9863
(B6.5XFAD x BXD77)F1-Ntg both 5.02 7.5693 20.047 -10.007
(B6.5XFAD x BXD87)F1-Ntg both 24.8883 6.1803 37.1578 12.6189
(B6.5XFAD x D2)F1-ADtg both 18.0344 2.8263 23.6454 12.4235
(B6.5XFAD x D2)F1-Ntg both 7.0111 3.5172 13.9936 0.0287




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA