Phenotype measure:   Neuner1   cfc_6mo_baseline

ID, description, units MPD:65962   cfc_6mo_baseline   percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning   [%]  baseline
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means3.1564   % 2.7503   %
Median of the strain means1.9775   % 0.595   %
SD of the strain means± 3.0119 ± 4.4768
Coefficient of variation (CV)0.9542 1.6277
Min–max range of strain means0.0   –   12.229   % 0.0   –   18.12   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 142.7042 142.7042 10.6267 0.0015
strain 13 474.3481 36.4883 2.7172 0.0027
sex:strain 13 310.1039 23.8541 1.7763 0.058
Residuals 95 1275.7442 13.4289


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 9.125 6.1872   2   4.375 0.678 4.75, 13.5 1.98
(B6.5XFAD x B6)F1-ADtg m 0.0 0.0   7 0.0 None -0.61
(B6.5XFAD x B6)F1-Ntg f 4.8217 5.3487   6 2.1836 1.1093 0.55
(B6.5XFAD x B6)F1-Ntg m 0.56 1.12   4 0.56 2.0 -0.49
(B6.5XFAD x BXD100)F1-ADtg f 6.345 5.8944   4 2.9472 0.929 1.64, 14.48 1.06
(B6.5XFAD x BXD100)F1-ADtg m 0.595 0.84146   2   0.595 1.4142 -0.48
(B6.5XFAD x BXD100)F1-Ntg f 0.0 0.0   2   0.0 None -1.05
(B6.5XFAD x BXD14)F1-ADtg f 1.134 1.5667   5 0.70067 1.3816 -0.67
(B6.5XFAD x BXD14)F1-Ntg f 2.015 1.789   2   1.265 0.8878 0.75, 3.28 -0.38
(B6.5XFAD x BXD16)F1-ADtg f 1.0075 1.5557   4 0.77785 1.5441 -0.71
(B6.5XFAD x BXD22)F1-ADtg f 0.0 0.0   3 0.0 None -1.05
(B6.5XFAD x BXD22)F1-Ntg f 0.0 0.0   1   0.0 None -1.05
(B6.5XFAD x BXD2)F1-ADtg f 5.515 5.4016   4 2.7008 0.9794 1.04, 12.52 0.78
(B6.5XFAD x BXD2)F1-Ntg f 0.776 1.3554   5 0.60616 1.7467 -0.79
(B6.5XFAD x BXD32)F1-ADtg f 2.5025 3.0537   4 1.5268 1.2202 -0.22
(B6.5XFAD x BXD32)F1-ADtg m 0.3 0.42426   2   0.3 1.4142 -0.55
(B6.5XFAD x BXD32)F1-Ntg f 0.3 0.0   1   0.0 0.0 0.3, 0.3 -0.95
(B6.5XFAD x BXD32)F1-Ntg m 0.0 0.0   2   0.0 None -0.61
(B6.5XFAD x BXD34)F1-ADtg f 12.229 6.8942   9 2.2981 0.5638 1.49, 19.1 3.01
(B6.5XFAD x BXD34)F1-Ntg f 7.74 5.9409   11 1.7912 0.7676 1.52
(B6.5XFAD x BXD42)F1-ADtg f 1.195 2.2229   6 0.90748 1.8601 -0.65
(B6.5XFAD x BXD42)F1-Ntg f 1.1575 1.7667   4 0.88335 1.5263 -0.66
(B6.5XFAD x BXD44)F1-ADtg f 4.4 5.374   2   3.8 1.2214 0.6, 8.2 0.41
(B6.5XFAD x BXD44)F1-ADtg m 2.315 3.2739   2   2.315 1.4142 -0.1
(B6.5XFAD x BXD44)F1-Ntg f 6.555 5.9043   2   4.175 0.9007 2.38, 10.73 1.13
(B6.5XFAD x BXD44)F1-Ntg m 0.0 0.0   1   0.0 None -0.61
(B6.5XFAD x BXD51)F1-ADtg f 6.17 7.1238   3 4.113 1.1546 1.19, 14.33 1.0
(B6.5XFAD x BXD51)F1-Ntg f 1.29 2.2343   3 1.29 1.7321 -0.62
(B6.5XFAD x BXD55)F1-ADtg f 0.29667 0.51384   3 0.29667 1.7321 -0.95
(B6.5XFAD x BXD55)F1-Ntg f 0.4125 0.48023   4 0.24012 1.1642 -0.91
(B6.5XFAD x BXD56)F1-ADtg f 9.03 0.31113   2   0.22 0.0345 8.81, 9.25 1.95
(B6.5XFAD x BXD56)F1-Ntg f 7.2533 9.6306   3 5.5602 1.3277 1.36
(B6.5XFAD x BXD60)F1-ADtg f 0.0 0.0   2   0.0 None -1.05
(B6.5XFAD x BXD60)F1-ADtg m 9.85 13.93   2   9.85 1.4142 1.59
(B6.5XFAD x BXD60)F1-Ntg f 0.375 0.53033   2   0.375 1.4142 -0.92
(B6.5XFAD x BXD61)F1-ADtg f 3.055 4.3204   2   3.055 1.4142 -0.03
(B6.5XFAD x BXD61)F1-ADtg m 0.3 0.42426   2   0.3 1.4142 -0.55
(B6.5XFAD x BXD61)F1-Ntg f 1.79 0.0   1   0.0 0.0 1.79, 1.79 -0.45
(B6.5XFAD x BXD61)F1-Ntg m 1.64 2.3193   2   1.64 1.4142 -0.25
(B6.5XFAD x BXD62)F1-ADtg f 0.6 0.0   1   0.0 0.0 0.6, 0.6 -0.85
(B6.5XFAD x BXD62)F1-ADtg m 18.12 4.7659   2   3.37 0.263 14.75, 21.49 3.43
(B6.5XFAD x BXD62)F1-Ntg f 4.695 0.74246   2   0.525 0.1581 4.17, 5.22 0.51
(B6.5XFAD x BXD62)F1-Ntg m 9.39 0.0   1   0.0 0.0 9.39, 9.39 1.48
(B6.5XFAD x BXD65)F1-ADtg f 3.9767 3.438   3 1.9849 0.8646 1.49, 7.9 0.27
(B6.5XFAD x BXD65)F1-ADtg m 0.0 0.0   2   0.0 None -0.61
(B6.5XFAD x BXD65)F1-Ntg f 1.94 0.0   1   0.0 0.0 1.94, 1.94 -0.4
(B6.5XFAD x BXD65)F1-Ntg m 0.1875 0.375   4 0.1875 2.0 -0.57
(B6.5XFAD x BXD66)F1-ADtg f 0.0 0.0   1   0.0 None -1.05
(B6.5XFAD x BXD66)F1-ADtg m 0.3 0.34641   4 0.17321 1.1547 -0.55
(B6.5XFAD x BXD66)F1-Ntg f 0.0 0.0   1   0.0 None -1.05
(B6.5XFAD x BXD66)F1-Ntg m 0.0 0.0   1   0.0 None -0.61
(B6.5XFAD x BXD68)F1-ADtg f 5.0933 5.3304   6 2.1761 1.0465 0.64
(B6.5XFAD x BXD68)F1-ADtg m 9.39 0.0   1   0.0 0.0 9.39, 9.39 1.48
(B6.5XFAD x BXD68)F1-Ntg f 8.7511 8.0923   9 2.6974 0.9247 1.86
(B6.5XFAD x BXD68)F1-Ntg m 3.81 1.3718   2   0.97 0.36 2.84, 4.78 0.24
(B6.5XFAD x BXD69)F1-ADtg f 1.565 2.2132   2   1.565 1.4142 -0.53
(B6.5XFAD x BXD69)F1-ADtg m 0.0 0.0   1   0.0 None -0.61
(B6.5XFAD x BXD69)F1-Ntg f 4.93 0.0   1   0.0 0.0 4.93, 4.93 0.59
(B6.5XFAD x BXD75)F1-ADtg f 1.4575 1.3602   4 0.6801 0.9332 -0.56
(B6.5XFAD x BXD75)F1-ADtg m 1.64 2.3193   2   1.64 1.4142 -0.25
(B6.5XFAD x BXD75)F1-Ntg f 2.9833 1.5818   3 0.91324 0.5302 1.19, 4.18 -0.06
(B6.5XFAD x BXD75)F1-Ntg m 2.24 0.0   1   0.0 0.0 2.24, 2.24 -0.11
(B6.5XFAD x BXD77)F1-ADtg f 2.165 3.0618   2   2.165 1.4142 -0.33
(B6.5XFAD x BXD77)F1-ADtg m 0.0 0.0   1   0.0 None -0.61
(B6.5XFAD x BXD77)F1-Ntg f 1.12 0.73539   2   0.52 0.6566 0.6, 1.64 -0.68
(B6.5XFAD x BXD77)F1-Ntg m 0.895 1.2657   2   0.895 1.4142 -0.41
(B6.5XFAD x BXD81)F1-ADtg f 0.84667 1.2016   6 0.49055 1.4192 -0.77
(B6.5XFAD x BXD81)F1-Ntg f 3.48 3.3089   3 1.9104 0.9508 0.75, 7.16 0.11
(B6.5XFAD x BXD87)F1-ADtg f 6.4567 6.1394   3 3.5446 0.9509 1.1
(B6.5XFAD x BXD87)F1-ADtg m 9.24 0.0   1   0.0 0.0 9.24, 9.24 1.45
(B6.5XFAD x BXD87)F1-Ntg f 3.8267 3.3346   3 1.9252 0.8714 0.22
(B6.5XFAD x BXD87)F1-Ntg m 2.3367 2.025   3 1.1691 0.8666 -0.09
(B6.5XFAD x BXD99)F1-ADtg f 5.62 3.7971   3 2.1923 0.6756 1.49, 8.96 0.82
(B6.5XFAD x D2)F1-ADtg f 1.1837 1.7858   16 0.44646 1.5086 -0.65
(B6.5XFAD x D2)F1-ADtg m 0.75769 1.7552   13 0.4868 2.3165 -0.45
(B6.5XFAD x D2)F1-Ntg f 0.63727 1.5295   11 0.46116 2.4 -0.84
(B6.5XFAD x D2)F1-Ntg m 0.39125 0.75167   8 0.26576 1.9212 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 9.125 2.5912 14.2692 3.9808
(B6.5XFAD x B6)F1-ADtg m 0.0 1.3851 2.7497 -2.7497
(B6.5XFAD x B6)F1-Ntg f 4.8217 1.496 7.7917 1.8516
(B6.5XFAD x B6)F1-Ntg m 0.56 1.8323 4.1975 -3.0775
(B6.5XFAD x BXD100)F1-ADtg f 6.345 1.8323 9.9825 2.7075
(B6.5XFAD x BXD100)F1-ADtg m 0.595 2.5912 5.7392 -4.5492
(B6.5XFAD x BXD32)F1-ADtg f 2.5025 1.8323 6.14 -1.135
(B6.5XFAD x BXD32)F1-ADtg m 0.3 2.5912 5.4442 -4.8442
(B6.5XFAD x BXD44)F1-ADtg f 4.4 2.5912 9.5442 -0.7442
(B6.5XFAD x BXD44)F1-ADtg m 2.315 2.5912 7.4592 -2.8292
(B6.5XFAD x BXD60)F1-ADtg f 0.0 2.5912 5.1442 -5.1442
(B6.5XFAD x BXD60)F1-ADtg m 9.85 2.5912 14.9942 4.7058
(B6.5XFAD x BXD61)F1-ADtg f 3.055 2.5912 8.1992 -2.0892
(B6.5XFAD x BXD61)F1-ADtg m 0.3 2.5912 5.4442 -4.8442
(B6.5XFAD x BXD65)F1-ADtg f 3.9767 2.1157 8.1769 -0.2236
(B6.5XFAD x BXD65)F1-ADtg m 0.0 2.5912 5.1442 -5.1442
(B6.5XFAD x BXD68)F1-Ntg f 8.7511 1.2215 11.1761 6.3261
(B6.5XFAD x BXD68)F1-Ntg m 3.81 2.5912 8.9542 -1.3342
(B6.5XFAD x BXD75)F1-ADtg f 1.4575 1.8323 5.095 -2.18
(B6.5XFAD x BXD75)F1-ADtg m 1.64 2.5912 6.7842 -3.5042
(B6.5XFAD x BXD77)F1-Ntg f 1.12 2.5912 6.2642 -4.0242
(B6.5XFAD x BXD77)F1-Ntg m 0.895 2.5912 6.0392 -4.2492
(B6.5XFAD x BXD87)F1-Ntg f 3.8267 2.1157 8.0269 -0.3736
(B6.5XFAD x BXD87)F1-Ntg m 2.3367 2.1157 6.5369 -1.8636
(B6.5XFAD x D2)F1-ADtg f 1.1837 0.9161 3.0025 -0.635
(B6.5XFAD x D2)F1-ADtg m 0.7577 1.0164 2.7754 -1.26
(B6.5XFAD x D2)F1-Ntg f 0.6373 1.1049 2.8308 -1.5562
(B6.5XFAD x D2)F1-Ntg m 0.3912 1.2956 2.9634 -2.1809


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 4.5625 1.4691 7.479 1.646
(B6.5XFAD x B6)F1-Ntg both 2.6908 1.1827 5.0388 0.3428
(B6.5XFAD x BXD100)F1-ADtg both 3.47 1.5868 6.6202 0.3198
(B6.5XFAD x BXD32)F1-ADtg both 1.4012 1.5868 4.5514 -1.7489
(B6.5XFAD x BXD44)F1-ADtg both 3.3575 1.8323 6.995 -0.28
(B6.5XFAD x BXD60)F1-ADtg both 4.925 1.8323 8.5625 1.2875
(B6.5XFAD x BXD61)F1-ADtg both 1.6775 1.8323 5.315 -1.96
(B6.5XFAD x BXD65)F1-ADtg both 1.9883 1.6726 5.3089 -1.3323
(B6.5XFAD x BXD68)F1-Ntg both 6.2806 1.4324 9.1241 3.437
(B6.5XFAD x BXD75)F1-ADtg both 1.5487 1.5868 4.6989 -1.6014
(B6.5XFAD x BXD77)F1-Ntg both 1.0075 1.8323 4.645 -2.63
(B6.5XFAD x BXD87)F1-Ntg both 3.0817 1.496 6.0517 0.1116
(B6.5XFAD x D2)F1-ADtg both 0.9707 0.6842 2.3289 -0.3875
(B6.5XFAD x D2)F1-Ntg both 0.5143 0.8514 2.2045 -1.1759




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA